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| 1 | 术前MRI可否显示肝细胞癌的微小血管侵犯?显示文摘微血管是否侵犯对于手术切除肝细胞癌(HCC)是重要的预后影响因素,但术前极少得到评估。本研究的目的是确定可反映组织病理学上肝细胞癌微小血管侵犯的术前MRI表现。对70个HCC病灶的术前马根维显钆贝酸盐增强动脉期4期动态扫描与肝一胆期的MRI影像进行了回顾性复习。 | H.Kim M.S.Park J.Y.Choi Y.N.Park M.J.Kim K.S.Kim 唐光健 | 2009 | 国际医学放射学杂志2009，32，5： | 32 |
| 2 | Periodontitis-induced systemic inflammation exacerbates atherosclerosis partly via endothelial–mesenchymal transition in mice显示文摘Growing evidence suggests close associations between periodontitis and atherosclerosis.To further understand the pathological relationships of these associations,we developed periodontitis with ligature placement around maxillary molars or ligature placement in conjunction with Porphyromonas gingivalis lipopolysaccharide injection at the ligature sites (ligature/P.g.LPS) in Apolipoprotein E knock out mice and studied the atherogenesis process in these animals.The mice were fed with high fat diet for 11 weeks and sacrificed for analyzing periodontitis,systemic inflammation,and atherosclerosis.Controls did not develop periodontitis or systemic inflammation and had minimal lipid deposition in the aortas,but mice receiving ligature or ligature/P.g.LPS showed severe periodontitis,systemic inflammation,and aortic plaque formation.The aortic plaque contained abundant macrophages and cells expressing both endothelial and mesenchymal cell markers.The severity of periodontitis was slightly higher in mice receiving ligature/P.g.LPS than ligature alone,and the magnitude of systemic inflammation and aortic plaque formation were also notably greater in the mice with ligature/P.g.LPS.These observations indicate that the development of atherosclerosis is due to systemic inflammation caused by severe periodontitis.In vitro,P.g.LPS enhanced the secretion of pro-inflammatory cytokines from macrophages and increased the adhesion of monocytes to endothelial cells by upregulating the expression of adhesion molecules from endothelial cells.Moreover,secretory proteins,such as TNF-α,from macrophages induced endothelial–mesenchymal transitions of the endothelial cells.Taken together,systemic inflammation induced by severe periodontitis might exacerbate atherosclerosis via,in part,causing aberrant functions of vascular endothelial cells and the activation of macrophages in mice. | Jin Sook Suh Sol Kim Kristina I.Bostrom Cun-Yu Wang Reuben H.Kim No-Hee Park | 2019 | International Journal of Oral Science2019，11，3： | 15 |
| 3 | The use of 5-alpha reductase inhibitors in the treatment of benign prostatic hyperplasia显示文摘Benign prostatic hyperplasia(BPH)is characterized by an enlarged prostate,lower urinary tract symptoms(LUTS),and a decreased urinary flow rate.Common in older men,BPH is a progressive disease that can eventually lead to complications including acute urinary retention(AUR)and the need for BPH-related surgery.Both normal and abnormal prostate growth is driven by the androgen dihydrotestosterone(DHT),which is formed from testosterone under the influence of 5-alpha reductase.Thus,5-alpha reductase inhibitors(5-ARIs)effectively reduce the serum and intraprostatic concentration of DHT,causing an involution of prostate tissue.Two 5-ARIs are currently available for the treatment of BPHdfinasteride and dutasteride.Both have been demonstrated to decrease prostate volume,improve LUTS and urinary flow rates,which ultimately reduces the risk of AUR and BPH-related surgery.Therefore,either alone or in combination with other BPH medications,5-ARIs are a mainstay of BPH management. | Eric H.Kim John A.Brockman Gerald L.Andriole | 2018 | Asian Journal of Urology2018，5，1： | 11 |
| 4 | 用MR扩散加权成像评价新型凋亡诱导的抗DR-5抗体对异种移植乳腺肿瘤的早期治疗效果显示文摘目的应用MR扩散加权成像评价小鼠乳腺癌模型中应用新型凋亡诱导抗体TRA-8进行治疗的早期治疗反应。方法该动物实验已获得动物实验伦理委员会批准。 | H.Kim D.E.Morgan W.E.Grizzle J.M.Warram C.R.Stockard 冯洁玲 | 2008 | 国际医学放射学杂志2008，31，A06： | 9 |
