|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets显示文摘AIM: To investigate the effect of protein-energy malnutrition on intestinal barrier function during rotavirus enteritis in a piglet model.METHODS: Newborn piglets were allotted at day 4 of age to the following treatments:(1) full-strength formula(FSF)/noninfected;(2) FSF/rotavirus infected;(3) half-strength formula(HSF)/noninfected;or(4) HSF/rotavirus infected.After one day of adjustment to the feeding rates,pigs were infected with rotavirus and acute effects on growth and diarrhea were monitored for 3 d and jejunal samples were collected for Ussingchamber analyses.RESULTS: Piglets that were malnourished or infected had lower body weights on days 2 and 3 post-infection(P < 0.05).Three days post-infection,marked diarrhea and weight loss were accompanied by sharp reductions in villus height(59%) and lactase activity(91%) and increased crypt depth(21%) in infected compared with non-infected pigs(P < 0.05).Malnutrition also increased crypt depth(21%) compared to full-fed piglets.Villus:crypt ratio was reduced(67%) with viral infection.There was a trend for reduction in transepithelial electrical resistance with rotavirus infection and malnutrition(P = 0.1).3H-mannitol flux was significantly increased(50%;P < 0.001) in rotavirus-infected piglets compared to non-infected piglets,but there was no effect of nutritional status.Furthermore,rotavirus infection reduced localization of the tight junction protein,occludin,in the cell membrane and increased localization in the cytosol.CONCLUSION: Overall,malnutrition had no additive effects to rotavirus infection on intestinal barrier function at day 3 post-infection in a neonatal piglet model. | Sheila K Jacobi Adam J Moeser Anthony T Blikslager J Marc Rhoads Benjamin A Corl Robert J Harrell Jack Odle | 2013 | World Journal of Gastroenterology2013，19，31： | 4 |
| 2 | Impact of 'adverse selection' on managers project evaluation decisions 显示文摘 | HARRISON P D HARREL A | 1993 | Academy of Management Journal1993，36，3： | 1 |
| 3 | National survey of physicians' perception of the cause, complications, and management of gastroparesis显示文摘 | Briley LC Harrell SP Woosley A | 2011 | South Med J2011，104，6： | 1 |
| 4 | Comnmnication networks - the hidden organizational clum 显示文摘 | HARRELL A T | 1976 | The Personal Administrator1976，21，6： | 1 |
| 5 | Service recovery : Impactsatisfaction and intentions 显示文摘 | Spreng R A Harrell G D Mackoy R D | 1995 | Journal of Service Marketing1995，9，1： | 1 |
| 6 | Germline transponmation of Drosophilia melanogaster with the piggyBac transposon vector显示文摘 | HANDLER A M HARRELL II R A | 1999 | Insect Mol Biol1999，8，4： | 1 |
| 7 | Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus显示文摘 | Corl B A Harrell R J Moon H K | 2007 | J Nutr Bio2007，18，： | 1 |
| 8 | Sensitivity of ERS-1 and JERS-1 radar data to biomass and stand structure in Alaskan forest显示文摘 | Harrell P A Bourgeau-Chavez L L Kasischke E | 1995 | Remote Sensing of Environment1995，54，： | 1 |
| 9 | The impact of adverse selection' on managers' project evaluation decisions显示文摘 | Harrison P Harrell A | 1993 | Academy of Management Journal1993，，36： | 1 |
| 10 | Differential diagnosis of acute meningitis:an analysis of the predictive value of initial observations显示文摘 | Spanos A Harrell FE Jr Durack DT | 1989 | JAMA1989，262，： | 1 |
| 11 | An end-effector for robotic removal of citrus from the tree显示文摘 | Pool T A Harrell R C | 1991 | Transactions of the ASAE1991，34，2： | 1 |
| 12 | Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis显示文摘 | Harrell MI Iritani BM Ruddell A | 2007 | Am J Pathol2007，170，2： | 1 |
| 13 | Sensitivity of ERS - 1 and YEBS - 1 Radar data to biomass and stand structure in Alaskan boreal forest 显示文摘 | P A Harrell L L Bourgesu Chavez | 1995 | Remote Sensing of Environment1995，54，： | 1 |
| 14 | Polyaniline/Single-walled Carbon Nanotube Composite Electronic Devices显示文摘 | Ramamurthy P C Malshe A M Harrell W R | 2004 | Solid-state Electronics2004，48，： | 1 |
| 15 | Leisure time activities of elementary school children显示文摘 | HARRELL J S GANSKY S A BRADLWY C B | 1997 | Nurs Res1997，46，5： | 1 |
| 16 | Intestinal ribosomal p70 (S6K) signaling is increased in piglet rotavirus enteritis显示文摘 | RHOADS J M CORL B A HARRELL R | 2007 | American Journal of Physiology:Gastrointestinal and Liver Physiology2007，292，3： | 1 |
| 17 | Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus显示文摘 | Corl B A Harrell R J Moon H K | 2007 | The Journal of Nutritional Biochemistry2007，18，12： | 1 |
| 18 | Impact of Adverse Selection on Managers Project Evaluation Decisions 显示文摘 | Harrison P D Harrel A | 1993 | Academy of Management Journal1993，36，3： | 1 |
| 19 | Vertical transmission of channel catfish virus显示文摘 | Wise J A Harrell S F Busch R L | 1988 | Am J Vet Res1988，49，9： | 1 |
| 20 | Variation in lipid and fatty acid contents of Atlantic croakers,striped mullet and summer flounder显示文摘 | Gallagher M L Harrell M L Rulifson R A | 1991 | Transactions of the American Fisheries Society1991，120，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员