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| 1 | On the Function of Wall Sculpturing in Xylem Conduits显示文摘The water-conducting network of capillaries in vascular plants has evolved over hundreds of millions of years in order to beable to cope with bubble clogging,a problem which also affects modern microfluidic devices.Decades of anatomical studieshave revealed that plants growing in habitats in which the formation of bubbles,or emboli,is likely to be a frequent occurrenceoften have various forms of geometrical sculpturing on the internal surfaces of the xylem conduits.The possible function of suchwall sculpturing has long been the subject of speculation.We have investigated the hypothesis that wall sculpturing is a functionaladaptation designed to increase the wettability of the walls of xylem conduits,an effect which could be described as theinverse of the well-known lotus-effect.Our results show that wall sculpturing does enhance wettability.Importantly,theoreticalcalculations reveal that the geometric parameters of various types of wall sculpturing are such that the resulting surfaces aresufficiently rough to enhance wettability,but not significantly rougher.The results provide an appealing answer to thelong-standing debate on the function of wall sculpturing in xylem conduits,and may provide biomimetic clues for new approachesto the removal of bubbles in microfluidic channels. | Mika M.Kohonen se Helland | 2009 | Journal of Bionic Engineering2009，6，4： | 6 |
| 2 | 消痈溃得康及其拆方预防乙醇致大鼠急性胃黏膜损伤的抗氧化机制显示文摘目的:探讨消痈溃得康及其拆方对乙醇致大鼠急性胃黏膜损伤的保护作用及机制。方法:将48只Wistar大鼠随机分为正常组、模型组、消痈溃得康组、清热解毒组、和血止血组、托里生肌组。给药组连续给药5天,末次给药1 h后,模型组和给药组灌胃1 m L无水乙醇,作用1 h,造成大鼠急性胃黏膜损伤。以大体及光镜下观察评价消痈溃得康及其拆方对胃黏膜损伤的保护作用;采用生化检测法检测胃组织中谷胱甘肽(Glutathione,GSH)含量、脂质过氧化物(Lipid Peroxide,LPO)含量以及诱导型一氧化氮合酶(Inducible Nitric Oxide Synthase,i NOS)活力的变化。结果:消痈溃得康及各拆方组溃疡指数明显低于模型组(P<0.01),给药组与模型组比较大鼠胃组织中GSH含量明显高于模型组(P<0.01),LPO含量明显低于模型组(P<0.01),i NOS酶活力明显低于模型组(P<0.01)。结论:消痈溃得康对乙醇诱导的大鼠急性胃损伤具有明显的保护作用,其中消痈溃得康组和清热解毒组药物作用最为明显,提示乙醇诱导的大鼠急性胃损伤符合中医毒热证证型,消痈溃得康及各拆方对其保护作用的机制可能与抗氧化有关。 | 董文秀 才丽平 花梦 李宁 孙云峰 蒋宁 Timothy Helland 林庶茹 郑洪新 周学文 | 2016 | 世界科学技术-中医药现代化2016，18，12： | 2 |
| 3 | On the Structure of Partial Least Squares Regression显示文摘 | Helland I S | 1988 | Communications in statistics1988，17，2： | 1 |
| 4 | Location, sided- ness, and sex distribution of intracranial arachnoid cysts in a population-based sample 显示文摘 | Helland CA Lund-Johansen M Wester K | 2010 | J Neurosurg2010，113，5： | 1 |
| 5 | Corporate Philanthropic Practices显示文摘 | Brown W.O Helland E Smith J.K | | 0，，05： | 1 |
| 6 | Deregulation of MY-CN,LIN28B and LET7 in a molecular subtype of aggressivehigh-grade serous ovarian cancers显示文摘 | Tan P Helland A Anglesio MS | 2011 | PLoS One2011，6，4： | 1 |
| 7 | Institutionalizing a broader view of scholarship through Boyer's four domains显示文摘 | Braxton J M Luckey W Helland P | 2002 | ASHE-ERIC Higher Education Report2002，29，2： | 1 |
| 8 | Mutations in the P53 gene and protein expression of P53, MDM2 and P21waf1/cip1 in primary cervical carcinomas with no or low human papillomavirus load显示文摘 | Helland A Karlsen F Due EU | 1998 | Br J Cancer1998，78，1： | 1 |
| 9 | Experiments on the transition of homogenous turbulence to internal waves in a stratified fluid 显示文摘 | STILLINGER D C HELLAND K N VON ATTA C W | 1983 | Journal of Fluid Mechanics1983，131，： | 1 |
| 10 | Stratigraphic base level and fluvial architecture Ericson sandstone(Campanian),rock springs uplift,SW Wyoming USA显示文摘 | Martinsen O J Ryseth A Helland Hansen W | 1999 | Sedimentology1999，46，2： | 1 |
| 11 | Recursive algorithm for partial least squares regression显示文摘 | Helland K Berntsen H E Borgen O S | 1992 | Chemometrics and Intelligent Laboratory Systems1992，14，13： | 1 |
| 12 | Allelic imbalance at chromosome region 11q23 in cervical carcinomas显示文摘 | Skomedal H Helland A Kristensen GB | 1999 | Eur J Cancer1999，35，4： | 1 |
| 13 | Benzyl-penicillin ( Penicillin G) transformation in aqueous solution at low temperature under controlled laboratory conditions 显示文摘 | BERGHEIM M HELLAND T KALLENBORN R | 2010 | Chemosphere2010，81，11： | 1 |
| 14 | Service life prediction of existing concrete structures exposed to marine environment显示文摘 | Maage M Helland S | 1996 | ACI Materials Journal1996，93，6： | 1 |
| 15 | Chemical characterization and functional properties of a potato protein concentrate prepared by large-scale expanded bed adsorption chromatography显示文摘 | Sissel Lkra Merete H Helland Ingrid C Claussen | 2008 | LWT-Food Science and Technology2008，41，6： | 1 |
| 16 | Immunohistochemical analysis of P53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri显示文摘 | Holm R Skomedal H Helland A | 1993 | J Pathol1993，169，1： | 1 |
| 17 | Growth and decay of turbulence in a stably stratified shear flow显示文摘 | ROHR J J ITSWEIRE E C HELLAND K N VON ATTA C W | 1988 | Journal of Fluid Mechanics1988，195，： | 1 |
| 18 | Intracystic pressure in patients with temporal arachnoid cysts: a prospective study of preopera- tive complaints and postoperative outcome 显示文摘 | Helland CA Wester K | 2007 | J Neurol Neurosurg Psychiatry2007，78，6： | 1 |
| 19 | Synthesis of 4-phenylpyrimidine from acetophenone and formamide显示文摘 | Tore Lejon | 1999 | Heterocycles1999，51，3： | 1 |
| 20 | External fixation versus locked intramedullary nailing in tibial shaft fractures:a prospective, randomised study of 78 patients 显示文摘 | Braten M Helland P Grontvedt T | 2005 | Arch Orthop Trauma Surg2005，1，： | 1 |
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