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125篇 您的检索式:作者名="Haifeng Feng"
    题名 作者 年代 出处 被引量
1One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system显示文摘Haifeng Wan Chunjing Feng Fei Teng Shihua Yang Baoyang Hu Yuyu Niu Andy Peng Xiang Weizhen Fang Weizhi Ji Wei Li Xiaoyang Zhao Qi Zhou 2015Cell Research2015,25,2:39
2The impacts of climate change on the Neolithic cultures of Gansu-Qinghai region during the late Holocene Megathermal显示文摘Holocene Megathermal 被划分成早、中间、迟了的时期,各由于他们改变趋势的不同气候在过时的文化上有不同影响。这研究基于在金海·莱克,记录的环境进化信息的比较分析黄土高原和 Zoige 和 Gansu-Qinghai 区域的过时的地点的空间分发的西方的边。结果证明早、中间的时期向温暖、潮湿在 Gansu-Qinghai 区域作为主要扇区与农业支持了过时的文化的开发,而且, Yangshao 文化繁荣的一个全盛时期出现了。Holocene 在 Gansu-Qinghai 区域在 5.9 ka BP 在冷气候事件以后进入了迟了的时期。后来,气候开始变得冷。然而,在 5.84.2 ka BP,相对稳定的温暖、潮湿的气候在这个区域为过时的年龄的 Majiayao 文化的发展创造了条件,因此,它的文化遗产地点的分发向高高度和高纬度膨胀了。从 4.2 ka BP 向前,气候变得冷、干燥,它在 Gansu-Qinghai 区域的过时的文化上有重要影响,在 4.2 ka BP 附近在文化人物和 Qijia 文化的空间分发导致一个戏剧的变化。在以后一将近 300 年冷、干燥的时期,统一过时的耕作文化完全崩溃了。以后,畜牧和耕作和地区性的多重文化的一个工业部门形成了,并且最终导致了原始社会并且开始一个使文明的社会的结束。LIU Fenggui ZHANG Yili FENG Zhaodong HOU Guangliang ZHOU Qiang ZHANG Haifeng 2010Journal of Geographical Sciences2010,20,3:18
3Birth of fertile bimaternal offspring following intracytoplasmic injection of parthenogenetic haploid embryonic stem cells显示文摘Zhikun Li Haifeng Wan Guihai Feng Leyun Wang Zhengquan He YukaiWang Xiu-Jie Wang Wei Li Qi Zhou Baoyang Hu 2016Cell Research2016,26,1:15
4Comprehensive eco-environmental effects of the shelter-forest ecological engineering along the Tarim Desert Highway显示文摘In this work, we report a comprehensive study about the eco-environmental effects of the shelter forest along the Tarim Desert Highway, including the effects on aeolian environment, soil, micro-climate, biodiversity, and groundwater. The results show that: (1) The movement of windblown sand near the ground surface was affected by the shelter forest. The wind speed and sediment transport rate in the shelter forest decreased by 64%―80% and 87.45%―99.02%, respectively. In addition, there were also significant changes in the sand flux structure, the sand grain size, and the deflation and deposition on the ground surface. (2) Compared to the natural mobile sand, the soil bulk density in the forest area decreased while the total salt content, the total porosity, and the water content increased. In addition, the soil fertility was significantly improved in the forest area, and showed the 'first rapid, then slow' variation pattern. (3) The shelter forest showed positive effects on the micro-climate. Within the 6 m height above the ground, the air temperature in the shelter forest at different heights was lower than that in the mobile sand, while the air humidity was higher, while, the soil temperature was also lower in the shelter forest than mobile sand. (4) The number of soil microbial species increased significantly with the improvement of habitat in the shelterbelt. However, the population of different species was not distributed evenly across the surveyed area. (5) Currently, no significant effects of groundwater-pumping and forest-irrigation water have been found on the groundwater level and its salinity. The variation amplitude of both groundwater level and salinity was at the level of centimeters and 1g/L, respectively. No obvious variation trend has been observed.LEI JiaQiang LI ShengYu JIN ZhengZhong FAN JingLong WANG HaiFeng FAN DongDong ZHOU HongWei GU Feng QIU YongZhi XU Bo 2008Chinese Science Bulletin2008,53,S2:14
