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| 1 | β-defensins and the epididymis: contrasting influences of prenatal, postnatal, and adult scenarios显示文摘β -defensins 是主人防卫的部件,与抗菌剂和多种的免疫调节的性质。在最后 15 年的研究表明了许多 β 的丰富的表示;在不同种类的出生后的 epididymis 的 -defensins。这些蛋白质的区域特定、房间特定的表示的一个坡度在出生后的 epididymis 的上皮被观察。他们进到他们沿着 epididymis 旅行的精子的钠液体和绑定的分泌物在繁殖特定的任务建议了他们的参与。因此,连续注意被给了各种各样的 β为他们在精子功能和富饶的角色的 -defensins。尽管 β -defensins 大部分依赖于雄激素,在 epididymis 调整他们的表达式和函数的内在的机制很好没被理解。最近的调查指出了到在哪儿的一种新、有趣的情形 β ; -defensins 在 Wolffian 管与一个不同表示模式出现, epididymis 的胚胎的先锋与成年 epididymis 对比,从而有关 β 的多功能的角色重新定义这个概念;在发展中的 epididymis 的 -defensins 。在这评论,我们总结 β 的一些当前的看法;在在 prenatal-to-postnatal 转变期间在发展中的 epididymis 在他们的角色上加亮我们的最近的数据和推测的 epididymis 的 -defensins ,在可以贡献 epididymal 生物学和男富饶的更好的理解的这个研究区域把注意带到许多未答复的问题。 | Camilla M Ribeiro Erick JR Silva Barry T Hinton Maria Christina W Avellar | 2016 | Asian Journal of Andrology2016，18，2： | 4 |
| 2 | Trends and outcomes of transarterial chemoembolization in hepatocellular carcinoma:a national survey显示文摘BACKGROUND:Transarterial chemoembolization(TACE) is a palliative procedure frequently used in patients with advanced hepatocellular carcinoma(HCC). We examined the national inpatient trends of TACE and related outcomes in the United States over the last decade.METHODS:We utilized the National Inpatient Sample(2002 to 2012) and performed trend analyses of TACE for HCC in all adult patients(age >18 years). Multivariate analyses for the outcomes of in-hospital 'procedure-related complications'(PRCs) and 'post-procedure complications'(PPCs) were performed. We also compared early(2002 to 2006) and late(2007 to 2012) eras by multivariate analyses to identify predictors of complications, healthcare resource utilization and mortality.RESULTS:Overall, 19058 patients underwent TACE for HCC where PRCs and PPCs were seen in 24.2% and 17.6% of patients, respectively. The overall trends in the use of TACE(P<0.001) and associated PRCs(P=0.006) were observed to be increasing. There was less mortality [adjusted Odds ratio(a OR):0.58; 95% CI:0.41, 0.82], reduced length of hospital stay(-1.87 days; 95% CI:-2.77,-0.97) and increased hospital charges($19232; 95% CI:11013, 27451) in the late era. Additionally, there was increased mortality(a OR:4.07; 95% CI:2.96, 5.59), PRCs(a OR:3.21; 95% CI:2.56, 4.02), and PPCs(a OR:2.70; 95% CI:2.11, 3.46) among patients with coagulopathy.CONCLUSIONS:There is an increasing trend of TACE utilization in HCC. However, the outcomes are worse in patients with coagulopathy. Although PRCs have increased, mortality has decreased in recent years. These findings should be considered during TACE evaluation in patients with HCC. | Khalid Mumtaz Nishi Patel Rohan M Modi Vihang Patel Alice Hinton James Hanje Sylvester M Black Somashaker Krishna | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，6： | 2 |
| 3 | MMP-2 and MMP-9 secretion by rpe is stimulated by angiogenic molecules found in choroidal neovascular membranes 显示文摘 | Hoffmann S He S Ehren M Ryan S J Wiedemann P Hinton DR | 2006 | Retina2006，26，4： | 1 |
| 4 | Coliform numbers in the stomach and small intestine of healthy pigs following weaning at three weeks of age 显示文摘 | Hampson D Hinton J M Kidder D E | 1985 | Comp Pathol1985，95，： | 1 |
