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| 1 | Healthy function and high valued utilization of edible fungi显示文摘Edible fungi are large fungi with high added value that can be utilized as resources.They are rich in high-quality protein,carbohydrate,various vitamins,mineral elements and other nutrients,and are characterized by high protein,low sugar,low fat and low cholesterol.In addition,edible fungi contain a variety of bioactive substances,such as polysaccharides,dietary fiber,steroids,polyphenols,and most of these compounds have antioxidant,anti-tumor and other physiological functions.This review comprehensively discusses the bioactive components and functional characteristics of edible fungi(such as antioxidant,anti-aging,hypolipidemic activities,etc.).Then the recent developments and prospect in the high-valued utilization of edible fungi are discussed and summarized.The objective of this review is to improve the understanding of health-promoting properties of edible fungi,and provide reference for the industrial production of edible fungi-based health products. | Yanrong Zhang Dawei Wang Yuetong Chen Tingting Liu Shanshan Zhang Hongxiu Fan Hongcheng Liu Yu Li | 2021 | Food Science and Human Wellness2021，10，4： | 20 |
| 2 | Targets and molecular mechanisms of triptolide in cancer therapy显示文摘Triptolide(TPL/TL) is a natural drug with novel anticancer effects. Preclinical studies indicated that TPL inhibits cell proliferation, induces cell apoptosis, inhibits tumor metastasis and enhances the effect of other therapeutic methods in various cancer cell lines. Multiple molecules and signaling pathways, such as caspases, heat-shock proteins, NF-κB, and deoxyribonucleic acid(DNA) repair-associated factors, are associated with the anti-cancer effect. TPL also improves chemoradiosensitivity in cancer therapy. Phase I trials indicate the potential clinical value of TPL use. However, further trials with larger sample sizes are needed to confirm these results. | Cuicui Meng Hongcheng Zhu Hongmei Song Zhongming Wang Guanhong Huang Defan Li Zhaoming Ma Jianhua Ma Qin Qin Xinchen Sun Jianxin Ma | 2014 | Chinese Journal of Cancer Research2014，26，5： | 16 |
| 3 | MdGSTF6,activated by MdMYB1,plays an essential role in anthocyanin accumulation in apple显示文摘Anthocyanins are biosynthesized on the cytosolic surface of the endoplasmic reticulum and then transported into the vacuole for storage.Glutathione S-transferases(GSTs)are considered to be responsible for the transport of anthocyanins into the vacuole.However,the regulatory mechanisms of GSTs in plants are still unclear.Here,we performed a genome-wide analysis and identified 69 GST genes in apple.The expression of MdGSTF6 was positively correlated with the anthocyanin content(r=0.949)during‘Yanfu 8’fruit development.The overexpression of MdGSTF6 in the Arabidopsis thaliana tt19 mutant resulted in seedlings of 35S::MdGSTF6-GFP/tt19 that could accumulate anthocyanin and rescue its phenotype,suggesting that MdGSTF6 was an anthocyanin transporter.The silencing of MdGSTF6 affected anthocyanin accumulation in apple fruit.Moreover,the knockdown of MdGSTF6 by RNA interference in cultured‘Gala’seedlings inhibited anthocyanin accumulation.The interaction experiments showed that MdMYB1 could bind directly to the MdGSTF6 promoter to transcriptionally activate its expression.Collectively,our results demonstrate that MdGSTF6 encodes an important GST transporter of anthocyanins in apple fruit and provide evidence for the associated regulatory mechanisms.Therefore,MdMYB1 can not only regulate anthocyanin synthesis,but also control the transport of anthocyanin in apples.This information may be useful for further clarifying the regulation of anthocyanin transport in apple. | Shenghui Jiang Min Chen Naibo He Xiaoliu Chen Nan Wang Qingguo Sun Tianliang Zhang Haifeng Xu Hongcheng Fang Yicheng Wang Zongying Zhang Shujing Wu Xuesen Chen | 2019 | Horticulture Research2019，6，1： | 16 |
