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| 1 | 23G玻璃体视网膜手术治疗孔源性视网膜脱离(英文)显示文摘目的:报告23G玻璃体视网膜手术治疗孔源性视网膜脱离(rhegmatogenous retinal detachment,RRD)的有效性和安全性。方法:本回顾性研究中,49例49眼RRD患者于2007-01/2009-07在我院行23G经巩膜无缝线玻璃体切除术纳入研究。结果:平均随访时间8.9±7.7mo(1~28mo)。47眼(95.9%)视网膜再次脱离经一次手术治愈,2眼因新出现裂孔的视网膜再次脱离通过23G经巩膜无缝线玻璃体切除术治愈。术前平均logMAR视力2.01±0.47,术后1.3±0.5(P<0.001,Paired t-test)。术前平均眼压(intraocularpressure,IOP)14.1±2.8mmHg,术后1d平均眼压12.3±3.6mmHg,术后1wk平均眼压13.1±2.1mmHg,术后1mo平均眼压14.3±2.2mmHg。术中医源性周边视网膜裂孔1眼(2.0%)。巩膜或结膜切口不要求缝合,无1眼需要转换为20G玻璃体切除术。结论:23G经巩膜无缝线玻璃体切除术可以有效,安全的治疗RRD。 | Ates Yanyali Gokhan Celik Alper Dincyildiz Fatih Horozoglu Ahmet F. Nohutcu | 2012 | 国际眼科杂志2012,12,7: | 4 |
| 2 | Primary 23-gauge vitreoretinal surgery for rhegmatogenous retinal detachment显示文摘AIM: To report the effectiveness and safety of primary 23-Gauge (G) vitreoretinal surgery for rhegmatogenous retinal detachment (RRD). · METHODS: In this retrospective study, 49 eyes of 49 consecutive patients who underwent primary 23-G transconjunctival sutureless vitrectomy (TSV) for RRD between January 2007 and July 2009 at our institution were evaluated. · RESULTS: Mean follow-up time was 8.9±7.7 months (1-28 months). Retinal reattachment was achieved with a single operation in 47(95.9%) of 49 eyes. In two eyes (4.1%), retinal redetachment due to new breaks was successfully treated with reoperation using the 23-G TSV system. Mean logMAR visual acuity was 2.01±0.47 preoperatively and 1.3±0.5 postoperatively (P <0.001, Paired t -test). Mean preoperative intraocular pressure (IOP) was 14.1±2.8mmHg. Mean postoperative IOP was 12.3±3.6mmHg at 1 day, 13.1±2.1mmHg at 1 week, 14.3±2.2mmHg at 1 month. Iatrogenic peripheral retinal break was observed in 1 eye(2.0%) intraoperatively. No sutures were required to close the scleral or conjunctival openings, and no eyes required convertion of surgery to 20-G vitrectomy. · CONCLUSION: Primary 23-G TSV system was observed to be effective and safe in the treatment of RRD. | Ates Yanyali Gokhan Celik Alper Dincyildiz Fatih Horozoglu Ahmet F. Nohutcu | 2012 | International Journal of Ophthalmology(English edition)2012,5,2: | 3 |
| 3 | 阿柏西普治疗雷珠单抗效果不佳的CNV伴难治性色素上皮脱离的疗效(英文)显示文摘目的:评估雷珠单抗反应欠佳患者治疗早期转为阿柏西普治疗疗效。方法:该研究包括38例湿性年龄相关性黄斑变性(W-AMD)患者。18例反应欠佳患者改用玻璃体内阿柏西普(IVA)每月3次疗法,其余20例反应欠佳患者持续进行玻璃体内雷珠单抗(IVR)治疗,每月增加3次使用。所有改变均行荧光素血管造影术(FA)和光学相干断层扫描成像术(OCT)评估。结果:患者术前平均视力(VA)和黄斑中心厚度(CMT)分别为0.84±0.47 logM AR和360±84μm。经过6次IVR或3次IVR联合3次IVA治疗1mo后,两组患者视力分别为1.1±0.14(P=0.11)logM AR和0.48±0.37(P=0.019)logM AR,黄斑中心厚度分别为300±79μm(P=0.002)和271±51μm(P=0.002)。结论:对于雷珠单抗治疗反应欠佳患者,减少重复性治疗早期转为使用阿柏西普疗法对于视力康复是更好的选择。 | Sever Ozkan Horozoglu Fatih | 2017 | 国际眼科杂志2017,17,10: | 2 |
| 4 | Macular thickness changes after phacoemulsification in previously vitrectomized eyes for diabetic macular edema 显示文摘 | Horozoglu F Yanyali A Aytug B | 2011 | Retina2011,31,6: | 1 |
| 5 | Corneal topographic changes after transconjunctival (25-gauge) sutureless vitrectomy显示文摘 | Yanyali A Celik E Horozoglu F Nohutcu AF | | 0,,05: | 1 |
| 6 | Pars plana vitreetomy and removal of the internal limiting membrane in diabetic macular edema unresponsive to grid laser photocoagulatinn显示文摘 | Yanyali A horozoglu E celik Y e! al | 2006 | Eur Journalof Ophthalmology2006,16,: | 1 |