5Ablation and radar-wave transmission performances of the nitride ceramic matrix composites显示文摘The 2.5 dimensional silica fiber reinforced nitride matrix composites (2.5D SiO2f/Si3N4-BN) were prepared through the preceramic polymer impregnation pyro- lysis (PIP) method. The ablation and radar-wave transparent performances of the composite at high temperature were evaluated under arc jet. The composition and ablation surface microstructures were studied by X-ray diffraction (XRD) and scanning electron microscope (SEM). The results show that the 2.5D SiO2f/Si3N4-BN composites have a linear ablation rate of 0.33 mm/s and high radar-wave trans- parent ratio of 98.6%. The fused layer and the matrix are protected by each other, and no fused layer accumulates on the ablation surface. The nitride composite is a high-temperature ablation resistivity and microwave transparent material.JIANG YongGang ZHANG ChangRui CAO Feng WANG SiQing HU HaiFeng QI GongJin 2008Science China(Technological Sciences)2008,51,1:14
6Parthenogenetic haploid embryonic stem cells produce fertile mice显示文摘Haifeng Wan Zhengquan He Mingzhu Dong Tiantian Gu Guan-Zheng Luo Fei Teng Baolong Xia Wei Li Chunjing Feng Xin Li Tianda Li Ling Shua Rui Fu Liu Wang Xiu-Jie Wang Xiao-Yang Zhao Qi Zhou 2013Cell Research2013,23,11:13
7CO2 Electroreduction in Ionic Liquids: A Review显示文摘Jianpeng Feng Shaojuan Zeng Jiaqi Feng Haifeng Dong Xiangping Zhang 2018Chinese Journal of Chemistry2018,36,10:11
8Successful generation of cloned mice using nuclear transfer from induced pluripotent stem cells显示文摘Shuya Zhou Chenhui Ding Xiaoyang Zhao Eryao Wang Xiangpeng Dai Lei Liu Wei Li Zichuan Liu Haifeng Wan Chunjing Feng Tang Hai Liu Wang Qi Zhou 2010Cell Research2010,20,7:10
9Insulin improves cardiac myocytes contractile function recovery in simulated ischemia-reperfusion:Key role of Akt显示文摘The present study examined cardiac myocytecontractile and Ca2+ transient responses to insulin duringsimulated ischemia/reperfusion (I/R) and furtherinvestigated the role of protein kinase B (Akt) in the insulin-induced inotropic effect. Ventricular myocytes wereenzymatically isolated from adult Sprague-Dawley rats and perfused with Tyrode solution while electrically field-stimulated. Simulated I/R was induced by perfusing the cells with chemical anoxic solution including sodiumcyanide-sodium lactate for 15 min followed by reperfusionwith normal oxygenated Tyrode solution with or withoutinsulin. It is found that insulin only at concentration as high as 10 IU/L could increase cell shortening (16±5%, P < 0.05) in normal myocytes, whereas it concentration-dependently (0.01—10 IU/L) increased the contraction,the velocity ofshortening/releng- thening and Ca2+ transient in I/Rmyocytes. In addition, insulin treatment (1 IU/L) increasedAkt phosphorylation of I/R cardiomyocytes by 2.4-foldcompared with that of the control (P < 0.01). Mostimportantly, pretreatment with LY 294002, a specificinhibitor of phosphatidylinositol 3′-kinase (PI3-kinase), significantly inhibited both Akt phosphorylation and thepositive inotropic response to insulin in the I/Rcardiomyocytes. These results suggest that insulin exertsdirect positive inotropic effect by increasing Ca2+ transient of cardiomyocytes, which is enhanced in the pathologicalcondition of I/R. Akt activation plays an important role inthe insulin-induced improvement of myocyte contractile function following I/R.ZHANG Bo, ZHANG Haifeng, FAN Qian, MA Xinliang & GAO Feng Department of Physiology, The Fourth Military Medical University,Xi抋n 710032, China Correspondence should be addressed to Gao Feng (e-mail: fgao@fmmu.edu.cn) 2003Chinese Science Bulletin2003,48,13:9
10Generation of fertile offspring from Kitw/Kitwv mice through differentiation of gene corrected nuclear transfer embryonic stem cells显示文摘Yan Yuan Quan Zhou Haifeng Wan Bin Shen Xuepeng Wang Mei Wang Chunjing Feng Mingming Xie Tiantian Gu Tao Zhou Rui Fu Xingxu Huang Qi Zhou Jiahao Sha Xiao-Yang Zhao 2015Cell Research2015,25,7:7
