|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of hepatorenal syndrome显示文摘Hepatorenal syndrome(HRS) is defined as development of renal dysfunction in patients with chronic liver diseases due to decreased effective arterial blood volume. It is the most severe complication of cirrhosis because of its very poor prognosis. In spite of several hypotheses and research, the pathogenesis of HRS is still poorly understood. The onset of HRS is a progressive process rather than a suddenly arising phenomenon. Since there are no specific tests for HRS diagnosis, it is diagnosed by the exclusion of other causes of acute kidney injury in cirrhotic patients. There are two types of HRS with different characteristics and prognostics. Type 1 HRS is characterized by a sudden onset acute renal failure and a rapid deterioration of other organ functions. It may develop spontaneously or be due to some precipitating factors. Type 2 HRS is characterized by slow and progressive worsening of renal functions due to cirrhosis and portal hypertension and it is accompanied by refractory ascites. The only definitive treatment for both Type 1 and Type 2 HRS is liver transplantation. The most suitable bridge treatment or treatment for patients who are not eligible for transplantation is a combination of terlipressin and albumin. For the same purpose, it is possible to try hemodialysis or renal replacement therapies in the form of continuous veno-venous hemofiltration. Artificial hepatic support systems are important for patients who do not respond to medical treatment. Transjugular intrahepatic portosystemic shunt may be considered as a treatment modality for unresponsive patients to medical treatment. The main goal of clinical surveillance in a cirrhotic patient is prevention of HRS before it develops. The aim of this article is to provide an updated review about the physiopathology of HRS and its treatment. | Halit Ziya Dundar Tuncay Yilmazlar | 2015 | World Journal of Nephrology2015，4，2： | 15 |
| 2 | Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats显示文摘AIM: To evaluate the role of reactive oxygen species in the pathogenesis of acute ethanol-induced gastric mucosal lesions and the effect of Nigella sativa L oil (NS) and its constituent thymoquinone (TQ) in an experimental model.METHODS: Male Wistar albino rats were assigned into 4groups. Control group was given physiologic saline orally (10 mL/kg body weight) as the vehicle (gavage); ethanol group was administrated 1 mL (per rat) absolute alcohol by gavage; the third and fourth groups were given NS (10 mL/kg body weight) and TQ (10 mg/kg body weight p.o) respectively 1 h prior to alcohol intake. One hour after ethanol administration, stomach tissues were excised for macroscopic examination and biochemical analysis.RESULTS: NS and TQ could protect gastric mucosa against the injurious effect of absolute alcohol and promote ulcer healing as evidenced from the ulcer index (UI) values. NS prevented alcohol-induced increase in thiobarbituric acid-reactive substances (TBARS), an index of lipid peroxidation. NS also increased gastric glutathione content (GSH), enzymatic activities of gastric superoxide dismutase (SOD) and glutathione-S-transferase (GST). Likewise, TQ protected against the ulcerating effect of alcohol and mitigated most of the biochemical adverse effects induced by alcohol in gastric mucosa, but to a lesser extent than NS. Neither NS nor TQ affected catalase activity in gastric tissue.CONCLUSION: Both NS and TQ, particularly NS can partly protect gastric mucosa from acute alcohol-induced mucosal injury, and these gastroprotective effects might be induced, at least partly by their radical scavenging activity. | Mehmet Kanter Halit Demir Cengiz Karakaya Hanefi Ozbek | 2005 | World Journal of Gastroenterology2005，11，42： | 9 |
| 3 | 响应面法优化电炉炼钢粉尘中Zn的选择性浸出显示文摘研究浸出参数对电炉炼钢粉尘灰中选择浸出性Zn的影响,以Zn和Fe的浸出率为响应变量,以硫酸浓度、浸出温度、浸出时间和液固比为独立变量,采用基于三水平Box-Behnken的响应面法对浸出参数进行优化。对试验结果进行ANOVA分析和验证。在硫酸浓度为2.35 mol/L,浸出温度为25℃,浸出时间为56.42 min,液固比为5的条件下,可得到Zn的最大浸出率为79.09%,Fe的最小浸出率为4.08%。通过ANOVA分析表明,对Zn和Fe浸出率影响最大的因素为硫酸浓度和浸出温度。基于响应面法的模型与试验数据具有很好的一致性,Zn和Fe浸出率的相关系数分别为0.98和0.97。 | Mehmet KUL Kürsad Oguz OSKAY Mehmet SIMSIR Halit SüBüTAY Habip KIRGEZEN | 2015 | Transactions of Nonferrous Metals Society of China2015，25，8： | 5 |
