|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Precise orbit determination of Beidou Satellites with precise positioning显示文摘Chinese Beidou satellite navigation system constellation currently consists of eight Beidou satellites and can provide preliminary service of navigation and positioning in the Asia-Pacific Region.Based on the self-developed software Position And Navigation Data Analysis(PANDA) and Beidou Experimental Tracking Stations (BETS),which are built by Wuhan University,the study of Beidou precise orbit determination,static precise point positioning (PPP),and high precision relative positioning,and differential positioning are carried out comprehensively.Results show that the radial precision of the Beidou satellite orbit determination is better than 10 centimeters.The RMS of static PPP can reach several centimeters to even millimeters for baseline relative positioning.The precision of kinematic pseudo-range differential positioning and RTK mode positioning are 2-4 m and 5-10 cm respectively,which are close to the level of GPS precise positioning.Research in this paper verifies that,with support of ground reference station network,Beidou satellite navigation system can provide precise positioning from several decimeters to meters in the wide area and several centimeters in the regional area.These promising results would be helpful for the implementation and applications of Beidou satellite navigation system. | SHI Chuang ZHAO QiLe LI Min TANG WeiMing HU ZhiGang LOU YiDong ZHANG HongPing NIU XiaoJi LIU JingNan | 2012 | Science China Earth Sciences2012，55，7： | 61 |
| 2 | Global modeling 2^(nd)-order ionospheric delay and its effects on GNSS precise positioning显示文摘Ionospheric delay is one of the major error sources in GNSS navigation and positioning.Nowadays,the dual-frequency technique is the most widely used in ionospheric refraction correction.However,dual-frequency measurements can only eliminate the first-order term of ionospheric delay,while the effect of the second-order term on GNSS observations may be several centimeters.In this paper,two models,the International Reference Ionosphere (IRI) 2007 and International Geomagnetic Reference Field (IGRF) 11 are used to estimate the second-order term through the integral calculation method.Besides,the simplified single layer ionosphere model in a dipole moment approximation for the earth magnetic field is used.Since the traditional integral calculation method requires large calculation load and takes much time,it is not convenient for practical use.Additionally,although the simplified single layer ionosphere model is simple to implement,it results in larger errors.In this study,second-order term ionospheric correction formula proposed by Hoque (2007) is improved for estimating the second-order term at a global scale.Thus,it is more practicable to estimate the second-order term.More importantly,its results have a higher precision of the sub-millimeter level for a global scale in normal conditions.Compared with Hoque's original regional correction model,which calculates coefficients through polynomial fitting of elevation and latitudes,this study proposes a piece-wise look-up table and interpolation technique to modify Hoque model.Through utilizing a table file,the modified Hoque model can be conveniently implemented in an engineering software package,like as PANDA in this study.Through applying the proposed scheme for the second-order ionospheric correction into GNSS precise positioning in both PPP daily and epoch solutions,the results have shown south-shift characteristics in daily solution at a global scale and periodic change with VTEC daily variation in epoch positioning solution. | ZHANG HongPing LV HaiXia LI Min SHI Chuang | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，6： | 5 |
| 3 | SDS-PAGE study on photooxidation damage of lysozyme induced by riboflavin显示文摘The photooxidation damage of lysozyme under 315-375 nm irradiation in the presence of riboflavin was studied by using sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE).Indica- tions showed that the mechanisms and products of oxidative damage were relative to the concentra- tion of riboflavin,the time of irradiation and the ambience.The type I process was examined in a nitrogen saturated solution,whereas both type I and type II were observed in an aerobic atmosphere and type II was the dominant process.The study also suggested that antioxidants,such as melatonin, can reduce the damage of lysozyme effectively. | ZHANG ZhaoXia ZHAO HongWei ZHU HongPing GE Min WANG WenFeng YAO SiDe LI WenXin | 2007 | Science China Chemistry2007，50，1： | 3 |
| 4 | Influence of Chromatogram Baseline Shifts and Exogenous Metabolite Signals on Metabolic Profiles of Traditional Chinese Medicine Chaihu and Its Liver Toxicity Metabonomics显示文摘 | ZENG Qi FENG Jiangjiang LU Tian XU Liangyu MIN Chunyan XIE Hongping | 2017 | Chemical Research in Chinese Universities2017，33，1： | 2 |
| 5 | Numerical Analysis of Three-Layer Deep Tunnel Composite Structure显示文摘To date,with the increasing attention of countries to urban drainage system,more and more regions around the world have begun to build water conveyance tunnels,sewage pressure deep tunnels and so on.However,the sufficient bearing capacity and corrosion resistance of the structure,which can ensure the actual service life and safety of the tunnel,remain to be further improved.Glass Fiber Reinforced Plastics(GFRP)pipe,with light weight,high strength and corrosion resistance,has the potential to be applied to the deep tunnel structure.This paper proposed a new composite structure of deep tunnel lined with GFRP pipe,which consisted of three layers of concrete segment,cement paste and GFRP pipe.A new pipe-soil spring element model was proposed for the pipesoil interaction with gaps.Based on the C3D8R solid model and the Combin39 spring