11Cascade effects of crop species richness on the diversity of pest insects and their natural enemies显示文摘Understanding how plant species richness influences the diversity of herbivorous and predatory/parasitic arthropods is central to community ecology.We explore the effects of crop species richness on the diversity of pest insects and their natural enemies.Using data from a four-year experiment with five levels of crop species richness,we found that crop species richness significantly affected the pest species richness,but there were no significant effects on richness of the pests’natural enemies.In contrast,the species richness of pest insects significantly affected their natural enemies.These findings suggest a cascade effect where trophic interactions are strong between adjacent trophic levels,while the interactions between connected but nonadjacent trophic levels are weakened by the intermediate trophic level.High crop species richness resulted in a more stable arthropod community compared with communities in monoculture crops.Our results highlight the complicated cross-trophic interactions and the crucial role of crop diversity in the food webs of agro-ecosystems.SHI PeiJian HUI Cang MEN XingYuan ZHAO ZiHua OUYANG Fang GE Feng JIN XianShi CAO HaiFeng LI B.Larry 2014Science China(Life Sciences)2014,57,7:6
12Numerical Analysis of Nd:YAG Pulsed Laser Polishing CVD Self-standing Diamond Film显示文摘Chemical vapor deposited(CVD) diamond film has broad application foreground in high-tech fields.But polycrystalline CVD self-standing diamond thick film has rough surface and non-uniform thickness that adversely affect its extensive applications.Laser polishing is a useful method to smooth self-standing diamond film.At present,attentions have been focused on experimental research on laser polishing,but the revealing of theoretical model and the forecast of polishing process are vacant.The paper presents a finite element model to simulate and analyze the mechanism of laser polishing diamond based on laser thermal conduction theory.The experimental investigation is also carried out on Nd:YAG pulsed laser smoothing diamond thick film.The simulation results have good accordance with the results of experimental results.The temperature and thermal stress fields are investigated at different incidence angles and parameters of Nd:YAG pulsed laser.The pyramidal-like roughness of diamond thick film leads to the non-homogeneous temperature fields.The temperature at the peak of diamond film is much higher than that in the valley,which leads to the smoothing of diamond thick film.The effect of laser parameters on the surface roughness and thickness of graphite transition layer is also carried out.The results show that high power density laser makes the diamond surface rapid heating,evaporation and sublimation after its graphitization.It is also found that the good polish quality of diamond thick film can be obtained by a combination of large incident angle,moderate laser pulsed energy,large repetition rate and moderate laser pulse width.The results obtained here provide the theoretical basis for laser polishing diamond film with high efficiency and high quality.XU Feng HU Haifeng ZUO Dunwen XU Chun QING Zhenghua WANG Min 2013Chinese Journal of Mechanical Engineering2013,26,1:6
13Asymmetric Catalysis with Chiral Frustrated Lewis Pairs显示文摘The chemistry of frustrated Lewis pairs(FLPs)provides the most important approach for the metal-free hydrogenation and hydrosilylations.Great progress has been achieved in this area for the past decade.Some promising results have also been obtained.This perspective article mainly focuses on the recent advances for the synthesis of chiral Lewis acidic boranes in category of three protocols,1)hydroboration of chiral internal alkenes with Piers'borane HB(C6F5)2;2)in situ hydroboration of chiral alkenes or alkynes without any purification;3)and substitution reaction of(C6F5)nBCl3-n with chiral organometallic reagents,as well as their applications in the metal-free asymmetric hydrogenations and hydrosilylations.Wei Meng Xiangqing Feng Haifeng Du 2020Chinese Journal of Chemistry2020,38,6:5