| 4 | Outcome of repeated micro-surgical testicular sperm extraction in patients with non-obstructive azoospermia显示文摘瞄准:为了评估重复微外科的阴囊的精子抽取(mTESE ) 的结果,在非妨碍的精子缺乏(NOA ) 尝试格,在与病人的起始的阴囊的组织学结果的关系。方法:有 mTESE 在精子注射(ICSI ) 尝试的以前的 intracytoplasmic 在被执行了的 NOA 的 68 个病人的一个总数被考察。结果:在有 NOA 的 68 个病人之中,第一 mTESE 产出成熟精子为在 44 的 ICSI (64%)(Sp^+) ,并且在留下失败了 24 (36%)(Sp^-) 。跟随他们的第一试用, 24 个病人决定经历第二 mTESE。这 24 个病人,没有精子在 5 个病人被获得,并且 Sp^+ 而是没有授精 / 怀孕在 19 被完成。在这 24 格中, mTESE 连续地为二被重复(n = 24 ) ,三(n = 4 ) 并且四(n = 1 ) 时间。第二次尝试从 Sp^+ 组从 Sp^+ 组和 16/19 病人在 3/5 病人产出成熟精子。在第三和第四试用,原来的 Sp^+ 病人的 4/4 和 1/1 分别地又是 Sp^+ 。主要阴囊的组织学的分发包括了 Sertoli 房间唯一的症候群(16%) ,成熟拘捕(22%) ,低亚硫酸钠精子发生(21%) 和焦点的精子发生(41%) 。总的来说在重复 mTESE,尝试的 24/29 (82%) 是最后 Sp^+ 。结论:在有 NOA 的病人的重复 mTESE 是一种可行选择,产出更加高的精子恢复率。在有 NOA 的病人, mTESE 可以安全地被重复至少一次增加精子检索率,以及增加检索新鲜精子启用 ICSI 的机会。 | Halit Talas Onder Yaman Kaan Aydos | 2007 | Asian Journal of Andrology2007，9，5： | 4 |
| 5 | Prediction of Coronary Heart Disease Using Risk Factor Categories显示文摘 | Peter W.F. Wilson Ralph B. D’Agostino Daniel Levy Albert M. Belanger Halit Silbershatz William B. Kannel | 1998 | Circulation1998，，18： | 3 |
| 6 | Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study显示文摘 | Emelia J. Benjamin Philip A. Wolf Ralph B. D’Agostino Halit Silbershatz William B. Kannel Daniel Levy | 1998 | Circulation1998，，10： | 2 |
| 7 | Effect of high temperature and cooling conditions on aerated concrete properties显示文摘 | Leyla Tanacan Halit Yasa Ersoy Urnit Arpacioglu | 2009 | Construction Building Mater2009，，23： | 1 |
| 8 | Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus显示文摘 | Giyasettin Baydas Halit Canatan Abdulbaki Turkoglu | 2002 | Journal of Pineal Research2002，324，： | 1 |
| 9 | Trade openness and economic growth: a cross-country empirical investigafion显示文摘 | Halit Yanikkaya | 2003 | Joumal of Development Economics2003，72，： | 1 |
| 10 | Association of fibrinogen with cardlo-vasocular risk factors and cardiovascular disease in the framingham off- spring population显示文摘 | James JS Halit S Geoffrey HT et el | 2000 | Circulation2000，102，： | 1 |
| 11 | Association of fibrinogen with cardio-vascular risk factors and cardiovascular disease in the framingham off- spring populatlon显示文摘 | James JS Halit S Geoffrey HT | 2000 | Circulation2000，102，： | 1 |
| 12 | Midterm outcome after unilateral approach for bilateraldecompression of lumbar spinal stenosis :5 - year prospective study 显示文摘 | Halit R | 2007 | Eur Spine J2007，16，： | 1 |
| 13 | Emotional and learn- ing capability and their impact on product innovativeness and firm performance显示文摘 | ALIE A HALIT K JOHN C B | 2007 | Technovation2007，27，9： | 1 |
| 14 | The effect of curing conditions on compressive strength of ultra high strength concrete with high volume mineral admixtures显示文摘 | HALIT Y | 2007 | Building and Environment2007，42，5： | 1 |
| 15 | Effect of taurolidine on the normal eyelid and conjunctival flora显示文摘 | HALIT O ELIF O SEZIN IL | 2000 | Curr Eye Res2000，21，5： | 1 |
| 16 | Mechanical properties of reactive powder concrete containing high volumes of ground granulated blast furnace slag显示文摘 | Halit Yaz?c? Mert Y. Yard?mc? Hüseyin Yi?iter Serdar Ayd?n Sel?uk Türkel | 2010 | Cement and Concrete Composites2010，，8： | 1 |
| 17 | Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus显示文摘 | Giyasettin B Halit C and Abdulbaki T | 2002 | J Pineal Res2002，32，4： | 1 |
| 18 | Intermittent Claudication: A Risk Profile From The Framingham Heart Study显示文摘 | Joanne M. Murabito Ralph B. D’Agostino Halit Silbershatz Peter W.F. Wilson | 1997 | Circulation1997，，： | 1 |
| 19 | Credit Default Swap Spread and Succession Events显示文摘 | Halit G Floris S Willem PFA | 2007 | Journal of Financial Regulation and Compli- ance2007，15，4： | 1 |
| 20 | Comparison of Jensen's Procedure Combined with Recession of Antagonist Medial Rectus Muscle or Botulinum Toxin Injection into Antagonist Medial Rectus Muscle:Outcome in A Patient with Bilateral Sixth Nerve Palsy显示文摘 | Emel Basar Halit Oguz Nilufer Akova | | 0，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员