| 5 | Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids显示文摘A mounting body of evidence indicates that dietary fiber(DF)metabolites produced by commensal bacteria play essential roles in balancing the immune system.DF,considered nonessential nutrients in the past,is now considered to be necessary to maintain adequate levels of immunity and suppress inflammatory and allergic responses.Short-chain fatty acids(SCFAs),such as acetate,propionate,and butyrate,are the major DF metabolites and mostly produced by specialized commensal bacteria that are capable of breaking down DF into simpler saccharides and further metabolizing the saccharides into SCFAs.SCFAs act on many cell types to regulate a number of important biological processes,including host metabolism,intestinal functions,and immunity system.This review specifically highlights the regulatory functions of DF and SCFAs in the immune system with a focus on major innate and adaptive lymphocytes.Current information regarding how SCFAs regulate innate lymphoid cells,T helper cells,cytotoxic T cells,and B cells and how these functions impact immunity,inflammation,and allergic responses are discussed. | Chang H.Kim | 2021 | Cellular & Molecular Immunology2021，18，5： | 8 |
| 6 | 日本的水质标准与水质评价指标显示文摘 | 亀井翼 金兆丰 黄建元 董秉直 M.Kang H.Kim ■田基之 佐藤裕子 真柄泰基 | 2002 | 中国给水排水2002，18，10： | 5 |
| 7 | A cost driven predictive maintenance policy for structural airframe maintenance显示文摘Airframe maintenance is traditionally performed at scheduled maintenance stops.The decision to repair a fuselage panel is based on a fixed crack size threshold,which allows to ensure the aircraft safety until the next scheduled maintenance stop.With progress in sensor technology and data processing techniques,structural health monitoring(SHM) systems are increasingly being considered in the aviation industry.SHM systems track the aircraft health state continuously,leading to the possibility of planning maintenance based on an actual state of aircraft rather than on a fixed schedule.This paper builds upon a model-based prognostics framework that the authors developed in their previous work,which couples the Extended Kalman filter(EKF) with a firstorder perturbation(FOP) method.By using the information given by this prognostics method,a novel cost driven predictive maintenance(CDPM) policy is proposed,which ensures the aircraft safety while minimizing the maintenance cost.The proposed policy is formally derived based on the trade-off between probabilities of occurrence of scheduled and unscheduled maintenance.A numerical case study simulating the maintenance process of an entire fleet of aircrafts is implemented.Under the condition of assuring the same safety level,the CDPM is compared in terms of cost with two other maintenance policies:scheduled maintenance and threshold based SHM maintenance.The comparison results show CDPM could lead to significant cost savings. | Yiwei WANG Christian GOGU Nicolas BINAUD Christian BES Raphael T.HAFTKA Nam H.KIM | 2017 | Chinese Journal of Aeronautics2017，30，3： | 4 |
| 8 | What Causes the Springtime Tropospheric Ozone Maximum over Northeast Asia?显示文摘Scientists have long debated the relative importance of tropospheric photochemical production versus stratospheric influx as causes of the springtime tropospheric ozone maximum over northern mid-latitudes. This paper investigates whether or not stratospheric intrusion and photochemistry play a significant role in the springtime ozone maximum over Northeast Asia,where ozone measurements are sparse.We examine how tropospheric ozone seasonalities over Naha(26°N,128°E),Kagoshima(31°N,131°E),and Pohang(36°N,129°E),which are located on the same meridional line,are related to the timing and location of the jet stream.The ozone seasonality shows a gradual increase from January to the maximum ozone month,which corresponds to April at Naha,May at Kagoshima,and June at Pohang.In order to examine the occurrence of stratospheric intrusion,we analyze a correlation between jet stream activity and tropospheric ozone seasonality.From these analyses,we did not find any favorable evidence supporting the hypothesis that the springtime enhancement may result from stratospheric intrusion.According to trajectory analysis for vertical and horizontal origins of the airmass,a gradual increasing tendency in ozone amounts from January until the onset of monsoon was similar to the increasing ozone formation tendency from winter to spring over China's Mainland,which has been observed during the build-up of tropospheric ozone over Central Europe in the winter-spring transition period due to photochemistry.Overall,the analyses suggest that photochemistry is the most important contributor to observed ozone seasonality over Northeast Asia. | Jae H.KIM Hyunjin LEE | 2010 | Advances in Atmospheric Sciences2010，27，3： | 3 |
