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| 1 | Iatrogenic esophago-tracheal fistula:Challenges in diagnosis and management显示文摘Esophageo-tracheal fistula is a rare condition,and in most cases such fistulas are caused by malignant disease or emergency endotracheal intubation.A case where a wrapped tablet produced a fistula between the esophagus and trachea is described.The patient is a male born in 1938 who swallowed a tablet without unwrapping it.The patient was treated with selfexpanding metal stents(SEMS),but closure of the fistula was not achieved.Different examinations and treatment options are discussed.Surgical treatment for this condition has demonstrated considerable mortality and morbidity.In some cases closure of the fistula can be achieved by use of SEMS.Although we advise treatment of such cases with SEMS,in some cases treatment with stents will prove troublesome and the risk/benefit analysis will have to be reevaluated. | istein Hovde yvind Haugen Lie Per Arthur Johansson ystein Stubhaug Egil Johnson Bjrn Hofstad Truls Hauge | 2013 | World Journal of Gastroenterology2013，19，4： | 5 |
| 2 | Epidemiology and clinical course of Crohn's disease:Results from observational studies显示文摘The authors review the clinical outcome in patients with Crohn's disease(CD)based on studies describing the natural course of the disease.Population-based studies have demonstrated that the incidence rates and prevalence rates for CD have increased since the mid-1970s.The authors search for English language articles from 1980 until 2011.Geographical variations,incidence,prevalence,smoking habits,sex,mortality and medications are investigated.An increasing incidence and prevalence of CD have been found over the last three decades.The disease seems to be most common in northern Europe and North America,but is probably increasing also in Asia and Africa.Smoking is associated with an increased risk of developing CD.Age <40 at diagnosis,penetrating/stricturing complications,need for systemic steroids,and disease location in terminal ileum are factors associated with higher relapse rates.A slight predominance of women diagnosed with CD has been found.Ileocecal resection is the most commonly performed surgical procedure,and within the first five years after the diagnosis about one third of the patients have had intestinal surgery.Smoking is associated with a worse clinical course and withincreased risk of flare-ups.In most studies the overall mortality is comparable to the background population.To date,the most effective treatment options in acute flares are glucocorticosteroids and tumor necrosis factor(TNF)-α-blockers.Azathioprine/methotrexate and TNF-α-blockers are effective in maintaining remission. | istein Hovde Bjrn A Moum | 2012 | World Journal of Gastroenterology2012，18，15： | 4 |
| 3 | Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients显示文摘AIM To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease(IBD).METHODS IBD patients were recruited from nine hospitals in the southeastern and western regions of Norway to participate in a multicenter cross-sectional study lasting from March 2013 to April 2014. Data were collected by interviews, from medical records and laboratory tests. The Fatigue Questionnaire(FQ) was used to measure fatigue. Linear and logistic regression models were applied to explore the possible association between vitamin D deficiency and total fatigue scores and chronic fatigue, respectively. The analyses were adjusted for age, gender, disease activity, depressive symptoms and sleep disturbance.RESULTS In total, 405 patients were included in the analyses, of which 227(56%) had Crohn's disease(CD) and 178(44%) had ulcerative colitis(UC). Vitamin D deficiency(< 50 nmol/L) was present in half(203/405) of the patients. Chronic fatigue was reported by 116(29%) of all included patients with substantial fatigue reported by 194(48%). Vitamin