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| 1 | Transient elastography(Fibro Scan~?) with controlled attenuation parameter in the assessment of liver steatosis and fibrosis in patients with nonalcoholic fatty liver disease- Where do we stand?显示文摘Non-alcoholic fatty liver disease(NAFLD) is the most common cause of chronic liver disease worldwide. Currently, the routinely used modalities are unable to adequately determine the levels of steatosis and fibrosis(laboratory tests and ultrasonography) or cannot be applied as a screening procedure(liver biopsy). Among the non-invasive tests, transient elastography(Fibro Scan?, TE) with controlled attenuation parameter(CAP) has demonstrated good accuracy in quantifying the levels of liver steatosis and fibrosis in patients with NAFLD, the factors associated with the diagnosis and NAFLD progression. The method is fast, reliable and reproducible, with good intra- and interobserver levels of agreement, thus allowing for population-wide screening and disease follow-up. The initial inability of the procedure to accurately determine fibrosis and steatosis in obese patients has been addressed with the development of the obese-specific XL probe. TE with CAP is a viable alternative to ultrasonography, both as an initial assessment and during follow-up of patients with NAFLD. Its ability to exclude patients with advanced fibrosis may be used to identify low-risk NAFLD patients in whom liver biopsy is not needed, therefore reducing the risk of complications and the financial costs. | Ivana Mikolasevic Lidija Orlic Neven Franjic Goran Hauser Davor Stimac Sandra Milic | 2016 | World Journal of Gastroenterology2016,22,32: | 33 |
| 2 | Preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: What can be done?显示文摘Post-endoscopic retrograde cholangiopancreatographypancreatitis(PEP) is the most common complication of endoscopic retrograde cholangiopancreatography. The incidence of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis varies substantially and is reported around 1%-10%, although there are some reports with an incidence of around 30%. Usually, PEP is a mild or moderate pancreatitis, but in some instances it can be severe and fatal. Generally, it is defined as the onset of new pancreatictype abdominal pain severe enough to require hospital admission or prolonged hospital stay with levels of serum amylase two to three times greater than normal, occurring 24 h after ERCP. Several methods have been adopted for preventing pancreatitis, such as pharmacological or endoscopic approaches. Regarding medical prevention, only non-steroidal anti-inflammatory drugs, namely diclofenac sodium and indomethacin, are recommended, but there are some other drugs which have some potential benefits in reducing the incidence of post-ERCP pancreatitis. Endoscopic preventive measures include cannulation(wire guided) and pancreatic stenting, while the adoption of the early pre-cut technique is still arguable. This review will attempt to present and discuss different ways of preventing post-ERCP pancreatitis. | Goran Hauser Marko Milosevic Davor Stimac Enver Zerem Predrag Jovanovi? Ivana Blazevic | 2015 | World Journal of Gastroenterology2015,21,4: | 22 |
