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| 1 | Tectonic evolution of the Western Kunlun orogenic belt in northern Qinghai-Tibet Plateau:Evidence from zircon SHRIMP and LA-ICP-MS U-Pb geochronology显示文摘The Western Kunlun Range in northern Qinghai-Tibet Plateau is composed of the North Kunlun Terrane,the South Kunlun Terrane and the Karakorum-Tianshuihai Terrane. Here we report zircon SHRIMP and LA-ICP-MS U-Pb ages of some metamorphic and igneous rocks and field observations in order to pro-vide a better understanding of their Precambrian and Palaeozoic-early Mesozoic tectonic evolution. Based on these data we draw the following conclusions: (1) The paragneisses in the North Kunlun Terrane are likely of late Mesoproterozoic age rather than Palaeoproterozoic age as previously thought,representing tectonothermal episodes at 1.0―0.9 Ga and ~0.8 Ga. (2) The North Kunlun Terrane was an orogenic belt accreted to the southern margin of Tarim during late Mesoproterozoic to early Neopro-terozoic,the two episodes of metamorphisms correspond to the assemblage and breakup of Rodinia respectively. (3) The Bulunkuole Group in western South Kunlun Terrane,which was considered to be the Palaeoproterozoic basement of the South Kunlun Terrane by previous studies,is now subdivided into the late Neoproterzoic to early Palaeozoic paragneisses (khondalite) and the early Mesozoic metamorphic volcano-sedimentary series; the paragneisses were thrust onto the metamorphic vol-cano-sedimentary series from south to north,with two main teconothermal episodes (i.e.,Caledonian,460―400 Ma,and Hercynian-Indosinian,340―200 Ma),and have been documented by zircon U-Pb ages. (4) In the eastern part of the South Kunlun Terrane,a gneissic granodiorite pluton,which intruded the khondalite,was crystallized at ca. 505 Ma and metamorphosed at ca. 240 Ma. In combination with geochronology data of the paragneiss,we suggest that the South Kunlun Terrane was a Caledonian accretionary orogenic belt and overprinted by late Paleozoic to early Mesozoic arc magmatism. | ZHANG ChuanLin LU SongNian YU HaiFeng YE HaiMin | 2007 | Science China Earth Sciences2007，50，6： | 45 |
| 2 | Surgical outcomes of mini-open Wiltse approach and conventional open approach in patients with single-segment thoracolumbar fractures without neurologic injury显示文摘This study aimed to introduce a novel mini-open pedicle screw fixation technique via Wiltse approach,and compared it with the traditional posterior open method.A total of 72 cases of single-segment thoracolumbar fractures without neurologic injury underwent pedicle screw fixation via two different approaches.Among them,37 patients were treated using posterior open surgery,and 35 patients received mini-open operation via Wiltse approach.Crew placement accuracy rate,operative time,blood loss,postoperative drainage,postoperative hospitalization time,radiation exposure time,postoperative improvement in R value,Cobb's angle and visual analog scale(VAS)scores of the two methods were compared.There were no significant differences in the accuracy rate of pedicle screw placement,radiation exposure and postoperative R value and Cobb's angle improvement between the two groups.However,the mini-open method had obvious advantages over the conventional open method in operative time,blood loss,postoperative drainage,postoperative hospitalization time,and postoperative improvement in VAS.The mini-open pedicle screw technique could be applied in treatment of single-segment thoracolumbar fracture without neurologic injury and had advantages of less tissue trauma,short operative and rehabilitative time on the premise of guaranteed accuracy rate and no increased radiation exposure. | Haijun Li Lei Yang Hao Xie Lipeng Yu Haifeng Wei Xiaojian Cao | 2015 | The Journal of Biomedical Research2015，29，1： | 43 |
