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| 1 | Development and validation of a questionnaire-based risk scoring system to identify individuals at high risk for gastric cancer in Chinese populations显示文摘Objective:This study aimed to develop and validate a risk scoring system to identify high-risk individuals carrying malignant lesions in stomach for tailored gastric cancer screening.Methods:A gastric cancer risk scoring system(GC-RSS)was developed based on questionnaire-based predictors for gastric cancer derived from systematic literature review.To assess the capability of this system for discrimination,risk scores for 8,214 and 7,235 outpatient subjects accepting endoscopic examination in two endoscopy centers,and 32,630 participants in a community-based cohort in China were calculated to plot receiver operating characteristic curves and generate area under the curve(AUC).To evaluate the performance of GC-RSS,the screening proportion,sensitivity and detection rate ratio compared to universal screening were used under different risk score cutoff values.Results:GC-RSS comprised nine predictors including advanced age,male gender,low body mass index(<18.5 kg/m^(2)),family history of gastric cancer,cigarette smoking,consumption of alcohol,preference for salty food,irregularity of meals and consumption of preserved food.This tool performed well in determining the risk of malignant gastric lesions with AUCs of 0.763,0.706 and 0.696 in three validation sets.When subjects with risk scores≥5 were evaluated with endoscopy,nearly 50%of these endoscopies could be saved with a detection rate of over 1.5 times achieved.When the cutoff was set at 8,only about 10%of subjects with the highest risk would be offered endoscopy,and detection rates for gastric cancer could be increased 2-4 fold compared to universal screening.Conclusions:An effective questionnaire-based GC-RSS was developed and validated.This tool may play an important role in establishing a tailored screening strategy for gastric cancer in China. | Ren Zhou Hongchen Zheng Mengfei Liu Zhen Liu Chuanhai Guo Hongrui Tian Fangfang Liu Ying Liu Yaqi Pan Huanyu Chen Zhe Hu Hong Cai Zhonghu He Yang Ke | 2021 | Chinese Journal of Cancer Research2021，33，6： | 3 |
| 2 | Methane formation route in the conversion of methanol to hydrocarbons显示文摘The influence factors and paths of methane formation during methanol to hydrocarbons(MTH) reaction were studied experimentally and thermodynamically. The fixed-bed reaction results show that the formation of methane was favored by not only high temperature, but also high feed velocity, low pressure, as well as weak acid sites dominated on deactivated catalyst. The thermodynamic analysis results indicate that methane would be formed via the decomposition reactions of methanol and DME, and the hydrogenolysis reactions of methanol and DME. The decomposition reactions are thermal chemistry processes and easily occurred at high temperature. However, they are influenced by catalyst and reaction conditions through DME intermediate. By contrast, the hydrogenolysis reactions belong to catalytic processes. Parallel experiments suggest that, in real MTH reactions, the hydrogenolysis reactions should be mainly enabled by surface active H atom which might come from hydrogen transfer reactions such as aromatization. But H2will be involved if the catalyst has active components like NiO. | Wenping Zhao Baozhu Zhang Guiru Wang Hongchen Guo | 2014 | Journal of Energy Chemistry2014，23，2： | 3 |
