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| 1 | MRI阴性药物难治性颞叶癫痫合并抑郁症患者的静息态功能磁共振研究显示文摘背景抑郁症在颞叶癫痫中发生率高达50%~60%,而30%的药物难治性颞叶癫痫患者可表现为头颅核磁共振(MRI)无明显异常,这部分患者相较于伴有海马硬化的药物难治性颞叶癫痫患者出现继发性全面强直阵挛发作的机率更高。因此,MRI阴性药物难治性颞叶癫痫合并抑郁症的患者,生活质量更差、自杀风险更高,更需要癫痫外科手术治疗。 | 朱曦 陈蕾 罗程 Zhu X He Z Luo C | 2018 | 癫痫杂志2018，4，3： | 11 |
| 2 | Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells显示文摘AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth.METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability was assessed in XTT assays. For analysis of cell cycle and cell death,flow cytometry and DAPI staining were applied. Expression of cyclooxygenase-2 (COX-2),p21 and bcl-2 in cells incubated with AA or DHA was examined by real-time RT-PCR. Prostaglandin E2 (PGE2) generation in the presence of AA and DHA was measured using a PGE2-ELISA.RESULTS:AA increased cell growth,whereas DHAreduced viability of LS 174T cells in a time-and dose-dependent manner. Furthermore,DHA down-regulated mRNA of bcl-2 and up-regulated p21. Interestingly,DHA was able to suppress AA-induced cell proliferation and significantly lowered AA-derived PGE2 formation. DHA also down-regulated COX-2 expression. In addition to the effect on PGE2 formation,DHA directly reduced PGE2-induced cell proliferation in a dose-dependent manner. CONCLUSION:These results suggest that DHA can inhibit the pro-proliferative effect of abundant AA or PGE2. | Piet Habbel Karsten H Weylandt Katja Lichopoj Johannes Nowak Martin Purschke Jing-Dong Wang Cheng-Wei He Daniel C Baumgart Jing X Kang | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 3 | A conformationally sensitive GHR antibody : impact on GH signaling and GHR proteolysis显示文摘 | Jiang J Wang X He K Li X Chen C M Sayeski P P Waters M J Frank S J | 2004 | Mol Endocrinol2004，18，12： | 1 |
| 4 | Face recognition using laplacianfaces显示文摘 | HE X F Y AN S C HU Y | 2005 | IEEE Trans on Pattern Analysis anti Machine Intelligence2005，27，3： | 1 |
| 5 | Maps preserving numerical radius of products of self-adjoint operators显示文摘 | He K Hou J C Zhang X L | 2010 | Acta Math Sinca-Eng-lish Series2010，6，： | 1 |
| 6 | Energetics of charged point defects in rutile TiO2 by density functional theory显示文摘 | LI X FINNIS M W HE J BEHERA R K PHILLPOT S R SINNOTT S B DICKEY E C | 2009 | Acta Materialia2009，57，： | 1 |
| 7 | Shape Measurement of Small Objects Using LCD Fringe Projection with Phase Shifting 显示文摘 | C Quan X Y He C F Wang | 2001 | Opt Commun2001，189，13： | 1 |
| 8 | Study of the interaction between terazosin and serum albumin synchronous fluorescence determination of terazosin显示文摘 | Jiang C Q Gao M X He H X | 2002 | Analytica Chimica Acta2002，452，： | 1 |
| 9 | Evolution of pore fractal dimensions for burning porous chars 显示文摘 | He R Xu X C Chen C H | 1998 | Fuel1998，77，： | 1 |
| 10 | Face recognition using Laplacianfaces 显示文摘 | He X F Yah S C Hu Y | 2005 | IEEE Transactions on Pattern Analysis and Machine Intelligence(S0162-8828)2005，27，3： | 1 |
| 11 | Mechanism and experimental verification of degradation of RC beams induced by concrete/rebar Engineering Materials, 2011 bonding failure显示文摘 | He X B Huang F Zhang C Y | 2011 | Key2011，，： | 1 |
| 12 | Modification of membrane surface for anti-biofouling performance: Effect of anti-adhesion and anti-bacteria approaches显示文摘 | Liu C X Zhang D R He Y | 2010 | J Membr Sci2010，346，1： | 1 |
| 13 | An innovative design for using flexible printed coils for magnetostrictive-based longitudinal guided wave sensors in steel strand inspection显示文摘 | Tse P W Liu X C Liu Z H Wu B He C F Wang XJ | 2011 | Smart Materials and Structures2011，20，05： | 1 |
| 14 | Heterogeneous Beliefs, Risk and Learning in a Simple Asset Pricing Model 显示文摘 | Chiarella C He X | 2002 | Computational E-conomics2002，，19： | 1 |
| 15 | Trace mercury(II)detection and separation in serum and water samplesusing a reusable bifunctional fluorescent sensor显示文摘 | He C Zhu W Xu Y Chen T Qian X | 2009 | Ana-lytica Chimica Acta2009，651，2： | 1 |
| 16 | Nanoparticle syn- thesis in microreactors 显示文摘 | Zbao C X He L Z Qiao S Z | 2011 | Chemical Engineering Sclence2011，66，： | 1 |
| 17 | Surface modification of puretitanium treated with B4C at high temperature显示文摘 | He L J Zhang X N Tong C D | 2006 | Surface &Coatings Technology2006，200，9： | 1 |
| 18 | Sensitive and rapid detection of the new Delhi metallo-beta- lactamase gene by loop-mediated isothermal amplification 显示文摘 | Liu W Zou D Li Y Wang X He X Wei X Shao C Li X Shang W Yu K Liu D Li Y Guo J Yin Z Yuan J | 2012 | J Clin Microbiol2012，50，5： | 1 |
| 19 | Crop Diversity for Yield Increase显示文摘 | Li C Y He X H | | 0，，11： | 1 |
| 20 | The Effect of Concentration of 'Dy3 + Ions on Luminescence Properties of Y2 02 S : Dy3 + , Mg2 + , Ti4 + Phosphors 显示文摘 | Huang P He X Q Cui C E | 2013 | Ceramics International2013，40，5： | 1 |
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