| 4 | Malus sieversii: the origin, flavonoid synthesis mechanism, and breeding of red-skinned and red-fleshed apples显示文摘Flavonoids play essential roles in human health.Apple(Malus domestica Borkh.),one of the most widely produced and economically important fruit crops in temperate regions,is a significant source of flavonoids in the human diet and is among the top nutritionally rated and most widely consumed fruits worldwide.Epidemiological studies have shown that the consumption of apples,which are rich in a variety of free and easily absorbable flavonoids,is associated with a decreased risk of various diseases.However,apple production is challenged by serious inbreeding problems.The narrowing of the hereditary base has resulted in apples with poor nutritional quality and low flavonoid contents.Recently,there have been advances in our understanding of the roles that Malus sieversii(Ledeb.)M.Roem has played in the process of apple domestication and breeding.In this study,we review the origin of cultivated apples and red-fleshed apples,and discuss the genetic diversity and construction of the core collections of M.sieversii.We also discuss current research progress and breeding programs on red-skinned and red-fleshed apples and summarize the exploitation and utilization of M.sieversii in the breeding of high-flavonoid,and red-fleshed apples.This study highlights a valuable pattern of horticultural crop breeding using wild germplasm resources.The future challenges and directions of research on the molecular mechanisms of flavonoid accumulation and high-flavonoid apple breeding are discussed. | Nan Wang Shenghui Jiang Zongying Zhang Hongcheng Fang Haifeng Xu Yicheng Wang Xuesen Chen | 2018 | Horticulture Research2018，5，1： | 15 |
| 5 | 基于星载激光雷达GLAS和光学MODIS数据中国森林冠层高度制图显示文摘星载GLAS波形数据精确记录了光斑内所有探测目标的垂直结构信息,在森林结构参数反演方面具有极大的应用潜力,但GLAS激光脚印是不连续分布的离散点且密度较低(中国地区平均约为0.14 point/km2),因此仅利用GLAS数据不能获得高精度的连续植被高度分布.已有研究表明,相对其他光学数据及反演参数,MODIS BRDF参数最能反映植被结构信息.本文利用同时期(2008年2月)的GLAS与MODIS数据,首先采用小波分析方法提取GLAS数据的波形特征参数,通过ASTER GDEM数据计算地形指数,并辅以植被分类数据分三种森林类型分别建立基于波形特征参数和地形指数的树高估算模型;然后,通过神经网络训练建立基于GLAS树高和最佳MODIS BRDF波段组合的树高反演模型,并应用该模型得到中国森林植被平均高度的连续分布图;最后,利用野外实测树高和机载激光雷达数据提取树高分别对反演结果进行验证,结果表明该模型反演精度较高. | 杨婷 王成 李贵才 骆社周 习晓环 高帅 HongCheng ZENG | 2014 | 中国科学:地球科学2014，44，11： | 13 |
| 6 | Isolation,purification,structural characteristic and antioxidative property of polysaccharides from A.cepa L.var.agrogatum Don显示文摘Allium cepa L.var.agrogatum Don(ALAP)is commonly consumed in China as well as other regions and has various beneficial health effects.A novel acidic polysaccharide(named ALAP-21)was obtained from ALAP by ultrasonic and microwave-assisted extraction and purification using DEAE-52 anion exchange and Sephadex G-100 columns.The monosaccharide composition,structural and antioxidative properties of ALAP-21 were investigated by GC–MS chromatography,FT-IR and NMR spectroscopies and three antioxidative activity tests in vitro.The results showed that ALAP-21 was a heteropolysaccharide composed of glucose,galacturonic acid,mannose,galactose,arabinose,rhamnose,xylose,fructose and glucuronic acid with a relative molar ratio of 26.282:27.546:11.400:4.781:2.467:2.445:3.622:1.106:1.753,owning(1→4)-β-d-Glcp,(1→4)-β-d-GalAp6Me3OA,(1→4)-β-d-Galp6OMe,(1→2)-β-l-Rhap,(1→4)-β-d-Manp glycosidic linkages.(1→4)-β-d-Glcp and(1→4)-β-d-GalAp6Me3OA residues might be the main components of the sugar chain backbone of ALAP-21.Furthermore,ALAP-21 exhibited high potential for DPPH radicals(82.02%),hydroxyl radicals(53.33%)and superoxide anion radicals(50.28%).These results provide a reference for further research and rational development of ALAP polysaccharides. | Hongcheng Liu Hongxiu Fan Jing Zhang Shanshan Zhang Wenting Zhao Tingting Liu Dawei Wang | 2020 | Food Science and Human Wellness2020，9，1： | 10 |
| 7 | Equivalent Currents on an Anisotropic MaterialBacked by a Metal Surface and Their Relation显示文摘Based on a first-order state-vector differential equation representation of Maxwell’s equations, an analytical formulation is derived for the equivalent currents on an anisotropic material backed by a metal surface, and the relation between two currents is also considered. These expressions are degenerated into the common forms for some simple cases. This effort will provide the theoretical preparation for the approximate calculation of electromagnetic scattering from a conducting object coated by an anisotropic material. | Huang Peikang Yin Hongcheng | 2000 | Journal of Systems Engineering and Electronics2000，11，4： | 10 |
