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| 1 | Surveillance of Mycoplasma pneumoniae infection among children in Beijing from 2007 to 2012显示文摘 | Zhao Hanqing Li Shaoli Cao Ling Yuan Yi Xue Guanhua Feng Yanling Yan Chao Wang Liqiong Fan Zhaoyang Sun Hongmei | 2014 | Chinese Medical Journal2014，，7： | 61 |
| 2 | Deep Learning for Wireless Physical Layer: Opportunities and Challenges显示文摘Machine learning(ML) has been widely applied to the upper layers of wireless communication systems for various purposes, such as deployment of cognitive radio and communication network. However, its application to the physical layer is hampered by sophisticated channel environments and limited learning ability of conventional ML algorithms. Deep learning(DL) has been recently applied for many fields, such as computer vision and natural language processing, given its expressive capacity and convenient optimization capability. The potential application of DL to the physical layer has also been increasingly recognized because of the new features for future communications, such as complex scenarios with unknown channel models, high speed and accurate processing requirements; these features challenge conventional communication theories. This paper presents a comprehensive overview of the emerging studies on DL-based physical layer processing, including leveraging DL to redesign a module of the conventional communication system(for modulation recognition, channel decoding, and detection) and replace the communication system with a radically new architecture based on an autoencoder. These DL-based methods show promising performance improvements but have certain limitations, such as lack of solid analytical tools and use of architectures that are specifically designed for communication and implementation research, thereby motivating future research in this field. | Tianqi Wang Chao-Kai Wen Hanqing Wang Feifei Gao Tao Jiang Shi Jin | 2017 | China Communications2017，14，11： | 51 |
| 3 | JMJD3 is a histone H3K27 demethylase显示文摘组蛋白甲基化是参予细胞的过程的一个多样的数组的重要 epigenetic 现象并且被发现了与癌症被联系。几的 Recentidentification 嘘一 demethylases 证明了那嘘一甲基化是一个可逆过程。通过一条候选人途径,我们化学上有简历作为 H3K27demethylase 识别了 JMJD3。进 HeLa 房间的 JMJD3 的 Transfection 引起了整齐的乙醇 H3K27 的特定的减小,但是没在 di- 和单音的甲基 H3K27 上有效果,或嘘 H3K4 和 H3K9 上的一离氨酸 methylations。Theenzymatic 活动要求 JmjC 域和被建议了为余因子绑定重要的保存组氨酸。试管内生物化学的实验证明那 JMJD3directly 催化 demethylation。另外,我们发现 JMJD3 起来在前列腺癌症,和它的表示调整了在变形前列腺癌症是更高的。因此,我们作为能够把整齐的乙醇组从移开的 ademethylase 识别了 JMJD3 嘘一 H3 离氨酸 27 并且起来在前列腺癌症调整了。 | Yang Xiang Ziqi Zhu Gang Han Hanqing Lin Longyong Xu Charlie Degui Chen | 2007 | Cell Research2007，17，10： | 37 |
| 4 | Size distributions of aerosol and water-soluble ions in Nanjing during a crop residual burning event显示文摘To investigate the impact on urban air pollution by crop residual burning outside Nanjing,aerosol concentration,pollution gas concentration,mass concentration,and water-soluble ion size distribution were observed during one event of November 4-9,2010.Results show that the size distribution of aerosol concentration is bimodal on pollution days and normal days,with peak values at 60-70 and 200-300 nm,respectively.Aerosol concentration is 10 4 cm 3 ·nm 1 on pollution days.The peak value of spectrum distribution of aerosol concentration on pollution days is 1.5-3.3 times higher than that on a normal day.Crop residual burning has a great impact on the concentration of fine particles.Diurnal variation of aerosol concentration is trimodal on pollution days and normal days,with peak values at 03:00,09:00 and 19:00 local standard time.The first peak is impacted by meteorological elements,while the second and third peaks are due to human activities,such as rush hour traffic.Crop residual burning has the greatest impact on SO 2 concentration,followed by NO 2,O 3 is hardly affected.The impact of crop residual burning on fine particles(< 2.1 μm) is larger than on coarse particles(> 2.1 μm),thus ion concentration in fine particles is higher than that in coarse particles.Crop residual burning leads to similar increase in all ion components,thus it has a small impact on the water-soluble ions order.Crop residual burning has a strong impact on the size distribution of K +,Cl,Na +,and F and has a weak impact on the size distributions of NH 4 +,Ca 2+,NO 3 and SO 4 2. | Honglei Wang Bin Zhu Lijuan Shen Hanqing Kang | 2012 | Journal of Environmental Sciences2012，24，8： | 15 |
