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| 1 | 冬虫夏草对巨噬细胞免疫活性的增强作用显示文摘目的:检测冬虫夏草对巨噬细胞免疫活性的影响,探讨其滋补强身作用机理。方法:采用不同浓度虫草水提液与J774巨噬细胞一起作细胞培养,观察细胞吞噬活性的变异情况。结果:细胞吞噬活性明显增强。在药物浓度100μg·ml-1到3000μg·ml-1范围内都有显著增强效果(P<0.05)。分别增强1.27倍到2.58倍,峰值在500μg·ml-1。结论:增强机体免疫功能,可能在虫草的滋补强身作用机制中起重要作用。 | 贾泰元 Benjamin HS Lau | 1997 | 中国药学杂志1997，32，3： | 30 |
| 2 | 中国大陆地区妇女骨质疏松筛选工具探讨显示文摘目的建立适用于中国大陆地区40岁及以上妇女的骨质疏松(osteoporosis,OP)筛选工具。方法以20~39岁妇女腰椎骨密度的均数和标准差作为参考值计算T—score。以双能X线骨密度仪(dual—energy X—ray absorptiometry,DxA)的测量结果作为金标准,采用二分类的Bayes判别分析,建立判别函数。结果我国大陆地区40岁及以上妇女OP筛选工具(osteoporosis screening tool for Chinese,OSTC)为:体重-2×年龄+50。判别准则为OSTC〉0为无OP危险性,OSTC≤0为有OP危险性。OSTC的正判率为75.78%,灵敏度为76.8%,特异度为75.1%,Kappa值为0.51(P=0.000),说明OSTC与DXA的判定结果一致性尚可。结论OSTC是一个简便的OP筛选工具。根据年龄、体重两个变量的简单计算,即可对我国大陆地区40岁及以上的妇女进行OP危险性的筛选。但OSTC没有得到外部数据的验证,其优劣还有待进一步评价。 | 张菊英 吴涛 杨定焯 程晓光 周琦 卓铁军 张华寿 项静 王洪复 区品中。 刘建立 徐苓 黄公怡 黄琪仁 Barden HS Weynand LS Fqukner KG 孟迅吾 区品中 | 2007 | 中国修复重建外科杂志2007，21，1： | 26 |
| 3 | Metabolic profiling analysis of a D-galactosamine/lipopolysaccharide- induced mouse model of fulminant hepatic failure显示文摘 | Feng, B Wu, SM Lv, S Liu, F Chen, HS Yan, XZ Li, Y Dong, FT Wei, L | 2007 | 中国生物学文摘2007，21，11： | 23 |
| 4 | A clinical and long-term follow-up study of perioperative sequential triple therapy for gastric cancer显示文摘INTRODUCTIONAlthough the long-term postoperative survival rateof gastric cancer(GC) patients has been improvedsignificantly since the local dissection of lymph nodewas widely used in China,yet the low curativeresection rate and the high recurrence rate fromperitoneal and hepatic metastases hinder it fromfurther improvement.To alter the currentunsatisfactory status of GC treatment,a | Zou SC Qiu HS Zhang CW Tao HQ | 2000 | World Journal of Gastroenterology2000，6，2： | 18 |
| 5 | Antifungal activities and action mechanisms of compounds from Tribulus terrestris L.显示文摘 | Zhang JD Xu Z Cao YB Chen HS Yan L An MM Gao PH Wang Y Jia XM Jiang YY | 2006 | 第二军医大学学报2006，27，5： | 14 |
| 6 | Lack of Efficacy of Bevacizumab Plus Irinotecan in Children with Recurrent Malignant Glioma and Diffuse Brainstem Glioma:A Pediatric Brain Tumor Consortium Study显示文摘PURPOSE:A phase Ⅱ study of bevacizumab(BVZ) plus irinotecan(CPT-11) was conducted in children with recurrent malignant glioma(MG) and intrinsic brainstem glioma(BSG).PATIENTS AND METHODS:Eligible patients received two doses of BVZ | Gururangan S Chi SN Young Poussaint T Onar-Thomas A Gilbertson RJ Vajapeyam S Friedman HS Packer RJ Rood BN Boyett JM Kun LE | 2010 | 中国神经肿瘤杂志2010，8，2： | 7 |
