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| 1 | Review of 500 single incision laparoscopic colorectalsurgery cases-Lessons learned显示文摘Single incision laparoscopic surgery(SILS) is a minimally invasive platform with specific benefits over traditional multiport laparoscopic surgery. The safety and feasibility of SILS has been proven, and the applications continue to grow with experience. After 500 cases at a high-volume, single-institution, we were able to standardize instrumentation and operative steps, as well as develop adaptations in technique to help overcome technical and ergonomic challenges. These technical adaptations have allowed the successful application of SILS to technically difficult patient populations, such as pelvic cases, inflammatory bowel disease cases, and high body mass index patients. This review is a frame of reference for the application and wider integration of the single incision laparoscopic platform in colorectal surgery. | Deborah S Keller Juan R Flores-Gonzalez Sergio Ibarra Eric M Haas | 2016 | World Journal of Gastroenterology2016，22，2： | 8 |
| 2 | Review of single incision laparoscopic surgery in colorectal surgery显示文摘As surgical techniques continue to move towards less invasive techniques,single incision laparoscopic surgery(SILS),a hybrid between traditional multiport laparoscopy and natural orifice transluminal endoscopic surgery,was introduced to further the enhanced outcomes of multiport laparoscopy. The safety and feasibility of SILS for both benign and malignant colorectal disease has been proven. SILS provides the potential for improved cosmesis,postoperative pain,recovery time,and quality of life at the drawback of higher technical skill required. In this article,we review the history,describe the available technology and techniques,and evaluate the benefits and limitations of SILS for colorectal surgery in the published literature. | Nisreen Madhoun Deborah S Keller Eric M Haas | 2015 | World Journal of Gastroenterology2015，21，38： | 8 |
| 3 | Enhanced expression of interleukin-18 in serum and pancreas of patients with chronic pancreatitis显示文摘AIM: To investigate interleukin-18 (IL-18) in patients with chronic panreatitis (CP). METHODS: We studied 29 patients with CP and 30 healthy controls. Peripheral blood mononuclear cells (PBMC) were isolated and incubated with 50 mmol/L ethanol, lipopolysaccharide (LPS) (doses 25 g/L, 250 g/L, 2500 g/L) and both agents for 24 h. Levels of IL-18 in the supernatants, and levels of IL-18, IL-12, interferon (IFN)-γ and soluble CD14 in the serum were analysed by ELISA technique. Expression of IL-18 in PBMC was investigated by reverse-transcription (RT)-PCR. IL-18 protein levels in CP tissue and in normal pancreas were studied by ELISA technique. IL-18 levels in PBMC and pancreatic tissue were determined by Westernblot. Im-munohistochemistry for pancreatic IL-18 expression was performed. RESULTS: In patients, IL-18 serum levels were signifi-cantly enhanced by 76% (mean: 289.9 ± 167.7 ng/L) compared with controls (mean: 165.2 ± 43.6 ng/L; P < 0.0005). IL-12 levels were enhanced by 25% in patients (18.3 ± 7.3 ng/L) compared with controls (14.7 ± 6.8ng/L, P = 0.0576) although not reaching the statistical significance. IFN-γ and soluble CD14 levels were not in-creased. In vitro, LPS stimulated significantly and dose-dependently IL-18 secretion from PBMC. Incubation with ethanol reduced LPS-stimulated IL-18 secretion by about 50%. The mRNA expression of IL-18 in PBMC and the response of PBMC to ethanol and LPS was similar in CP patients and controls. In PBMC, no significant differences in IL-18 protein levels were detected between patients and controls. IL-18 protein levels were increased in CP tissues compared to normal pancreatic tissues. IL-18 was expressed by pancreatic acinar cells and by infiltrating inflammatory cells within the pancreas. CONCLUSION: IL-18 originates from the chronically inflammed pancreas and appears to be involved in the fibrotic destruction of the organ. | Alexander Schneider Stephan L Haas Ralf Hildenbrand Sren Siegmund Iris Reinhard Helmut Nakovics Manfred V Singer Peter Feick | 2006 | World Journal of Gastroenterology2006，12，40： | 4 |