| 5 | Form-fnding methods for deployable mesh reflector antennas显示文摘Deployable high-frequency mesh reflector antennas for future communications and observations are required to obtain high gain and high directivity.In order to support these new missions,reflectors with high surface accuracy are widely required.The form-fnding analysis of deployable mesh reflector antennas becomes more vital which aims to determine the initial surface profle formed by the equilibrium prestress distribution in cables to satisfy the surface accuracy requirement.In this paper,two form-fnding methods for mesh reflector antennas,both of which include two steps,are proposed.The frst step is to investigate the prestress design only for the cable net structure as the circumferential nodes connected to the supporting truss are assumed fxed.The second step is to optimize the prestress distribution of the boundary cables connected directly to the supporting truss considering the elastic deformation of the antenna structure.Some numerical examples are carried out and the simulation results demonstrate the proposed form-fnding methods can warrant the deformed antenna reflector surface matches the one by design and the cable tension forces fall in a specifed range. | Li Tuanjie Jiang Jie Deng Hanqing Lin Zhanchao Wang Zuowei | 2013 | Chinese Journal of Aeronautics2013，26，5： | 15 |
| 6 | Glance Nets – efficient convolutional neural networks with adaptive hard example mining显示文摘Dear editor,Deep convolutional neural networks (CNNs) have become the dominant approach in various computer vision tasks such as image classification [1–4]. Despite the success of CNNs, it is impeded to deploy such deep CNN models in real-time tasks due to high computational complexity. To address the problem, we propose Glance Nets with several bypasses (Figure 1). In modern CNNs, it is believed that shallow layers provide lower-level features, whereas deep layers correspond to higherlevel features. However, it is not always | Hanqing SUN Yanwei PANG | 2018 | Science China(Information Sciences)2018，61，10： | 11 |
| 7 | Microbial aerosol characteristics in highly polluted and nearpristine environments featuring different climatic conditions显示文摘There is an increasing interest in understanding ambient bioaerosols due to their roles both in health and in climate. Here, we deployed an Ultraviolet Aerodynamic Particle Sizer to monitor viable(fluorescent) bioaerosol concentration levels at city centers(highly polluted) and their corresponding suburbs(near pristine)(total 40 locations) in 11 provinces featuring different climate zones in China between July 16 and 28, 2013. The concentration levels of viable bioaerosol particles(Bio PM) of [0.5 lm were measured, and corresponding percentages of Bio PM%(biological fraction of total PM) and Bio PM2.5%(biological fraction of PM2.5) in particulate matter(PM)and Bio PM, respectively, were determined. For some key cities, indoor viable bioaerosol levels were also obtained.In addition, bacterial structures of the air samples collected across these monitoring locations were studied using pyrosequencing. Bio PM concentration levels ranged from2.1 9 104 to 2.4 9 105/m3 for city centers [Bio PM% =6.4 %(±6.3 %)] and 0.5 9 104 to 4.7 9 105/m3 for suburbs [Bio PM% = 10 %(±8.7 %)]. Distinctive bioaerosol size distribution patterns were observed for different climate zones, e.g., some had fluorescence peaks at 3 lm, while the majority had peaks at 1 lm. Ambient bacterial aerosol community structures were also found different for different geophysical locations. Results suggest that there was a poor overall relationship between PM and Bio PM across 40 monitoring locations(R2= 0.081, two-tailed P value =0.07435). Generally, city centers had higher PM concentrations than suburbs, but not Bio PM and Bio PM%. Indoor bioaerosol levels were found at least tenfold higher than those corresponding outdoors. Bacillus was observed to dominate the bacterial aerosol community in the air sample. | Kai Wei Yunhao Zheng Jing Li Fangxia Shen Zhuanglei Zou Hanqing Fan Xinyue Li Chang-yu Wu Maosheng Yao | 2015 | Science Bulletin2015，60，16： | 10 |
