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| 1 | 过瘤胃蛋氨酸、赖氨酸和组氨酸对泌乳奶牛生产性能的影响显示文摘试验旨在研究饲料中单独添加或综合添加过瘤胃(RP)蛋氨酸、赖氨酸和组氨酸及可代谢蛋白(MP)对泌乳后期奶牛生产性能的影响。试验选取72头荷斯坦奶牛,随机分为6组,试验期9周。奶牛随机分配到6个试验组中,2周作为1个变量周期:MPA组,根据美国国家科学研究委员会(2001)标准,在饲料中添加调节MP到243 g·d-1;MPD组,不添加MP,MP含量低于标准量54 g·d-1;MPDM组,在MPD组的基础上加入RP蛋氨酸;MPDL组,在MPD组的基础上加入RP赖氨酸;MPDH组,在MPD组的基础上加入组氨酸;MPDMLH组,在MPD组的基础上加入RP蛋氨酸、RP赖氨酸和RP组氨酸。试验结果表明,与MPA组对比,MPD组的干物质采食量(DMI)、产奶量、乳成分(乳脂肪、乳蛋白和乳糖)及能量校正的牛乳(ECM)、ECM饲料利用效率、牛奶和血浆中的N均降低。在MPD基础上补充RP赖氨酸可使乳蛋白率、血浆中葡萄糖浓度增加,且牛奶中N元素含量有增加的趋势;补充RP组氨酸可使DMI、牛奶浓缩蛋白增加,且乳脂肪、乳蛋白和ECM显著增加;补充3种RP氨基酸时,增加了乳蛋白率,使DMI和乳脂率有增加趋势,也提高了乳脂肪、乳蛋白含量和ECM及ECM饲料利用效率。与MPA相比,MPD组牛奶中N的含量有降低趋势,且血浆中必需氨基酸(除赖氨酸和蛋氨酸)浓度均降低。补充RP赖氨酸、RP蛋氨酸和RP组氨酸提高了血浆中蛋氨酸(除MPDM组)、赖氨酸和组氨酸浓度。饲喂MPD的奶牛血红蛋白浓度降低,血浆生长素含量高于MPA组。MPD组牛奶中总饱和脂肪酸浓度有高于MPA和MPDMLH组的趋势。MPD组的多元不饱和脂肪、牛奶中奇链与支链脂肪酸含量与MPA组相比,有降低趋势。试验结果表明,对于饲料中缺乏MP的奶牛,在饲料中添加组氨酸和添加3种RP氨基酸(赖氨酸、蛋氨酸和组氨酸)均有提高牛奶产量和牛奶组分含量的可能性。 | Giallongo F Harper M T Oh J Lopes J C Lapierre H Patton R A Parys C Shinzato I Hristov A N | 2016 | 饲料博览2016，0，7： | 4 |
| 2 | Peripheral interventions and antiplatelet therapy: Role in current practice显示文摘Peripheral arterial disease(PAD) is a common disorder associated with a high risk of cardiovascular mortality and continues to be under-recognized. The major risk factors for PAD are similar to those for coronary and cerebrovascular disease. Management includes exercise program, pharmacologic therapy and revascularization including endovascular and surgical approach. The optimal revascularization strategy, endovascular or surgical intervention, is often debated due to the paucity of head to head randomized controlled studies. Despite significant advances in endovascular interventions resulting in increased utilization over surgical bypass, significant challenges still remain. Platelet activation and aggregation after percutaneous transluminal angioplasty of atherosclerotic arteries are important risk factors for re-occlusion/restenosis and life-threatening thrombosis following endovascular procedures. Antiplatelet agents are commonly prescribed to reduce the risk of myocardial infarction, stroke and death from cardiovascular causes in patients with PAD. Despite an abundance of data demonstrating efficacy of antiplatelet therapy in coronary artery disease and cerebrovascular disease, there is a paucity of clinical information, clinical guidelines and randomized controlled studies in the PAD population. Hence, data on antiplatelet therapy in coronary interventions is frequently extrapolated to peripheral interventions. The aim of this review article is to elucidate the current data on revascularization and the role and duration of antiplatelet and anticoagulant therapy in re-vascularized lower limb PAD patients. | Pahul Singh Yenal Harper Carrie S Oliphant Mohamed Morsy Michelle Skelton Raza Askari Rami N Khouzam | 2017 | World Journal of Cardiology2017，9，7： | 2 |