| 8 | Textural Evolution of AZ31B Magnesium Alloy Sheets Undergoing Repeated Unidirectional Bending at Room Temperature显示文摘In this paper, repeated unidirectional bending (RUB), was applied to improve the texture of AZ31B magnesium alloy sheets so as to enhance their stamping properties. The samples undergoing RUB were annealed at different temperatures. The mechanical properties, formability, textural components and microstructure of the samples before and after RUB were characterized and compared. It was found that the basal textural component was reduced dramatically by RUB, and that (12ˉ12) and (12ˉ11) textural components appeared. Annealing has a great effect on the mechanical properties of samples undergoing RUB. The plasticity and stamping formability of samples were greatly improved by RUB and annealing at 260?C for 1 h, and elongation to fracture and Erichsen value were increased to 38% and 67%, respectively. | Guangsheng Huang Wei Xu Guangjie Huang Hongcheng Li Bo Song | 2009 | Journal of Materials Science & Technology2009，25，3： | 9 |
| 9 | Forest canopy height mapping over China using GLAS and MODIS data显示文摘The Geoscience Laser Altimeter System(GLAS)accurately detects the vertical structural information of a target within its laser spot and is a promising system for the inversion of structural features and other biophysical parameters of forest ecosystems.Since the GLAS footprints are discontinuously distributed with a relativity low density,continuous vegetation height distributions cannot be mapped with a high accuracy using GLAS data alone.The MODIS BRDF product provides more forest structural information than other optical remote sensing data.This study aimed to map forest canopy heights over China from the GLAS and MODIS BRDF data.Firstly,the waveform characteristic parameters were extracted from the GLAS data by the method of wavelet analysis,and the terrain index was calculated using the ASTER GDEM data.Secondly,the model reducing the topographic influence was constructed from the waveform characteristic parameters and terrain index.Thirdly,the final canopy height estimation model was constructed from the neural network combining the canopy height estimated with the GLAS point and the MODIS BRDF data,and applied to get the continuous canopy height map over China.Finally,the map was validated by the measured data and the airborne Li DAR data,and the validation results indicated that forest canopy heights can be estimated with high accuracy from combined GLAS and MODIS data. | YANG Ting WANG Cheng LI GuiCai LUO SheZhou XI XiaoHuan GAO Shuai ZENG HongCheng | 2015 | Science China Earth Sciences2015，58，1： | 8 |
| 10 | Relating Cd2+binding by humic acids to molecular weight:A modeling and spectroscopic study显示文摘Molecular weight(Mw) is a fundamental property of humic acids(HAs), which considerably affect the mobility and speciation of heavy metals in the environment. In this study, soil humic acid(HA) extracted from Jinyun Mountain, Chongqing was ultra-filtered into four fractions according to the molecular weight, and their properties were characterized.Complexation of cadmium was investigated by titration experiments. For the first time,Langmuir and non-ideal competitive adsorption-Donna(NICA-Donnan) models combined with fluorescence excitation-emission matrix(EEM) quenching were employed to elucidate the binding characteristics of individual Mw fractions of HA. The results showed that the concentration of acidic functional groups decreased with increasing Mw, especially the phenolic groups. The humification degree and aliphaticity increased with increasing Mw as indicated by elemental composition analysis and FT-IR spectra. The binding capacity of Cd^(2+) to Mw fractions of HA followed the order UF1(< 5 kDa) > UF2(5–10 kDa) > UF4(> 30 kDa) > UF3(10–30 kDa). Moreover, the distribution of cadmium speciation indicated that the phenolic groups were responsible for the variations in binding of Cd^(2+) among different Mw fractions. The results of fluorescence quenching illustrated that the binding capacity of Cd^(2+) to Mw fractions was controlled by the content of functional groups, while the binding affinity was largely influenced by structural factors. The results provide a better understanding of the roles that different HA Mw fractions play in heavy metal binding,which has important implications in the control of heavy metal migration and bio-toxicity. | Hongcheng Bai Zhenmao Jiang Minjin He Biying Ye Shiqiang Wei | 2018 | Journal of Environmental Sciences2018，30，8： | 7 |