| 7 | Bevacizumab(Avastin)fordiabetic macular edema in previously vitrectomized eyes 显示文摘 | Yanyali A Aytug B Horozoglu F | 2007 | Oph-thalmology2007,144,1: | 1 |
| 8 | 25-Gauge transconjunctival sutureless pars plana vitrectomy显示文摘 | Yanyali A Celik E Horozoglu F Oner S Nohutcu AF | | 0,,01: | 1 |
| 9 | Modified grid laser photocoagulation versus pars plana vitrectomy with internal limiting membrane removal in diabetic macular edema显示文摘 | Yanyali A Nohutcu AF Horozoglu F | | 0,,: | 1 |
| 10 | Modified grid laser photocoa-gulation versus pars plana vitrectomy with internal limiting membrane removal in diabetic macular edema显示文摘 | Yanyali A Nohutcu A F Horozoglu F | 2005 | Am J Ophthalmol2005,62,139: | 1 |
| 11 | Long-term outcomes of pars plana vitrectomy with internal limiting membrane removal in diabetic macular edema显示文摘 | Yanyali A Horozoglu F Celik E | | 0,,: | 1 |
| 12 | Primary 25-gauge transconjunctival sutureless vitrectomy in pseudophakic retinal detachment显示文摘 | Horozoglu F Yanyali A Celik E Aytug B Nohutcu AF | | 0,,05: | 1 |
| 13 | Modified grid laser photocoagulation versus pars plan vitrectomy with lim- iting internal mem-brane removal in diabetic macular edema显示文摘 | Yanyali A Nohutcu AF Horozoglu F | 2005 | Am J Ophthalmol2005,139,6: | 1 |
| 14 | Bevacizumab (Avastin) for diabetic macular edema in previously vit- rectomized eyes显示文摘 | Yanyali A Aytug B Horozoglu F | 2007 | Am J Ophthalmol2007,144,1: | 1 |
| 15 | Long-term outcomes of pars plana vitrectomy with internal limiting membrane removal in diabetic macular edema显示文摘 | Yanyali A Horozoglu F Celik E | 2007 | Retina2007,27,5: | 1 |
| 16 | Corneal Topographic Changes After Transconjunctival (25-gauge) Sutureless Vitrectomy显示文摘 | Ates Yanyali Erkan Celik Fatih Horozoglu Ahmet F. Nohutcu | 2005 | American Journal of Ophthalmology2005,,5: | 1 |
| 17 | Long-term outcomes of pars planavitrectomy with internal limiting membrane removal in diabetic macularedema显示文摘 | Yanyali A Horozoglu F Celik E | 2007 | Retina2007,27,: | 1 |
| 18 | 25-Gauge transcon- junctival sutureless pars plana vitrectomy显示文摘 | Yanyali A Celik E Horozoglu F | 2006 | Eur J Oph- thalmol2006,16,1: | 1 |
| 19 | 贝伐单抗单用与联合曲安奈德治疗糖尿病性黄斑水肿的疗效比较(英文)显示文摘目的:比较单用贝伐单抗与贝伐单抗联合曲安奈德治疗糖尿病黄斑水肿疗效。方法:回顾性比较随机研究。对21例42眼黄斑水肿的糖尿病患者进行了评估。单眼内注射1. 25 mg贝伐单抗(IVB组),在同组的眼玻璃体内注射1. 25 mg贝伐单抗和1 mg曲安奈德(IVTA-IVB组)。使用光学相干断层扫描(OCT)、ETDRS视力和眼压测量黄斑中心厚度(CMT)。结果:平均随访时间为4. 7±1. 5mo。在IVB组和IVTAIVB组中,注射前平均CMT分别为494. 7±114. 4μm,546. 8±165. 6μm;第一个月分别为430. 4±133. 2μm,363. 7±105. 3μm;第三个月分别为484. 8±167. 4μm,407. 3±108. 7μm;六个月后分别为550. 4±191. 5μm,516. 8±158μm。第一个月和第三个月存在显著差异(P <0. 05)。在IVB组和IVTA-IVB组中,注射前平均ETDRS视力数分别为57. 1±13. 5,48. 9±13. 9;第一个月分别为2. 2±14,58. 8±12. 1;第三个月分别为59±13. 7,59. 3±13. 6;第六个月分别为55. 6±14. 9,55. 5±8. 7。第三个月和第六个月存在显著差异(P<0. 05)。IOP无差异。第一次注射后IVTA-IVB组在第三个月时视力最佳并持续6个月,而IVB组在第一个月时视力最佳但仅持续了3个月。结论:6个月后发现,IVTA-IVB组较IVB组疗效显著,且无激素依赖性并发症。 | Sever Ozkan Horozoglu Fatih Celik Erkan Topcu Birol | 2019 | 国际眼科杂志2019,19,1: | 1 |
| 20 | Association of SUMO4 M55V and-94ins/del gene variants with type-2diabetes显示文摘 | Sozen S Horozoglu C Bireller ES | 2014 | In Vivo2014,28,5: | 1 |