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	题名	作者	年代	出处	被引量
1	AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma显示文摘Intrahepatic cholangiocarcinomas (ICC) are neoplasms that originate from cholangiocytes and can occur at any level of the biliary tree. Surgical resection is the current therapy of choice for this highly aggressive cancer. However, the 5-year survival still is poor, with high recurrence rates. Due to the intrahepatic growth a signifi cant proportion of patients present with advanced disease and are not candidates for curative surgery or transplantation. The existing palliative options are of limited benefit and there is a great necessity for novel therapeutic options. In this article we review the role of the phosphoinositide 3-kinase(PI3K)/ AKT and extracellular regulated kinase (ERK) signaling pathways in ICC and present new data on the prognostic value of these protein kinases. Finally, we discuss future upcoming therapeutic options based on targeting these signaling pathways.	KJ Schmitz H Lang J Wohlschlaeger GC Sotiropoulos H Reis KW Schmid HA Baba	2007	World Journal of Gastroenterology2007，13，48：	8
2	Power management unit chip design for automobile active-matrix organic light-emitting diode display module显示文摘A power management unit (PMU) chip supplying dual panel supply voltage, which has a low electro-magnetic interference (EMI) characteristic and is favorable for miniaturization, is designed. A two-phase charge pump circuit using external pumping capacitor increases its pumping current and works out the charge-loss problem by using bulk-potential biasing circuit. A low-power start-up circuit is also proposed to reduce the power consumption of the band-gap reference voltage generator. And the ring oscillator used in the ELVSS power circuit is designed with logic devices by supplying the logic power supply to reduce the layout area. The PMU chip is designed with MagnaChip’s 0.25 μm high-voltage process. The driving currents of ELVDD and ELVSS are more than 50 mA when a SPICE simulation is done.	KIM J H PARK J H KIM J H CAO T V LEE T Y BAN H J YANG K KIM H G HA P B KIM Y H	2009	Journal of Central South University2009，16，4：	4
3	Treatment of bipolar disorder 显示文摘	Moller H Nasrallah HA	2003	J Clin Psychiatry2003，64，6：	1
4	Microcystin production by Microcystis aeruginosa exposed to different stages of herbivorous zooplankton 显示文摘	Jang M H Ha K Takamura N	2008	Toxlcon2008，51，：	1
5	An anti-apoptotic protein human survivin is a direct inhibitor of Caspase-3 and-7显示文摘	Sung B J Cho YS Kim H J Ha NC Hwang JI	2001	Biochenistry2001，40，4：	1
6	Changes in mieroeystin production by Microcystis aeruginosa exposed to phytoplanktivorous and omnivorous fish 显示文摘	JANGM H HA K LUCAS MC	2004	Aquatic Toxicology2004，68，1：	1
7	Inhibition of tyrosinase and lipoxygenase activities by resveratrol and its derivatives from seeds of Paeonia lactiflora显示文摘	Kim H J Ha S C Choi S W	2002	Nutraceuticals and Food2002，7，4：	1
8	Radiological features of leiomyomatous tumors of the colon and rectum 显示文摘	Lee S H Ha H K Byun J Y	2000	J Comput Assist Tomogr2000，24，3：	1
9	Properties of dynamically vulcanized EPDM and LLDPE blends显示文摘	Kim K H Cho W J Ha C S	1996	J Appl Polym Sci1996，59，2：	1
10	Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells显示文摘	RHYU D Y YANG Y HA H	2005	J Am Soc Nephrol2005，16，3：	1
11	Cementless alumina-on-a- lumina total hip arthroplasty in patients younger than 50 years:a 5 year minimum follow-up study显示文摘	HA Y C KOO K H JEONG S T	2007	J Arthroplasty2007，22，2：	1
12	Compression properties of dust cake of fine fly ashes from a fluidized bed coal combustor on a ceramic filter 显示文摘	Choi J H Ha S J Jang H J	2004	Powder Technology2004，140，：	1
13	Purification and identification of potentially bioactive peptides from enzyme-modified cheese显示文摘	S S HA ILESELASSIE B H LEE B F GIBBS	1999	Journal of Dairy Science1999，82，8：	1
14	Prediction of collapse in femoral head osteonecrosis:a modified Kerboul method with use of magnetic resonance images显示文摘	HA Y C JUNG W H KIM J R	2006	J Bone Joint Surg Am2006，88，3：	1
15	Hemodynamic determinants of the mitral annulus diastolic velocities by tissue Doppler显示文摘	Nagueh SF Sun H Kopelen HA	2001	J Am Coll Cardiol2001，37，1：	1
16	Effect of carvedilol on survival in severe chronic heart failure显示文摘	Packer M Coats AJ Fowler MB Katus HA Krum H Mohacsi P	2001	N Engl J Med2001，344，：	1
17	Fertilization and developmental competence of bovine oocytes derived from different categories of antral follicles 显示文摘	Pavlok A Lucas HA Niemann H	1992	Mol Reprod Dev1992，31，：	1
18	Web Mining for Distance Education显示文摘	HA H S BAE S M PARK S C	2002	IEEE2002，，2：	1
19	Effect of the catalytic ink preparation method on the performance of polymer electrolyte membrane fuel cells显示文摘	SHIN S J LEE J K HA H Y	2002	J Power Sources2002，106，12：	1
20	Orbital analysis of rotor due to electromagnetic force for switched reluctance motor显示文摘	Ha K H Hong J P	2000	IEEE Transactions on Magnetics2000，36，4：	1

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