| 8 | A NON-PARAMETER BAYESIAN CLASSIFIER FOR FACE RECOGNITION显示文摘A non-parameter Bayesian classifier based on Kernel Density Estimation (KDE)is presented for face recognition, which can be regarded as a weighted Nearest Neighbor (NN)classifier in formation. The class conditional density is estimated by KDE and the bandwidthof the kernel function is estimated by Expectation Maximum (EM) algorithm. Two subspaceanalysis methods-linear Principal Component Analysis (PCA) and Kernel-based PCA (KPCA)are respectively used to extract features, and the proposed method is compared with ProbabilisticReasoning Models (PRM), Nearest Center (NC) and NN classifiers which are widely used in facerecognition systems. The experiments are performed on two benchmarks and the experimentalresults show that the KDE outperforms PRM, NC and NN classifiers. | Liu Qingshan Lu Hanqing Ma Songde (Nat. Lab of Pattern Recognition, Inst. of Automation, Chinese Academy of Sciences, Beijing 100080) | 2003 | Journal of Electronics(China)2003，20，5： | 9 |
| 9 | Quantitative determination of AI-2 quorum-sensing signal of bacteria using high performance liquid chromatography–tandem mass spectrometry显示文摘Autoinducer 2(AI-2), an important bioactive by-product of the Lux S-catalyzed S-ribosylhomocysteine cleavage reaction in the activated-methyl-cycle, has been suggested to serve as a universal intra- and inter-species signaling molecule. The development of reliable and sensitive methods for quantitative determination of AI-2 is highly desired.However, the chemical properties of AI-2 cause difficulty in its quantitative analysis.Herein, we report a high performance liquid chromatography-tandem mass spectrometric method that enables reproducible and sensitive measurement of AI-2 concentrations in complex matrixes. 4,5-Dimethylbenzene-1,2-diamine(DMBDM), an easy-to-obtain commercial reagent, was used for the derivatization treatment. The assay was linear in the concentration range of 1.0–1000 ng/m L(R^2= 0.999) and had a lower limit of quantification of0.58 ng/m L. The method exhibited several advantages, e.g., high selectivity, wide linear response range, and good sensitivity. Furthermore, the effectiveness of the method was further validated through measuring AI-2 concentrations in the cell-free culture supernatant from Escherichia coli wild type. | Fang Xu Xiangning Song Peijie Cai Guoping Sheng Hanqing Yu | 2017 | Journal of Environmental Sciences2017，29，2： | 8 |
| 10 | Expression and signal regulation of the alternative oxidase genes under abiotic stresses显示文摘在他们的自然环境的植物经常面对各种各样的不能生活的压力,例如干旱,高咸度,并且寒心。植物线粒体包含其他的 oxidase (AOX ) ,它被原子基因的一个小家庭编码。AOX 基因被显示了对不能生活的压力高度应答。用有改变 AOX 表示的层次的转基因的植物, AOX 基因为不能生活的应力公差是重要的,这被证实了。尽管在不能生活的压力下面的 AOX 的角色广泛地被学习了,这个话题上有几优秀评论, AOX 基因家庭成员和在不能生活的压力下面的 AOX 基因的信号规定的微分表情模式广泛地没被总结。这里,我们考察并且讨论这二个重要问题的当前的进步。 | Hanqing Feng Dongdong Guan Kun Sun Yifeng Wang Tengguo Zhang Rongfang Wang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 7 |
| 11 | Field Modeling Method for Identifying Urban Sphere of Influence:A Case Study on Central China显示文摘With rapid development of urbanization and regional interaction and interdependence,regional urban agglomeration planning becomes more and more important in China,in order to promote integrated development of various cities with close interrelationship.However,it is still arguable academically on how to define the boundary or which cities to be included for the urban agglomeration of a region.This paper aims to shed lights on how to identify urban spheres of influence scientifically by introducing field modeling method and by practicing a case study on 168 cities in Central China.In our field modeling method,the influence intensities of cities were measured by a comprehensive index and urban spheres of influence were represented spatially by field intensity.Then,their classification and spatial distribution characteristics of study area in 2007 were identified and explored by using GIS and statistical methods.The result showed that:1) Wuhan is the absolute dominant city in Central China;2) the provincial capital cities dominate their own provinces and there are no other lower grade agglomeration centers;and 3) the basic types of organization form of urban sphere of influence are single-polar type,agglomeration type,close-related group type and loose-related group type. | DENG Yu LIU Shenghe WANG Li MA Hanqing WANG Jianghao | 2010 | Chinese Geographical Science2010，20，4： | 7 |
