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| 1 | Evidence of endometrial amino acid metabolism and transport modulation by peri-ovulatory endocrine profiles driving uterine receptivity显示文摘Background: In beef cattle, changes in the periovulatory endocrine milieu are associated with fertility and conceptus growth. A large preovulatory follicle(POF) and the resulting elevated concentrations of progesterone(P4) during diestrus positively affect pregnancy rates. Amino acids(AA) are important components of maternally derived secretions that are crucial for embryonic survival before implantation. The hypothesis is that the size of the POF and the concentration of P4 in early diestrus modulate the endometrial abundance of SLC transcripts related to AA transport and metabolism and subsequently impact luminal concentrations of AA. The follicle growth of Nelore cows was manipulated to produce two experimental groups: large POF and CL(LF-LCL group) and small POF and CL(SF-SCL group). On Day 4(D4; Experiment 1) and Day 7(D7; Experiment 2) after Gn RH-induced ovulation(Gn RH treatment = D0), the animals were slaughtered and uterine tissues and uterine washings were collected. q RT-PCR was used to evaluate the expression levels of AA transporters in D4 and D7 endometrial tissues.The concentrations of AA were quantified in D4 and D7 uterine washings by HPLC.Results: Transcript results show that, on D4, SLC6 A6, SLC7 A4, SLC17 A5, SLC38 A1, SLC38 A7 and SCLY and on D7 SLC1 A4, SLC6 A1, SLC6 A14, SLC7 A4, SLC7 A7, SLC7 A8, SLC17 A5, SLC38 A1, SLC38 A7, SLC43 A2 and DDO were more abundant in the endometria of cows from the LF-LCL group(P < 0.05). In addition, concentrations of AA in the uterine lumen were influenced by the endocrine profiles of the mother. In this context, D4 uterine washings revealed that greater concentrations of taurine, alanine and α-aminobutyric acid were present in SF-SCL(P < 0.05).In contrast, lower concentrations of valine and cystathionine were quantified on D7 uterine washings from SF-SCL cows(P < 0.05).Conclusion: The present study revealed an association between the abundance of transcripts related to AA transport and metabolism in the endometrium and specific periovulatory endocrine profiles related to the receptive status of the mother. Such insights suggest that AAs are involved in uterine function to support embryo development. | Moana Rodrigues Franca Maressa Izabel Santos da Silva Guilherme Pugliesi Veerle Van Hoeck Mario Binelli | 2017 | Journal of Animal Science and Biotechnology2017，8，4： | 4 |
| 2 | 熔融混合工艺对原位复合材料力学性能的影响显示文摘为了实验研究熔融混合工艺对原位复合材料力学性能的影响,采用两种不同结构的螺杆制备了不同热致液晶高分子含量的原位复合材料.发现不同的螺杆结构混合并不能对复合材料的力学性能造成明显的影响.原位复合材料的回收使用性能良好,反复加工对力学性能变化的影响很小,而对玻璃纤维增强的材料,将造成性能衰减.对原位复合材料最终一次的加工工艺决定了材料的最后性能. | 益小苏 Hoeck,P | 1995 | 浙江大学学报(自然科学版)1995，29，3： | 2 |
| 3 | Analysis of benzophenone and 4-methylbenzophenone in breakfast cereals using ultrasonic extraction in combination with gas chromatography-tandem mass spectrometry (GC-MSn) 显示文摘 | Van Hoeck E De Schaetzen T Pacquet C | 2010 | Analytica Chimica Acta2010，663，： | 1 |
| 4 | Elevated non-esterified fatty acid concentrations during bo- vine oocyte maturation compromise early embryo physiology 显示文摘 | Van Hoeck V Sturmey RG Bermejo-Alvarez P | 2011 | PLoSOne2011，6，23： | 1 |
| 5 | Microwear of mammalian teeth as an indicator of diet显示文摘 | Walker A Hoeck H Perez L | | 0，，4359： | 1 |
| 6 | Evidence of HIF-1 functional binding activity to Caspase 3 promoter after photo thrombotic cerebral ischemia显示文摘 | Van Hoecke M Prigent Tessier AS Garnier PE | 2007 | Mol Cell Neurosci2007，34，1： | 1 |
| 7 | Psychological and psychiatric issues in urinary and fecalincontinence显示文摘 | von Gontard A Baeyens D Van Hoecke E | 2011 | J Urol2011，185，4： | 1 |
| 8 | Molecular marker analysis of seed size in soybean显示文摘 | Hoeck J A W R Fehr R C Shoemaker | 2003 | Crop Science2003，43，： | 1 |
| 9 | Are pulmonary homograft which were subjected to pulmonary hypertension more appropriate for aortic valve replacement than normal pulmonary homograft? A long-term multicentric echography study显示文摘 | Jashari R van Hoeck B Gaudino M | 2000 | Eur J Cardiothorac Surg2000，17，： | 1 |
| 10 | Problem behavior,parental stress and enuresis显示文摘 | De Bruyne E Van Hoecke E Van Gompel K | | 0，，4： | 1 |
| 11 | Towards automated, miniaturized and solvent-free sample preparation methods显示文摘 | David E Van Hoeck E Sandra P | 2007 | Anal Bioanal Chem2007，387，： | 1 |
| 12 | Pyruvate protects against experimental stroke via an anti-inflammatory mechanism显示文摘 | Wang Q van Hoecke M Tang X N | | 0，，01： | 1 |
| 13 | Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2'-dipyridyl显示文摘 | Van Hoecke M Prigent-Tessier A Bertrand N | 2005 | Eur J Neurosci2005，22，5： | 1 |
| 14 | Part logistics in the automotiveindustry: Decision problems, literature review and researchagenda显示文摘 | BOYSEN N EMDE S HOECK M | 2015 | European Journal of Operational Research2015，242，10： | 1 |
| 15 | Evaluation of two new automated chemiluminescent assays (HemosIL AcuStar HIT-IgG and HemosIL AcuStar HIT-Ab) for the detection of heparin-induced antibodies in the diagnosis of heparin-induced thrombocytopenia 显示文摘 | Van Hoecke F Devreese K | 2012 | IntJ Lab Hematot2012，34，4： | 1 |
| 16 | Banking of cryopreserved heart valves in Europe:assessment of alO - year operation in the Euro- pean Homograft Bank (EHB) 显示文摘 | Goffin YA Van Hoeck B Jashari R | 2000 | J Heart Valve Dis2000，9，2： | 1 |
| 17 | Evaluation of two new automated chemiluminescent assays (HemoslL AcuStar HIT-IgG and HemosIL AcuStar HIT-Ab) for the detection of heparin-induced antibodies in the diagnosis of heparin-induced thrombocytopenia 显示文摘 | Van Hoecke F Devreese K | 2012 | IntJ Lab Hematot2012，34，4： | 1 |
| 18 | Viamin D status and its relationship with bone mineral density and parathy- roid hormone in southeast Asian adults with low bone density显示文摘 | CHANDRAN M HOECK H C WONG H C | 2011 | endocr Praet2011，17，2： | 1 |
| 19 | Fate and effects of CeO2 nanoparticles in aquatic ecotoxicity tests显示文摘 | Van Hoecke K Quick J.T.K Mankiewicz-Boczek J De Schamphelaere A van der Meeren P Barnes C. | | 0，，： | 1 |
| 20 | Psychologi- cal and psychiatric issues in urinary and fecal incontinence 显示文摘 | Von Gontard A Baeyens D van Hoecke E | 2011 | J Urol2011，185，4： | 1 |
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