| 11 | MdMYB6 regulates anthocyanin formation in apple both through direct inhibition of the biosynthesis pathway and through substrate removal显示文摘Anthocyanin biosynthesis and sugar metabolism are important processes during plant growth,but the molecular interactions underlying these pathways are still unclear.In this work,we analyzed the anthocyanin and soluble sugar contents,as well as the transcript levels of transcription factors that are known to be related to the biosynthesis of anthocyanin in‘Hongcui 1’apple flesh during fruit development.Overexpression of MdMYB6 in red-fleshed calli was found to reduce anthocyanin content and result in downregulated expression of the MdANS and MdGSTF12 proteins.Yeast one-hybrid and electrophoretic mobility shift analyses showed that MdMYB6 could directly bind to the promoters of MdANS and MdGSTF12,indicating that MdMYB6 could inhibit anthocyanin biosynthesis by regulating MdANS and MdGSTF12.Overexpression of MdTMT1 in the Arabidopsis tmt1 mutant restored the glucose and fructose contents to the wild-type levels,while overexpression of MdTMT1 in red-fleshed calli increased the contents of glucose and fructose but reduced the contents of UDP-glucose,UDP-galactose,and anthocyanin.Using a GUS reporter system,yeast one-hybrid,chromatin immunoprecipitation-PCR and electrophoretic mobility shift analyses,we found that MdMYB6 could bind to the promoter of MdTMT1,resulting in increased promoter activity.Overexpression of MdMYB6 in calli overexpressing MdTMT1 increased the expression of MdTMT1,which led to reduced contents of UDP-glucose and UDP-galactose and decreased anthocyanin content compared to those of the calli that overexpressed MdTMT1.This finding suggested that MdMYB6 could also inhibit anthocyanin biosynthesis by regulating MdTMT1 to decrease the contents of UDP-glucose and UDP-galactose.Taken together,these results showed that MdMYB6 and MdTMT1 play key roles in both anthocyanin biosynthesis and sugar transport. | Haifeng Xu Qi Zou Guanxian Yang Shenghui Jiang Hongcheng Fang Yicheng Wang Jing Zhang Zongying Zhang Nan Wang Xuesen Chen | 2020 | Horticulture Research2020，7，1： | 6 |
| 12 | Preliminary Discussion on the Relationship Between EM Wave Propagation Characteristics and Medium Parameters in Anisotropic Medium显示文摘The reflection and transmission characteristics of an anisotropic half-space medium normally illuminated by aplane wave are analyzed by kDB coordination. The general formula of reflection coefficient at the air-medium interface isgiven, and its validity is also discussed. The possible propagating modes in different mediums and the effect of medium pa-rameters on these modes are emphatically studied. This work provides the theoretical preparations for the parameter recon-struction of an anisotropic material. | Guo Huiping & Liu Xueguan Dept. of Communication and Electronics, Suzhou University, Suzhou 215021, P. R. ChinaYin Hongcheng & Huang Peikang National Electromagnetic Scattering Laboratory, Beijing 100854, P. R. China | 2002 | Journal of Systems Engineering and Electronics2002，13，4： | 6 |
| 13 | A single center experience: post-transplantation adjuvant chemotherapy impacts the prognosis of hepatocellular carcinoma patients显示文摘 | Wu Junyi Sun Hongcheng Han Zhongbo Peng Zhihai | 2014 | Chinese Medical Journal2014，，3： | 6 |
| 14 | Clinicopathologic study of mucosa-associated lymphoid tissue lymphoma in gastroscopic biopsy显示文摘AIM: To explore and discuss the clinicopathologic characteristics of mucosa-associated lymphoid tissue (MALT)lymphoma in gastroscopic biopsy specimen.