| 3 | Millennial temperature reconstruction based on tree-ring widths of Qilian juniper from Wulan,Qinghai Province,China显示文摘The climate of the past 1000 years is an important context for evaluating the recent climate warming.However,there are few 1000-year-long climate reconstructions with annual resolution in the Qing-hai-Tibet Plateau.In this paper,a dendroclimatic analysis was conducted for the radial growth of Qilian juniper from the upper forest limit in Wulan,Qinghai Province.The results of correlation analysis between the tree-ring widths and the climate variables indicate that the growth of junipers at the upper forest limit is mainly limited by low temperatures of September,November and February of the pregrowth season,and July of the current growth season.There is no significant correlation between the tree-ring widths and precipitation.A mean temperature from the previous year's September to the current year's April was reconstructed for the Wulan area since A.D.1000.The reconstruction can explain 40.8% of the instrumental variance in the calibration period(1856―2002).The reconstruction shows that the 20th century is the warmest 100 years,and the 1990s is the warmest decade during the past 1000 years,while the coldest 100 years and decade occur at 1600―1699 and 1642―1651,respectively.The variations are verified well by the temperature reconstruction of the middle Qilian Mountain(QL) and the total organic carbon(TOC) in the Qinghai Lake sediments.The comparison of our reconstruction with the annual temperature reconstruction of extra-tropical Northern Hemisphere suggests that the climate of Wulan during the Medieval Warm Period is of obvious regional specialty,but there was a good response to the climate of hemispheric scales during the recent 400 years. | ZHU HaiFeng ZHENG YongHong SHAO XueMei LIU XiaoHong XU Yan LIANG ErYuan | 2008 | Chinese Science Bulletin2008，53，24： | 40 |
| 4 | One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system显示文摘 | Haifeng Wan Chunjing Feng Fei Teng Shihua Yang Baoyang Hu Yuyu Niu Andy Peng Xiang Weizhen Fang Weizhi Ji Wei Li Xiaoyang Zhao Qi Zhou | 2015 | Cell Research2015，25，2： | 39 |
| 5 | One-step high-efficiency CRISPR/Cas9-mediated genome editing in Streptomyces显示文摘编辑技术 CRISPR 的指导 RNA 的 DNA 定期聚类 interspaced 短 palindromic repeats/Cas9 被用来介绍双 stranded 闯入染色体并且在细菌指导随后的地点特定的插入 / 删除或基因材料的代替例如 Escherichia coli,链球菌肺病,和乳杆菌 reuteri。在这研究,我们建立了在 Streptomyces 基因操作为使用编辑 plasmid pKCcas9dO 的一个高效率的 CRISPR/Cas9 染色体,它包括目标特定的指南 RNA,优化 codon 的 cas9,和二个指导相同的修理模板。由交付编辑 plasmids 进模型紧张 Streptomyces coelicolor M145 的 pKCcas9dO 系列,通过一步舞 intergeneric 转移,我们完成了与60%100%的高效率在不同层次编辑的染色体,包括单个基因删除,例如 actII-orf4 ,整顿,和 glnR ,并且单个大尺寸的基因簇删除,扮演 21.3 kb , undecylprodigiosin 红 31.6 kb ,和 Ca 2+-dependent 抗菌素例如 actinorhodin 的抗菌素 biosynthetic 簇 82.8 kb 。而且,我们也分别地与 54% 和 45% 的高效率认识到 actII-orf4 和整顿,并且 ACT 和红 biosynthetic 基因簇的同时的删除。最后,我们使用了这个系统介绍核苷酸点变化进 rpsL 基因,它与抵抗授与异种到链球菌。用这个系统,显著地,为一个轮染色体修正要求的时间被三分之一个减少或为常规方法的那些的一个一半。这些结果清楚地显示实质地编辑系统的确定的 CRISPR/Cas9 染色体改进与当前存在的方法相比编辑效率在的染色体 Streptomyces,和它在另外的放线菌种类为申请有诺言到染色体修正。 | He Huang Guosong Zheng Weihong Jiang Haifeng Hu Yinhua Lu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，4： | 37 |
| 6 | Widespread Whole Genome Duplications Contribute to Genome Complexity and Species Diversity in Angiosperms显示文摘基因复制为产生新奇功能提供进化潜力,当 polyploidization 或整个染色体复制(WGD ) 开始加倍染色体并且导致百~千个保留的副本时。WGD 被通常在优核质的许多充满种类的系发现的证据强烈支持,并且因此在种类多样化被看作一个主要驱动力。我们执行了 59 公共 genomes/transcriptomes 和盖住被子植物的主要的系的 46 最新定序的 transcriptomes 的比较 genomic 和 phylogenomic 分析 ? 由调查几万个基因家谱检测大规模基因复制事件。这些分析证实了大多数以前报导的 WGD 并且在许多系为新奇的提供了充分证据。检测 WGD 与约 2160 万年的估计的半衰期在进化期间支持了指数的基因损失的一个模型,并且与两个被相关有多样化的高度和全球气候的时期的系的出现变化。新数据集和分析 ? 检测了广泛地在支持被子植物放射并且提高他们的改编到环境变化为 WGD 的角色在被子植物进化,在必要细胞的新陈代谢的基因功能的揭开的优先的保留,和提供的线索期间散布的许多新奇 WGD。 | Ren Ren Haifeng Wang Chunce Guo Ning Zhang Liping Zeng Yamao Chen Hong Ma Ji Qi | 2018 | Molecular Plant2018，11，3： | 35 |
