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1115篇 您的检索式：作者名="HOWELL R"

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	题名	作者	年代	出处	被引量
1	FK506对实验性卒中疗效的系统评价和Meta分析显示文摘FK506是治疗急性卒中的一种候选用药。决定一种药物是否可以用于临床试验,应当以全面的、无偏倚的动物实验数据的评估为依据,同时还应考虑到这些数据的局限性。这种评估不但应包括药物疗效,而且也应包括药效在体内的特征和局限性。本研究应用系统评价和Meta分析的方法对FK506在卒中动物模型中保护作用的证据进行评价。总共纳入了29个描述了实验步骤的研究,包括1759只动物。结果显示,FK506疗效的点估计值(结局指标的改善)是31.3%[95%CI(0.272-0.354)]。在采用氯胺酮麻醉和短暂性脑缺血的动物实验中,FK506的疗效更高,在使用大鼠,合并其他疾病的动物及仅以梗死面积为疗效指标的实验中,FK506疗效较低。已发表的实验研究质量均接近临床试验标准,但在高质量的研究中,FK506的疗效较低。FK506在实验性脑卒中的研究中,虽然显示出有明显的疗效,但是应注意由于研究质量和可能的发表偏倚等冈素的影响,FK506的疗效可能被过高估计。	Malcolm R Macleod Tori O’Collins Laura L Horky David W Howells Geoffrey A Donnan 段建钢	2006	中国循证医学杂志2006，6，6：	3
2	Primary biliary cir rho sis once rare,now common in the United Kingdom?显示文摘	James OF Bhopal R Howel D		0，，：	2
3	Epidurdl buttor butorphamol does not reduce side effects from epidural morphine after cesarean birth 显示文摘	GAMBLING D R HOWELL P HUBER C	1994	Anesth Analg1994，78，6：	1
4	Origins of breast cancer subtypes and therapeutic implications 显示文摘	Sims AH Howell A Howell S J Clarke R B	2007	Nature Clin Pract Oncol2007，4，12：	1
5	Agrobacterium species opportunistic, avirulent plant symbionts 显示文摘	Harman G E Howell C R Viterbo A Chet I	2004	Nature Reviews2004，2，：	1
6	Cotton seeding preemergence damping-off incited by Rhizopus oryzae and Pythium spp and its biological control with Trichoderma spp显示文摘	Howell C R	2002	Phytopatholohy2002，92，：	1
7	Control of Rhizoctonia solani on cotton seedlings with Pseudomonasfluorescens and with an antibiotic produced by the bacterium 显示文摘	HOWELL C R STIPANOVIC R D	1979	Phytopathology1979，69，：	1
8	Infectious diseases and the liver显示文摘	Talwani R Gilliam BL Howell C		0，，01：	1
9	Irrigation timing by the stress day index method 显示文摘	Hiler E A Howell T A Lewis R B	1974	Transaction of ASAE1974，，17：	1
10	Effect of the angle of the femoral and tibial tunnels in the coronal plane and incremental excision of the posterior cruciate ligament on tension of an anterior cruciate ligament graft:an in vitro study显示文摘	Simmons R Howell SM Hull ML	2003	J Bone Joint Surg(Am)2003，85，6：	1
11	Air-to-air heat pumps operating under frosting conditions on the outdoor coil显示文摘	Howell R H	1986	ASHRAE1986，92，82：	1
12	Growth and mineral absorption by striped bass Monroe saratilis fed a plant feedstuff based diet supplemented with phytase 显示文摘	Papatryphon E Howell R A Soares J H	1999	World Aquac Soc1999，30，：	1
13	The Bowen ratio-energy balance method for estimating latent heat flux of irrigated alfalfa evaluated in a semi-arid,advective environment显示文摘	Todd R W Evett S R Howell T A	2000	Agic For Meteorol2000，103，：	1
14	Trichoderma species-opportunistic, avirulent plant symbionts显示文摘	Harman G E Howell C R Viterbo A	2004	Nature Reviews Microbiology2004，2，1：	1
15	Summer Olympic Tourist Market-Learning from the Paste显示文摘	Pyo S Cook R Howell R L	1988	Tourism Management1988，，2：	1
16	A new type of heteropolyoxometalates formed from lacunary polyoxotungstate ions and europium or yttrium cations显示文摘	HOWELL R C PEREZ F G JAIN S		0，，：	1
17	Factors influencing ferrite/ pearlite banding and origin of large pearlite nodules in a hy- poeutectoid plate steel显示文摘	Thompson W S Howell R P	1992	Mater Sci Technol1992，，8：	1
18	A Sensitivity Studyof Parameters Used in Shrinkage and Creep Prediction Models显示文摘	HOWEL R W LARK R J BARR B I G	2005	Magazine of Concrete Research2005，57，10：	1
19	Mechanisms employed by Trichoderma species in the biological control of plant diseases: the history and evolution of current concepts 显示文摘	HOWELL C R	2002	Plant Diseases2002，87，1：	1
20	Inclusion body hepatitis in chickens 显示文摘	HOWELL J MACDONALD D W CHRISTIAN R G	1970	The Canadian Veterinary Journal1970，11，5：	1

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