|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment显示文摘Pharmaceuticals and personal care products(PPCPs)are a unique group of emerging environmental contaminants,due to their inherent ability to induce physiological effects in human at low doses.An increasing number of studies has confirmed the presence of various PPCPs in different environmental compartments,which raises concerns about the potential adverse effects to humans and wildlife.Therefore,this article reviews the current state-of-knowledge on PPCPs in the freshwater aquatic environment.The environmental risk posed by these contaminants is evaluated in light of the persistence,bioaccumulation and toxicity criteria.Available literature on the sources,transport and degradation of PPCPs in the aquatic environment are evaluated,followed by a comprehensive review of the reported concentrations of different PPCP groups in the freshwater aquatic environment(water,sediment and biota)of the five continents.Finally,future perspectives for research on PPCPs in the freshwater aquatic environment are discussed in light of the identified research gaps in current knowledge. | Anekwe Jennifer Ebele Mohamed Abou-Elwafa Abdallah Stuart Harrad | 2017 | Emerging Contaminants2017，3，1： | 44 |
| 2 | Occurrence,seasonal variation and human exposure to pharmaceuticals and personal care products in surface water,groundwater and drinking water in Lagos State,Nigeria显示文摘The occurrence of 28 pharmaceuticals and personal care products(PPCPs)was investigated in 17 surface water samples(rivers,canals,and lagoons),12 groundwater samples(wells and boreholes,which can also be consumed for drinking)and 8 drinking water samples(bottles and sachets)during dry and rainy seasons in Lagos state,Nigeria.The most prevalent compound detected in all samples was amoxicillin(an antibiotic)at median concentrations of 1614,238 and 358 ng/L in surface water,ground water and drinking water,respectively.This is of concern due to potential impact on development of antibioticresistant microbial strains.Other frequently-detected compounds include acetaminophen,nicotine,ibuprofen,and codeine with detection frequencies of more than 70%.Investigation of seasonal variability revealed that glyburide,caffeine,naproxen and diclofenac concentrations were significantly(P<0.05)higher during the dry season(winter),while Nicotine and Codeine levels were higher during the rainy season(summer).The factors influencing such seasonal variability include:dilution by extensive rainfall,agricultural activity(for nicotine)and usage patterns of pharmaceuticals among the local community.Measured concentrations in drinking water samples were used to assess inadvertent human exposure to PPCPs in Nigerian adults.Results revealed average daily exposures of 81,14 and 3 ngƩPPCPs/kg BW/day via drinking borehole,sachet water and bottled water,respectively.While there exists no health-based limit value(HBLV)for chronic exposure to mixtures of PPCPs,our results raise concern and warrant further investigation of the potential health implications of such unintended PPCPs exposure. | Anekwe Jennifer Ebele Temilola Oluseyi Daniel S.Drage Stuart Harrad Mohamed Abou-Elwafa Abdallah | 2020 | Emerging Contaminants2020，6，1： | 4 |
| 3 | Concentrations of organophosphate flame retardants in dust from cars, homes, and offices: An international comparison显示文摘Concentrations of a number of organophosphate flame retardants(PFRs)were measured in floor dust collected from living rooms in Australia(n=42),Canada(n=14),Germany(n=22),and Kazakhstan(n=9);cars from Australia(n=39)and Germany(n=19);and offices from Germany(n=25)and Kazahkstan(n=8).PFR concentrations in these samples were compared with each other and with previously reported data for PFRs in dust from similar microenvironments in the UK.Our data reveal significant between-country differences in both absolute concentrations and the relative abundance of specific PFRs in each of the microenvironments studied.Most notably,concentrations of TCIPP in UK living room dust(median=21 μg g^-1)exceeded significantly(p<0.05)those in all other countries studied here;a substantial number of car dust samples contained elevated concentrations of TDCIPP,and German samples generally contained lower levels of PFRs in all microenvironments studied.In addition,PFRs were determined in dust samples collected from living room couches in both Australia(n=41)and the UK(n=10).The elevated concentrations of TCIPP in UK living room dust are likely attributable to the favoured use of this PFR in UK couch foam.This is indicated by concentrations of TCIPP in UK couch dust(median=610 μg g^-1)exceeding significantly those in Australian couch dust(median=2.9 μg g^-1).Moreover,concentrations of TCIPP in UK couch dust originating from couches 15 years old or less,display a marked relationship with the age of the couch,with concentrations in such samples increasing significantly(p<0.01)with couch age. | Stuart Harrad Sandra Brommer Jochen F.Mueller | 2016 | Emerging Contaminants2016，2，2： | 3 |
