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您的检索式：作者名="HAYAT Muhammad Abid"
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| 1 | 牧场奶牛蹄叶炎与血液生化指标以及常量元素相关性的分析显示文摘为探究牧场奶牛蹄叶炎与奶牛血液中生化指标的相关性,在哈尔滨市某牧场采集了20个亚临床性蹄叶炎病例,20个慢性蹄叶炎病例以及20个健康牛的血液样本。检测其心功、肝功、肾功和常量元素指标,结果显示:临床性蹄叶炎患病组,慢性蹄叶炎与健康组比较,高密度脂蛋白(HDL)均显著性降低(P<0.05),总胆固醇(TC)均显著性升高(P<0.05),尿酸(UA)显著性升高(P<0.05);亚临床蹄叶炎患病组奶牛与健康组比较,磷(P)显著性降低(P<0.05),但慢性蹄叶炎患病组奶牛与健康组比较,P无显著性差异(P>0.05);慢性蹄叶炎患病组奶牛与健康组比较,总胆红素(TBILI)显著性升高(P<0.05),但亚临床性蹄叶炎患病组奶牛与健康组比较,TBILI无显著性差异(P>0.05)。说明血清中以上指标的含量变化与蹄叶炎的发病密切相关。 | 张献颢 丁嘉烽 宋乔志 李岳鹏 HAYAT Muhammad Abid 张建涛 王洪斌 | 2020 | 中国兽医学报2020，40，5： | 4 |
| 2 | Development of bis-thiobarbiturates as successful urease inhibitors and their molecular modeling studies显示文摘Bis-thiobarbiturate derivatives 1–15 have been synthesized, characterized by1 HNMR and EI-MS and screened for urease inhibition. All compounds showed various degree of urease inhibitory activity with IC_(50) values ranging 7.45 0.12 74.24 0.81 mmol/L while the standard thiourea behaved normally(IC_(50) = 21.10 0.12). Compounds 1(IC_(50) = 7.45 0.12 μmol/L), 9(IC_(50) = 18.17 1.03 μmol/L) and 13(IC_(50) = 8.61 0.45 μmol/L) showed excellent urease inhibitory activity in the series. Molecular modeling studies were performed to understand the binding site with the bimetallic nickel center of the enzyme.Structure-activity relationship has also been established for these compounds. This study identified bisthiobarbiturate as a novel class of urease inhibitors. | Fazal Rahim Muhammad Ali Shifa Ullah Umer Rashid Hayat Ullah Muhammad Taha Muhammad Tariq Javed Wajid Rehman Aftab Ahmad Khan Obaid Ur Rahman Abid Muhammad Bilal | 2016 | Chinese Chemical Letters2016，27，5： | 2 |
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