| 3 | Facile preparation of bi-functional iron doped mesoporous materials and their application in the cycloaddition of CO2显示文摘Two kinds of bi-functional transition metal doped mesoporous materials(Fe-HMS and Fe-MCM-41) are prepared using one-step hydrothermal method and then treated with hydrochloric acid ethanol solution.The N2 adsorption and HRTEM results show that both of Fe-HMS and Fe-MCM-41 possess mesoporous structure. The UV–vis results suggest that the Fe species are mainly located within the framework. The basicity of as-prepared samples was studied by temperature programmed desorption using CO2 as probe molecule(CO2-TPD). The catalytic performance of Fe-HMS and Fe-MCM-41 in CO2 cycloaddition largely depends on the amount of the accessible basic sites. The acid–base active sites, framework Fe and PDDA species cooperatively catalyze the CO2 cycloaddition for the production of cyclic carbonates under the condition without any co-catalyst. The conversion of epichlorohydrin(ECH) is 97.4% and the selectivity of chloropropene carbonate is 92.9% under optimal conditions. The approximate rate constant of cycloaddition reaction of CO2 with ECH under optimum reaction temperature is calculated. It is worth noting that the Fe-HMS material shows superior reusability than Fe-MCM-41. In addition, this work provides a facile way on the synthesis of bi-functional acid–base heterogeneous catalyst with outstanding catalytic performance for the fixation of CO2. | Dan Liu Gang Li Hongchen Guo Jiaxu Liu | 2020 | Journal of Energy Chemistry2020，29，2： | 2 |
| 4 | A critical review of mineral–microbe interaction and co-evolution:mechanisms and applications显示文摘Mineral–microbe interactions play important roles in environmental change,biogeochemical cycling of elements and formation of ore deposits.Minerals provide both beneficial(physical and chemical protection,nutrients,and energy)and detrimental(toxic substances and oxidative pressure)effects to microbes,resulting in mineral-specific microbial colonization.Microbes impact dissolution,transformation and precipitation of minerals through their activity,resulting in either genetically controlled or metabolism-induced biomineralization.Through these interactions,minerals and microbes co-evolve through Earth history.Mineral–microbe interactions typically occur at microscopic scale but the effect is often manifested at global scale.Despite advances achieved through decades of research,major questions remain.Four areas are identified for future research:integrating mineral and microbial ecology,establishing mineral biosignatures,linking laboratory mechanistic investigation to field observation,and manipulating mineral–microbe interactions for the benefit of humankind. | Hailiang Dong Liuqin Huang Linduo Zhao Qiang Zeng Xiaolei Liu Yizhi Sheng Liang Shi Geng Wu Hongchen Jiang Fangru Li Li Zhang Dongyi Guo Gaoyuan Li Weiguo Hou Hongyu Chen | 2022 | National Science Review2022，9，10： | 2 |
| 5 | Study of the per- formance of modified nano-scale ZSM-5 zeolite on olefins reduction in FCC gasoline 显示文摘 | Zhang Peiqing Guo Xinwen Guo Hongchen | 2007 | Journal of Molecular Catalysis A : Chemical2007，261，： | 1 |
| 6 | Pt supported on Zn modified silicalite-1 zeolite as a catalyst for n-hexane aromatization显示文摘Platinum(Pt)supported on Zinc(Zn)modified silicalite-1(S-1)zeolite(denoted as Pt-Zn/S-1)was prepared by using a wetness-impregnation method and applied in the n-hexane aromatization reaction for the first time.Both Lewis and Bronsted acid sites were detected in Pt-Zn/S-1 catalyst by means of FT-IR adsorption of NH3 experiment,which were identified as mostly weak and medium ones.Besides,Pt and Zn species showed strong interaction,as revealed by the TPR(Temperature-programmed reduction)and XPS(X-ray photoelectron spectroscopy)experiments.Pt-Zn/S-1 catalyst exhibited excellent aromatization function rather than isomerization and cracking side reactions in the conversion of n-hexane.Pulse experimental study showed that 75.6%of n-hexane conversion and 76.8%of benzene selectivity were obtained over Pt0.1-Zn60/S-l catalyst at 550℃ and under atmospheric pressure.By spectroscopy tests and pulse experimental results,it was concluded that the n-hexane aromatization over Pt-Zn/S-1 catalyst follows a metal-acid bifunctional mechanism.Furthermore,with the assistance of Zn,the electron-deficient Pt species in Pt-Zn/S-1 showed good sulfur tolerance performance. | Guodong Liu Jiaxu Liu Ning He Shishan Sheng Guiru Wang Hongchen Guo | 2019 | Journal of Energy Chemistry2019，28，7： | 1 |