| 3 | Minimally invasive treatment of pancreatic pseudocysts显示文摘A pancreatic pseudocyst(PPC) is typically a complication of acute and chronic pancreatitis, trauma or pancreatic duct obstruction. The diagnosis of PPC can be made if an acute fluid collection persists for 4 to 6 wk and is enveloped by a distinct wall.Most PPCs regress spontaneously and require no treatment, whereas some may persist and progress until complications occur. The decision whether to treat a patient who has a PPC, as well as when and with what treatment modalities, is a difficult one. PPCs can be treated with a variety of methods: percutaneous catheter drainage(PCD), endoscopic transpapillary or transmural drainage, laparoscopic surgery, or open pseudocystoenterostomy. The recent trend in the management of symptomatic PPC has moved toward less invasive approaches such as endoscopic- and image-guided PCD. The endoscopic approach is suitable because most PPCs lie adjacent to the stomach. The major advantage of the endoscopic approach is that it creates a permanent pseudocysto-gastric track with no spillage of pancreatic enzymes. However, given the drainage problems, the monitoring, catheter manipulation and the analysis of cystic content are very difficult or impossible to perform endoscopically, unlike in the PCD approach. Several conditions must be met to achieve the complete obliteration of the cyst cavity.Pancreatic duct anatomy is an important factor in the prognosis of the treatment outcome, and the recovery of disrupted pancreatic ducts is the main prognostic factor for successful treatment of PPC, regardless of the treatment method used. In this article, we review and evaluate the minimally invasive approaches in the management of PPCs. | Enver Zerem Goran Hauser Svjetlana Loga-Zec Suad Kunosi Predrag Jovanovi Dino Crnki | 2015 | World Journal of Gastroenterology2015,21,22: | 18 |
| 4 | Endoscopic retrograde cholangiopancreatography-induced and non-endoscopic retrograde cholangiopancreatographyinduced acute pancreatitis:Two distinct clinical and immunological entities?显示文摘Acute pancreatitis(AP) is common gastrointestinal disease of varied aetiology. The most common cause of AP is gallstones, followed by alcohol abuse as an independent risk factor. With the increased need for invasive techniques to treat pancreatic and bile duct pathologies such as endoscopic retrograde cholangiopancreatography(ERCP), AP has emerged as the most frequent complication. While severe AP following ERCP is rare(0.5%), if it does develop it has a greater severity index compared to non-ERCP AP. Development of a mild form of AP after ERCP is not considered a clinically relevant condition. Differences in the clinical presentation and prognosis of the mild and severe forms have been found between non-ERCP AP and postendoscopic pancreatitis(PEP). It has been proposedthat AP and PEP may also have different immunological responses to the initial injury. In this review, we summarise the literature on clinical and inflammatory processes in PEP vs non-ERCP AP. | Ivana Plavsic Ivana Zitini Ivana Mikolasevic Goran Poropat Goran Hauser | 2018 | World Journal of Gastrointestinal Endoscopy2018,10,10: | 14 |
| 5 | Porous and Ultra-Flexible Crosslinked MXene/Polyimide Composites for Multifunctional Electromagnetic Interference Shielding显示文摘Lightweight,ultra-flexible,and robust crosslinked transition metal carbide(Ti3C2 MXene)coated polyimide(PI)(C-MXene@PI)porous composites are manufactured via a scalable dip-coating followed by chemical crosslinking approach.In addition to the hydrophobicity,anti-oxidation and extreme-temperature stability,efficient utilization of the intrinsic conductivity of MXene,the interfacial polarization between MXene and PI,and the micrometer-sized pores of the composite foams are achieved.Consequently,the composites show a satisfactory X-band electromagnetic interference(EMI)shielding effectiveness of 22.5 to 62.5 dB at a density of 28.7 to 48.7 mg cm−3,leading to an excellent surface-specific SE of 21,317 dB cm^(2)g^(−1).Moreover,the composite foams exhibit excellent electrothermal performance as flexible heaters in terms of a prominent,rapid reproducible,and stable electrothermal effect at low voltages and superior heat performance and more uniform heat distribution compared with