| 1 | Effect of point application on chronic obstructive pulmonary disease in stationary phase and effects on pulmonary function:A systematic evaluation of randomized controlled trials显示文摘OBJECTIVE:To evaluate clinical efficacy of point application or adjuvant therapy on chronic obstructive pulmonary disease in stationary phase and effects on pulmonary functions.METHODS:Computer retrieved CNKI,VIP,CBM and other databanks and manual operations retrieved correlative literatures to find randomized controlled trials(RCTs) about comparison between point application or adjuvant therapy and no-point-applications for treatment of chronic obstructive pulmonary disease in stationary phase in China.RevMan 5.0 software was used for Meta analysis.RESULTS:Among 3481 cases in the inclusive 32 RCTS,1780 cases were in the test group and 1701 cases in the control group.Meta analysis indicated:1) clinical efficacy:the groups containing point application therapy all were better than the groups of no-point-application;2) force vital capacity(FVC):There was no statistically significant difference between the group of point application plus Western Medicine and the Western Medicine group;3) force expiratory volume 1(FEV1):The groups containing point application therapy were better than the no-point-application;4) FEV1%:the groups of point application plus Western Medicine were better than the Western Medicine groups;5) FEV1/FVC:there was a significant difference between the group of point application plus Chinese drugs and the group of Chinese drug.CONCLUSION:Point application can increase clinical efficacy of chronic obstructive pulmonary disease in stationary phase in varying degrees,and different combinations of point application with Chinese drugs or Western Medicines have incomplete same actions in improvement of pulmonary function and therapeutic effect. | Fengsen Li Zhen Gao Jing Jing Dan Xu Halmurat.Upur | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 12 |
| 2 | Effect of Jianpi therapy in treatment of chronic obstructive pulmonary disease:a systematic review显示文摘OBJECTIVE:To evaluate the efficacy of Jianpi therapy in Traditional Chinese Medicine (TCM) for treatment of chronic obstructive pulmonary disease (COPD) in stable phase by performing a systematic review and meta-analysis. METHODS: The literatures concerning randomized controlled trials (RCTs) and quasi-RCTs comparing TCM treatment plus Western Medicine (WM) treatment with TCM alone, orTCM treatment vs no treatment, placebo for stable phase of COPD were searched in PubMed (1990-December 2010), in English and using Chinese National Knowledge Infrastructure (CNKI, 1990-December 2010), Chinese Biomedical Database (1990-December 2010), Wangfang Database (1990-December 2010), and Weipu (VIP) Database in Chinese. The quality assessment and data extraction for RCTs were conducted by two reviewers independently. Jadad scale and allocation concealment were used to assess the quality of the included studies, and meta-analyses were conducted with the Collaboration's Revman 5.0 software. RESULTS: Seventeen RCTs or quasi-RCTs involving 1269 patients were included. The methodological quality was poor in all trials except one trial (Jadad score=4). In the meta-analysis, TCM-WM treatment was significantly superior to WM treatment in cure rate [OR=3.82, 95%CI (2.45, 5.95)], and the effective rate between TCM treatment and placebo also had significant difference [OR=4.31, 95%CI (2.35, 7.91)]. Moreover, pulmonary function of the patients in TCM-WM group and TCM group was significantly improved [forced vital capacity (FVC), P=0.01, quality of life, P<0.001]. CONCLUSION: The experience in TCM-WM treatment of COPD in stable phase was encouraging. The current evidence shows that TCM-WM treatment might be more efficient in effective rate, quaity of life, and FVC than WM treatment alone. But for forced expiratory volume in one second (FEV1) and FEV1/FVC, no matter TCM-WM treatment compared with WM treatment alone or TCM treatment compared with placebo, there was no significant difference, with no obvious adverse reactions. Due to the low methodological quality of trials included, more RCTs of high quality in large scale are required. | Zhen Gao Yingying Liu Juhong Zhang Halmurat.Upur | 2013 | Journal of Traditional Chinese Medicine2013，33，1： | 3 |
| 3 | Hypercoagulability in cancer patients grouped by syndromes differentiated with the theory of abnormal hilit in traditional Uyghur medicine显示文摘OBJECTIVE:To investigate the relationship in malignant-neoplasm patients of hypercoagulability between syndromes differentiated with the theory of abnormal hilit in traditional Uyghur medicine(TUM).METHODS:A total of 248 patients with malignant tumors were enrolled.Based on the theory of TUM they were divided into two groups:abnormal Savda and abnormal Non-Savda(including abnormal Khan,abnormal Sepra and abnormal Belghem types);fifty healthy volunteers were selected as controls.Platelet(PLT),prothrombin time(PT),plasma fibrinogen(FIB),thrombin time(TT),activated partial thromboplastin time(aPTT)and D-Dimer(D-D)were measured in both groups.RESULTS:Compared with the control and abnor-mal Non-Savda groups,in the abnormal Savda group the PLT count increased(P<0.05),the PT was lengthened(P<0.01),and the FIB significantly increased(P<0.01).D-Ds in the three groups were significantly different(P<0.05).No significant difference was found inTT and aPTT values(P>0.05).CONCLUSION:Hypercoagulability existed in patients with malignant tumors in the different types of TUM syndromes,especially in the abnormal Savda group;this was characterized by increased blood viscosity,platelet aggregation and thrombosis.D-D appears to be a significant predictor for the therapeutic effect of TUM in relation to malignant tumor therapies. | Yin Chen Halmurat.Upur Meizuo Zhong Renaguli.Aizezi | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 0 |
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