| 7 | Impact of Grid Connection of Large-Scale Wind Farms on Power System Small-Signal Angular Stability显示文摘The grid connection of a large-scale wind farm could change the load flow/configuration of a power system and introduce dynamic interactions with the synchronous generators(SGs),thus affecting system small-signal angular stability.This paper proposes an approach for the separate examination of the impact of those affecting factors,i.e.,the change of load flow/configuration and dynamic interactions brought about by the grid connection of the wind farm,on power system smallsignal angular stability.Both cases of grid connection of the wind farm,either displacing synchronous generators or being directly added into the power system,are considered.By using the proposed approach,how much the effect of the change of load flow/configuration brought about by the wind farm can be examined,while the degree of impact of the dynamic interaction of the wind farm with the SGs can be investigated separately.Thus,a clearer picture and better understanding of the power system small-signal angular stability as affected by grid connection of the large-scale wind farm can be achieved.An example of the power system with grid connection of a wind farm is presented to demonstrate the proposed approach. | Wenjuan Du Jingtian Bi Tong Wang Haifeng Wang | 2015 | CSEE Journal of Power and Energy Systems2015，1，2： | 39 |
| 8 | The AGL6-like gene OsMADS6 regulates floral organ and meristem identities in rice显示文摘Although AGAMOUS-LIKE6 (AGL6) MADS-box genes are ancient with wide distributions in gymnosperms and angiosperms, their functions remain poorly understood. Here, we show the biological role of the AGL6-1ike gene, OsMADS6, in specifying floral organ and meristem identities in rice (Oryza sativa L.). OsMADS6 was strongly ex- pressed in the floral meristem at early stages. Subsequently, OsMADS6 transcripts were mainly detectable in paleas, lodicules, carpels and the integument of ovule, as well as in the receptacle. Compared to wild type plants, osmads6 mutants displayed altered palea identity, extra glume-like or mosaic organs, abnormal carpel development and loss of floral meristem determinacy. Strikingly, mutation of a SEPALLATA (SEP)-like gene, OsMADS1 (LHS1), enhanced the defect of osmads6 flowers, and no inner floral organs or glume-like structures were observed in whorls 2 and 3 of osmadsl-z osmads6-1 flowers. Furthermore, the osmadsl-z osmads6-1 double mutants developed severely indetermi- nate floral meristems. Our finding, therefore, suggests that the ancient OsMADS6 gene is able to specify 'floral state' by determining floral organ and meristem identities in monocot crop rice together with OsMADS1. | Haifeng Li Wanqi Liang Ruidong Jia Changsong Yin Jie Zong Hongzhi Kong Dabing Zhang | 2010 | Cell Research2010，20，3： | 33 |
| 9 | Cu–Mn–Ce ternary mixed-oxide catalysts for catalytic combustion of toluene显示文摘Cu–Mn, Cu–Mn–Ce, and Cu–Ce mixed-oxide catalysts were prepared by a citric acid sol–gel method and then characterized by XRD, BET, H_2-TPR and XPS analyses. Their catalytic properties were investigated in the toluene combustion reaction. Results showed that the Cu–Mn–Ce ternary mixed-oxide catalyst with 1:2:4 mole ratios had the highest catalytic activity, and 99% toluene conversion was achieved at temperatures below 220°C. In the Cu–Mn–Ce catalyst, a portion of Cu and Mn species entered into the Ce O_2 fluorite lattice, which led to the formation of a ceria-based solid solution. Excess Cu and Mn oxides existed on the surface of the ceria-based solid solution. The coexistence of Cu–Mn mixed oxides and the ceria-based solid solution resulted in a better synergetic interaction than the Cu–Mn and Cu–Ce catalysts, which promoted catalyst reducibility, increased oxygen mobility, and enhanced the formation of abundant active oxygen species. | Hanfeng Lu Xianxian Kong Haifeng Huang Ying Zhou Yinfei Chen | 2015 | Journal of Environmental Sciences2015，27，6： | 31 |
