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| 1 | Positive urinary antigen tests for Streptococcus pneumoniae in community-acquired pneumonia:a 7-year retrospective evaluation of health care cost and treatment consequences显示文摘 | Engel MF van Velzen M Hoepelman AI | | 0，，04： | 1 |
| 2 | Immune dysfunction in patients with diabetes mellitus (DM)显示文摘 | Geerlings SE Hoepelman AI | 1999 | FEMS Immunol Med Microhiol1999，26，： | 1 |
| 3 | Delayed HIVtesting in internal medicine clinics-a missed opportunity显示文摘 | Hermans L Wensing A Hoepelman A | 2012 | Neth JMed2012，70，2： | 1 |
| 4 | Effects of the capsular polysaccharides of Cryptococcus neoformans on phagocyte migration and inflammatory mediators显示文摘 | Ellerbroek PM Walenkamp AM Hoepelman AI | 2004 | Curr Med Chem2004，11，： | 1 |
| 5 | 早期将抗生素由静脉转为口服治疗严重社区获得性肺炎:多中心随机试验显示文摘目的比较早期由静脉转换成口服抗生素与常规静脉使用7天抗生素治疗严重社区获得性肺炎(CAP)的疗效。设计多中心随机对照试验。地点荷兰5家教学医院和2所大学的医学中心。参加者非 ICU 住院的严重 CAP 患者302例,其中265例满足研究要求。干预静脉抗生素治疗3天,病情稳定后换成口服抗生素,或静脉使用抗生素治疗7天。主要评价结果临床治愈和住院天数。结果 302例患者被随机分组(平均年龄69.5岁,标准差14.0),肺炎严重度评分平均112.7(26.0)。37例患者因为提前3天退出而未纳入分析,对其余265例患者进行分析研究。第28天的死亡率在干预组是4%,对照组是6%(平均差2%,95%可信区间-3%~8%)。临床治愈率在干预组是83%,对照组是85%(2%;-7%~10%)。与对照组相比,干预组患者静脉治疗时间为3.4天[3.6(1.5)比7.0(2.0)天;2.8~3.9],患者住院天数减少1.9天[9.6(5.0)比11.5(4.9)天;0.6~3.2]。结论早期将抗生素由静脉应用转换成口服治疗严重 CAP 是安全的,并且可以减少住院时间2天。试验注册号临床试验 NCT00273676。 | Jan Jelrik Oosterheert Marc J M Bonten Margriet M E Schneider Erik Buskens Jan-Willem J Lammers Willem M N Hustinx Mark H H Kramer Jan M Prins Peter H Th J Slee Karin Kaasjager Andy I M Hoepelman 王伟巍(译) 童朝辉(校) | 2007 | 英国医学杂志中文版2007，10，2： | 1 |
| 6 | Effects of the capsular polysaccharides of Cryptococcus neoformans on phagocyte migration and inflammatory mediators显示文摘 | Ellerbroek PM Walenkamp AM Hoepelman AI | 2004 | Current Medical Chemistry2004，11，2： | 1 |
| 7 | Consequences of microbial attchment:Directing host cell functionis with adhesions显示文摘 | Hoepelman AM Tuomanen EI | 1992 | Infcet Immun1992，60，5： | 1 |
| 8 | A sh- ort (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxi- clav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome显示文摘 | Hoepelman IM Mailers M J van Schie MH | 1997 | Int J Antimicrob Agents1997，9，3： | 1 |
| 9 | Risk Factors for symptomatic urinary tract infection in women with diabetes 显示文摘 | Geerlings SE Stolk RP Hoepelman AI | 2000 | Diabetes Care2000，23，12： | 1 |
| 10 | Effects of the capsular polysaccharides of Cryptococcus neoformans on phagocyte migration and inflammatory mediators显示文摘 | Ellerbroek P M Walenkamp A M Hoepelman A I | 2004 | Curt Med Chem2004，11，2： | 1 |
| 11 | Immune dysfunction in patients with diabetes mellitus (DM)显示文摘 | Geerlings SE Hoepelman AI | 1999 | FEMS Immunol Med Microbiol1999，26，： | 1 |
| 12 | Management of bacterial urinary tract infections in adult patients with dibetes mellitus显示文摘 | Mezland R Geerlings S E Hoepelman A I | | 0，，13： | 1 |
| 13 | A single blind comparison of three day azithromycin and ten day co-amoxiclacv treatment of acute lower respiratory tract infections显示文摘 | Sips AP van Helmond JLM | 1993 | J Antimicrob chemother1993，31，： | 1 |
| 14 | Pathogenesis and management of bacterial urinary tract infections in adult patients with diabetes melli tus 显示文摘 | Hoepelman AI Meiland R Geerlings SE | 2003 | Int J Antimicrobial Agents2003，22，1： | 1 |
| 15 | Management of bacterial urinary tract infections in adult patients with diabetes mellitus 显示文摘 | MEILAND R GEERLINGS SE HOEPELMAN A I | 2002 | Drugs2002，62，： | 1 |
| 16 | Management of bacterial wrinary tract infections in adult patients with diabetes mellitus显示文摘 | Geerlings SE Hoepelman AI | 2002 | Drags2002，62，： | 1 |
| 17 | Mannose binding lectin plays a crucial role in innate immunity a gainst yeast by enhanced complement activation and enhanced uptake of polymorphonuclear cells 显示文摘 | van Asbeck EC Hoepelman AI Scharringa J etal | 2008 | BMC Microbiol2008，8，： | 1 |
| 18 | Management of bacterial urinary tract infections in adult patients with dibetes mellitus 显示文摘 | MEZLAND R GEERLINGA SE HOEPELMAN A I | 2002 | Drugs2002，62，： | 1 |
| 19 | Mannose binding lectin plays a crucial role in innate immunity against yeast by enhanced complement activation and enhanced uptake of polymorphonuclear cells显示文摘 | van Asbeck EC Hoepelman AI Scharringa J | 2008 | BMC Microbiol2008，8，： | 1 |
| 20 | Immune dysfunction in patients with dia-betes mellitus(DM)显示文摘 | Geerlings SE Hoepelman AI | 1999 | FEMS Immunol Med Microbiol1999，26，34： | 1 |
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