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33篇 您的检索式：作者名="HEICAPPELL R"

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	题名	作者	年代	出处	被引量
1	Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA in testicular tissue of infertile patients显示文摘Aim: To evaluate the quantitative detection of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA as diagnostic parameters in the workup of testicular tissue specimens from patients presenting with non-obstructive azoospemia. Methods: hTR and hTERT mRNA expression were quantified in 38 cryopreserved testicular tissue specimens by fluorescence real-time reverse transcription- polymerase chain reaction (RT-PCR)in a LightCycler(r). This was paralleled by conventional histological workup in all tissue specimens and additional semithin sectioning preparation in cases with maturation arrest ( n = 12) and Sertoli-cell-only syndrome ( n = 12). Results: The average normalized hTERT expression (NhTERT) Was 131.9 ± 48.0 copies (mean ± SD) in tissue specimens with full spermatogenesis, NhTERT = 51.2 ± 17.2 copies in those with maturation arrest and NhTERT = 2.7 ± 2.4 copies in those with Sertoli-cell-only syndrome (SCOS). The discriminant analysis showed that detection of NhTERT (NhTR) had a predictive value of 86.8 % (55.3 % ) for correct classification in one of the three histological subgroups.Conclusion: Our results demonstrate that quantitative detection of hTERT mRNA expression in testicular tissue enables a molecular-diagnostic classification of gametogenesis. Quantitative detection of hTERT in testicular biopsies is thus well suited for supplementing the histopathological evaluation.	Mark Schrader Markus Müller Rüdiger Heicappell Bernd Straub Kurt Miller	2001	Asian Journal of Andrology2001，3，4：	3
2	DNA- based detection of prostate cancer in blood, urine,and ejaculates 显示文摘	Goessl C Muller M Heicappell R Krause H Miller K	2001	Ann N Y Acad Sci2001，945，：	1
3	Quantitative detection of human complement factor H-related protein in transitional cell carcinoma of the urinary bladder显示文摘	Heicappell R Wettig IC Schostak M	1999	Eur Urol1999，35，：	1
4	DNA-based detection of prostate cancer in urine after prostatic massage 显示文摘	Goessl C MUller M Heicappell R	2001	Urology2001，58，3：	1
5	Pneumatic lithotripsy applied through deflected working channel of miniureteroscope results in 143 paitients显示文摘	KNISPEL HH KLAN R HEICAPPELL R	1998	J Endourol1998，12，6：	1
6	Impact of chemotherapy on male fertility显示文摘	Schrader M Heicappell R Muller M	2001	Onkologie2001，24，4：	1
7	Successful application of non-oncogcnic viruses for antimelaslatic cancer immuno therapy显示文摘	SchirrmacherV AhlertT Heicappell R	1986	CancerRev1986，5，：	1
8	Telomerase activity and expression of telornerase subunits in the testicular tissue of infertile patients显示文摘	Schrader M Müller M Heicappell R	2000	Fertil Steril2000，73，4：	1
9	Erythropoietin in urologic oncology显示文摘	Albers P Heicappell R Schwaibold H	2001	Eur Urol2001，39，1：	1
10	Pneumatic lithotripsy applied through deflected working channel of miniureteroscope: results in 143 patients显示文摘	KNISPEL HH KLAN R HEICAPPELL R	1998	J Endourol1998，12，6：	1
11	Impact of chemotherapy on male fertility 显示文摘	Schrader M Heicappell R Muller M	2001	Onkologie2001，24，4：	1
12	DNA-based detection of prostate cancer in urine after prostatic massage显示文摘	Goessl C Muller M Heicappell R	2001	Urology2001，58，：	1
13	Telomerase activity in malignant and benign renal tumors 显示文摘	Muller M Heicappell R Krause H	1999	Eur Urol1999，35，3：	1
14	Telomerase activity and expression of telomerase subunits in the testicular tissue of infertile patients显示文摘	Schrader M Müller M Heicappell R	2000	Fertil Steril2000，73，4：	1
15	Pneumatic lithotripsy applied throughdeflected working channel of miniureteroscope:results in 143patients显示文摘	Knispel H H Klan R Heicappell R	1998	J Endourol1998，12，6：	1
16	Telomerase activity and expression of telomerase subunits in the testicular tissue of infertile patients显示文摘	SCHRADER M MULLER M HEICAPPELL R	2000	Fertil Steril2000，73，4：	1
17	Evalua- tion of urinary bladder cancer antigen as a marker for diagnosis of transitional cell carcinoma of the urinary bladder显示文摘	Heicappell R Schostak M Miiller M	2000	Scand J Clin Lab Invest2000，60，4：	1
18	Pneumatic lithotripsy applied through deflected working channel of miniureteroscope: results in 143 patients显示文摘	KNISPEL H H KLAN R HEICAPPELL R	1998	Endourol1998，12，12：	1
19	Successful Application of Nononcogenic Viruses for Antimetastatic Cancer Immunotherapy显示文摘	Ahlert T Heicappell R	1986	Cancer1986，5，：	1
20	Quantitative detection of human complement factor H- related protein in transitional cell carcinoma of the urinary bladder显示文摘	Heicappell R Wetting I C Schostak M	1999	Eur Urol1999，35，1：	1

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