14The compensatory phenomenon of the functional connectome related to pathological biomarkers in individuals with subjective cognitive decline显示文摘Background Subjective cognitive decline(SCD)is a preclinical stage along the Alzheimer’s disease(AD)continuum.However,little is known about the aberrant patterns of connectivity and topological alterations of the brain functional connectome and their diagnostic value in SCD.Methods Resting-state functional magnetic resonance imaging and graph theory analyses were used to investigate the alterations of the functional connectome in 66 SCD individuals and 64 healthy controls(HC).Pearson correlation analysis was computed to assess the relationships among network metrics,neuropsychological performance and pathological biomarkers.Finally,we used the multiple kernel learning-support vector machine(MKL-SVM)to differentiate the SCD and HC individuals.Results SCD individuals showed higher nodal topological properties(including nodal strength,nodal global efficiency and nodal local efficiency)associated with amyloid-βlevels and memory function than the HC,and these regions were mainly located in the default mode network(DMN).Moreover,increased local and medium-range connectivity mainly between the bilateral parahippocampal gyrus(PHG)and other DMN-related regions was found in SCD individuals compared with HC individuals.These aberrant functional network measures exhibited good classification performance in the differentiation of SCD individuals from HC individuals at an accuracy up to 79.23%.Conclusion The findings of this study provide insight into the compensatory mechanism of the functional connectome underlying SCD.The proposed classification method highlights the potential of connectome-based metrics for the identification of the preclinical stage of AD.Haifeng Chen Xiaoning Sheng Caimei Luo Ruomeng Qin Qing Ye Hui Zhao Yun Xu Feng Bai 2020Translational Neurodegeneration2020,9,2:5
15A novel microwave absorber——BaAl_2Fe_(10)O_(19)/poly(m-toluidine) composite:Preparation and electromagnetic properties显示文摘BaFe10Al2O19 /poly(m-toluidine)(BFA/PMT) composites were synthesized by in-situ polymerization of m-toluidine in the presence of BaFe10Al2O19 particles.The structure,composition and morphology of the obtained samples were characterized by using XRD,FT-IR,UV-visible spectroscopy,SEM and TEM techniques.Their electrical conductivity,magnetic property and microwave absorbing property were measured by the four-probe meter,the vibrating sample magnetometer and the vector network analyzer,respectively.The results indicated that BFA particles were coated effectively by PMT polymer and some interactions between PMT and BFA particles existing in the composites.The conductivity of BFA/PMT composite is smaller than that of pure polymers and its saturation magnetization is a little smaller than that of pure BFA.The influence of the constitution and film thickness of absorbent on its microwave absorbing property is evident.The microwave absorbing properties of the BFA/PMT composites are better than those of pure BFA and PMT.When optimizing the mass rate of BFA/PMT to 0.3,the absorbent with 2 mm film thickness has the minimum reflection loss of 28.26 dB at approximate 14.24 GHz,and the maximum available bandwidth of 8.8 GHz,respectively.The results show that these composites can be used as advancing absorption and shielding materials due to their favorable microwave absorbing property.CHEN KeYu XU QingQing LI LiangChao GONG PeiJun CHEN HaiFeng XIAO QiuShi Xu Feng 2012Science China Chemistry2012,55,7:4
16Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs显示文摘Blastocyst complementation by pluripotent stem cell(PSC)injection is believed to be the most promising method to generate xenogeneic organs.However,ethical issues prevent the study of human chimeras in the late embryonic stage of development.Primate embryonic stem cells(ESCs),which have similar pluripotency to human ESCs,are a good model for studying interspecies chimerism and organ generation.However,whether primate ESCs can be used in xenogenous grafts remains unclear.In this study,we evaluated the chimeric ability of cynomolgus monkey(Macaca fascicularis)ESCs(cmESCs)in pigs,which are excellent hosts because of their many similarities to humans.We report an optimized culture medium that enhanced the anti-apoptotic ability of cmESCs and improved the development of chimeric embryos,in which domesticated cmESCs(D-ESCs)injected into pig blastocysts differentiated into cells of all three germ layers.In addition,we obtained two neonatal interspecies chimeras,in which we observed tissue-specific D-ESC differentiation.Taken together,the results demonstrate the capability of D-ESCs to integrate and differentiate into functional cells in a porcine model,with a chimeric ratio of 0.001-0.0001 in different neonate tissues.We believe this work will facilitate future developments in xenogeneic organogenesis,bringing us one step closer to producing tissue-specific functional cells and organs in a large animal model through interspecies blastocyst complementation.Rui Fu Dawei Yu Jilong Ren Chongyang Li Jing Wang Guihai Feng Xuepeng Wang Haifeng Wan Tianda Li Libin Wang Ying Zhang Tang Hai Wei Li Qi Zhou 2020Protein & Cell2020,11,2:4
17Topographical changes of ground surface affected by the shelterbelt along the Tarim Desert Highway显示文摘To study the effects of sand protection project on modern aeolian landform, the types, distribution, and intensity of topographical changes of the ground surface affected by the shelterbelt along the Tarim Desert Highway were determined by measuring the deflation and deposition of sand surface in the Tazhong area located in the hinterland of the Taklimakan Desert. The results showed that (1) the newly-formed landform in sand protection systems is dominated by aeolian deposition including the small-scale Nabkha Dunes, the medium-scale sheet-like sand deposition and the large-scale ridge-like sand deposition. To some degree, aeolian deflation landform can also be formed in the open space in the shelterbelt. Furthermore, it is difficult for aeolian deflation landform to develop in a large scale in the interdunes. However, aeolian deflation landform can be developed in a large-scale on the windward slope of secondary dunes in longitudinal complex sand ridges; (2) on the windward side of the sand protection systems, both the morphology and strike of dwarf mobile dunes in the interdunes are changed by the sand-obstructing forest belts and the ridge-like sand deposition around it. The wind- ward slope of the ridge-like deposition around the sand-obstructing forest belt forms a stable ground surface. After being damaged by forward-moving dunes in a short period, the ground surface is re- covered gradually; (3) on the leeward side of the sand protection systems, aeolian deflations are formed widely. Particularly, the deflation depression is formed in the interdunes. In addition, the dunes in the region with highly topographic relief are cut flat by aeolian deflations; thereafter its relief of to- pography is reduced. The above analysis indicates that shelterbelts have obvious effects on the windward wind-sand flux in terms of dissipating energy and intercepting sand. With the recovery of wind velocity on the leeward side of the sand protection systems, the wind-sand flux gradually tends to be unsaturated; therefore the sand surface deflation is formed.LI ShengYu LEI JiaQiang XU XinWen WANG HaiFeng FAN JingLong GU Feng QIU YongZhi XU Bo GONG Qing ZHENG Wei 2008Chinese Science Bulletin2008,53,S2:4