| 12 | Isolation,structural determination and cytotoxic activity of two new ceramides from the root of Isatis indigotica显示文摘Two new ceramides were isolated from the 95% EtOH extract of traditional Chinese medicinal plant Isatis indigotica. Their structures were elucidated as 1-O-β-D-glucopyranosyl-(2S, 3R)-N-(2'-hydroxypentacosanoyl)-octadeca-11E-sphingenine (1) and 1-O-β-D-glucopyranosyl-(2S,3R)-N-(2'-hydroxyhe xacosanoyl)-octadeca-11E-sphingenine (2) on the basis of spectroscopic data. Their cytotoxic effects were evaluated by using MTT method. | SUN DongDong DONG WeiWei LI Xiang ZHANG HanQing | 2009 | Science China Chemistry2009，52，5： | 7 |
| 13 | Current-limiting characteristics of saturated iron-core fault current limiters in VSC-HVDC systems based on electromagnetic energy conversion mechanism显示文摘A common method to examine the current-limiting performance of saturated iron-core fault current limiter(SI-FCL) in high-voltage direct-current transmission based on voltage source converter(VSC-HVDC) systems is to solve differential equations based on the system fault transient characteristics and the equivalent inductance calculation equation. This method analyzes the fault current of the VSC-HVDC system in the time domain. However, it is computationally complex and cannot directly reflect the relationship between parameters and the currentlimiting effect of the SI-FCL.In this paper,the relationship between the magnetic flux density and magnetic field energy of the SI-FCL is analyzed. The energy exchange between the DC capacitor and the SI-FCL in the DC short circuit fault process is analyzed. From the perspective of electromagnetic energy conversion, the criterion for determining the current-limiting ability of the SI-FCL in the transient process is given based on the parameters of the SI-FCL and VSC-HVDC system. On this basis, the characteristics of the DC side fault current and the capacitor voltage when the SI-FCL has current-limiting ability are examined.Based on the parameters of the SI-FCL and VSC-HVDC system, a method for calculating the fault current peak value and capacitor voltage drop time is given. Finally, the accuracy of the analysis of the SI-FCL in the VSC-HVDC system based on the electromagnetic energy conversion mechanism is demonstrated through a case study and simulation results of the VSC-HVDC system with different SI-FCLs. | Botong LI Hanqing CUI Fangjie JING Bin LI Yichao LIU | 2019 | Journal of Modern Power Systems and Clean Energy2019，7，2： | 7 |
| 14 | NUMERICAL STUDIES ON RESONANT AND ENHANCEMENT EFFECTS FOR COUPLING OF MICROWAVE PULSES INTO NARROW SLOTS显示文摘In this paper, modifications to the finite-difference time-domain(FD-TD) method for modeling microwave pulse coupling into a slot, which is much narrower than one conventional FD-TD cell, are discussed. The coupling process of microwave pulse into a slot is studied by using the modified FD-TD method, and the dependence of microwave coupling on slot sizes, the carrier frequencies and the polarization directions of the incident waves is analysed. Resonant and enhancement effects which occur in this process are observed. The condition at which the resonant effect takes place is also presented. | Wang Jianguo Yu Hanqing Liu Guozhi Chen Yusheng Fan Ruyu (Northwest Institute of Nuclear Technology, Branch 15, P. O. Box 69, Xi’an 710024)Ge Debiao(Department of Physics, Xidian University, Xi’an 710071) | 1998 | Journal of Electronics(China)1998，15，2： | 6 |
| 15 | RATE DEPENDENT STRESS-STRETCH RELATION OF DIELECTRIC ELASTOMERS SUBJECTED TO PURE SHEAR LIKE LOADING AND ELECTRIC FIELD显示文摘The performance of dielectric elastomer(DE) transducers is significantly affected by viscoelastic relaxation-induced electromechanical dissipations.This paper presents an experimental study to obtain the rate dependent stress-stretch relation of DE membranes(VHB TM 9473) subjected to pure shear like loading and electric loading simultaneously.Stretching rate dependent behavior is observed.The results also show that the tensile force decreases as the voltage increases.The observations are compared with predictions by a viscoelastic model of DE.This experiment may be used for further studies of dynamic electromechanical coupling properties of DEs. | Shaoxing Qu Ke Li Tiefeng Li Hanqing Jiang Miao Wang Zhenhua Li | 2012 | Acta Mechanica Solida Sinica2012，25，5： | 5 |