| 10 | Distribution and assessment of heavy metals in the surface sediment of Yellow River, China显示文摘Large amounts of heavy metals discharged by industrial cities that are located along the middle reach of Yellow River, China have detrimental impacts on both the ecological environment and human health. In this study, fourteen surface sediment samples were taken in the middle reach of the Yellow River. Contents of Zn, Pb, Ni, Cu, Cr, Cd, As were measured, and the pollution status was assessed using three widely used pollution assessment methods, including the single factor index method, Nemerow pollution index method and potential ecological risk index. The concentrations of the studied heavy metals followed the order: Zn > Cr > Cu > Ni > Pb > As > Cd. Nearly 50% of sites had Cu and Cr accumulation. The concentration of Cu at the Yiluo River exceeded the secondary standard value of the Environmental quality standard for soils. Comparison of heavy metal concentrations between this study and other selected rivers indicated that Cu and Cr may be the major pollutants in our case. The single factor index indicated that many samples were at high levels of pollution for Cu and Cd; the Nemerow pollution index indicated that the Yihe River, Luohe River, Yiluo River and Huayuankou were polluted. According to the results of potential ecological risk assessment, Cd in the tributaries of Luo River, Yihe River,and Yiluo River showed high risk toward the ecosystem and human health, Cd in Huanyuankou and Cu in Yiluo River showed a middle level of risk and other samples were at a low level of risk. | Nan Yan Wenbin Liu Huiting Xie Lirong Gao Ying Han Mengjing Wang Haifeng Li | 2016 | Journal of Environmental Sciences2016，28，1： | 33 |
| 11 | Modeling on Heat and Mass Transfer in Stored Wheat during Forced Cooling Ventilation显示文摘A mathematical model based on the theory of heat and mass transfer in porous media was developed to simulate the evolution of grain temperature and moisture content in a wheat storage bin during ventilation with cooling air at the constant temperature and humidity.Unlike the previous works on this aspect,the present work was not focused on cooling the stored grain by ventilation with ambient air,but with the refrigerated air.Validation was performed by comparing between predicted and measured grain temperature and grain moisture content for two cases.Predicted data were in reasonable good agreement with measured ones.The model and the parameter values used in the model are applicable for predicting temperature and moisture of stored grains under ventilation conditions. | Yuancheng WANG,Haifeng DUAN,Hao ZHANG and Zhaohong FANG College of Thermal Energy Engineering,Shandong Jianzhu University,Jinan 250101,China | 2010 | Journal of Thermal Science2010，19，2： | 27 |
| 12 | Atg7 is required for acrosome biogenesis during spermatogenesis in mice显示文摘acrosome 是盖住精子原子核的前面的部分并且在授精的过程起一个必要作用的一个专业化细胞器。位于这个 lysosome 相关的细胞器(LRO ) 的生物的续生说下面的分子的机制大部分仍然是未知的。这里,我们显示出房间特定的 Atg7 大美人老鼠是的那个细菌由于在 acrosome 生物的续生说的一个缺点不肥沃并且显示了类似于人的 globozoospermia 的显型;这个繁殖缺点被 intracytoplasmic 精子注射成功地救。而且,在细菌房间的 Atg7 的弄空没影响细菌房间的开发的早阶段,但是精子发生在以后上演,在 Golgi 期间没有通过到保险丝进一个单个 acrosomal 泡的 proacrosomal 泡分阶段执行,它最后导致了不规则或将近 round-headed 精子。Autophagic 流动在弄空 Atg7 的细菌房间被破坏,最后导致 LC3 变化形式的失败到 Golgi 导出仪器的泡。另外, Atg7 部分调整了另一 globozoospermia 相关的蛋白质,联系 Golgi 的 PDZ 卷和卷卷包含主题的蛋白质(GOPC ) ,在 acrosome 生物的续生说期间。最后,任何一个 autophagy 的注射或进睾丸的 lysosome 禁止者导致了类似的显型到细菌的房间特定的 Atg7 大美人老鼠。总的来说,我们的结果揭开为在 acrosome 的生物的续生说的 Atg7 的一个新角色,并且我们提供证据为 acrosome 支持 autolysosome 起源假设。 | Hongna Wang Haifeng Wan Xixia Li Weixiao Liu Qi Chen Yaqing Wang Lin Yang Hongmei Tang Xiujun Zhang Enkui Duan Xiaoyang Zhao Fei Gao Wei Li | 2014 | Cell Research2014，24，7： | 25 |