METHODS: A retrospective study of 26 cases of lymphoma diagnosed by gastroscopic biopsy during 1999 to 2001 from gastroscopy files of Xijing Hospital was made. The diagnostic criteria were adopted according to the new classification of non-Hodgkin's lymphoma.
RESULTS: Twenty-six cases of primary gastric lymphoma consisting of 15 men and 11 women, aged between 23 to 76 years were recruited from 6 225 cases who Received gastroscopy. All of them were diagnosed by both endoscopic findings and histological examinations. Histologically, 23cases were MALToma (low grade) and 3 cases lymphoblastic lymphoma (high grade). Immunohistochemically, all cases were CD20 positive, while CK and EMA were negative.
CONCLUSION: The majority of the cases of primary lowgrade gastric lymphoma have morphologic and clinical features that justify their inclusion in the category of lowgrade lymphoma of mucosa associated lymphoid tissue. | HongCheng JunWang Chuan-ShanZhang Pei-SongYan Xiao-HuiZhang Pei-ZhenHu Fu-ChengMa | 2003 | World Journal of Gastroenterology2003，9，6： | 5 |
| 15 | In-line X-ray phase-contrast imaging of murine liver microvasculature ex vivo显示文摘Imaging blood vessels is of importance for determining the vascular distribution of organs and tumors.Phase-contrast X-ray imaging can reveal the vessels in much more detail than conventional X-ray absorption method.Visualizing murine liver microvasculature ex vivo with phase-contrast X-ray imaging was performed at Shanghai Synchrotron Radiation Facility.Barium sulfate and physiological saline were used as contrast agents for the blood vessels.Blood vessels of <Φ20μm could be detected by replacing resident blood with physiological saline or barium sulfate.An entire branch of the portal vein (from the main axial portal vein to the ninth generation of branching) could be captured in a single phase-contrast image.It is demonstrated that selective angiography based on phase contrast X-ray imaging,with a physiological material of low Z elements (such as saline) being the contrast agent,is a viable imaging strategy.Further efforts will be focused on using the technique to image tumor angiogenesis. | LI Beilei XU Min WU Weizhong PENG Guanyun ZHANG Xi PENG Yifeng SHI Hongcheng CHEN Shaoliang | 2012 | Nuclear Science and Techniques2012，23，1： | 5 |
| 16 | The latest process and challenges of microwave dielectric ceramics based on pseudo phase diagrams显示文摘The explosive process of 5G communication evokes the urgent demand of miniaturized and integrated dielectric ceramics filter It is a pressing need to advance the development of dielectric ceramics utilization of emerging technology to design new materials and understand the polarization mechanism.This review provides the summary of the study of microwave dielectric ceramics(MWDCs)sintered higher than 1000℃ from 2010 up to now,with the purpose of taking a broad and historical view of these ceramics and illustrating research directions.To date,researchers endeavor to explain the structure-property relationship of ceramics with multitude of approaches and design a new formula or strategy to obtain excellent microwave dielectric properties.There are variety of factors that impact the permittivity,dielectric loss,and temperature stability of dielectric materials,covering intrinsic and extrinsic factors.Many of these factors are often intertwined,which can complicate new dielectric material discovery and the mechanism investigation.Because of the various ceramics systems,pseudo phase diagram was used to classify the dielectric materials based on the composition.In this review,the ceramics were firstly divided into ternary systems,and then brief description of the experimental probes and complementary theoretical methods that have been used to discern the intrinsic polarization mechanisms and the origin of intrinsic loss was mentioned.Finally,some perspectives on the future outlook for high-temperature MWDCs were offered based on the synthesis method,characterization techniques,and significant theory developments. | Hongcheng YANG Shuren ZHANG Hongyu YANG Qingyu WEN Qiu YANG Ling GUI Qian ZHAO Enzhu LI | 2021 | Journal of Advanced Ceramics2021，10，5： | 5 |