D levels were neither associated with total fatigue nor with chronic fatigue. Higher total fatigue scores and chronic fatigue were both associated with increased disease activity scores in patients with UC and CD, but not with increased CRP or fecal calprotectin. In UC patients, female gender was associated with fatigue in the univariate analysis, but no such difference was found when adjusted for elevated disease activity scores. Sleep disturbance and more depressive symptoms were associated with total fatigue scores in both UC and CD patients, but with chronic fatigue only in CD patients.CONCLUSION In this study, no significant association between fatigue and vitamin D deficiency in IBD patients was revealed. | Svein Oskar Frigstad Marte Lie Hoivik Jorgen Jahnsen Milada Cvancarova Tore Grimstad Ingrid Prytz Berset Gert Huppertz-Hauss Oistein Hovde Tomm Bernklev Bjorn Moum Lars-Petter Jelsness-Jorgensen | 2018 | World Journal of Gastroenterology2018，24，29： | 2 |
| 4 | Decomposition principle in model predictive control for linear s:lstems with bounded disturb-ances 显示文摘 | SUI D FENG L HOVD M | 2009 | Automatica2009，45，8： | 1 |
| 5 | Decomposition principle in model predictive control for linear systems with bounded disturbances显示文摘 | SUI D FENG L HOVD M | 2009 | Automatica2009，45，8： | 1 |
| 6 | Control of symmetrically interconnected plants 显示文摘 | Hovd M Skogestad S | 1994 | Automatica1994，，6： | 1 |
| 7 | Decomposition principle in model predictive control for linear systems with bounded disturb- ances 显示文摘 | SUI D FENG L HOVD M | 2009 | Automatica2009，45，8： | 1 |
| 8 | Mutant prevention concentrations of ABT-492,levofloxacin,moxifloxacin,and gatifloxacin against three common respiratory pathogens显示文摘 | HERMSEN E D HOVDE L B KONSTANTINIDES G N | 2005 | Antimicrob Agents Chemother2005，49，4： | 1 |
| 9 | Control of symmetrically interconnected plants 显示文摘 | SKOGESTAD S | 1994 | Automatica1994，30，6： | 1 |
| 10 | Synergistic activity of colistin and ceftazidime against multiantibioticresistant Pseudomonas aeruginosa in an in vitro pharmacodynamic model显示文摘 | Gunderson B W Ibrahim K H Hovde L B | 2003 | Antimicrob Agents Chemother2003，47，3： | 1 |
| 11 | Locality properties of radial basis function expansion coefficients for equispaced inter- polation 显示文摘 | Fornberg B Flyer N Hovde S | 2008 | IMA Journal of Numerical Analysis2008，28，1： | 1 |
| 12 | Investigation of the role of the disulphide bond in the activity and structure of staphylococcal enterotoxin C显示文摘 | HOVDE C J MARR J C HOFFMANN M L | 1994 | Molecular Microbiology1994，13，： | 1 |
| 13 | Improved independent design of robust decentralized controllers显示文摘 | Hovd M Skogestad S | 1993 | Journal of Process Control1993，3，1： | 1 |
| 14 | Control of Symmetrically Interconnected Plants显示文摘 | Hovd M Skogestad S | 1994 | Automatica1994，30，： | 1 |
| 15 | Spatial, seasonal and ontogenetic variation in diet of Northeast Arctic Greenland halibut (Reinhardtius hippoglossoides) 显示文摘 | Hovde S C Albert O T Nilssen E M | 2002 | ICES J Mar Sci2002，59，： | 1 |
| 16 | Acute bacterial conjunctivitis 显示文摘 | Hovding G | 2008 | Acta Ophthalmol2008，85，1： | 1 |
| 17 | The Escherichia coli O157 flagellar regulatory gene flhC and not the flagellin gene fliC impacts colonization of cattle显示文摘 | DOBBIN H S HOVDE C J WILLIAMS C J | 2006 | Infection and Immunity2006，74，5： | 1 |
| 18 | Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I 显示文摘 | Calderwood SB Mekalanos JJ | 1988 | Proc Natl Acad Sci USA1988，85，： | 1 |
| 19 | Fluoro-quinolone resist-ance in Bacteroides fragilis following sparfloxacin exposure显示文摘 | Peterson ML Hovde LB Wright DH | 1999 | Anti-micTob Agents Chemother1999，43，9： | 1 |
| 20 | Fluoroquinolone resistance in bacteroides fragilis following sparfloxacin exposure 显示文摘 | Peterson ML Hovde LB Wright DH | 1999 | Antimicrob Agents Chemother1999，43，9： | 1 |
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