|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 液体过负荷,基础疾病及启动时机对接受连续性肾脏替代治疗危重症患儿的影响显示文摘目的:确定需要连续性肾脏替代(continuous renal replacement therapy,CRRT)治疗危重症患儿病死因素。设计基于前瞻性注册登记的回顾性观察性研究。场所拥有30张床位的三级、四级转诊PICU。对象接受CRRT的危重症患儿。干预连续性肾脏替代治疗。测量方法与主要结果研究期间接受CRRT治疗的161例患儿总体病死率为36%(n=58),接受体外膜肺氧合(extracorporeal membrane oxygenation,ECMO)治疗患儿病死率为47.5%(28/59),显着高于无需ECMO治疗者[28.4%(29/102),P=0.022]。根据入院诊断,血液肿瘤患儿病死率最高(77.8%),肾脏病患儿则最低(5.6%)。基于多元Logistic回归分析,入院时疾病严重程度评分较高(校正OR 1.49,95%CI 1.18~1.89,P<0.001),血液肿瘤疾病(OR 17.10,95%CI 4.10~72.17,P<0.001),液体过负荷10%~20%(OR 3.83,95%CI 1.33~11.07,P=0.013),>20%(OR 15.03,95%CI 4.03~56.05, P<0.001),及CRRT启动时机(OR 1.01,95%CI 1.00~1.01,P=0.040)与病死率独立相关。本研究人群中,从入住ICU起CRRT启动每延迟1 h,死亡几率增加1%。结论CRRT患儿病死率高,且与基础疾病,疾病严重程度和液体过负荷程度相关。在急性肾损伤及液体过负荷风险较高的危重症患儿中,早期启动CRRT可能降低病死率。 | Cortina G McRae R Hoq M 方伯梁(译者) 钱素云(审校者) | 2019 | 中国小儿急救医学2019，26，4： | 10 |
| 2 | Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity显示文摘Even with implementation of current influenza vaccines,influenza still claims up to 500,000 lives worldwide annually,indicating a need for a better vaccine strategy.We have developed a technology to generate unique S_(60)-HA1 pseudovirus nanoparticles(PVNPs)that display the receptor-binding HA1 domains of influenza viruses.Each self-assembled S_(60)-HA1 PVNP consists of a T=1 icosahedral S_(60) nanoparticle that resembles the inner shell of norovirus capsid and 60 surface-displayed HA1 antigens that are excellent vaccine targets.Soluble S_(60)-HA1 PVNPs presenting HA1 antigens of H7N9 influenza virus subtypes have been produced efficiently in large amount.Their three-dimensional(3D)structures have been solved by cryogenic electron microscopy.The PVNP-displayed HA1 antigens react with HA-specific antibody,and retain authentic sialic acid binding specificity and hemagglutinate human erythrocytes.The PVNPs are highly immunogenic,eliciting high titers of HA1-specific antibodies in mice and the mouse sera strongly inhibited hemagglutinations of homologous and heterologous influenza virus HA proteins.Therefore,the S_(60)-HA1 PVNPs may provide useful reagents to study influenza viruses and offer a potential new vaccine tactic to fight the deadly influenza disease. | Ming Xia Md Rejaul Hoq Pengwei Huang Wen Jiang Xi Jiang Ming Tan | 2022 | Nano Research2022，15，5： | 2 |
| 3 | Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span显示文摘 | Azziz R Marin C Hoq L | 2005 | Clin Endocrinol Metab2005，90，1： | 1 |
| 4 | Health care related economic burden of the polycystic ovary syndrome during the reproductive life span显示文摘 | AZZIZ R MARIN C HOQ L | 2009 | J Clin Endocrinol Metab2009，90，8： | 1 |
| 5 | Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding显示文摘 | IBRAHIM H R HOQ M I AOKI T | 2007 | Int J Biol Macromol2007，41，5： | 1 |
| 6 | Health care-related economic burdenof the polycystic ovary syndrome during the reproductive life span显示文摘 | Azziz R Marin C Hoq L | 2005 | J Clin Endocrinol Metab2005，90，8： | 1 |
| 7 | Tako tsubo cardiomyopathy ( transient left ventricular apical ballooning) : case report of a myocardial perfusion echocardiogram study 显示文摘 | Upadya SP Hoq SM Pannala R | 2005 | J Am Soc Echocardiogr2005，18，3： | 1 |
| 8 | Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding显示文摘 | Hisham R Ibrahim Md Imranul Hoq Takayoshi Aoki | 2007 | International Journal of Biological Macromolecules2007，41，： | 1 |
| 9 | Healthcare-relatedeconom-icburden of the polycystic ovary syndrome (PCOS)duringthereproductivelifespan显示文摘 | Azziz R Marin C Hoq L | 2005 | J Clin Endocrinol Metab2005，90，46： | 1 |
| 10 | Economic burden of the polycystic ovary syndrome (PCOS) during the reproductive lifespan 显示文摘 | Azziz R Matin C Hoq L | 2005 | Clin Endocrinol Metab2005，90，： | 1 |
| 11 | Mechanistic studies of hydrocarbon CH/D2 exchange over thermally activated magnesium oxide显示文摘 | Hoq Fazlul M Klabunde K J | 1990 | Journal of Catalysis1990，123，2： | 1 |
| 12 | Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding显示文摘 | Hisham R Ibrahim Md Imranul Hoq Takayosbi Aoki | 2007 | International Journal of Biological Macromolecules2007，41，： | 1 |
| 13 | Health care-related economicburden of the polycystic ovary syndrome during the reproductive lifespan显示文摘 | Azziz R Marin C Hoq L | 2005 | Clin Endocrinol Metab2005，90，1： | 1 |
| 14 | Isolation and characterization of antibacterial peptides from the mud-crab, Scylla serrata 显示文摘 | HOQ M I SERAJ M U CHOWDHURY S | 2003 | Pakistan Journal of Bio- logical Sciences2003，6，15： | 1 |
| 15 | Healthcare-related economic burden of the polycystic ovary syndrome (PCOS) during the reproductive lifespan显示文摘 | Azziz R Marin C Hoq L | 2005 | J Clin Endocrinol Metab2005，90，8： | 1 |
| 16 | Continuous hydrolysis of olive oil by lipase in microporous hydrophobic membrane bioreactor 显示文摘 | HOQ M M YAMANE T SHIMIZU S | 1985 | J AM Oil Chem Soe1985，62，6： | 1 |
| 17 | Continuous hydrolysis of olive oil by lipase in microporous hydrophobic membrane 显示文摘 | Hoq M M Yamane T Shimizu S | 1985 | J Am Oil Chem Soc1985，62，： | 1 |
| 18 | , Hydrographic status of Sundarbans mangrove, Bangladesh with special reference to post-larvae and juveniles fish and shrimp abundance显示文摘 | Enamul Hoq M Abdul Wahab M and Nazrul Islam M | 2006 | Wetlands Ecology and Management2006，14，： | 1 |
| 19 | l Health care - related economic burden of the polycystic ovary syndrome during the reproductive life span显示文摘 | Azziz R Marin C Hoq L eta | 2005 | J Clin Endocrinol Metab2005，90，8： | 1 |
| 20 | Health care-related economic burden of the polycystie ovary syndrome during the reproductive life span显示文摘 | Azziz R Marin C Hoq L | 2005 | Clin Endocrinol Metab2005，90，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员