| 16 | Development and characterization of a clinical strain of Coxsackievirus A16 and an eGFP infectious clone显示文摘Coxsackievirus A16(CA16) is one of the major causes of hand, foot, and mouth disease(HFMD) worldwide, which is a common illness that affects children. The frequent occurrence of HFMD outbreaks has become a serious public health problem in Asia. Therefore, it is important to understand the pathogenesis and replication of CA16. In this study, a stable infectious c DNA clone of an epidemic strain of Coxsackievirus A16(CA16) was assembled, and subsequently a reporter virus(e GFP-CA16) was constructed by inserting the e GFP gene between the 5'-UTR and the N-terminus of VP4, with the addition of a 2A protease cleavage site(ITTLG) at its C-terminus. This was transfected into Vero cells to generate infectious recombinant viruses. The growth characteristics and plaque morphology, in vitro, in mammalian cells were found to be indistinguishable between the parental and recombinant viruses. Although the e GFP-CA16 showed smaller plaque size as compared to recombinant CA16, both were found to exhibit similar growth trends and EC50 of NITD008. In summary, this stable infectious c DNA clone should provide a valuable experimental system to study CA16 infection and host response. The e GFP-CA16 is expected to provide a powerful tool to monitor e GFP expression in infected cells and to evaluate the antiviral activity of potential antiviral agents in the treatment of CA16 infections. | Chenglin Deng Xiaodan Li Siqing Liu Linlin Xu Hanqing Ye Cheng-Feng Qin Bo Zhang | 2015 | Virologica Sinica2015，30，4： | 5 |
| 17 | Corrosion behavior of Mg-Zn-Ca amorphous alloys with Nd addition in simulated body fluids显示文摘The effects of Nd addition on corrosion behavior of Mg66Zn30Ca4 amorphous alloys in simulated body f luids(SBF) were studied in this paper. Electrochemical properties of the samples before and after corrosion were determined. Surface morphologies of samples after immersion in SBF at 37℃ for different times were observed under scanning electron microscope(SEM). Results show that the corrosion resistance of Mg-based alloys in SBF is improved with the addition of Nd element. The electrochemical properties indicate that microalloying Nd element to the alloys leads to an ennoblement in the open circuit potentials of the alloys and a decrease in the anodic current density in SBF, especially for the Mg66-xZn30Ca4 Ndx alloys with Nd content of 1.0at.%-1.5at.%. It was observed that the surface morphologies of the alloys immersed in SBF change with the Nd addition. A f lakelike structure parallel to the alloy substrate formed on the surface of 1.0at.% Nd-containing alloy immersed in SBF for 7 days improves the corrosion resistance of the amorphous alloys by blocking the corrosion liquid from attacking the alloys. | Qin Chunling Xiao Tongna Li Yongyan Wang Zhifeng Liu Li Xiong Hanqing Zhao Weimin | 2014 | China Foundry2014，11，6： | 5 |
| 18 | Effect of combined medicated thread moxibustion plus needle picking therapy of Zhuang nationality medicine on antioxidant levels in a rat model of sciatica显示文摘OBJECTIVE: To investigate the effect and underlying mechanisms of combined medicated thread moxibustion therapy plus needle picking therapy of Zhuang nationality medicine on antioxidant levels in a rat model of sciatica.METHODS: One hundred Wistar rats, of specific pathogen free level, were randomly divided into five groups: normal control group, model group,medicated thread moxibustion group, needle picking group, and combination group. Each group contained 20 rats. In the model, medicated thread moxibustion, needle picking, and combination groups,sciatica models were established through chronicconstriction injury of the sciatic nerve. After the model was established, the rats in the medicated thread moxibustion, needle picking, and combination groups were given the corresponding therapies for 21 days. The control and model groups received no treatment. Reactive oxygen species, superoxide