| 17 | Dynamic microwave-assisted extraction combined with liquid phase microextraction based on the solidification of a floating drop for the analysis of organochlorine pesticides in grains followed by GC显示文摘A convenient,cost-effective and fast method using dynamic microwave-assisted extraction and liquid phase microextraction based on the solidification of a floating drop was proposed to analyze organochlorine pesticides in grains including rice,maize and millet.Twelve samples can be processed simultaneously in the method.During the extraction process,10%acetonitrile-water solutions containing 110μL of n-hexadecane were used to extract organochlorine pesticides.Subsequently,1.0 g sodium chloride was placed in the extract,and then centrifuged and cooled.The n-hexadecane drops containing the analytes were solidifi ed and transferred for determination by gas chromatography-electron capture detector without any further filtration or cleaning process.Limits of detection for organochlorine pesticides were 0.97–1.01μg/kg and the RSDs were in the range of 2.6%–8.5%.The developed technology has succeeded in analyzing six real grains samples and the recoveries of the organochlorine pesticides were 72.2%–94.3%.Compared with the published extraction methods,the developed method was used to analyze organochlorine pesticides in grains,being more environmentally friendly,which is suitable for the daily determination of organochlorine pesticides. | Guijie Li Xu Zhang Tingting Liu Hongxiu Fan Hongcheng Liu Shangyu Li Dawei Wang Lan Ding | 2021 | Food Science and Human Wellness2021，10，3： | 4 |
| 18 | Flexible Waterproof Piezoresistive Pressure Sensors with Wide Linear Working Range Based on Conductive Fabrics显示文摘Developing flexible sensors with high working performance holds intense interest for diverse applications in leveraging the Internet-of-things(IoT)infrastructures.For flexible piezoresistive sensors,traditionally most efforts are focused on tailoring the sensing materials to enhance the contact resistance variation for improving the sensitivity and working range,and it,however,remains challenging to simultaneously achieve flexible sensor with a linear working range over a high-pressure region(>100 kPa)and keep a reliable sensitivity.Herein,we devised a laserengraved silver-coated fabric as'soft'sensor electrode material to markedly advance the flexible sensor's linear working range to a level of 800 kPa with a high sensitivity of 6.4 kPa^-1 yet a fast response time of only 4 ms as well as long-time durability,which was rarely reported before.The integrated sensor successfully routed the wireless signal of pulse rate to the portable smartphone,further demonstrating its potential as a reliable electronic.Along with the rationally building the electrode instead of merely focusing on sensing materials capable of significantly improving the sensor's performance,we expect that this design concept and sensor system could potentially pave the way for developing more advanced wearable electronics in the future. | Hongcheng Xu Libo Gao Yuejiao Wang Ke Cao Xinkang Hu Liang Wang Meng Mu Min Liu Haiyan Zhang Weidong Wang Yang Lu | 2020 | Nano-Micro Letters2020，12，11： | 4 |
| 19 | Biomass-derived activated carbon materials with plentiful heteroatoms for high-performance electrochemical capacitor electrodes显示文摘Activated carbons for electrochemical capacitor electrodes are prepared from soyabean using chemical activation with KOH. The pore size is easily controllable by changing the mass ratio between KOH and carbonized product. The as-prepared materials possess a large specific surface area, unique structure, well- developed hierarchical porosity and plentiful heteroatoms(mainly O and N). Thus resulted in its high specific capacitance,good rate capacity and cycling stability. Moreover, attributing to worldwide availability, renewable nature and low-cost, activated carbon prepared from soyabean has a good potential in energy conversion and storage devices. | Xiangyang Zhou Hongcheng Li Juan Yang | 2016 | Journal of Energy Chemistry2016，25，1： | 4 |
| 20 | Facile Synthesis of Cellulose Acetate Ultrafiltration Membrane with Stimuli-Responsiveness to pH and Temperature Using the Additive of F127-b-PDMAEMA显示文摘 | Naixu Li Jun Yin LingfeiWei Quanhao Shen Wei Tian Jing Li Yong Chen Jing Jin Hongcheng Teng Jiancheng Zhou | 2017 | Chinese Journal of Chemistry2017，35，7： | 4 |
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