| 13 | Immune secondary response and clonal selection inspired optimizers显示文摘The immune system's ability to adapt its B cells to new types of antigen is powered by processes known as clonal selection and affinity maturation. When the body is exposed to the same antigen,immune system usually calls for a more rapid and larger response to the antigen,where B cells have the function of negative adjustment. Based on the clonal selection theory and the dynamic process of immune response,two novel artificial immune system algorithms,secondary response clonal programming algorithm (SRCPA) and secondary response clonal multi-objective algorithm (SRCMOA),are presented for solving single and multi-objective optimization problems,respectively. Clonal selection operator (CSO) and secondary response operator (SRO) are the main operators of SRCPA and SRCMOA. Inspired by the clonal selection theory,CSO reproduces individuals and selects their improved maturated progenies after the affinity mat-uration process. SRO copies certain antibodies to a secondary pool,whose members do not participate in CSO,but these antibodies could be activated by some external stimulations. The update of the secondary pool pays more attention to maintain the population diversity. On the one hand,decimal-string representation makes SRCPA more suitable for solving high-dimensional function optimiza-tion problems. Special mutation and recombination methods are adopted in SRCPA to simulate the somatic mutation and receptor edit-ing process. Compared with some existing evolutionary algorithms,such as OGA/Q,IEA,IMCPA,BGA and AEA,SRCPA is shown to be able to solve complex optimization problems,such as high-dimensional function optimizations,with better performance. On the other hand,SRCMOA combines the Pareto-strength based fitness assignment strategy,CSO and SRO to solve multi-objective optimization problems. The performance comparison between SRCMOA,NSGA-Ⅱ,SPEA,and PAES based on eight well-known test problems shows that SRCMOA has better performance in converging to approximate Pareto-optimal fronts with wide distributions. | Maoguo Gong Licheng Jiao Lining Zhang Haifeng Du | 2009 | Progress in Natural Science:Materials International2009，19，2： | 24 |
| 14 | Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails显示文摘 | Yanbin Fu Chenwen Huang Xinxiu Xu Haifeng Gu Youqiong Ye Cizhong Jiang Zilong Qiu Xin Xie | 2015 | Cell Research2015，25，9： | 24 |
| 15 | Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells显示文摘体的房间能由定义因素是进导致的 pluripotent 干细胞(iPSCs ) 的 reprogrammed。reprogramming 的低效率和 oncogenes 和病毒的向量的 genomic 集成限制了 iPSCs 的潜在的申请。这里,我们报导那锂(李) ,药过去常对待心情混乱,极大地从老鼠提高 iPSC 产生胚胎的成纤维细胞和人的脐的静脉 endothelial 房间。李与(Oct4 ) 或二个因素(OS 或好) 便于 iPSC 产生。支持 reprogramming 上的李的效果仅仅部分取决于它的主要目标 GSK3β。不同于另外的 GSK3β禁止者,李不仅增加 Nanog 的表示,而且提高 Nanog 的 transcriptional 活动。我们也发现李由经由 LSD1 的 downregulation 支持 epigenetic 修正施加它的效果, H3K4 特定的 histone demethylase。将 LSD1 击倒部分在提高 reprogramming 模仿李的效果。我们的结果不仅提供一个直接方法改进 iPSC 产生效率,而且为体的房间 reprogramming 作为一个批评调节的人识别了 histone demethylase。 | Quan Wang Xinxiu Xu Jun Li Jing Liu Haifeng Gu Ru Zhang Jiekai Chen Yin Kuang Jian Fei Cong Jiang Ping Wang Duanqing Pei Sheng Ding Xin Xie | 2011 | Cell Research2011，21，10： | 23 |
| 16 | Nitrogen removal and simultaneous nitrification and denitrification in a fluidized bed step-feed process显示文摘For urban wastewater treatment,we conducted a novel four-stage step-feed wastewater treatment system combined with a fluidized bed laboratory experiment to investigate chemical oxygen demand(COD),NH4+-N,and total nitrogen(TN) removal performance.The removal rates of COD,NH4+-N and TN were 88.2%,95.7%,and 86.4% with e?uent concentrations of COD,NH4+-N and TN less than 50,8,and 10 mg/L,respectively.Biomass and bacterial activities were also measured,with results showing more nitrobacteria in the activated sludge than in the biofilm;however,bacterial activity of the biofilm biomass and the activated sludge were similar.Nitrogen concentrations during the process were also detected,with simultaneous nitrification and denitrification found to be obvious. | BingWang Wei Wang Hongjun Han Hongbo Hu Haifeng Zhuang | 2012 | Journal of Environmental Sciences2012，24，2： | 22 |
