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504篇 您的检索式:作者名="SCHRADER M"
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1Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA in testicular tissue of infertile patients显示文摘Aim: To evaluate the quantitative detection of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA as diagnostic parameters in the workup of testicular tissue specimens from patients presenting with non-obstructive azoospemia. Methods: hTR and hTERT mRNA expression were quantified in 38 cryopreserved testicular tissue specimens by fluorescence real-time reverse transcription- polymerase chain reaction (RT-PCR)in a LightCycler(r). This was paralleled by conventional histological workup in all tissue specimens and additional semithin sectioning preparation in cases with maturation arrest ( n = 12) and Sertoli-cell-only syndrome ( n = 12). Results: The average normalized hTERT expression (NhTERT) Was 131.9 ± 48.0 copies (mean ± SD) in tissue specimens with full spermatogenesis, NhTERT = 51.2 ± 17.2 copies in those with maturation arrest and NhTERT = 2.7 ± 2.4 copies in those with Sertoli-cell-only syndrome (SCOS). The discriminant analysis showed that detection of NhTERT (NhTR) had a predictive value of 86.8 % (55.3 % ) for correct classification in one of the three histological subgroups.Conclusion: Our results demonstrate that quantitative detection of hTERT mRNA expression in testicular tissue enables a molecular-diagnostic classification of gametogenesis. Quantitative detection of hTERT in testicular biopsies is thus well suited for supplementing the histopathological evaluation.Mark Schrader Markus Müller Rüdiger Heicappell Bernd Straub Kurt Miller 2001Asian Journal of Andrology2001,3,4:3
2Isolation andcharacterization of the circulating form of human endostatin显示文摘 Schrader M Kanse SM 1997FEBS Lett1997,420,23:1
3CXCR4/CXCL12 expres sion and signalling in kidney cancer 显示文摘Schrader A J Lechner O Templin M 2002Br J Cancer2002,86,8:1
4Nitric oxide induced contractile dysfunction is related to a reduction in myocardial energy generation 显示文摘Kelm M Schafer S Dahmann R Dolu B Perings S Decking U K Schrader J Strauer B E 1997Cardiovascular Research1997,36,2:1
5Production of 2-phenylethanol and 2-phenylethylacetate from L-phanylalanine by coupling whole-cell biocatalysis with organophilic pervaporation显示文摘ETSCHMANN M M SELL D SCHRADER J 2005Biotechnol0gy and Bioengineering2005,92,5:1
6CXCR4/CXCL12 expression and signalling in kidney cancer 显示文摘Schrader AJ Lechner O Templin M 2002Br J Cancer2002,86,8:1
7The develop-mental potential of the human oocytes is related to the dissolved content of follicular fluid:association with vascular endothelial growth factor levels and perifollicu-lar blood flow charactcristics显示文摘 Antczak M Schrader R 1997Hum Reprod1997,12,5:1
8A model for exponentially decaying inventories显示文摘GHARE P M SCHRADER S F 1963Journal of Industrial Engineering1963,14,5:1
9A model for exponentially decaying inventories显示文摘Ghare P M Schrader GF 1963Journal of Industrial Engineering1963,,14:1
10Rapid colorimetric determination of nitrate in plant-tissue by nitration of salicylic-acid显示文摘Cataldo D A Maroon M Schrader L E Youngs V L 1975Communications in Soil Science and Plant1975,6,:1
11Applied bioeatalysis for the synthesis of natural flavor compounds-current industrial processes and future prospects显示文摘SCHRADER J ETSCHMANN M M W SELL D 2004Bioteehnology Letters2004,26,6:1
12Applied biocatalysis for the synthesis natural flavour compounds current industrial processes and future prospects显示文摘SCHRADER J ETSCHMANN M W SELL D 2004Biotechnology Letters2004,26,:1
13IL-4 inhibits the production of tnf-α and i1-12 by stat6-dependent and -independent mechanisms显示文摘Levings M K Schrader J W 1999J lmmunol1999,162,9:1
14A rapid bioassay for selective algicides显示文摘SCHRADER K K DE REGT M Q TUCKER C S 1997Weed Technol1997,,11:1
15Risks and sequelae of scleral perforation during peribulbar or retrobulbar anesthesia显示文摘Schrader WF Schargus M Schneider E 2010J Cataract Refract Surg2010,36,6:1
16Spatially explicit modeling of schistosomiasis risk in eastern China based on a synthesis of epi- demiological, environmental and intermediate host genetic data 显示文摘Schrader M Hauffe T Zhang Z 2013PLoS Negl Trop Dis2013,7,7:1
17Energy-dependent loading of amino acids and sucrose into phloem of soybean显示文摘Servaites J C Schrader L E Jung D M 1979Plant Physiol1979,,64:1
18Queer Perspectives on SocialResponsibility in Canadian Schools and Libraries:Analysis andResources显示文摘Schrader A M Wells K 2005School Libraries in Canada2005,,6:1
19Isolation and characterization of the circulating form of human endostatin显示文摘Standker L Schrader M Kanse SM 1997FEBS Lett1997,420,23:1
20Assessment of residual tumours after systemic treatment of metastatic seminoma:18F-2-fluoro-2-deoxy-D-glucose positron emission tomography-meta-analysis of diagnostic value显示文摘Müller J Schrader A J Jentzmik F 2011Urologe A2011,50,3:1
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