| 7 | Anatomic structural study of cerebellopontine angle via endoscope显示文摘在颅骨底依靠寻找内视镜的技术的可能的解剖基础的背景最低限度地侵略的外科是争论的。这研究的目的是在 cerebellopontine 角度区域观察在主要的血容器和神经之间的空间关系并且为侧面、以后的颅骨底提供解剖基础经由内视镜的 retrosigmoid 锁眼 approach.Methods 的最低限度地侵略的外科这研究在三十个弄干的成年颅骨上被进行测量空间关系在之中出现以后的头部的窝的多骨的标记,并且为 retrosigmoid 锁眼 ap 定位最适当的钻区域在直径与 2.0 厘米在这个点上集中的一个洞对在 cerebellopontine 角度暴露相关结构合适。 Retrosigmoid 锁眼途径罐头减少小脑上的压力并且有效地暴露相关结构它包括面部神经, vestibulocochlear 神经,三叉的神经,舌与喉的神经,迷走神经神经,附件神经,舌下神经神经,前面的劣等的小脑的动脉,以后的劣等的小脑的动脉和迷宫的动脉,内诊镜 retrosigmoid 途径上的准确地点能避免在最低限度地侵略的外科期间拖小脑的 etc.Conclusions 。retrosigmoid 锁眼途径的申请将扩大内视镜的技术的申请。 | XIA Yin LI Xi-ping HAN De-min ZHENG Jun LONG Hai-shan SHI Jin-feng Department of Otolaryngology,Beijing Tongren Hospital,Capital Medical University Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University),Ministry of Education,Beijing 100730,China (Xia Y,Li XP,Han DM,Zheng J,Long HS and Shi JF) | 2007 | Chinese Medical Journal2007，，20： | 7 |
| 8 | On abiogenic natural gas显示文摘NATURAL gases usually refer to the inflammable gases dominated by methane from the angle of research on energy gases. Three genetic types of natural gases can be recognized according to the process of methane generation: (ⅰ) biogenic (bacterial) gas, mainly the gas formed by the decomposition of organic matter in sediments under the action of anaerobic bacteria; (ⅱ) thermogenic gas, mainly the gas formed by the degradation of organic matter in sediments under the action of certain temperature and pressure; (ⅲ) abiogenic gas, mainly the | Wang, XB Li, CY Chen, JF Xia, XY Guo, ZQ Xie, HS | 1997 | Chinese Science Bulletin1997，42，16： | 5 |
| 9 | 英法海峡隧道燃料火灾的安全性讨论显示文摘 | Eisn.,HS 马积薪 | 1989 | 隧道译丛1989，，8： | 5 |
| 10 | 椎动脉狭窄的诊断与治疗显示文摘大约1/4的缺血性卒中累及后循环或椎基底循环。椎动脉狭窄可发生在颅外段或颅内段,占后循环缺血性卒中的20%。狭窄性病变,特别是椎动脉起始部的狭窄性病变并不少见。在一项4748例缺血性卒中患者的血管造影研究中,18%的患者右侧、22.3%的患者左侧存在椎动脉颅外段近端不同程度的狭窄,仅次于颈动脉分又处的颈内动脉(ICA)狭窄而成为第2个常见的狭窄部位。采用血管内技术,目前已能够对上述狭窄进行治疗。 | GC Cloud HS Markus 苏克江(译) 赵莉莉(译) 蔡高云(译) 王桂敏(译) | 2005 | 中华脑血管病论坛2005，3，2： | 5 |
| 11 | Improvedendoscopicretrogradecholangiopancreatographybrushincreases diagnosticyieldofmalignantbiliarystrictures显示文摘AIM: To determine if a new brush design could im-prove the diagnostic yield of biliary stricture brushings. METHODS: Retrospective chart review was performed of all endoscopic retrograde cholangiopancreatography procedures with malignant biliary stricture brushing between January 2008 and October 2012. A standard wire-guided cytology brush was used prior to proto-col implementation in July 2011, after which, a new 9 French wire-guided cytology brush(Infinity sampling device, US Endoscopy, Mentor, OH) was used for all cases. All specimens were reviewed by blinded pa-thologists who determined whether the sample waspositive or negative for malignancy. Cellular yield was quantified by describing the number of cell clusters seen. RESULTS: Thirty-two new brush cases were compared to 46 historical controls. Twenty-five of 32 (78%) cases in the new brush group showed abnormal cellular find-ings consistent