| 5 | Examining the contribution of glacial till water to storm runoff using two and three-component hy-drograph separations 显示文摘 | Hinton M J Schiff S L English M C | 1994 | Water Resource Research1994，30，： | 1 |
| 6 | Development of polygalacturonase activity and solubilization of pectin in peaches during ripening显示文摘 | Pressey R Hinton D M Avants J K | 1971 | Food Science1971，36，7： | 1 |
| 7 | Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha显示文摘 | Jin M He S Worpel V Ryan SJ Hinton DR | 2000 | Invest Ophthalmol Vis Sci2000，41，13： | 1 |
| 8 | Lamina Properties, Lay -up Configurations and Loading Conditions for a Range of Fibre-reinforced Composite Laminates 显示文摘 | Soden P D Hinton M J Kaddour A S | 1998 | Composites Sci- ence and Technology1998，58，7： | 1 |
| 9 | Dietary mannanoligo- saccharides and their effect on chicken caecal microflora in rela- tion to Salmonella enteritidis colonization 显示文摘 | FERNANDEZ F HINTON M VAN G B | 2002 | Avian Pathology2002，31，1： | 1 |
| 10 | Biological control of Fusarium moniliforme in maize 显示文摘 | Bacon C W Yates I E Hinton D M | 2001 | Environ- mental Health Perspectives2001，109，2： | 1 |
| 11 | Optimization of Trusses Using Genetic Algorithmsfor Dis crete and Continuous Variables显示文摘 | Ghasemi M HintonE WoodR | 1999 | Engineering Computations1999，16，3： | 1 |
| 12 | Evaluation of the effect of mannan-oligosaccharides on the competitive exclusion of Salmonella enteritidis colonization in broiler chicks显示文摘 | Fernandez F Hinton M Gils B V | 2000 | Avian Pathol2000，29，： | 1 |
| 13 | Microphthalmia resulting from MSX2-induced apoptosis in the optic vesicle 显示文摘 | WU LY LI M HINTON DR | 2003 | Invest Ophthal- mol Vis Sci2003，44，6： | 1 |
| 14 | Control of Salmonella infections in broiler chickens by the acid treatment of their feed 显示文摘 | Hinton M Linton A H | 1988 | Veterinary Record1988，123，6： | 1 |
| 15 | Devonian and carboniferous metamorphism in west-central Maine:the muscovite-almandine geobarometer and the staurolite problem revised显示文摘 | Holdaway M J Dutrow B L Hinton R W | 1988 | American Mineralogist1988，73，： | 1 |
| 16 | Scanning electron mi- croscopy of Fusarium moniliforme within asymptomatic corn kernels and kernels associated with equine leukoencephalomalacia显示文摘 | Bacon C W Bennett R M Hinton D M | 1992 | Plant Disease(USA)1992，76，2： | 1 |
| 17 | Inhibition of chicken anaemia virus replication using multiple short-hairpin RNAs 显示文摘 | Hinton T M Doran T J | 2008 | Antiviral Res2008，80，2： | 1 |
| 18 | Conservation of L and 3C proteinase activities across distantly related aphthovimses显示文摘 | Hinton T M Ross-Smith N R S | 2002 | Virology2002，83，： | 1 |
| 19 | Novel Nonpeptide CCK-B Antagonists:Design and Development of Quinazolinone Derivatives as Potent,Selective,and Orally Active CCK-B Antagonists显示文摘 | Padia J K Field M Hinton J | | 0，，07： | 1 |
| 20 | Pattern recognition by B cells: the role of antigen repetitiveness versus Toll-like receptors 显示文摘 | Hinton H J Jegerlehner A Bachmann M F | 2008 | Curr Top Mierobiol Im- munol2008，319，： | 1 |
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