the commercial heaters composed of alloy plates.Furthermore,the composite foams are well attached on a human body to check their electromechanical sensing performance,demonstrating the sensitive and reliable detection of human motions as wearable sensors.The excellent EMI shielding performance and multifunctionalities,along with the facile and easy-to-scalable manufacturing techniques,imply promising perspectives of the porous C-MXene@PI composites in next-generation flexible electronics,aerospace,and smart devices. | Zhi-Hui Zeng Na Wu Jing-Jiang Wei Yun-Fei Yang Ting-Ting Wu Bin Li Stefanie Beatrice Hauser Wei-Dong Yang Jiu-Rong Liu Shan-Yu Zhao | 2022 | Nano-Micro Letters2022,14,4: | 12 |
| 6 | Transgenerational Inheritance and Resetting of Stress, Induced Loss of Epigenetic Gene Silencing in Arabidopsis显示文摘作为无柄的有机体,植物需要察觉到并且适应异构的环境并且由改变他们的细胞的生理学,基因规定,和染色体稳定性开发了复杂回答。最近的工作在被建议具有 epigenetic 自然的 plantsa 现象在染色体稳定性的控制上表明了可继承的压力效果。这里,我们证明温度和 UV-B 应力在 Arabidopsis 在沉默记者基因的 epigenetic 控制引起立即、可继承的变化。基因 silencing 的这个调停压力的版本在 histone 占有并且在 histone H3 acetylation 与显著改变相关但是没在 DNA methylation 包含调整。我们在记者基因 silencing 上观察了压力效果的传播到非强调的子孙,但是这效果被限制为由房间的一个小数字组成的区域并且限制了到一些非强调的子孙代。而且,基因 silencing 的导致压力的版本在种子老化期间被反对并且重设。这现象的短暂性质加亮工厂的能力限制 epigenetic 控制机制的导致压力的松驰,它多半贡献保卫染色体完整。 | Christina Lang-Mladek Olga Popova Kathrin Kiok Marc Berlinger Branislava Rakic Werner Aufsatz Claudia Jonak Marie-Theres Hauser Christian Luschnig | 2010 | Molecular Plant2010,3,3: | 11 |
| 7 | Sonography of the small intestine显示文摘In the last two decades, there has been substantial development in the diagnostic possibilities for examining the small intestine. Compared with computerized tomography, magnetic resonance imaging, capsule endoscopy and double-balloon endoscopy, ultrasonography has the advantage of being cheap, portable, flexible and user-and patient-friendly, while at the same time providing the clinician with image data of high temporal and spatial resolution. The method has limitations with penetration in obesity and with intestinal air impairing image quality. The flexibility ultrasonography offers the examiner also implies that a systematic approach during scanning is needed. This paper reviews the basic scanning techniques and new modalities such as contrast-enhanced ultrasound, elastography, strain rate imaging, hydrosonography, allergosonography, endoscopic sonography and nutritional imaging, and the literature on disease-specific findings in the small intestine. Some of these methods have shown clinical benefit, while others are under research and development to establish their role in the diagnostic repertoire. However, along with improved overall image quality of new ultrasound scanners, these methodshave enabled more anatomical and physiological changes in the small intestine to be observed. Accordingly, ultrasound of the small intestine is an attractive clinical tool to study patients with a range of diseases. | Kim Nylund Svein Фdegaard Trygve Hausken Geir Folvik Gülen Arslan Lied Ivan Viola Helwig Hauser Odd-Helge Gilja | 2009 | World Journal of Gastroenterology2009,15,11: | 9 |
| 8 | 棉纤维阳离子改性研究现状及趋势显示文摘总结棉纤维阳离子改性的研究现状和发展趋势。介绍了几种阳离子改性剂的制备方法及特点,分析比较了几种不同棉织物阳离子化处理工艺的优缺点,并就阳离子改性棉的应用及产品开发进行了展望。指出:双活性氯醇季铵盐型棉纤维阳离子改性剂在当前的棉纤维阳离子改性中具有一定优势,发展前景较好。认为对棉进行阳离子改性可实现无盐、低碱染色,提高染料的利用率和染色性能,减少染色工艺流程和废水排放。 | 袁红萍 Peter J Hauser | 2014 | 棉纺织技术2014,42,7: | 7 |