| 17 | Optimal approximation of linear systems by artificial immune response显示文摘This paper puts forward a novel artificial immune response algorithm for op-timal approximation of linear systems. A quaternion model of artificial immune response is proposed for engineering computing. The model abstracts four elements, namely, antigen, antibody, reaction rules among antibodies, and driving algorithm describing how the rules are applied to antibodies, to simulate the process of immune response. Some reaction rules including clonal selection rules, immunological memory rules and immune regulation rules are introduced. Using the theorem of Markov chain, it is proofed that the new model is convergent. The experimental study on the optimal approximation of a stable linear system and an unstable one show that the approximate models searched by the new model have better performance indices than those obtained by some existing algorithms including the differential evolution algorithm and the multi-agent genetic algorithm. | GONG Maoguo DU Haifeng JIAO Licheng | 2006 | Science in China(Series F)2006，49，1： | 21 |
| 18 | Radix Astragali-induced differentiation of rat bone marrow-derived mesenchymal stem cells显示文摘BACKGROUND:Chemical induction has been shown to be effective at promoting the differentiation of bone marrow-derived mesenchymal stem cells(MSCs).However,these inductors have cytotoxicity side effects that may damage cells over time.Traditional Chinese medicines avoid this disadvantage while still producing effective induction. OBJECTIVE:To investigate the influence of Radix Astragali(Huangqi) on the differentiation of MSCs. DESIGN,TIME AND SETTING:In vitro study of traditional Chinese medicine in neural stem cell differentiation.The experiment was performed at the Central Laboratory of Hebei North University between April and June 2007. MATERIALS:Radix Astragali solution(lot No.060105;license No.Z53021585) was purchased from Dali Pharmaceutical Co.,Ltd.,China;rabbit anti-rat nestin,rabbit anti-rat neuron-specific enolase (NSE),mouse anti-rat microtubule-associated protein 2,and rabbit anti-rat glial fibrillary acidic protein were purchased from Wuhan Boster,China. METHODS:Whole bone marrow was isolated from the femur and tibia of 6-week-old male Wistar rats and subcultured.The fourth passage of MSCs were harvested and induced by different concentrations(50,100,200,400 g/L) of Radix Astragali. MAIN OUTCOME MEASURES:Hematoxylin-eosin staining was used to observe MSC morphology after 24 hours of induction.Immunocytochemistry was employed to observe the expression of NSE (specific neuronal marker),nestin(marker of neural stem cell),glial fibrillary acidic protein and microtubule-associated protein 2(markers of astrocytes). RESULTS:Following Radix Astragalitreatment,changes occurred in cell morphology including:cell body pyknosis;thin and long processes formed in some cells,with growth corresponding to drug concentration and induction time;and the formation of network-like connections between some cells. With increasing drug concentration and induction time,nestin expression was upregulated,and the number of positive cells increased;cells produced NSE,glial fibrillary acidic protein and microtubule-associated protein 2;nestin was expressed earlier than glial fibrillary acidic protein and microtubule-associated protein 2 expression.In addition,the number of NSE-positive cells was increased significantly more than glial fibrillary acidic protein-positive cells. CONCLUSION:Radix Astragali promoted process formation in stem cells.It may induce the differentiation of MSCs into neural stem cells,and subsequently into neuronal-and glial-like cells. Radix Astragali exhibits stronger inductive effect on neuronal differentiation than glial differentiation of MSCs. | Xinsheng Wang Haifeng Li Ying Zhao Xiaoli Zhang Aihua Bo | 2009 | Neural Regeneration Research2009，4，7： | 21 |