18Dinoflagellate cysts in recent marine sediment from Guangxi, China显示文摘Total of 33 species of dinoflagellate cysts were discovered from surface sediment in the searegion of Guangxi, among them 12 cyst types (Diplopsalopsis sp. 1, D. sp.2, D. sp.3, Cochlodiniumsp., Protoperidinium sp. 1, P. sp. 2, P.compressum, Scrippsiella sp. 1, S. sp. 2, Alexandriumsp. 1, A. sp. 2, A. sp. 3) were first reported from the South China Sea. And one cyst type(Cochlodinium sp. ) was first reported in the world. Scrippsiella trochoidea is the dominant species inthis area, accounting for 45 % of all the cysts. There are 2 cysts of toxic dinoflagellate (Alexandriumtamarensis and Gymnodinium catenatum ). But there is no relationship between cyst number and grainsize distribution.Haifeng Gu, Qi Fang, Jun Sun, Dongzhao Lan, Feng Cai, Zhiyong Gao Third Institute of Oceanography, State Oceanic Administration, Xiamen 361005,China. E-mail:Haifenggu@yahoo. comCollege of Marine Life Science, Ocean University of China, Qingdao 266003, China. 2003Acta Oceanologica Sinica2003,22,3:4
19Coexistence Analysis between 5G System and Fixed- Satellite Service in 3400-3600 MHz显示文摘The 3400-3600 MHz band is one of the most important candidate frequency bands for the rollout of 5 G system. However, the coexistence between 5 G system and fixed-satellite service(FSS) in this frequency band is one of the most challenging problems for both academic researchers and industry engineers. In this paper, the saturation interference from 5 G base stations to the existing FSS above 3600 MHz is analyzed and the coexistence solution is achieved, which can reduce the interference and guarantee the coexistence between 5 G system and FSS. Furthermore, the Monte Carlo simulation, laboratory test and field test are carried out to verify the coexistence solution.Results show that an isolation distance of 1-2 km is required to avoid the saturation interference in terms of the adjacent bands scenario.To further reduce the isolation distance to 50 m, additional isolation of 35 dB will be necessary, which can be fulfilled by installing a filter at the input port of LNB from a real implementation perspective.Haifeng Tan Yanjie Liu Zhiyong Feng Qixun Zhang 2018China Communications2018,15,11:4
20DID Code:A Bridge Connecting the Materials Genome Engineering Database w让h Inheritable Integrated Intelligent Manufacturing显示文摘A data identifier(DID)is an essential tag or label in all kinds of databases—particularly those related to integrated computational materials engineering(ICME),inheritable integrated intelligent manufacturing(I3M),and the Industrial Internet ofThings.With the guidance and quick acceleration of the developme nt of advanced materials,as envisioned by official documents worldwide,more investigations are required to construct relative numerical standards for material informatics.This work proposes a universal DID format consisting of a set of build chains,which aligns with the classical form of identifier in both international and national standards,such as ISO/IEC 29168-1:2000,GB/T 27766-2011,GA/T 543.2-2011,GM/T 0006-2012,GJB 7365-2011,SL 325-2014,SL 607-201&WS 363.2-2011,and QX/T 39-2005.Each build chain is made up of capital letters and numbers,with no symbols.Moreover,the total length of each build chain is not restricted,which follows the formation of the Universal Coded Character Set in the international standard of ISO/IEC 10646.Based on these rules,the proposed DID is flexible and convenient for extendi ng and sharing in and between various cloud-based platforms.Accordingly,classical two-dimensional(2D)codes,including the Hanxin Code,Lots Perception Matrix(LP)Code,Quick Response(Q.R)code,Grid Matrix(GM)code,and Data Matrix(DM)Code,can be constructed and precisely recognized and/or decoded by either smart phones or specific machines.By utilizing these 2D codes as the fingerprints of a set of data linked with cloud-based platforms,progress and updates in the composition-processing-structure-property-performance workflow process can be tracked spontaneously,paving a path to accelerate the discovery and manufacture of advanced materials and enhance research productivity,performance,and collaboration.William Yi Wang Peixuan Li Deye Lin Bin Tang Jun Wang Quanmei Guan Qian Ye Haixing Dai Jun Gao Xiaoli Fan Hongchao Kou Haifeng Song Feng Zhou Jijun Ma Zi-Kui Liu Jinshan Li Weimin Liu 2020Engineering2020,6,6:4
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