| 3 | Early po~stoperative gastrointestinal activity显示文摘 | ROTHNIE N C HARPER R A K CATCHPOLE B N | 1963 | Lancet1963，2，： | 1 |
| 4 | Life-history concepts andthepopulation biology of clonal organisms 显示文摘 | Saekvilh Hamilton N R Schmid B Harper J L | 1987 | Proceeding of Royal Society London B1987，232，： | 1 |
| 5 | Effect of capture and season on fecal glucocorticoid levels in dee mice(Peromyscus maniculatus) and red-backed voles (Clethrionomys gapperi)显示文摘 | Harper J M Austad S N | 2001 | General and Comparative Endocrinology2001，123，3： | 1 |
| 6 | The p21CDK-interacting protein Gip1 is a potent inhibitor of G1cyclin-dependent kinases显示文摘 | Adami G R Wei N | 1993 | Cell1993，75，： | 1 |
| 7 | The p21 Cdk interacting proteinCipl is a potent inhibitor of G1 cyclin dependent kinases 显示文摘 | Harper JW Adami GR Wei N | 1993 | Cell1993，75，： | 1 |
| 8 | Understanding Organic Processes in ionic liquids:achievements so far and challenges remaining显示文摘 | Harper J B Kobrak M N | 2006 | Mini-Rev Org Chem2006，3，3： | 1 |
| 9 | Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-kappa B activation by inhibition of apical caspases显示文摘 | HarPer N Farrow SN KaPtein A | 2001 | J Biol Chem2001，276，34： | 1 |
| 10 | Curtin industrial safety trial:Managerial behavior and program effectiveness 显示文摘 | Harper A C Cordery J L De Klerk N H Sevastos P Geelhoed E Gunson C Robinson L Sutherland M Osbom D Colquhoun J | 1996 | Safety Science1996，24，3： | 1 |
| 11 | The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease显示文摘 | Packer A N Xing Y Harper S Q | 2008 | J Neurosci2008，28，14： | 1 |
| 12 | The p21cdk interacting protein Cipl is a potent inhibitor of G1 cyclin-depedent kinase显示文摘 | Harper JW AdamiGR Wei N | 1993 | Cell1993，75，4： | 1 |
| 13 | Interference in dune annual: spatial pattern and neighborhood effects显示文摘 | Mack R N Harper J L | 1977 | J Ecol1977，65，2： | 1 |
| 14 | Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia显示文摘 | MacFarlane M Harper N Snowden R T etal | 2002 | Oncogene2002，21，68： | 1 |
| 15 | Characterization of the inhibition of K+ absorption in oats roots by salicylic acid显示文摘 | Harper J R Balke N E | 1981 | Plant Physiol1981，68，： | 1 |
| 16 | MAPKs:new targets for neurodegeneration显示文摘 | Harper S J Wilkie N | 2003 | Expert Opin Ther Targets2003，7，2： | 1 |
| 17 | CDK2 encodes a 33-ku cyclinA-associated protein kinase and is expressed before CDC2 in the cell cycle 显示文摘 | BIOL N HARPER J W | 1992 | Proc Natl Acad Sci USA1992，89，： | 1 |
| 18 | Family-based cardiac screening in relatives of victims of sudden arrhythmic death syndrome 显示文摘 | McGorrian C Constant O Harper N | 2013 | Europace2013，15，7： | 1 |
| 19 | Effect of glycine and serine on methionine metabolism in rat fed diets high in methionine显示文摘 | Benevenga N K Harper A E | 1970 | J Nutr1970，100，： | 1 |
| 20 | The p21 Cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases显示文摘 | Harper J W Adami G R Wei N | 1993 | Cell1993，75，4： | 1 |
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