model,the finite element numerical analysis of the internal pressure status and external pressure stability of the structure was carried out.Combined with the checking calculation of the theoretical formula,the reliability of the two finite element models was confirmed.A set of numerical analysis methods for the design and optimization of the three-layer structure was established.The results showed that from the internal GFRP pipe to the outer concrete pipe,the pressure decreased from 0.5 to 0.32 MPa,due to the internal pressure was mainly undertaken by the inner GFRP pipe.The allowable buckling pressure of GFRP pipe under the cover of 5 GPa high modulus cement paste was 2.66 MPa.The application of GFRP pipe not only improves the overall performance of the deep tunnel structure but also improves the construction quality and safety.The three-layer structure built in this work is safe and economical. | Weiwei Sun Hongping Min Jianzhong Chen Chao Ruan Yanjun Zhang Lei Wang | 2021 | Computer Modeling in Engineering & Sciences2021，，4： | 2 |
| 6 | Frontal polymerization preparation of poly ( acryl- amide - co - acrylic acid )/activated carbon com- posite hydrogels for dye removal 显示文摘 | Shengfang Li Hongping Huang Min Tao | 2013 | Journal of Applied Polymer Science2013，，3： | 1 |
| 7 | Carbohydrate Polymers 显示文摘 | DAI Jun WU Yan CHEN Shangwei ZHU Song YIN Hongping WANG Min TANG Jian | 2010 | S2:6292010，2，： | 1 |
| 8 | Schaftoside inhibits 3CL^(pro)and PL^(pro)of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19显示文摘It is an urgent demand worldwide to control the coronavirus disease 2019(COVID-19)pandemic caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virus.The 3-chymotrypsin-like protease(3CL^(pro))and papain-like protease(PL^(pro))are key targets to discover SARS-CoV-2 inhibitors.After screening 12 Chinese herbal medicines and 125 compounds from licorice,we found that a popular natural product schaftoside inhibited 3CL^(pro)and PL^(pro)with IC_(50)values of 1.73±0.22 and 3.91±0.19μmol/L,respectively,and inhibited SARS CoV-2 virus in Vero E6 cells with EC_(50)of 11.83±3. 23μmol/L. Hydrogen-deuterium exchange mass spectrometry analysis, quantum mechanics/molecular mechanics calculations, together with site-directed mutagenesis indicated the antiviral activities of schaftoside were related with non-covalent interactions with H41, G143 and R188 of3CLpro, and K157, E167 and A246 of PLpro. Moreover, proteomics analysis and cytokine assay revealed that schaftoside also regulated immune response and inflammation of the host cells. The antiinflammatory activities of schaftoside were confirmed on lipopolysaccharide-induced acute lung injury mice. Schaftoside showed good safety and pharmacokinetic property, and could be a promising drug candidate for the prevention and treatment of COVID-19. | Yang Yi Meng Zhang Heng Xue Rong Yu Yang-Oujie Bao Yi Kuang Yue Chai Wen Ma Jing Wang Xiaomeng Shi Wenzhe Li Wei Hong Junhua Li Elishiba Muturi Hongping Wei Joachim Wlodarz Szczepan Roszak Xue Qiao Hang Yang Min Ye | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 0 |
| 9 | Deposition Effects of Electrostatic and NonElectrostatic Aerial Spray显示文摘In this study,we compared the aerial electrostatic spray with non-electrostatic spray by helicopter R44 and fixed-wing aircraft Y5B equipped with an own-made aerial electrostatic spraying system.The results showed that the spray deposits on targets and leaves of tree crowns were notable enhanced comparing with the non-electrostatic and conventional aerial spray.The spray deposits were fine,uniform and the densities were 1.0-1.75 times higher than the non-electrostatic spray.Deposit rate of the electrostatic spray on the backs of leaves by helicopter R44 was 2.15 times of the non-electrostatic, and 3.31 times of the conventional aerial spray.The deposit rate of the electrostatic spray on the backs of leaves by the Y5B was 2.38 times of the non-electrostatic,and 3.44 times of the conventional aerial spray. | Shu Chaoran Pan Hongyang Zhou Hongping Zhan Min Mei Aihua Ru Yu Jia Zhicheng Chen Guofa | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 10 | Licorice-saponin A3 is a broad-spectrum inhibitor for COVID-19 by targeting viral spike and anti-inflammation显示文摘Currently,human health due to corona virus disease 2019(COVID-19)pandemic has been seriously threatened.The coronavirus severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)spike(S)protein plays a crucial role in virus transmission and several S-based therapeutic approaches have been approved for the treatment of COVID-19.However,the efficacy is compromised by the SARS-CoV-2 evolvement and mutation.Here we report the SARS-CoV-2 S protein receptor-binding domain(RBD)inhibitor licorice-saponin A3(A3)could widely inhibit RBD of SARS-CoV-2 variants,including Beta,Delta,and Omicron BA.1,XBB and BQ1.1.Furthermore,A3 could potently inhibit SARS-CoV-2 Omicron virus in Vero E6 cells,with EC50 of 1.016μM.The mechanism was related to binding with Y453 of RBD determined by hydrogen-deuterium exchange mass spectrometry(HDX-MS)analysis combined with quantum mechanics/molecular mechanics(QM/MM)simulations.Interestingly,phosphoproteomics analysis and multi fluorescent immunohistochemistry(mIHC)respectively indicated that A3 also inhibits host inflammation by directly modulating the JNK and p38 mitogen-activated protein kinase(MAPK)pathways and rebalancing the corresponding immune dysregulation.This work supports A3 as a promising broad-spectrum small molecule drug candidate for COVID-19. | Yang Yi Wenzhe Li Kefang Liu Heng Xue Rong Yu Meng Zhang Yang-Oujie Bao Xinyuan Lai Jingjing Fan Yuxi Huang Jing Wang Xiaomeng Shi Junhua Li Hongping Wei Kuanhui Xiang Linjie Li Rong Zhang Xin Zhao Xue Qiao Hang Yang Min Ye | 2024 | Journal of Pharmaceutical Analysis2024，14，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员