| 4 | Endoscopic retrograde cholangiopancreatography guided interventions in the management of pancreatic cancer显示文摘Pancreatic cancer is the leading cause of cancer-related morbidity and mortality with an overall five-year survival of less than 9%in the United States.At presentation,the majority of patients have painless jaundice,pruritis,and malaise,a triad that develops secondary to obstruction,which often occurs late in the course of the disease process.The technical advancements in radiological imaging and endoscopic interventions have played a crucial role in the diagnosis,staging,and management of patients with pancreatic cancer.Endoscopic retrograde cholangiopancreatography(ERCP)-guided diagnosis(with brush cytology,serial pancreatic juice aspiration cytologic examination technique,or biliary biopsy)and therapeutic interventions such as pancreatobiliary decompression,intraductal and relief of gastric outlet obstruction play a pivotal role in the management of advanced pancreatic cancer and are increasingly used due to improved morbidity and complication rates compared to surgical management.In this review,we highlight various ERCP-guided diagnostic and therapeutic interventions for the management of pancreatic cancer. | Muhammad Nadeem Yousaf Hamid Ehsan Ahsan Wahab Ahmad Muneeb Fizah S Chaudhary Richard Williams Christopher J Haas | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，10： | 3 |
| 5 | Morphology‐function relationships and repeatability in the sperm of Passer sparrows显示文摘 | Emily R.A. Cramer Terje Laskemoen Even Stensrud Melissah Rowe Fredrik Haas Jan T. Lifjeld Glenn‐Peter S?tre Arild Johnsen | 2015 | Journal of Morphology2015，，： | 2 |
| 6 | I, 25-Dihydroxyvitarnin D3 decreases podocyte loss and podocyte hypertrophy in the subtotaUy nephrectomized rat 显示文摘 | Kuhimann A Haas S Gross L | 2004 | Am J Physiol Renal Physiol2004，286，3： | 1 |
| 7 | The role of cytokines and adhesion molecules for mobilization of peripheral blood stem cell显示文摘 | Kroenwett R Martin S Haas R | 2000 | Stem Cells2000，18，5： | 1 |
| 8 | Flocculation of fine fluorite particles with Corynebacterium xerosis显示文摘 | Haas S R Nascimento F R Schneider I A H | 1999 | Revista de Microbiologia1999，30，： | 1 |
| 9 | O6-Methylguanine-DNA me-thyltransferase activity in breast and brain tumors显示文摘 | Preuss I Eberhagen I Haas S | 1995 | Int J Cancer1995，61，3： | 1 |
| 10 | Continuous flow residence time distribution function characterization显示文摘 | Haas C N Joffe J Heath M S | | 0，，02： | 1 |
| 11 | A case study of airborne culturable microorganisms in a poultry slaughterhouse in Styria, Austria 显示文摘 | Haas D Posch J Schmidt S | 2005 | Aerobiologia2005，21，： | 1 |
| 12 | Adult stem cell therapy in stroke显示文摘 | Haas S Weidner N Winkler J | 2005 | Curr Opin Neurol2005，18，1： | 1 |
| 13 | 显示文摘 | HAAS O HOLZER F MtiLLER S | 2002 | Electro- chimica Acta2002，47，19： | 1 |
| 14 | Assessment of platelet function assays显示文摘 | Nicholson N S Panzer-Knodle S G Haas N F | | 0，，05： | 1 |
| 15 | Total knee arthroplasty for patellofemoral arthritis显示文摘 | Mont MA Haas S Mullick T | 2002 | J Bone Joint Surg(Am)2002，84，11： | 1 |
| 16 | Rituximab added to first - line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma:an East German Study Group Hematology and Oncology Study显示文摘 | Herald M Haas A Stuck S | 2007 | J Clio Oncol2007，25，15： | 1 |
| 17 | Mineralization of vestimentiferan tubes at methane seeps on the Congo deep-sea fan显示文摘 | Haas A Little C T S Sahling H | 2009 | Deep-Sea Research Part I2009，56，： | 1 |
| 18 | The Process of Coping Among Ethnic Mi- nority First - Generation College Freshmen: A Narrative Ap- proach 显示文摘 | Phinney J S Haas K | 2003 | The Journal of Social Psychology2003，143，6： | 1 |
| 19 | Mortality and target haemoglobin concetrat ions in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis显示文摘 | Phrommintikul A Haas S J Elsik M | 2007 | Lancet2007，369，： | 1 |
| 20 | Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric Cancer: a biomarkcr evaluation from the AVAGAST ran- domized phase Ⅲ trial 显示文摘 | van Cutscm E de Haas S Kang YK | 2012 | J Clin Oncol2012，30，17： | 1 |
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