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| 1 | Improvement of visual acuity based on optical coherence tomography patterns following intravitreal bevacizumab treatment in patients with diabetic macular edema显示文摘AIM:To report the visual outcome based on various patterns of optical coherence tomography(OCT)morphology in diabetic macular edema(DME),following treatment with anti-VEGF intravitreal bevacizumab(IVB)injection.METHODS:Sixty-seven consecutive subjects with centre involving DME underwent intravitreal injection of bevacizumab(1.25 mg/0.05 mL)in this retrospective,comparative,non randomized study.The DME was classified into one of four categories:focal,diffuse,focal cystoid and neurosensory detachment based on OCT.Best corrected visual acuity(BCVA),macular appearance,and OCT findings were used to decide whether the subject should have a repeat injection of intravitreal bevacizumab.Outcome measures were a change in mean BCVA(Snellen converted to logMAR)and central macular thickness(CMT)in each group during the six month follow-up period.RESULTS:The mean BCVA improved to logMAR 0.23at final follow-up from a baseline of 0.32 logMAR(P=0.040)in the focal group,logMAR 0.80 at final follow-up from a baseline of 0.82 logMAR(P=0.838)in the diffuse group,worsened to logMAR 0.53 at final follow-up from a baseline of 0.43 logMAR(P=0.276)in the focal cystoid group,and improved to logMAR 0.79 at final follow-up from a baseline of 0.93 logMAR(P=0.490)in the neurosensory detachment group.The mean CMT before treatment were 298.8±25.03μm in the focal group,310.8±40.6μm in the diffuse group,397.15±31.05μm in the focalcystoid group and 401.03±75.1μm in the neurosensory detachment group.A mean of 2.05(range:1-5)injections in the focal group,1.32(range:1-2)in the diffuse group,2.6(range:1-6)in the focal cystoid group and 2.6(range:1-6)in the neurosensory detachment group were performed during the six month follow-up period.Following intravitreal bevacizumab treatment,vision improved,remained unchanged or worsened in 11,7 and2 subjects in focal group;11,9 and 8 in diffuse group;0,2 and 4 in focal cystoid group and 5,5 and 3 subjects respectively in neurosensory detachment group.CONCLUSION:OCT morpholgy patterns in DME may predict the effects of intravitreal bevacizumab treatment,and patients with focal DME are most likely to benefit from the improvent of visual acuity from this treatment. | Haider R.Cheema Ahmed Al Habash Essam Al-Askar | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 3 |
| 2 | Candida glabrata endophthalmitis treated successfully with caspofungin显示文摘 | Sarria JC Bradley JC Habash R | 2005 | Clin Infect Dis2005，40，9： | 1 |
| 3 | Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production 显示文摘 | Martin A Lee J Kichey T Gerentes D Zivy M Tatout C Dubois F Balliau T Valot B Davanture M Laforgue T T Quillere I Coque M Gallais A Moro M B G Bethencourt L Habash D Z Lea P J Charcosset A Perez P Murigneux A Sakakibara H Edwards K J Hirel B | 2006 | The Plant Cell2006，18，11： | 1 |
| 4 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops 显示文摘 | Miflin B J Habash D Z | 2002 | J Exp Bot2002，53，： | 1 |
| 5 | Sodium chlorite administration in long-evans rats: Reproductive and endocrine effects显示文摘 | Carlton B D Habash D L Basaran A H | 1987 | Environmental Research1987，42，1： | 1 |
| 6 | Recent advances in research on radiofrequency fields and health: 2004-2007 显示文摘 | Habash RW Elwood JM Krewski D | 2009 | J Toxicol Environ Health B Crit Rev2009，12，4： | 1 |
| 7 | Comparison between experimental and theoretical probability of fade for free space optical communication显示文摘 | A A Habash K W Fischer C C Cornish | | 0，，： | 1 |
| 8 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops显示文摘 | Miflin B J Habash D Z | | 0，，370： | 1 |
| 9 | Recent advances in research on radiofrequency fields and health :2004 - 2007显示文摘 | Habash RW Elwood JM Krewski D | 2009 | Toxicol Environ Health B Crit Rev2009，12，4： | 1 |
| 10 | Carbon and nitrogen relationships and signaling:The role of glutamine synthetase and glutamate dehydrogenase in nitreogen assimilation and possililities for improvement in the nitrogen utilization of crops显示文摘 | Ben J Miflin Dimah Z Habash | 2002 | Journal of Experimental Botany2002，53，370： | 1 |
| 11 | Short - term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole - body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity显示文摘 | Winnick J J Sherman WM Habash DL | 2008 | J Clin Endo- crinol Metab2008，93，3： | 1 |
| 12 | The clinical epi- demiology and course of the spectrum of renal diseases asso- ciated with HIV infection显示文摘 | Szczech I A Gupta SK Habash R | 2004 | Kidney lnt2004，66，： | 1 |
| 13 | Rapid detection of Enterobacteriaceae in urine by fluorescent 16s rRNA in situ hybridization on membrane filters 显示文摘 | Habash M Lacroix JM | 1997 | J Clin Methods1997，30，： | 1 |
| 14 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops显示文摘 | Miflin B J Habash D Z | 2002 | Journal of Experimental Botany2002，53，370： | 1 |
| 15 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops显示文摘 | Miflin B J Habash D Z | 2002 | J Exp Bot2002，53，： | 1 |
| 16 | The role of ey- :osolie glutamine synthetase in wheat 显示文摘 | Habash D Z Massiah A J Rong H L | 2001 | Annals of Applied Biology2001，138，： | 1 |
| 17 | Recent advances in research on radiofrequency fields and health:2004-2007显示文摘 | Habash RW Elwood JM KrewskiDj etal | 2009 | J Toxicol Environ Health B Crit Rev2009，12，4： | 1 |
| 18 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops显示文摘 | Miflin B J Habash D Z | 2002 | Journal of Experimental Botany2002，53，370： | 1 |
| 19 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops显示文摘 | Miflin B J Habash D Z | 2002 | Journal of Experimental Botany2002，53，： | 1 |
| 20 | The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops显示文摘 | Miflin B J Habash D Z | 2002 | J Exp Bot2002，53，： | 1 |
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