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| 1 | Monomethyl fumarate augments NK cell lysis of tumor cells through degranulation and the upregulation of NKp46 and CDIO7a显示文摘Dimethyl fumarate (DMF ) 是使用到对待的新药多重硬化(MS ) 病人。这里,我们在生来的杀手(NK ) 的各种各样的活动检验了 DMF 和 DMF 代谢物 monomethyl fumarate (MMF ) 的效果房间。我们证明 MMF 扩充 K562 和 RAJI 肿瘤房间的主要 CD56 +, 然而并非 CD56 −, NK 房间细胞溶解。MMF 为 24 h 在孵化以后在 CD56 +, 然而并非 CD56 −, NK 房间的表面上导致了 NKp46 表示。这效果密切通过这代谢物从这些房间在 CD56 + NK 房间和 Granzyme B 版本的正式就职的表面上与 CD107a 表示的 upregulation 被相关。anti-NKp46 抗体通过 CD56 + NK 房间禁止了 CD107a 的导致 MMF 的 upregulation 和肿瘤房间的细胞溶解。因此,这些结果是第一证明 MMF 扩充肿瘤目标房间的 CD56 + NK 房间细胞溶解,效果通过 NKp46 调停了。这新奇效果在癌症为治疗学或预防的协议建议 MMF 的使用。 | Heidi Vego Kristin L Sand Rune A Hoglund Lars-Egil Fallang Glenn Gundersen Trygve Holmoy Azzam A Maghazachi | 2016 | Cellular & Molecular Immunology2016，13，1： | 2 |
| 2 | : Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lymphomas 显示文摘 | Hoglund M Sehn L Connors JM | 2004 | Genes Chromosomes Cancer2004，39，： | 1 |
| 3 | DICTRA,a tool for simulation of diffusion transformations in alloys显示文摘 | Borgenstam A Engstrom A Hoglund L | 2000 | Journal of Phase Equilibria2000，21，3： | 1 |
| 4 | Thermo-Calc and DICTRA,computational tools for materials science显示文摘 | Andersson J O Helander T Hoglund L | 2002 | CALPHAD2002，26，2： | 1 |
| 5 | Different myrosinase and idioblast distribution in Arabidopsis and Brassica napus显示文摘 | ANDREASSON E BOLT JORGENSEN L HOGLUND A S | 2001 | Plant Physiol2001，127，4： | 1 |
| 6 | Thermo-calc and Dictra, computational tools for materials science 显示文摘 | Andersson J O Helander T HOglund L etc | 2002 | Calphad2002，26，： | 1 |
| 7 | A tool for simulation of diffusional transformations in alloys 显示文摘 | Borgenstam A Engstron A Hoglund L | 2000 | Phase Equilib2000，21，： | 1 |
| 8 | Seed-specific overexpression of an endogenous arabidopsis phytoene synthase gene results in delayed germination and increased levels of carotenoids, chlorophyll, and abscisic Acid 显示文摘 | Lindgren L O Stalberg K G Hoglund A S | 2003 | Plant Physiol2003，132，： | 1 |
| 9 | Household Demand for Water in Sweden with Implications of A Potential Tax on Water Use 显示文摘 | Hoglund L | 1999 | Water Resources Research1999，35，12： | 1 |
| 10 | Thermo-Calc l & DICTRA,computational tools for materials science显示文摘 | T Helander L Hoglund P Shi | 2002 | Calphad2002，26，2： | 1 |
| 11 | Thermo-Calc 1 & DICTRA,computational tools for materials science显示文摘 | ANDERSON J O HELANDER T HOGLUND L SHI P SUNDMAN B | 2002 | Calphad2002，26，2： | 1 |
| 12 | Household demand for water in Sweden with implications of a potential tax on water use显示文摘 | Hoglund L | 1999 | Water Resource Research1999，35，12： | 1 |
| 13 | Biological half-lives of polybrominated diphenyl ethers and tetrabromobisphenol in exposed workers显示文摘 | Hagmar L Sjodin A Hoglund P | 2000 | Organohalog Compd2000，47，： | 1 |
| 14 | Thermo-Calc and DICTRA-computational tools for materialsscience显示文摘 | Andersson J O Helander T Hoglund L | 2001 | Calphad2001，26，： | 1 |
| 15 | Myrosinase is localized to the interior of myrosin grains and is not associated to the surrounding tonoplast membrane显示文摘 | HOGLUND A S LENMAN M RASK L | 1992 | Plant Science1992，85，： | 1 |
| 16 | Myrosinase is localized to the interior of myrosin grains and is not associated to the surrounding tonoplast membrane显示文摘 | HOGLUND A S LENMAN M RASK L | 1992 | Plant Science1992，85，： | 1 |
| 17 | EuroSCORE predicts in- tensive care unit stay and costs of open heart surgery显示文摘 | Nilsson J Algotsson L Hoglund P | 2004 | Ann Tho- rac Surg2004，78，5： | 1 |
| 18 | Thermo-Calc & DICTRA, computational tools for materials显示文摘 | Andersson J O Helander T Hoglund L | 2002 | Calphad2002，26，： | 1 |
| 19 | Thermo-Calc and Dictra computational tools for materials science显示文摘 | ANDERSON J O HELANDER T HOGLUND L | 2002 | CALPHAD2002，26，2： | 1 |
| 20 | Thermo-calc & DICTRA, computational tools for materials science 显示文摘 | Andersson J O Helander T Hoglund L | 2002 | Calphad2002，26，2： | 1 |
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