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| 1 | Endoscopic treatment modalities and outcomes in nonvariceal upper gastrointestinal bleeding显示文摘BACKGROUND In nonvariceal upper gastrointestinal bleeding(NVUGIB),the optimal volume of adrenaline,the optimal number of hemoclips,and the application of thermal coagulation in determining patient outcomes have not been well studied.AIM To demonstrate a dose-response relationship between the commonly used endoscopic modalities for the treatment of non-variceal upper gastrointestinal bleeding and various clinical outcomes.METHODS Patients presenting with NVUGIB were retrospectively identified and analyzed.These patients were stratified as follows:(1)>10 mL of adrenaline injected vs≤10 mL;(2)>1 hemoclip placed vs≤1 hemoclip;(3)Heater probe used or not;and(4)>2 treatment modalities used vs≤2.The primary outcomes were rebleeding and the need for repeat endoscopy.The secondary outcomes were the need for surgery,required transfusions,length of hospital stay,death during the same admission period and 30 d mortality.Patients with NVUGIB who required endoscopic therapy were included.Those who did not require endoscopic therapy or were initially treated with surgery or embolization were excluded.RESULTS In all,501 patients with NVUGIB were treated.One hundred sixty-one(32.1%)patients needed endoscopic therapy.The injection of<10 mL of adrenaline was associated with less rebleeding(P<0.0001),the need for repeat endoscopy(P=0.001)and a decreased length of hospital stay(P=0.026).The use of>2 treatment modalities were associated with increased rebleeding(P=0.009)and the need for repeat endoscopy(P=0.048).The placement of>1 hemoclip was associated with a decreased length of hospital stay(P=0.044).The rates of surgery and death were low,and there were no other significant differences between the patient groups.CONCLUSION The more restrictive use of adrenaline and number of endoscopic modalities to treat NVUGIB with the more liberal use of hemoclips was associated with better patient outcomes. | Benjamin Cherng Hann Yip Hossain Sayeed Sajjad Jie-Xun Wang Constantinos P Anastassiades | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，2： | 2 |
| 2 | Obesity and diabetes in the developing world - a grow- ing challenge显示文摘 | Hossain P | 2007 | N Engl J Med2007，356，3： | 1 |
| 3 | Early dectecti0n of diabetic perpher- al neuropathy with corneal confocal microscopy显示文摘 | Hossain P Sachdev A Malik RA | 2005 | Lancet2005，366，9494： | 1 |
| 4 | Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxi- a-activated HIF-1显示文摘 | Hodges T W Hossain C F Kim Y P | 2004 | J Nat Prod2004，67，： | 1 |
| 5 | Obesity and diabetes in the developing world-a growing challenge显示文摘 | Hossain P Kawar B El Nahas M | 2007 | N Engl 1 Med2007，356，： | 1 |
| 6 | Obesity and diabetes in the developing world-a growing challenge 显示文摘 | Hossain P Kawar B | 2007 | N Engl J Med2007，356，3： | 1 |
| 7 | Optimal channel access man- agement with QoS support for cognitive vehicular networks显示文摘 | NIYATO D HOSSAIN E WANG P | 2011 | IEEE Transactions on Mobile Computing2011，10，5： | 1 |
| 8 | Connexin 43 (cx43)enhances chemotherapy-induced apoptosis in human glioblastoma cells显示文摘 | Huang R P Hossain M Z Huang R | 2001 | Int J Cancer2001，92，： | 1 |
| 9 | The management of retinal vein occlusion:is interventional ophthalmology the way forward显示文摘 | Shahid H Hossain P W M Amoaku | 2006 | Br J Ophthalmol2006，90，5： | 1 |
| 10 | Board composition in New Zealand:An agency perspective显示文摘 | Prevost A K Rao R P Hossain M | 2002 | Journal of Business Finance & Accounting2002，29，56： | 1 |
| 11 | Molecular- targeted antitumor agents: The Saururus cernuus dineolignans manassantin B and 4-O-demethyl-manass- antin B are potent inhibitors of hypoxia-activated HIF-I 显示文摘 | Hodges T W Hossain C E Kim Y P | 2004 | JNatProd2004，67，5： | 1 |
| 12 | Effect of irradiation at the early foetal stag on adult brain function of mouse: leafing and memory 显示文摘 | Hossain M Urea Devi P | 2001 | Int J Radiat Biol2001，77，5： | 1 |
| 13 | Nipah virus en- cephalitis reemergence, Bangladesh显示文摘 | Hsu V P Hossain M J Parashar U D | 2004 | Emerg Infect Dis2004，10，： | 1 |
| 14 | Internal cooling augmentation in rectangular channel using two inclined baffles显示文摘 | DUTTA P HOSSAIN A | 2005 | Int J of Heat and Fluid Flow2005，26，2： | 1 |
| 15 | Obesity and diabe- tes in the developing world a growing challenge显示文摘 | HOSSAIN P KAWAR B EL NAHAS M | 2007 | N En- gl J Med2007，356，： | 1 |
| 16 | The application ofbiotechnology to orchids显示文摘 | Hossain M M Kant R Van P T Winarto B Zeng S J Teixeira da Silva J A | | 0，，02： | 1 |
| 17 | Obesity and diabetes in the developing world-a growing challenge 显示文摘 | Hossain P Kawar B El Nahas M | 2007 | N Engl J Med2007，356，3： | 1 |
| 18 | Nipah virus encephalitis reemergence,Bangladesh显示文摘 | HSU V P HOSSAIN M J PARASHAR U D | 2004 | Emerg Infect Dis2004，10，12： | 1 |
| 19 | Molecular mechanism of heavy metal toxicity and tolerance in plants:central role of glutathione in detoxification of reactive Oxygen species and methylglyoxal and in heavy metal chelation显示文摘 | Hossain M Piyatida P Silva J | 2012 | Journal of Botany2012，14，9： | 1 |
| 20 | Synergic effects of tacrolimus and azole antifungal agents against azoleresistant Candida albican strains 显示文摘 | MAESAKI S MARICHAL P HOSSAIN MA | 1998 | J Antimicrob Chemother1998，42，6： | 1 |
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