|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Laser sintering of Bi4Ti3O12 ferroelectric ceramics 显示文摘 | MACEDO Z S HERNANDES A C | 2002 | Mater Lett2002，55，： | 2 |
| 2 | Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features显示文摘AIM To investigate the association between 16 insertiondeletions(INDEL) polymorphisms, colorectal cancer(CRC) risk and clinical features in an admixed population.METHODS O n e h u n d re d a n d fo r ty p a t i e n t s w i t h C R C a n d 140 cancer-free subjects were examined. Genomic DNA was extracted from peripheral blood samples. Polymorphisms and genomic ancestry distribution were assayed by Multiplex-PCR reaction, separated by capillary electrophoresis on the ABI 3130 Genetic Analyzer instrument and analyzed on Gene Mapper ID v3.2. Clinicopathological data were obtained by consulting the patients' clinical charts, intra-operative documentation, and pathology scoring.RESULTS Logistic regression analysis showed that polymorphism variations in IL4 gene was associated with increased CRC risk, while TYMS and UCP2 genes were associated with decreased risk. Reference to anatomical localization of tumor Del allele of NFKB1 and CASP8 were associated with more colon related incidents than rectosigmoid. In relation to the INDEL association with tumor node metastasis(TNM) stage risk, the Ins alleles of ACE, HLAG and TP53(6 bp INDEL) were associated with higher TNM stage. Furthermore, regarding INDEL association with relapse risk, the Ins alleles of ACE, HLAG, and UGT1A1 were associated with early relapse risk, as well as the Del allele of TYMS. Regarding INDEL association with death risk before 10 years, the Ins allele of SGSM3 and UGT1A1 were associated with death risk.CONCLUSION The INDEL variations in ACE, UCP2, TYMS, IL4, NFKB1, CASP8, TP53, HLAG, UGT1A1, and SGSM3 were associated with CRC risk and clinical features in an admixed population. These data suggest that this cancer panel might be useful as a complementary tool for better clinical management, and more studies need to be conducted to confirm these findings. | Diego Marques Layse Raynara Ferreira-Costa Lorenna Larissa Ferreira-Costa Romualdo da Silva Correa Aline Maciel Pinheiro Borges Fernanda Ribeiro Ito Carlos Cesar de Oliveira Ramos Raul Hernandes Bortolin André Ducati Luchessi Andrea Ribeiro-dos-Santos Sidney Santos Vivian Nogueira Silbiger | 2017 | World Journal of Gastroenterology2017，23，37： | 2 |
| 3 | Microstructural, structural and electrical properties of La 3+ -modified Bi 4 Ti 3 O 12 ferroelectric ceramics显示文摘 | V.B. Santos J.-C. M’Peko M. Mir V.R. Mastelaro A.C. Hernandes | 2008 | Journal of the European Ceramic Society2008，，4： | 2 |
| 4 | TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionarylineage of enteropathogenic Escherichia coli 显示文摘 | Whale AD Hernandes RT Ooka T | 2007 | Microbiology2007，153，： | 1 |
| 5 | High pressure and tempreture effects on enzyme inactivation in tomato puree显示文摘 | Hernandes A Cano M P | 1998 | J Agric Food Chem1998，46，： | 1 |
| 6 | 查看详情显示文摘 | Santos C N Menses D D S Echegut P Neuville D R Hernandes A C Ibanez A | | 0，，： | 1 |
| 7 | Glycine as a neurotransmitter in the forebrain:a short review显示文摘 | Hernands M S Troncone L R P | 2009 | J Neural Transm2009，116，： | 1 |
| 8 | Statistical genetic considerations for maintaining germ plasm collections显示文摘 | Crossa J Hernandes C M Bretting P | 1993 | Theor Appl Genet1993，86，： | 1 |
| 9 | Antioxidant systems and02_/H202 production in the apoplast of pea leaves: ts relation with salt-induced necrotic lesions in minor veins 显示文摘 | Hernande J A Ferrer M A Jimenez A | 2001 | Plant Physiol2001，127，： | 1 |
| 10 | Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation显示文摘 | HAGUE S ROGAEVA E HERNANDE ZD | 2003 | Ann Neurol2003，54，2： | 1 |
| 11 | High pressure and tempreture effects on enzyme inactivation in tomato puree显示文摘 | Hernandes A Cano M P | 1998 | J Agric Food Chem1998，46，： | 1 |
| 12 | Microglial cellsare involved in the susceptibility of NADPH oxidase knockout mice to6-hydroxy-dopamine-induced neurodegeneration 显示文摘 | Hernandes MS Santos GDR Café-Mendes CC | 2013 | Plo S one2013，8，75： | 1 |
| 13 | Third-order nonlinear spectra and optical limiting of lead oxifluoroborate glasses 显示文摘 | ALMEIDA J M P BONI L D HERNANDES A C | 2011 | Opt Express2011，19，17： | 1 |
| 14 | Laser sintering of Bi4Ti3O12 ferroelectric ceramics显示文摘 | Macedo Z S Hernandes A C | 2002 | Mater Lett2002，55，4： | 1 |
| 15 | Densitometry, radiography, and histological assessment of collagen as methods to evaluate femoral bones in an experimental model of osteoporosis 显示文摘 | Hernandes L Micheletti KR Santi AP | 2012 | Osteoporos2012，23，2： | 1 |
| 16 | Alligator Metabolism显示文摘 | Coulson RA Hernande T | 1983 | J Comp Biochem Physiol1983，，： | 1 |
| 17 | Predictors of poor renal outcome in patients with lupus nephritis treated with combined pulses of cyclophosphamide and methylprednisolone 显示文摘 | Cortes- Hernandes J Ordi - Ros J Labrador M | 2003 | Lupus2003，12，4： | 1 |
| 18 | Laser sintering of Bi4Ti3O12ferroelectric ceramics显示文摘 | Macedo Z S Hernandes A C | 2002 | Materials Letters2002，55，4： | 1 |
| 19 | Mechanical and thermal properties of novel polymerized NDGA-gelatin hydrogels显示文摘 | Koob TJ Daniel J Hernande Z | 2003 | Biomaterials2003，24，： | 1 |
| 20 | Exercise-induced plasticity of AMPAtype glutamate receptor subunits in the rat brain显示文摘 | Real CC Ferreira AF Hernandes MS Britto LR Pires RS | 2010 | Brain Res2010，1363，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员