| 19 | Decision Tree Based Online Stability Assessment Scheme for Power Systems with Renewable Generations显示文摘The stochastic fluctuation of renewable energy resources has significant impact on the stability of the power system with renewable generations and results in change in stability.Therefore,it is necessary to track the changing stability of the power system with renewable generations,a task that can be performed online.This paper details the use of decision trees to predict multi-mode damping of power system integrating renewable generations with the help of wide-area measurements system(WAMS).Power systems with renewable source generation are complex with vast amounts of data being collected from WAMS.Decision trees(DTs)are employed as a means to handle vast quantities of wide-area information,which involves the mode damping information indicating the stability.A 16-generator,68-bus system with photovoltaic power generation and wind power generation is used as the test system.Remote signals obtained from phasor measurement units(PMUs)are employed as the input variables of DTs for predicting purposes.The simulation results demonstrate that the proposed predicting scheme is able to suggest the optimal course of action to remedy any near instability or unstable electromechanical oscillations even without prior knowledge of the varying output of the renewable source power. | Tong Wang Tianshu Bi Haifeng Wang Jizhen Liu | 2015 | CSEE Journal of Power and Energy Systems2015，1，2： | 21 |
| 20 | Formation and destruction processes of upper Sinian oil-gas pools in the Dingshan-Lintanchang structural belt, southeast Sichuan Basin, China显示文摘The lower Cambrian Niutitang Formation hydrocarbon source rocks at the Dingshan-Lintanchang structure in the southeast Sichuan Basin were of medium-good quality with two excellent hydrocarbon-generating centers developed in the periphery areas, with a possibility of forming a medium to large-sized oil-gas field. Good reservoir rocks were the upper Sinian (Dengying Formation) dolomites. The mudstone in the lower Cambrian Niutitang Formation with a good sealing capacity was the cap rock. The widely occurring bitumen in the Dengying Formation indicates that a paleo oil pool was once formed in the study area. The first stage of paleo oil pool formation was maturation of the lower Cambrian source rocks during the late Ordovician. Hydrocarbon generation from the lower Cambrian source rocks stopped due to the Devonian-Carboniferous uplifting. The lower Cambrian source rocks then restarted generation of large quantities of hydrocarbons after deposition of the middle Permian sediments. This was the second stage of the paleo oil pool formation. The oil in the paleo oil pool began to crack during the late Triassic and a paleo gas pool was formed. This paleo gas pool was destroyed during the Yanshan-Himalayan folding, uplifting and denudation. Bitumen can be widely seen in the Dengying Formation in wells and outcrops in the Sichuan Basin and its periphery areas. This provides strong evidence that the Dengying Formation in the Sichuan Basin and its periphery areas was once an ultra-large structural-lithologic oil-gas field, which was damaged during the Yanshan-Himalayan period. | Liu Shugen Zhang Zhijing Huang Wenming Wang Guozhi Sun Wei Xu Guosheng Yuan Haifeng Zhang Changjun Deng Bin | 2010 | Petroleum Science2010，7，3： | 20 |
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