with malignancy as compared to 17 of 46(37%) in the historical control group(P = 0.0003). There was also a significant increase in the average number of cell clusters of all sizes(21.1 vs 9.9 clusters, P = 0.0007) in the new brush group compared to his-torical controls. CONCLUSION: The use of a new brush design for brush cytology of biliary strictures shows increased di-agnostic accuracy, likely due to improved cellular yield, as evidenced by an increase in number of cellular clus-ters obtained. | Shieh FK Luong-Player A Khara HS Liu H Lin F Shellenberger MJ Johal AS Diehl DL | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 4 |
| 12 | 白花蛇舌草和半枝莲增强巨噬细胞吞噬活性的研究显示文摘白花蛇舌草(Oldenlandia diffusa,简称 OD)系茜草科耳草属植物;半枝莲(Scutellaria barbara 简称 SB)系唇形科黄芩属植物,均全草入药。中医用以治疗肝、肺、及胃肠道肿瘤。有一定效果)。动物实验也证明它们有显著抑制鼠肾细胞癌生长及化学防癌变作用。我们用细胞培养法研究了 OD 和 SB 对小鼠 J774巨噬细胞吞噬活性的影响。现将实验结果报告于下。 | 贾泰元 Benjamin HS Lau | 1998 | 中国中西医结合杂志1998，18，S1： | 4 |
| 13 | Surface-active agent in Eustachian tube function显示文摘 | Rapport PN Lim DJ Weiss HS | 1975 | Arch Otolarygol1975，101，5： | 4 |
| 14 | Correlation and prognostic significance of beta-galactoside alpha-2,6-sialyltransferase and serum monosialylated alpha-fetoprotein in hepatocellular carcinoma显示文摘AIM: To investigate the correlation between tissue ST6Gal I and serum msAFP in HCC patients, and to investigate their prognostic significance.METHODS: Preoperative sera,paired tumorous and non-tumorous tissues were collected from 19 consecutive patients who had undergone surgical resection of HCC.ST6Gal T activities in the tissues were measured by an in vitro microsomal enzyme activity assay. The percentages of tumor-specific msAFP in the sera were also estimated by an isoelectric focusing-immunoblotting assay.RESULTS: The tumor ST6Gal I activity was negatively correlated with serum msAFP percentage (r = -0.53,P = 0.019). Both decreased tumor ST6Gal I activity andincreased serum msAFP percentage were associatedwith poor tumor cell differentiation. Univariate analyses showed that both decreased tumor ST6Gal T activity (P = 0.028), increased serum msAFP percentage (P = 0.034) and poor tumor cell differentiation (P = 0.031)were associated with shorter overall survival. Multivariate analysis using the Cox regression model showed that the preoperative serum msAFP percentage (P = 0.022)and tumor cell differentiation status (P = 0.048) were independent prognostic indicators for patient overall survival.CONCLUSION: Our results indicate that the presence of msAFP in blood circulation is associated with a decreased activity of ST6Gal I activity in HCC. Both tissue ST6Gal I and serum msAFP are potential prognostic markers for patients with operable HCC. | Terence CW Poon Clarissa HS Chiu Paul BS Lai Tony SK Mok Benny Zee Anthony TC Chan Joseph JY Sung Philip J Johnson | 2005 | World Journal of Gastroenterology2005，11，42： | 4 |