| 4 | Hexabromocyclododecane and tetrabromobisphenol-A in indoor dust from France, Kazakhstan and Nigeria: Implications for human exposure显示文摘Concentrations of hexabromocyclododecane isomers(α-,β-and γ-HBCDs)and tetrabromobisphenol-A(TBBP-A)were measured-for the first time-in indoor dust from homes,offices and cars from France,Kazakhstan and Nigeria.∑HBCDs in French and Kazakhstani house dust(median=1351 and 280 ng g^-1,respectively)were consistent with previous reports from the UK and Romania,respectively.Concentrations of ∑HBCDs in Nigerian domestic dust(median=394 ng g^-1)were substantially higher than those reported from Egyptian homes.In general,concentrations of ∑HBCDs in the studied microenvironments were higher than those of TBBP-A,which may be attributed to the major application of TBBP-A as a reactive flame retardant;rendering its release to dust more difficult.Statistical analysis revealed significantly lower ∑HBCDs in French houses than those found in both offices and cars,while ∑HBCDs in cars from Kazakhstan were higher(P<0.05)than those in homes and offices.Moreover,TBBP-A concentrations in car dust from Nigeria were lower than those found in homes and offices.Exposure estimates revealed higher intake of HBCDs and TBBP-A by toddlers via indoor dust ingestion compared to adults.Combined with their low body weight,this can raise concerns over the potential adverse health effects of such high exposure in toddlers. | Mohamed Abou-Elwafa Abdallah Michael Bressi Temilola Oluseyi Stuart Harrad | 2016 | Emerging Contaminants2016，2，2： | 2 |
| 5 | Polybrominated diphenyl ethers and“novel”brominated flame retardants in floor and elevated surface house dust from Iraq:Implications for human exposure assessment显示文摘Concentrations of polybrominated diphenyl ethers(PBDEs)and selected novel brominated flame retardants(NBFRs)were measured in indoor dust from the living areas of 18 homes in Basrah,Iraq.This is the first report of contamination of the Iraqi environment with these chemicals.To evaluate the implications for human exposure,samples were collected from both the floor and from elevated surfaces like tables,shelves and chairs.When normalised for the organic carbon content of the dust sample,concentrations in elevated surface dust of BDE-99,BDE-209,pentabromoethylbenzene(PBEB),bis(2-ethylhexyl)3,4,5,6-tetrabromophthalate(BEH-TEBP),and decabromodiphenylethane(DBDPE)exceeded significantly(p<0.05)those in floor dust from the same rooms.This suggests that previous studies that base estimates of adult exposure via dust ingestion on floor dust,may underestimate exposure.Such underestimation is less likely for toddlers who are far more likely to ingest floor dust.Concentrations of PBDEs and NBFRs in indoor dust from Basrah,Iraq are at the lower end of levels reported elsewhere.The PBDE contamination pattern in our samples suggests that use in Iraq of the Deca-BDE formulation,exceeds substantially that of Penta-BDE,but that use of the Octa-BDE formulation has been higher in Iraq than in some other regions.Reassuringly,our estimates of exposure to our target BFRs via dust ingestion for the Iraqi population fall well below the relevant health-based limit values. | Layla Salih Al-Omran Stuart Harrad | 2016 | Emerging Contaminants2016，2，1： | 2 |
| 6 | Within-room and within-building temporal and spatial variations in concentrations of polybrominated diphenyl ethers (PBDEs) in indoor dust 显示文摘 | Muenhor D Harrad S | 2012 | Environment International2012，47，： | 1 |
| 7 | Polychlorinated biphenyls (PCBs) in the British environment : sinks, sources and temporal trends 显示文摘 | Harrad S J Sewart A P Alock R | 1994 | Environment Pollution1994，85，2： | 1 |
| 8 | Hexabromo- cyclododecanes in indoor dust from Canada, the United Kingdom, and the United States 显示文摘 | Abdallah M A E Harrad S Ibarra C | 2008 | Environ Sci Technol2008，42，2： | 1 |
| 9 | Analytical and environmental aspects of the flame retardant tetrabromobisphenol-A and its derivatives显示文摘 | Adrian Covaci Stefan Voorspoels Mohamed Abou-Elwafa Abdallah Tinne Geens Stuart Harrad Robin J. Law | 2008 | Journal of Chromatography A2008，，3： | 1 |
| 10 | Polychlorinatedbiphenyls (PCBs)in the British environment:Sinks,sources and temporal trends显示文摘 | Harrad S J Sewart A P Alcock R Boumphrey R Burnett V Davidson R D Halsall C Sanders G Waterhouse K | 1994 | Environmental Pollution1994，85，： | 1 |
| 11 | Concentrations of polybrominated diphenyl ethers in air and soil on a rural-urban transect across a major UK conurbation显示文摘 | HARRAD S HUNTER S | 2006 | Environmental Science and Technology2006，40，： | 1 |
| 12 | Poly(methylsilane)-a high ceramic yield precursor to silicon carbide显示文摘 | Harrad J A | 1991 | J Am Ceram Soc1991，74，3： | 1 |
| 13 | Comparison of polychlorinated biphenyl concentrations in indoor and outdoor air and the potential significance of inhalation as a human exposure pathway 显示文摘 | Currado G M Harrad S | 1998 | Environmental Science & Technology1998，32，20： | 1 |
| 14 | Levels and Trends of HBCD and BDEs in the European and Asian Environments,with Some Information for Other BFRs显示文摘 | Law R J Herzke D Harrad S | 2008 | Chemosphere2008，73，2： | 1 |
| 15 | Concentrations, sources and temporal trends in atmospheric polycyclic aromatic hydrocarbons in major conurbation 显示文摘 | Harrad S Laurie L | 2005 | Environ Monit2005，7，7： | 1 |
| 16 | Dehalogenation of polychlorinated biphenyls and polybrominated diphenyl ethers using a hybrid bioinorganic catalyst显示文摘 | HARRAD S ROBSON M HAZRATI S | 2007 | Journal of Environmen- tal Monitoring2007，9，： | 1 |
| 17 | Polychlorinated biphenyls (PCBs) in the British environment:Sinks, sources and temporal trends 显示文摘 | Harrad S J Sewart A P Alcock R | 1994 | Environmental Pollution1994，85，2： | 1 |
| 18 | Concentrations and sources of VOCs in urban domestic and public microenvironments显示文摘 | Kim Y M Harrad S Harrison R M | 2001 | Environmental Science and Technology2001，35，6： | 1 |
| 19 | Amblyopia treatment outcomes after screening before or at age 3 years:follow up from randomised trial显示文摘 | Williams C Northstone K Harrad RA | 2002 | BMJ2002，324，7353： | 1 |
| 20 | Amblyopia:contemporary clinical issues显示文摘 | Williams C Harrad R | 2006 | Strabismus2006，14，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员