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115篇 您的检索式:作者名="Hamilton C W"
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1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2Evidence for a male-produced sex pheromone in the western flower thrips Frankliniella occidentals显示文摘Kirk W D J Hamilton J G C 0,,01:1
3Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R 2009Journal of Bacteriology2009,191,16:1
4Acousticand other physical properties of shallow-water sediments offSan Diego显示文摘HAMILTON E L MENARD H W SHIPEX C J 1956 1956The Journal of the Acoustical Society ofAmerica1956,28,:1
5Excess of nonparental bands in offspring from known pedigrees assayed using RAPD PCR显示文摘Reidy M F Hamilton W J Aquadro C F 1992Nucleic Acids Res1992,20,:1
6显示文摘Raich W J Hamilton C S 1957J Am Chem Soc1957,79,:1
7Free rotation of methyl groups in dimethyltin difluoride显示文摘RUSH J J HAMILTON W C 1966Inorg Chem1966,5,12:1
8Evidence for a maleproduced sex pheromone in the western flower thrips Frankliniella occidentalis显示文摘KIRK W J HAMILTON J G C 2004Journal of Chemical Ecology2004,30,1:1
9A neutron diffraction refinement of the crystal structure of dimethylglyoxime显示文摘Hamilton W C 1961Acta Crystallogr1961,14,:1
10Methoxyl groups of plant pectin as a precursor of atmospheric methane:Evidence from deuterium labelling studies显示文摘Keppler F Hamilton J T G McRoberts W C 0,,04:1
11Reliable Deepwater Structural Casing Installation Using Controlled Jetting显示文摘Beck R D Jackson C W Hamilton T K 1991SPE 225421991,,:1
12Predicting invasions of woody plants introduced into North America显示文摘REICHARD S H HAMILTON C W 1997Conservation Biology1997,11,1:1
13Oxidation of gamma-irradiated ultrahigh molecular weight polyethylene显示文摘Coote C F Hamilton J V McGimpsey W G 2000Journal of Applied Polymer Science2000,77,11:1
14Spontaneous improvement in late rectal mucosal changes after radiotherapy for prostate cancer显示文摘Peter C O’Brien Christopher S Hamilton James W Denham Ralph Gourlay C.Ian V Franklin 2004International Journal of Radiation Oncology, Biology, Physics2004,,1:1
15An electrically calibrated pyroelectric radiometer system显示文摘HAMILTON C A DAY G W PHELAN R J 1976NBS TN1976,,:1
16Design recommendations for concrete structures prestressed with FRP tendons显示文摘DOLAN C W HAMILTON H R 2001Ksce Journal of Civil Engineering2001,18,2:1
17Grain refinement in 7075 aluminum by thermo-mechanical processing显示文摘John A W Paton N E Hamilton C H 1981Metallurgical Transactions A1981,12,7:1
18Modu- lation of the humoral immune response of swine and mice mediated by toxigenic Pasteurella rnultocida 显示文摘Jordan R W Hamilton T D Hayes C M 2003FEMS Immunol Med Microbiol2003,39,1:1
19Phosphorus cycling in the Rocky Mountains of Colorado显示文摘Lewis W M Grant M C Hamilton S K 1985Oikos1985,45,:1
20HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies:This document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA)显示文摘Ackerman MJ Priori SG Willems S Berul C Brugada R Calkins H Camm AJ Ellinor PT Gollob M Hamilton R Hershberger RE Judge DP Le Marec H McKenna W J Schulze-Bahr E Semsarian C Towbin JA Watkins H Wilde A Wolpert C Zipes DP 2011Europace2011,13,8:1
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