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199篇 您的检索式:作者名="Hamilton M W"
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1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2Bending strength of steel beams with corrugated webs显示文摘Elgaaly M Seshadri A Hamilton R W 1997Journal of Structural Engineering1997,123,6:1
3Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R 2009Journal of Bacteriology2009,191,16:1
4Excess of nonparental bands in offspring from known pedigrees assayed using RAPD PCR显示文摘Reidy M F Hamilton W J Aquadro C F 1992Nucleic Acids Res1992,20,:1
5Bending strength of steel beams with corrugated webs显示文摘Elgaaly M Seshadri A Hamilton R W 1997Journal of Structural Engineering1997,123,6:1
6Expected Appreciation in Urban Housing Markets 显示文摘Hamilton B W Schwab R M 1985Journal of Urban Economics1985,1,18:1
7Antibiotic Activity of Natural Product:Propolis显示文摘Brumfitt W Hamilton M J Franklin I 1990Microbios1990,62,:1
8Shear strength of beams with corrugated webs显示文摘Elgaaly M Hamilton R W Seshadri A 1996Journal of Structural Engineering1996,122,4:1
9Shear strength of beams with corrugated webs显示文摘Elgaaly M Hamilton R W Seshadri A 1996Journal of Structural Engineering1996,122,4:1
10Intrao- perative urinary output does not predict postoperative re- nal function in patients undergoing abdominal aortic re- vascularization显示文摘Alpert R A Roizen M F Hamilton W K 1984Surgey1984,95,6:1
11Bending strengths of beams with corrugated webs 显示文摘ELGAALY M SESHADRI A HAMILTON R W 1997Journal of Structur- al Engineering1997,123,6:1
12Characterization of the response of bone marrow-derived progenitor cells to cyclic strain: implications for vascular tissue-engineering applications 显示文摘HAMILTON D W MAUL T M VORP D A 2004Tissue Eng2004,10,34:1
13Utility of Ictal SPECT in the presurgical evaluation of Rasmussen's encephalitis显示文摘Bumeo JG Hamilton M Vezina W 2006Can J Neurol Sci2006,33,1:1
14Shear strength of beams with corrugated webs 显示文摘ELGAALY M HAMILTON R W SESHADRI A 1996Journal of Structural Engineering1996,122,4:1
15Bending Strength of Steel Beams with Corrugated Webs 显示文摘ELGAALY M SESHADRI A HAMILTON R W 1997Journal of Structural Engineering1997,123,6:1
16Elderly Psychiatric Patients and the Burden on the Household显示文摘Hoening J Hamilton M W 1966Psychiatr Neurol(Basel)1966,152,5:1
17The mechanical properties of 316L/304L stainless steels, Alloy 718 and Mod 9Cr-1Mo after irradiation in a spallation environment 显示文摘Maloy S A James M R Willcutt G Sommer W F Sokolov M Snead L L Hamilton M L Garner F 2001Journal of Nuclear Material2001,296,:1
18Bending strength of steel beams with corrugated webs显示文摘Elgaaly M Seshadri A Hamilton R W 1997Journal of Structural Engineering1997,123,6:1
19Bending strength of steel beams with corrugated webs显示文摘ELGAALY M SESHADRI A HAMILTON R W 1997J Struct Eng1997,123,6:1
20Destruction of aflatoxin in corn with sodium bisufite显示文摘Hagler J R W M Hutchins J E Hamilton P B 1982J Food Prot1982,45,:1
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