dismutase, malondialdehyde, and total antioxidant capacity changes were determined.Nicotinamide adenine dinucleotide phosphate(NADPH) oxidase subunit NADPH oxidases 4(NOX4) m RNA expression and the morphology of cells were observed to detect apoptosis of gamma-aminobutyric acid ergic(GABAergic) neurons.RESULTS: Compared with control group, reactive oxygen species and malondialdehyde levels rose significantly in the model group(P < 0.01), while superoxide dismutase and total antioxidant capacity levels were lowered(P < 0.05). Compared with the model group, reactive oxygen species and malondialdehyde decreased in the needle picking group(P < 0.05), while superoxide dismutase levels were increased(P < 0.05); reactive oxygen species and malondialdehyde significantly decreased in the combination group(P < 0.01). In addition, the model group had higher NOX4 m RNA expression than that of the control group(P < 0.05), and the combination group had lower expression levels than that of the model group(P < 0.05). Apoptosis of GABAergic neurons was observed in the model group, and was attenuated after combined therapy.CONCLUSION: The medicated thread moxibustion therapy plus needle picking therapy of Zhuang nationality medicine can prevent oxidative damage in the rat model of sciatica via down-regulating NOX4 expression, improving antioxidant capacity, and in-hibiting the oxidative damage pathway of GABAergic neurons. | Tang Hanqing Zheng Jianyu Li Tianzi Li Keming Li Xiaohua Dou Xibin Huang Chunchuan Liang Ye | 2016 | Journal of Traditional Chinese Medicine2016，36，6： | 4 |
| 19 | Trans Complementation of Replication-defective Omsk Hemorrhagic Fever Virus for Antiviral Study显示文摘Omsk hemorrhagic fever virus(OHFV) is a tick-borne flavivirus classified as a biosafety level-4(BSL4) pathogen. Studies of OHFV are restricted to be conducted within BSL4 laboratories. Currently, no commercial vaccines or antiviral drugs are available against OHFV infection. In this study, we recovered a replication-deficient OHFV with an NS1 deletion(OHFVDNS1) and reporter virus replacing NS1 with the Gaussia luciferase(Gluc)(OHFV-ΔNS1-Gluc). Both the defective OHFVDNS1 and OHFV-ΔNS1-Gluc virus could only replicate efficiently in the BHK21 cell line expressing NS1(BHK21NS1) but not in na?ve BHK21 cells. The Gluc reporter gene of OHFV-ΔNS1-Gluc virus was maintained stably after serial passaging of BHK21NS1 cells and was used to surrogate the replication of OHFV. Using NITD008, OHFV-ΔNS1-Gluc virus was validated for antiviral screening, and high-throughput screening parameters were optimized in a 96-well plate format with a calculated Z0 value above 0.5. The OHFV-ΔNS1-Gluc reporter virus is a powerful tool for antiviral screening as well as viral replication and pathogenesis studies in BSL2 laboratories. | Qiuyan Zhang Na Li Chenglin Deng Zherui Zhang Xiaodan Li Kentaro Yoshii Hanqing Ye Bo Zhang | 2019 | Virologica Sinica2019，34，4： | 4 |
| 20 | Experimental study on freezing of liquids under static magnetic field显示文摘Freezing processes of several liquids under static magnetic field(SMF) less than 50 mT were investigated. Central temperature of liquid samples held in glass test tubes immersed in a liquid bath was measured and collected. Nucleation temperature and phase transition time were obtained from freezing curves. Normality tests were performed for nucleation temperature of these liquids with/without magnetic field and normality distributions were justified. Analysis of variances was carried out for nucleation temperature of these liquids with magnetic field flux density as the influencing factor. Results showed that no significant difference was found for deionized water with or without SMF. However, differences exist in 0.9% NaCl solution and 5% ethylene glycol solution with and without SMF. Nucleation temperature of 0.9% NaCl with SMF is lower than that without SMF, while its phase transition time is shorter than that without SMF. Nucleation temperature of 5% ethylene glycol with SMF is higher than that without SMF, while its phase transition time is not modified with SMF. | Hongxia Zhao Feng Zhang Hanqing Hu Sheng Liu Jitian Han | 2017 | Chinese Journal of Chemical Engineering2017，25，9： | 4 |
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