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45篇 您的检索式:作者名="Halfdanarson"
    题名 作者 年代 出处 被引量
1Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation.Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon 2012World Journal of Gastrointestinal Oncology2012,4,5:5
2Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors显示文摘Halfdanarson TR Rubin J Farnell MB 2008Endocr Relat Cancer2008,15,2:1
3Pancreatic neuroendocrine tumors (PNETs): incidence, prognosis and recent trend toward improved survival显示文摘Halfdanarson TR Rabe KG Rubin J 2008Ann Oncol2008,19,5:1
4A sin- gle-institution experience with 491 cases of small bowel adeno- carcinoma显示文摘Halfdanarson TR McWilliams RR Donohue JH 2010Am J Surg2010,199,6:1
5A single-institution experience with 491 cases of small bowel adenocarcinoma显示文摘Thorvardur R. Halfdanarson Robert R. McWilliams John H. Donohue J. Fernando Quevedo 2010The American Journal of Surgery2010,,6:1
6A non-chemotherapy treatment of a primary effusion lymphoma: Durable remission after intracavitary cidofovir in HIV negative PEL refractory tochemotherapy显示文摘Halfdanarson TR Markovic SN Kalokhe U 2006Ann Oncol2006,17,12:1
7Pancreatic endocrine neoplasms:epidemiology and prognosis of pancreatic endocrine tumors显示文摘Halfdanarson TR Rubin J Farnell MB 2008Endocr Relat Cancer2008,15,2:1
8Hematological manifes- tations of copper deficiency: a retrospective review显示文摘Halfdanarson TR Kumar N Li CY 2008Eur J Haematol2008,80,:1
9Copper deficiency in celiac disease显示文摘Halfdanarson TR Kumar N Hogan WJ 2009J Clin Gastroenterol2009,43,:1
10Pancreatic neuroendo- crine tumors (PNETs) : incidence, prognosis and recent trend to- ward improved survival显示文摘Halfdanarson TR Rabe KG Rubin J 2008Ann Oncol2008,19,10:1
11Pancreatic neu- roendocrine tumors (PNETs) :incidence,prognosis and re- cent trend toward improved survival 显示文摘Halfdanarson TR Rabe KG Rubin J 2008Ann Oncol2008,19,10:1
12Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors 显示文摘Halfdanarson TR Rubin J Farnell MB 2008Endocr Relat Cancer2008,15,2:1
13A singleinstitution experience with 491 cases of small bowel adenocarcinoma显示文摘Halfdanarson TR Mc Williams RR Donohue JH 2010Am J Surg2010,199,6:1
14A single-institution experience with 491 cases of small bowel adenocarcinoma 显示文摘Halfdanarson T R McWilliams R R Donohne J H 2010Am J Surg2010,199,6:1
15Pancreatic endo- crine neoplasms: epidemiology and prognosis of pancreatic endo- crine tumors 显示文摘Halfdanarson T R Rubin J Farnell M B 2008Endocr Relat Cancer2008,15,2:1
16Pancreatic neuroendocrine tumors (PNETs): incidence, prognosis and recent trend to-ward improved survival显示文摘Halfdanarson TR Rabe KG Rubin J 2008Ann Oncol2008,19,10:1
17Pancreatic endocrine neoplasms: epidemiology and prognosis of pan- creatic endocrine tumors 显示文摘Halfdanarson TR Rubin J Farnell MB 2008Endocrine-related cancer2008,15,2:1
18Pancreatic neuroendocrine tumors (PNETs):incidence,prognosis and recent trend toward improved survival显示文摘Halfdanarson TR Rabe KG Rubin J et a1 2008Annals of Oncology2008,19,10:1
19Pancreatic endocrine neoplasms:epidemiology and prognosis of pancreatic endocrine tumors显示文摘Halfdanarson TR Rubin J Farnell MB 0,,:1
20Pancreaticneuroendocrine tumors (PNETs): incidence, prognosis and recent trend toward improved survival 显示文摘Halfdanarson TR Rabe KG Rubin J 2008Ann Oncol2008,19,10:1
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