| 9 | Preservation of sperm of cancer patients: extent of use and pregnancy outcome in a tertiary infertility center显示文摘精子 cryopreservation 是最好的形式为与癌症诊断的男性保证未来生育力。cryopreserved 精子实际上为受精,可得到的富饶治疗选择和这些治疗的成功率被使用到的程度没深入地被调查。谁的 682 个病人的医药记录 cryopreserved 精子房间由于癌症,治疗被分析。七十个这些病人在 20 年的经期(在在 cryopreservation 以后的开始的 4 年以内的大多数) 上为生育力治疗撤退了他们的冻结的精子。不同恶意的精子质量和为在与治疗的类型和恶意的类型的关系的怀孕成就的帮助繁殖治疗(艺术) 的结果被评估。结果证明在我们的单位为富饶治疗从癌症病人使用融化 cryo 的精子的率是 10.3 %。精子优秀索引在恶意的不同类型之间不同,与在阴囊的癌症测量的最差的质量。概念在 184 个艺术周期中的 46 个被完成(25 %) ,并且导致了 36 交货。注射(ICSI ) 方法论产出的 intracytoplasmic 精子的使用显著地更高的怀孕率(37.4 %) 比子宫内的授精(IUI;11.5 %) 并且类似于用这些形式的其它组不肥沃的夫妇。在 vitro,授精(IVF ) 没能生产怀孕。在结论,在癌症病人的 cryopresseved 精子的使用的率是相对低的(10.3 %) 。由 ICSI 的怀孕的成就介绍最好的选择但是当有足够的存储精子样品和足够的质量时, IUI 能被采用。Cryopreservation 是但为癌症病人保存未来生育力潜力和希望的最好的选择。 | Amnon Botchan Shiri Karpol Ofer Lehavi Gedalia Paz Sandra E Kleiman LeahYogev Haim Yavetz Ron Hauser | 2013 | Asian Journal of Andrology2013,15,3: | 4 |
| 10 | Clinical Presentation, Investigation, and Management of Pulmonary Vein Stenosis Complicating Ablation for Atrial Fibrillation显示文摘 | Douglas L. Packer Paul Keelan Thomas M. Munger Jerome F. Breen Sam Asirvatham Laura A. Peterson Kristi H. Monahan Mary F. Hauser K Chandrasekaran Lawrence J. Sinak David R. Holmes | 2005 | Circulation2005,,5: | 2 |
| 11 | Frequency and clinical determinants of dementia after ischemic stroke显示文摘 | D. W. Desmond J. T. Moroney M. C. Paik M. Sano J. P. Mohr S. Aboumatar C.-L. Tseng S. Chan J. B. W. Williams R. H. Remien W. A. Hauser Y. Stern | 2000 | Neurology2000,,5: | 2 |
| 12 | Ocrelizumab for primary progressive multiple sclerosis显示文摘 | Montalban X Hauser SL Kappos L | 2017 | 中华物理医学与康复杂志2017,39,3: | 2 |
| 13 | 中低收入国家癫痫过早死亡:国际抗癫痫联盟死亡率专业组系统评价显示文摘为了确定中低收入国家(Low-and middle-income countries,LMICs)癫痫相关的危险因素大小与过早死亡原因,专业组对来自LMICs(世界银行定义)的死亡率及癫痫相关文献报道进行系统检索,根据代表性,病例、诊断和死亡率的确证度对研究进行评估,并提取癫痫患者中的标准化死亡比(Standardized mortality ratios,SMR)和死亡率数据。研究调查了死亡的危险因素和原因。据估计,在高质量的群体研究中,癫痫患者年死亡率为19.8/1 000(9.7/1 000~45.1/1 000),加权中位SMR为2.6(1.3~7.2)。而临床队列研究显示的死亡率为7.1/1 000(1.6/1 000~25.1/1 000),加权中位SMR在男性中为5.0,女性中为4.5。在儿童和青少年、症状性癫痫或治疗依从性低的患者中发现了相对较高的SMR。群体研究显示,LMICs癫痫患者死亡的主要原因中直接归因于癫痫的平均比例死亡比(Proportional mortality ratio,PMR)为27.3%(5.0%~73.5%)。这些直接原因包括癫痫持续状态(报道的PMR为5.0%~56.5%)和癫痫猝死(Sudden unexpected death in epilepsy,SUDEP)(报道的PMR为1.0%~18.9%),与癫痫相关的间接死亡原因包括溺水、头部创伤和烧伤。LMICs癫痫患者的早亡率明显高于高收入国家。在LMICs,死亡率过高可能与患者难以获得医疗资源有关,例如发生癫痫持续状态时,以及包括溺水、头外伤和烧伤在内的可预防死因。这类过高的早亡率可以通过进行关于死亡风险的教育,提高治疗,包括抗癫痫药物治疗的可得性而大大降低。 | Levira F Thurman DJ Sander JW Hauser WA Hesdorffer DC Masanja H OdermattP Logroscino G Newton CR 陆璐 童馨 慕洁 | 2019 | 癫痫杂志2019,5,1: | 2 |
| 14 | Diatom-inspired Plastic Deformation Elements for Energy Absorption in Automobiles显示文摘 | Christin Hundertmark Rudiger Tinter Marc Ortelt Marcus J B Hauser | 2015 | Journal of Bionic Engineering2015,12,4: | 2 |
| 15 | Medications as a Potential Source of Exposure to Phthalates in the U.S. Population显示文摘 | Hernández-Díaz Sonia Mitchell Allen A Kelley Katherine E Calafat Antonia M Hauser Russ | 2009 | Environmental Health Perspectives2009,,2: | 2 |
| 16 | 中法海洋卫星及其典型应用显示文摘一、前言中法海洋卫星(CFOSAT)是我国航天领域第一次与先进宇航国家开展系统性、全流程合作的项目,也是中法两国在航天工程领域、海洋科学领域高水平合作的重要成果。2018年10月29日CFOSAT在我国甘肃酒泉卫星发射中心成功发射,2020年2月正式交付使用。 | 刘建强 蒋兴伟 郎姝燕 Daniele HAUSER 孙从容 徐莹 董晓龙 王丽丽 林文明 王久珂 刘金普 马小峰 | 2021 | 卫星应用2021,29,9: | 2 |
| 17 | 中法海洋卫星工程与应用显示文摘中法两国科学家首次提出了波谱仪、散射计联合探测同步获得海浪谱、海面风场的目标,研制了旋转扇形波束扫描散射计和六波束海浪波谱仪两个新型微波载荷,其性能达到同类载荷国际前列;首次在小卫星平台上实现了两台大功率Ku波段微波载荷,同时在轨全球长期工作;研发了小入射角海浪方向谱与高空间分辨率海面风场反演算法,形成海浪谱与海面风场产品体系;建立了两国联合以及星地一体化业务运行管理机制;中法海洋卫星风场产品在台风监测、南极科学考察航线保障中发挥重要作用;中法海洋卫星(CFOSAT)工程是中法两国在航天工程与海洋科学领域高水平合作的重要成果. | 刘建强 蒋兴伟 王丽丽 董晓龙 Daniele Hauser 林文明 孙从容 黄耀辉 Patrick Castillan 阎诚 翁春明 朱迪 徐莹 郎姝燕 刘金普 马小峰 丁振宇 | 2020 | 中国科技成果2020,,15: | 2 |
| 18 | Transplanted fetal striatum in Huntington's disease:phenotypic development and lack of pathology显示文摘 | Freeman TB Cicchettif Hauser RA | 2000 | Proc Natl Acad Sci USA2000,97,13: | 1 |
| 19 | The epidemiology of traumatic brain injury显示文摘 | Bruns J Jr Hauser WA | 2003 | Epilepsia2003,44,10: | 1 |
| 20 | The SABRE gene is required for normal cell expansion in Arabidopsis 显示文摘 | Aeschbacher R A Hauser M T Feldmann K A Benfey P N | 1995 | Genes& Development1995,9,3: | 1 |