| 15 | TLR-3启动子区功能性基因多态性与骨关节炎的相关性:两阶段病例对照研究显示文摘骨关节炎(osteoarthritis,OA)被认为是多因素疾病,目前有关其遗传因素的研究涉及了遗传方式及基因组的潜在突变位置等。最近的报道显示,Toll样受体(toll-like receptor,TLR)家族与OA的发生发展关系密切。单核苷酸多态性(single nucleotide polymorphisms,SNPs)在TLR基因中普遍存在,并对TLR功能产生影响。前期研究证实,TLR-9基因的(-1486T/C)启动子多态性与末期膝OA有关,而作为同属于核内体TLR、均以病原相关分子方式来识别病毒和细菌核酸的TLR-3,7,8,其功能性基因多态性是否与中国汉族人群膝OA有关,是本研究的主要目的。 | Yang HY Lee HS Lee CH 白朝晖 章莹 | 2013 | 中国骨科临床与基础研究杂志2013，5，6： | 3 |
| 16 | P-wave velocities of alkaline olivine basalt at high pressure and temperature and its controlling factors显示文摘SEISMIC wave inversion is one of the most important means for us to recognize the compositionand structure of the Earth’s interior.Although the experimental techniques of elastic wave ve-locity measurement at in situ high pressure and temperature develop very fast in recent | Song, MS Xie, HS Zhang, YM Hou, W Xu, J Xu, YS | 1997 | Chinese Science Bulletin1997，42，9： | 3 |
| 17 | 欧洲胃肠内镜学会和美国胃肠内镜学会指南预测胆囊切除术患者可疑胆总管结石的临床效果显示文摘【据《Endoscopy》2020年2月在线报道】题:欧洲胃肠内镜学会和美国胃肠内镜学会指南预测胆囊切除术患者可疑胆总管结石的临床效果(作者Jagtap N等)最新版欧洲胃肠内镜学会(ESGE)和美国胃肠内镜学会(ASGE)指南推荐要根据肝功能和腹部超声检查对可疑胆总管结石患者进行风险分层。来自印度海得拉巴亚洲胃肠病研究所的Jagtap等进行了一项研究,评估和验证了ESGE和ASGE新的风险分层标准预测胆总管结石的临床效用。 | 李家速 刘枫 JAGTAP N YASHAVANTH HS TANDAN M | 2020 | 临床肝胆病杂志2020，36，5： | 3 |
| 18 | 青年人群腰椎骨密度及标准差对骨质疏松检出率的影响:多中心、大样本分析(英文)显示文摘背景:不同地区骨峰值和标准差不同,对骨质疏松诊断率有较大影响。探讨建立一完整数据库为中国人骨质疏松诊断准确性提供依据。目的:探讨青年人腰椎骨密度和标准差正常参考值影响骨质疏松症检出率的程度。设计、时间及地点:调查分析,于1997-01/1999-12分别在北京、上海、广州、南京、嘉兴和成都市完成。对象:采用前瞻性及回顾性方法对全国6个中心骨密度参考数据库中11418人进行调查统计分析;男3666人,女7752人;年龄20岁~90岁;分别来自北京(2385人)、广州(1178人)、上海(1404人)、南京(2938人)、成都(1425人)、嘉兴(2088人),受试者来源于社区调查、健康体检和健康志愿者。方法:用GE-Lunar公司的DXA仪测量骨密度,调查全国6个中心11418人L2~L4腰椎后前位和髋部骨密度,建立了骨密度参考数据库。6个中心的仪器内部精度0.3%~0.7%,仪器间的精度1.1%。主要观察指标:①6个中心不同年龄组腰椎骨密度分布。②青年人群骨密度及其标准差值对骨质疏松症检出率的影响。结果:中国汉族女性以腰椎进行骨质疏松症诊断的青年人群的骨密度和标准差值,6个中心,最大差值分别为0.098g/cm2和0.027g/cm2。用6个中心及总体各自的青年人平均骨密度和标准差值为参考标准,对同一人群计算T-score和获得的骨质疏松症检出率不相同;发现青年人平均骨密度每变化0.01g/cm2,则骨质疏松症检出率变化1.6%(呈正相关),其标准差值每变化0.01g/cm2,则骨质疏松症检出率变化4%(呈负相关)。结论:青年人平均骨密度和标准差值不同引起骨质疏松症检出率也不相同。为了让不同中心的骨质疏松症检出率有可比性,建议同一个类型的骨密度仪,同一个种族,同一个地区用一个设计较完善大样本的参考数据库,以其青年人正常参考值计算T-score。 | 王文志 杨定焯 蒋建军 吴涛 程晓光 周琦 卓铁军 张华俦 项静 王洪复 区品中 刘建立 徐苓 黄公怡 黄琪仁 HS Barden LS Weynand KG Fqukner 孟迅吾 | 2008 | 中国组织工程研究与临床康复2008，12，50： | 3 |
| 19 | 抗生素作为严重急性营养不良治疗的一部分显示文摘背景:严重急性营养不良每年导致100万儿童死亡。营养治疗中常规加入抗生素可能提高社区中治疗的严重急性营养不良儿童的恢复率,并降低死亡率。 | Trehan I Goldbach HS LaGrone LN 柏振江 汪健 | 2013 | 中华实用儿科临床杂志2013，28，11： | 3 |
| 20 | 双通偏振干涉滤光片的研究显示文摘研究了等厚度双通偏振干涉滤光片 ,在此基础上提出了新型双通偏振干涉滤光片 ,并分析了单通、双通以及新型双通偏振干涉滤光片的光谱特性。结果表明 ,新型双通偏振干涉滤光片不仅具有更好的光谱特性 ,而且能进一步减少延迟片数目 ,具有非常重要的实用价值 ,可望在基于硅片的液晶投影仪分 /合色系统中得到广泛应用。 | 贺银波 熊静懿 吴国忠 郑伟 曾广杰 余飞鸿 HS Kwok | 2003 | 光学学报2003，23，1： | 3 |
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