| 7 | Precise measurement of gravity variation during a total solar eclipse显示文摘 | Wang Qianshen Yang Xinshe Wu Chuanzhen Guo Honggang Liu Hongchen and Hua Changchai | 2000 | Physical Review D2000，62，04： | 1 |
| 8 | Hydroconversion of n-octane over nanoscale HZSM-5 zeolites promoted by 12- molybdo Phosphoric acid and Ni显示文摘 | Chen Lidong Wang Xiangsheng Guo Hongchen | 2007 | Catalysis Communications2007，8，： | 1 |
| 9 | Study of the performance of modified nano-scale ZSM-5 zeolite on olefins reduction in FCC gasoline 显示文摘 | Zhang Peiqing Guo Xinwen Guo Hongchen | 2007 | Journal of Molecular Catalysis A : Chemical2007，261，2： | 1 |
| 10 | Direct and continuous synthesis of concentrated hydro- gen peroxide by the gaseous reaction of HJO2 non-equi-librium plasma 显示文摘 | Zhou Juneheng Guo Hongchen Wang Xiangsheng | 2005 | Chem Commun2005，，： | 1 |
| 11 | TiO2/Na-HZSM-5 nano-composite photocatalyst:Reversible adsorption by acid sites promotes photocatalytic decomposition of methyl orange显示文摘 | Guo Peng Wang Xiangsheng Guo Hongchen | | 0，，： | 1 |
| 12 | Direct and continuous synthesis of concentrated hydrogen peroxide by the gaseous reaction of H2/O2 nonequilibrium plasma显示文摘 | Zhou Juncheng Guo Hongchen Wang Xiangsheng | 2005 | Chem Commun2005，，： | 1 |
| 13 | Effects of Pulsed Electromagnetic Fields on Bone Mass and Wnt/β-Catenin Signaling Pathway in Ovariectomized Rats显示文摘 | Jun Zhou Hongchen He Lin Yang Shiju Chen Hua Guo Lu Xia Huifang Liu Yuxi Qin Chuan Liu Xiaofei Wei Yujing Zhou Chengqi He | 2012 | Archives of Medical Research2012，，4： | 1 |
| 14 | Direct and continuous synthesis of concentrated hydrogen peroxide by the gaseous reaction of H2/O2 non-equilibrium plasma显示文摘 | Guo Hongchen Wang Xiangsheng | 2005 | Chem Commun2005，，： | 1 |
| 15 | Diversity and Abundance of Ammonia-Oxidizing Archaea and Bacteria in Qinghai Lake, Northwestern China显示文摘 | Hongchen Jiang Hailiang Dong Bingsong Yu Guo Lv Shicai Deng Nicole Berzins Minhan Dai | 2009 | Geomicrobiology Journal2009，，3： | 1 |
| 16 | Hydroconversion of n-octane over nanoscale HZSM-5 zeolites promoted by 12-molybdoPhosphoric acid and Ni显示文摘 | Chen Lidong Wang Xiangsheng Guo Hongchen | 2007 | Catalysis Communications2007，8，： | 1 |
| 17 | 显示文摘 | Wang Xiangsheng Guo Hongchen | 2003 | Chin J Catal2003，24，3： | 1 |
| 18 | Study of the performance of modified nano-scale ZSM-5 zeolite on ole- fins reduction in FCC gasoline显示文摘 | Zhang Peiqing Guo Xinwen Guo Hongchen | 2007 | J Mol Catal A2007，26，2： | 1 |
| 19 | Study of the performance of modified nano-scale ZSM-5 zeolite on olefinsreduction in FCC gasoline显示文摘 | Zhang Peiqing Guo Xinwen Guo Hongchen | 2007 | J Mol Catal A Chem2007，261，： | 1 |
| 20 | Immunomodulatory effects and mechanisms of distraction osteogenesis显示文摘Distraction osteogenesis(DO) is widely used for bone tissue engineering technology. Immune regulations play important roles in the process of DO like other bone regeneration mechanisms. Compared with others, the immune regulation processes of DO have their distinct features. In this review, we summarized the immune-related events including changes in and effects of immune cells, immune-related cytokines, and signaling pathways at different periods in the process of DO. We aim to elucidated our understanding and unknowns about the immunomodulatory role of DO. The goal of this is to use the known knowledge to further modify existing methods of DO, and to develop novel DO strategies in our unknown areas through more detailed studies of the work we have done. | Shude Yang Ning Wang Yutong Ma Shuaichen Guo Shu Guo Hongchen Sun | 2022 | International Journal of Oral Science2022，14，1： | 1 |
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