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| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | RESEARCH ON THE EVALUATION METHOD OF FRICTION AND LUBRICATION IN DEEP DRAWING显示文摘The deformation characteristic of bland in deep drawing is discussed. It is pointed out that the friction and lubrication conditions in for drawing are different from that in mechanical motion or machine work or other plastic process. The common test methods in laboratories are analyzed. It shows that though all those test methods can test the friction coefficient, the probe test method is most suitable for the research of friction and lubrication and the process in deep drawing, for this method is identical with the actual work condition either from the test principle or deformation status of the blank. Last the successful application in the deep drawing simulator newly developed the the probe method are intro- duced in detail. | D. N. He, X. F. Yin, H. Z. Thao, D. L*, X. Y. Ruan, J. L. Cheng and J. Y. Jiang 1) Shanghai Jiao Tong University, National Die & Mold CAD E. R. C, Shanghai 200030, China 2) Shanghai Vopkswagen Automotive Company Ltd., Shanghai 201805, China Manuscript re | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 13 |
| 3 | 氨氯地平和左旋氨氯地平对高血压患者血管内皮功能的影响显示文摘已证明氨氯地平可改善高血压患者的血管内皮功能,但左旋氨氯地平是否具有类似作用仍存在争议。该研究比较氨氯地平和左旋氨氯地平对高血压患者血管内皮功能的影响,应用体外细胞培养研究其相关作用机制。方法:该研究为一项随机、交叉试验。选取原发性高血压患者24例服用氨氯地平和左旋氨氯地平各6周, | He Y Si D Yang C Ni L Li B Ding M Yang P 罗冬梅 叶鹏 | 2014 | 中华高血压杂志2014，22，4： | 2 |
| 4 | A probabilistic reasoning-based decision support system for selecting remediation technologies for petroleum-contaminated sites 显示文摘 | HE L CHAN C W HUANG G H ZENG G M | 2006 | Expert Systems with Applications2006，30，4： | 1 |
| 5 | One new control model for beam instabilites显示文摘 | He D H | 1999 | Particle Accelerators1999，28，： | 1 |
| 6 | Maps preserving numerical radius of products of self-adjoint operators显示文摘 | He K Hou J C Zhang X L | 2010 | Acta Math Sinca-Eng-lish Series2010，6，： | 1 |
| 7 | Factors affecting the filter paper method for total and matric suction measurements显示文摘 | LEONG E C HE L RAHARDJO H | 2002 | Geotechnieal Testing Journal2002，25，3： | 1 |
| 8 | Biological properties of the chitosan -gelatin sponge wound dressing 显示文摘 | DENG C M HE L Z ZHAO M | 2007 | Carbohydr Polym2007，69，3： | 1 |
| 9 | Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy显示文摘 | Hinton DR Spee C He S Weitz S Usinger W LaBree L | 2004 | Diabetes Care2004，27，3： | 1 |
| 10 | Effects of dimethyl sulfoxide and glycine on cryopreservation induced damage ot plasma membranes and mitochondria to striped bass (Morone saxatilis) sperm显示文摘 | He S Woods L C | 2004 | Cryobiology2004，48，3： | 1 |
| 11 | Parametric optimum analysis of an irreversible regenerative magnetic Brayton refrigeration cycle 显示文摘 | Y L Yang J C Chen J Z He | 2005 | Physica B2005，364，： | 1 |
| 12 | Low-power VLSI design for motion estimation using adaptive pixel truncation显示文摘 | HE Z L TSUI C Y CHAN K K | 2000 | IEEE Transactions on Circuits and Systems for Video Technology2000，10，5： | 1 |
| 13 | Mechanical properties of single crystal tungsten microwhiskers characterized by nanoindentation 显示文摘 | HUANG H WU Y Q WANG S L HE Y H ZOU J HUANG B Y LIU C T | 2009 | Materials Science and Engeering A2009，53，12： | 1 |
| 14 | Narcissus analysis for cooled staring IR system 显示文摘 | He F Y Cui J C Feng S L | 2007 | SPIE2007，6772，67： | 1 |
| 15 | Nanoparticle syn- thesis in microreactors 显示文摘 | Zbao C X He L Z Qiao S Z | 2011 | Chemical Engineering Sclence2011，66，： | 1 |
| 16 | Surface modification of puretitanium treated with B4C at high temperature显示文摘 | He L J Zhang X N Tong C D | 2006 | Surface &Coatings Technology2006，200，9： | 1 |
| 17 | A mixed microscopic meth- od for differentiating seven species of 'Bixie' -related Chinese ma- teria medica显示文摘 | Tang Y N He X C Chen Q L | 2014 | Microsc Res Tech2014，77，1： | 1 |
| 18 | Microstructures and proper- ties of SnZn lead-free solder joints bearing La for electronic pack- aging显示文摘 | Zhang L Han J G He C W | 2012 | IEEE Transactions on Electron Devices2012，59，12： | 1 |
| 19 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 20 | Microstructure and mechanical properties of reactive sputtered nanocrystalline (Ti,AI)N fihns 显示文摘 | HE C L ZHANG J L SONG G H | 2015 | Thin Solid Films2015，584，： | 1 |
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