| 9 | Prognostic significance of glycaemic control in patients with HBV and HCV‐related cirrhosis and diabetes mellitus显示文摘 | S. Y.Kwon S. S.Kim O. S.Kwon K. A.Kwon M. G.Chung D. K.Park Y. S.Kim Y. S.Koo Y. K.Kim D. J.Choi J. H.Kim | 2005 | Diabetic Medicine2005，，11： | 2 |
| 10 | G protein β3 subunit, interleukin‐10, and tumor necrosis factor‐α gene polymorphisms in Koreans with irritable bowel syndrome显示文摘 | H.‐j.Lee S.‐y.Lee J. E.Choi J. H.Kim I.‐k.Sung H. S.Park C. J.Jin | 2010 | Neurogastroenterology & Motility2010，，7： | 2 |
| 11 | 遗传标记及其在家禽育种中的应用显示文摘 | M.G.Emara H.Kim 吴艳 | 2005 | 中国家禽2005，27，7： | 2 |
| 12 | Xenos peckii vision inspires an ultrathin digital camera显示文摘Increased demand for compact devices leads to rapid development of miniaturized digital cameras.However,conventional camera modules contain multiple lenses along the optical axis to compensate for optical aberrations that introduce technical challenges in reducing the total thickness of the camera module.Here,we report an ultrathin digital camera inspired by the vision principle of Xenos peckii,an endoparasite of paper wasps.The male Xenos peckii has an unusual visual system that exhibits distinct benefits for high resolution and high sensitivity,unlike the compound eyes found in most insects and some crustaceans.The biologically inspired camera features a sandwiched configuration of concave microprisms,microlenses,and pinhole arrays on a flat image sensor.The camera shows a field-of-view(FOV)of 68 degrees with a diameter of 3.4mm and a total track length of 1.4mm.The biologically inspired camera offers a new opportunity for developing ultrathin cameras in medical,industrial,and military fields. | Dongmin Keum Kyung-Won Jang Daniel S.Jeon Charles S.H.Hwang Elke K.Buschbeck Min H.Kim Ki-Hun Jeong | 2018 | Light(Science & Applications)2018，7，1： | 2 |
| 13 | Changes in clinicopathological features and survival after gastrectomy for gastric cancer over a 20‐year period显示文摘 | H. S.Ahn H.‐J.Lee M.‐W.Yoo S.‐H.Jeong D.‐J.Park H.‐H.Kim W. H.Kim K. U.Lee H.‐K.Yang | 2010 | Br J Surg2010，，2： | 2 |
| 14 | Gene–gene interaction between interleukin‐4 and interleukin‐4 receptor α in Korean children with asthma显示文摘 | S.‐G.Lee B.‐S.Kim J.‐H.Kim S.‐Y.Lee S.‐O.Choi J.‐Y.Shim T.‐J.Hong S.‐J.Hong | 2004 | Clinical & Experimental Allergy2004，，8： | 1 |
| 15 | The relationship between insulin resistance and dyslipidaemia in cigarette smokers显示文摘 | H. M. F.Farin F.Abbasi S. H.Kim C.Lamendola T.McLaughlin G. M.Reaven | 2006 | Diabetes Obesity and Metabolism2006，，1： | 1 |
| 16 | Preoperative inflammation is a prognostic factor for gallbladder carcinoma显示文摘 | H.‐S.Han J. Y.Cho Y.‐S.Yoon K. S.Ahn H.Kim | 2010 | Br J Surg2010，，1： | 1 |
| 17 | Factors affecting the quality of life in patients with epilepsy in Seoul, South Korea显示文摘 | S.Choi‐Kwon C.Chung H.Kim S.Lee S.Yoon H.Kho J.Oh S.Lee | 2003 | Acta Neurologica Scandinavica2003，，6： | 1 |
| 18 | Prevalence of and risk factors for extracranial internal carotid artery stenosis in Korean Type?2 diabetic patients显示文摘 | J. H.Park W. H.Kim J. H.Kim T. S.Park H. S.Baek | 2006 | Diabetic Medicine2006，，12： | 1 |
| 19 | Attachment and biofilm formation on stainless steel by Escherichia coli O157:H7 as affected by curli production显示文摘 | J.‐H.Ryu H.Kim J.F.Frank L.R.Beuchat | 2004 | Letters in Applied Microbiology2004，，4： | 1 |
| 20 | Enhanced degradation and toxicity reduction of dihexyl phthalate by Fusarium oxysporum f. sp. pisi cutinase显示文摘 | Y.‐H.Kim H.‐S.Seo J.Min Y.‐C.Kim Y.‐H.Ban K.Y.Han J.‐S.Park K.‐D.Bae M.B.Gu J.Lee | 2006 | Journal of Applied Microbiology2006，，1： | 1 |
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