|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis?显示文摘Beside many efforts to improve outcome, sepsis is still one of the most frequent causes of death in critically ill patients. It is the most common condition with high mortality in intensive care units. The complexity of the septic syndrome comprises immunological aspects- i.e.,sepsis induced immunosuppression- but is not restricted to this fact in modern concepts. So far, exact mechanisms and variables determining outcome and mortality stay unclear. Since there is no typical risk profile, early diagnosis and risk stratification remain difficult, which hinders rapid and effective treatment initiation. Due to the heterogeneous nature of sepsis, potential therapy options should be adapted to the individual. Biomarkers like C-reactive protein and procalcitonin are routinely used as complementary tools in clinical decision-making. Beyond the acute phase proteins, a wide bunch of promising substances and non-laboratory tools with potential diagnostic and prognostic value is under intensive investigation. So far, clinical decision just based on biomarker assessment is not yet feasible. However, biomarkers should be considered as a complementary approach. | Dubravka Kojic Benedikt H Siegler Florian Uhle Christoph Lichtenstern Peter P Nawroth Markus A Weigand Stefan Hofer Thorsten Brenner | 2015 | World Journal of Experimental Medicine2015，5，2： | 14 |
| 2 | Economic impact of minimally invasive lumbar surgery显示文摘Cost effectiveness has been demonstrated for traditional lumbar discectomy, lumbar laminectomy as well as for instrumented and noninstrumented arthrodesis. While emerging evidence suggests that minimally invasive spine surgery reduces morbidity, duration of hospitalization, and accelerates return to activites of daily living, data regarding cost effectiveness of these novel techniques is limited. The current study analyzes all available data on minimally invasive techniques for lumbar discectomy, decompression, short-segment fusion and deformity surgery. In general, minimallyinvasive spine procedures appear to hold promise in quicker patient recovery times and earlier return to work. Thus, minimally invasive lumbar spine surgery appears to have the potential to be a cost-effective intervention. Moreover, novel less invasive procedures are less destabilizing and may therefore be utilized in certain indications that traditionally required arthrodesis procedures. However, there is a lack of studies analyzing the economic impact of minimally invasive spine surgery. Future studies are necessary to confirm the durability and further define indications for minimally invasive lumbar spine procedures. | Christoph P Hofstetter Anna S Hofer Michael Y Wang | 2015 | World Journal of Orthopedics2015，6，2： | 4 |
| 3 | Platform-driven development of product families:linking theory with practice显示文摘 | HALMAN J I M HOFER A P VAN VUUREN W | 2003 | Journal of Product Innovation Management2003，20，2： | 1 |
| 4 | The potential of layout platforms for modular complex products and systems 显示文摘 | HOFER A P HALMAN J I M | 2005 | Journal of Engineering Design2005，16，2： | 1 |
| 5 | Use of Central Venous Catheter-Related Bloodstream Infection Prevention Pratices by US Hospital显示文摘 | Krein S L Hofer T P Kowalski C P | 2007 | Mayo Clin Proc2007，82，6： | 1 |
| 6 | hree year results of proximal tibia fractures treated with the LISS 显示文摘 | Boldin C Fankhauser F Hofer H P | 2006 | Clin Orthop Relat Res2006，445，4： | 1 |
| 7 | Microstructural Aspects on Creep Behaviour of Advanced Power Plant Steels 显示文摘 | Cerjak H Hofer P Schaffernak B | 2000 | Key Eng Mater2000，171，174： | 1 |
| 8 | Lipoxygenase inhibitors suppressproliferation of G5:113 fibrosarcoma cells in vetro but they no anticancer activity in vivo显示文摘 | Hoferova Z Fedorocko P Hofer M | 2003 | Neoplasma2003，50，2： | 1 |
| 9 | Analysis of the Dynamics in Microactuators Using High-Speed Cine Photomicrography显示文摘 | Rembe C Tibken B Hofer E P | 2001 | Journal of Microelectromechanical System2001，10，1： | 1 |
| 10 | Three-year results of proximal tibia fractures treated with LISS显示文摘 | Boldin C Fankhauser F Hofer H P | 2009 | Clin Orthop Relat Res2009，445，4： | 1 |
| 11 | Dynamic tyre forces response to road unevenness显示文摘 | Gipser M Hofer R Lugner P | 2007 | Vehicle System Dynamics2007，27，1： | 1 |
| 12 | Analysis of the dynamics in microactuators using high-speed cine photomicrography显示文摘 | Christian Rembe Bernd Tibken Eberhard P Hofer | 2001 | Journal of Microelectromechanical System2001，10，1： | 1 |
| 13 | Effects of interferon-alpha,verapamil and dacarbazine in the treatment of advanced malignant melanoma显示文摘 | Andersson R Ake Hofer P Riklund-Ahlstrom K | 2003 | Melanoma Res2003，13，1： | 1 |
| 14 | The potential of layout platforms for modular complex products and systems 显示文摘 | HOFER A P HALMAN J I M | 2005 | Journal of Engineering Design2005，16，2： | 1 |
| 15 | Appraisal of the Karnofsky Performance Status and proposal of a simple algorithmic system for its evaluation显示文摘 | Péus D Newcomb N Hofer S | | 0，，01： | 1 |
| 16 | The Development of Epistemologieal Theories: Beliefs About Knowledge and Knowing and Their Relation to Learning显示文摘 | Hofer B K Pintrich P R | 1997 | Review of Educational Research1997，67，1： | 1 |
| 17 | Toeotrienol and fatty acid composition of barley oil and their effects on lipid metabolism 显示文摘 | Linji Wang R K Newman C W Newman L L Jackson P J Hofer | 1993 | Plant Foods for Human Nutrition1993，43，： | 1 |
| 18 | Anaysis of the dynamics in microactuators using high-speed cinephotomicrography显示文摘 | Rembe C Tibken B Hofer E P | 2001 | J of MEMS2001，10，1： | 1 |
| 19 | The effect of periodontal therapy on the survival rate and incidence of complications of multirooted teeth with furcation involvement after an observation period of at least 5 years: a systematic review 显示文摘 | Huynh-Ba G Kuonen P Hofer D | 2009 | J Clin Periodontol2009，36，2： | 1 |
| 20 | The effect of periodontal therapy on the survival rate and incidence of complications of muhiroted teeth with furcation involvement after an observation period of at least 5 years a systematic review显示文摘 | Huynh-Ba G Kuonen P Hofer D et O1 | 2009 | J Clin Period- ontol2009，36，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员