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| 1 | TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation显示文摘Transforming growth factor-beta(TGF-β)/bone morphogenetic protein(BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcomes, i.e., skeletal, extra skeletal anomalies, autoimmune, cancer, and cardiovascular diseases. Phosphorylation of TGF-β(I/II) or BMP receptors activates intracellular downstream Smads, the transducer of TGF-β/BMP signals. This signaling is modulated by various factors and pathways, including transcription factor Runx2. The signaling network in skeletal development and bone formation is overwhelmingly complex and highly time and space specific.Additive, positive, negative, or synergistic effects are observed when TGF-β/BMP interacts with the pathways of MAPK, Wnt, Hedgehog(Hh), Notch, Akt/m TOR, and mi RNA to regulate the effects of BMP-induced signaling in bone dynamics. Accumulating evidence indicates that Runx2 is the key integrator, whereas Hh is a possible modulator, mi RNAs are regulators, and b-catenin is a mediator/regulator within the extensive intracellular network. This review focuses on the activation of BMP signaling and interaction with other regulatory components and pathways highlighting the molecular mechanisms regarding TGF-β/BMP function and regulation that could allow understanding the complexity of bone tissue dynamics. | Md Shaifur Rahman Naznin Akhtar Hossen Mohammad Jamil Rajat Suvra Banik Sikder M Asaduzzaman | 2015 | Bone Research2015，3，1： | 53 |
| 2 | Adaptive particle swarm optimization ( APSO ) for multimodal function optimization 显示文摘 | Hossen M S Rabbi F Rahman M M | 2009 | International Journal of Engineering and Technology2009，1，3： | 1 |
| 3 | In vitro-antimicrobial and in vivo cytotoxic activity of some ferrocene derivative bioactive metal complexes of first transition series显示文摘 | Haque M E Rahman M Z Hossen M | 2006 | Pak J App Sciences2006，6，5： | 1 |
| 4 | Effect of Lo Han Kuo (Siraitia grosvenori Swingle ) on Nasal Rubbing and Scratching Behavior in ICR Mice显示文摘 | HOSSEN M A SHINMEI Y JIANG S | 2005 | Biological and Pharmaceutical Bulletin2005，28，2： | 1 |
| 5 | Role of substance P on histamine Ha antagonist-induced scratching behavior in mice 显示文摘 | HOSSEN M A INOUE T SHINMEI Y | 2006 | J Pharmacol Sci2006，100，： | 1 |
| 6 | Nanostruetured macro-mesoporous zirconia impregnated by noble metal for catalytic total oxidation of toluene显示文摘 | TIDAHY H L HOSSEN M SIFFERT S COUSIN R LAMONIER J F ABOUKIS A Su B L GIRAUDON J M LECLERCQ G | 2008 | Catal Today2008，137，24： | 1 |
| 7 | Phospholipase Dcatalyzed synthesis of novel phospholipidphytosterol conjugates显示文摘 | Hossen M Hernandez E | 2004 | Lipids2004，39，8： | 1 |
| 8 | Efficiency of plant growth-promoting rhizobacteria (PGPR) for the enhancement of rice growth显示文摘 | Ashrafuzzaman M Hossen F A Ismail M R | 2009 | African Journal of biotechnology2009，8，7： | 1 |
| 9 | In vitro-anti-micro-bial and in vivo cytotoxic activity of some ferrocene derivativebioactive metal complexes of first transition se-ries 显示文摘 | Haque M E Rahman M Z Hossen M | 2006 | PakJApp Sciences2006，6，5： | 1 |
| 10 | Subband decomposition soft-decision algorithm for heart rate variability analysis in patients with obstructive sleep apnea and normal controls显示文摘 | HOSSEN A GHUNAIMI B A HASSAN M O | 2005 | Signal Processing2005，85，： | 1 |
| 11 | Involvement of histamine H3 receptors in scratching hehaviour in mast cell-deficient mice 显示文摘 | Hossen M A Sugimoto Y Kayasuga R | 2003 | Br J Dermatol2003，149，1： | 1 |
| 12 | In vitroantimicrobial and on vivo cytotoxic activity of some ferrocene derivative bioactive metal complexes of first transition series显示文摘 | Haque M E Rahman M Z Hossen M | 2006 | Pak J App Science2006，6，5： | 1 |
| 13 | The role of chemical mediators in eosinophil infiltration in allergic rhinitis in mice显示文摘 | Kayasuga R Iba Y Hossen M A | 2003 | Int Immunopharmacol2003，3，： | 1 |
| 14 | 罗汉果对ICR小鼠擦鼻和搔抓行为的影响显示文摘分别以组胺诱导ICR小鼠擦鼻、化合物48/80诱导搔抓行为,研究罗汉果对过敏症的作用。 | Hossen M | 2006 | 国际中医中药杂志2006，28，5： | 1 |
| 15 | New criteria for meromorphic p-valent starlike functions显示文摘 | Aouf M K Hossen H M | 1993 | Tsukuba J Math1993，17，： | 1 |
| 16 | Enzyme-catalyzed synthesis of structured phospholipids with conjugated linoleic acid显示文摘 | HOSSEN M HERNANDEZ E | 2005 | Eur J Lipid Sci Technol2005，107，： | 1 |
| 17 | Effect of milling on the content of deoxynivalenol,nivalenol,and zearalenone in Japanese wheat显示文摘 | ZHENG Y HOSSEN S M SAGO Y | 2014 | Food Control2014，40，2： | 1 |
| 18 | Efficiency of plant growth-promoting rhizohacteria (PGPR) for the enhancement of rice growth显示文摘 | Ashrafuzzaman M Hossen F A Ismail M R | 2009 | Afri- can Journal of Biotechnology2009，8，7： | 1 |
| 19 | Long-termfunctional prognosis of posterior in juries in high- energy pelvic disruption显示文摘 | Dujardin F H Hossen baccus M Duparc F | 1998 | J Orthor Trauma1998，12，3： | 1 |
| 20 | Roles of arbitrarily charged heavy ions and degenerate plasma pressure in cylindrical and spherical IA shock waves显示文摘 | M R Hossen L Nahar A A Mamun | 2014 | Physica Scripta2014，，10： | 1 |
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