|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 血清乙型肝炎病毒DNA水平的生物学梯度与肝细胞肝癌的风险性相关显示文摘Context: Serum hepatitis B virus (HBV) DNA level is a marker of viral replication and efficacy of antiviral treatment in individuals with chronic hepatitis B. Objective: To evaluate the relationship between serum HBV DNA level and risk of hepatocellular carcinoma. Design, Setting, and Participants: Prospective cohort study of 3653 participants (aged 30-65 years), who were seropositive for the hepatitis B surface antigen and seronegative for antibodies against the hepatitis C virus, recruited to a community-based cancer screening program in Taiwan between 1991 and 1992. Main Outcome Measure: Incidence of hepatocellular carcinoma during follow-up examination and by data linkage with the national cancer registry and the death certification systems. Results: There were 164 incident cases of hepatocellular carcinoma and 346 deaths during a mean follow-up of 11.4 years and 41 779 person-years of follow-up. The incidence of hepatocellular carcinoma increased with serum HBV DNA level at study entry in a dose-response relationship ranging from 108 per 100 000 person-years for an HBV DNA level of less than 300 copies/mL to 1152 per 100 000 person-years for an HBV DNA level of 1 million copies/mL or greater. The corresponding cumulative incidence rates of hepatocellular carcinoma were 1.3%and 14.9%, respectively. The biological gradient of hepatocellular carcinoma by serum HBV DNA levels remained significant (P< .001) after adjustment for sex, age, cigarette smoking, alcohol consumption, serostatus for the hepatitis B e antigen (HBeAg), serum alanine aminotransferase level, and liver cirrhosis at study entry. The dose-response relationship was most prominent for participants who were seronegative for HBeAg with normal serum alanine aminotransferase levels and no liver cirrhosis at study entry. Participants with persistent elevation of serum HBV DNA level during follow-up had the highest hepatocellular carcinoma risk. Conclusion: Elevated serum HBV DNA level (>10 000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis. | Chen C.-J. Yang H. -I. Su J. 王铮(译) 陈云茹(校) | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，6： | 204 |
| 2 | Crustal structure of the northeastern Tibetan plateau,the Ordos block and the Sichuan basin from ambient noise tomography显示文摘We apply ambient noise tomography to significant seismic data resources in a region including the northeastern Tibetan plateau,the Ordos block and the Sichuan basin.The seismic data come from about 160 stations of the provincial broadband digital seismograph networks of China.Ambient noise cross-correlations are performed on the data recorded between 2007 and 2009 and high quality inter-station Rayleigh phase velocity dispersion curves are obtained between periods of 6 s to 35 s.Resulting Rayleigh wave phase velocity maps possess a lateral resolution between 100 km and 200 km.The phase velocities at short periods (<20 s) are lower in the Sichuan basin,the northwest segment of the Ordos block and the Weihe graben,and outline sedimentary deposits.At intermediate and long periods (>25 s),strong high velocity anomalies are observed within the Ordos block and the Sichuan basin and low phase velocities are imaged in the northeastern Tibetan plateau,reflecting the variation of crustal thickness from the Tibetan plateau to the neighboring regions in the east.Crustal and uppermost mantle shear wave velocities vary strongly between the Tibetan plateau,the Sichuan basin and the Ordos block.The Ordos block and the Sichuan basin are dominated by high shear wave velocities in the crust and uppermost mantle.There is a triangle-shaped low velocity zone located in the northeastern Tibetan plateau,whose width narrows towards the eastern margin of the plateau.No low velocity zone is apparent beneath the Qinling orogen,suggesting that mass may not be able to flow eastward through the boundary between the Ordos block and the Sichuan basin in the crust and uppermost mantle. | Yong Zheng Yingjie Yang Michael H. Ritzwoller Xiufen Zheng Xiong Xiong Zuning Li | 2010 | Earthquake Science2010，23，5： | 43 |
| 3 | Three dimensional shear wave velocity structure of the crust and upper mantle beneath China from ambient noise surface wave tomography显示文摘We determine the three-dimensional shear wave velocity structure of the crust and upper mantle in China using Green's functions obtained from seismic ambient noise cross-correlation.The data we use are from the China National Seismic Network,global and regional networks and PASSCAL stations in the region.We first acquire cross-correlation seismograms between all possible station pairs.We then measure the Rayleigh wave group and phase dispersion curves using a frequency-time analysis method from 8 s to 60 s.After that,Rayleigh wave group and phase velocity dispersion maps on 1° by 1° spatial grids are obtained at different periods.Finally,we invert these maps for the 3-D shear wave velocity structure of the crust and upper mantle beneath China at each grid node.The inversion results show large-scale structures that correlate well with surface geology.Near the surface,velocities in major basins are anomalously slow,consistent with the thick sediments.East-west contrasts are striking in Moho depth.There is also a fast mid-to-lower crust and mantle lithosphere beneath the major basins surrounding the Tibetan plateau (TP) and Tianshan (Junggar,Tarim,Ordos,and Sichuan).These strong blocks,therefore,appear to play an important role in confining the deformation of the TP and constraining its geometry to form its current triangular shape.In northwest TP in Qiangtang,slow anomalies extend from the crust to the mantle lithosphere.Meanwhile,widespread,a prominent low-velocity zone is observed in the middle crust beneath most of the central,eastern and southeastern Tibetan plateau,consistent with a weak (and perhaps mobile) middle crust. | Xinlei Sun Xiaodong Song Sihua Zheng Yingjie Yang Michael H. Ritzwoller | 2010 | Earthquake Science2010，23，5： | 28 |
| 4 | Schistosoma japonicum egg antigens stimulate CD4(+) CD25(+) T cells and modulate airway inflammation in a murine model of asthma显示文摘 | Yang, J. H. Zhao, J. Q. Yang, Y. F. Zhang, L. Yang, X. Zhu, X. Ji, M. J. Sun, N. X. Su,C. | 2007 | 南京医科大学学报(自然科学版)2007，27，4： | 25 |
| 5 | EFFECT OF Zr ADDITION TO Ti-KILLED STEEL ON INCLUSION FORMATION AND MICROSTRUCTURAL EVOLUTION IN WELDING INDUCED COARSE-GRAINED HEAT AFFECTED ZONE显示文摘化学部件和忍受 Ti 包括的尺寸分发上的锆的效果,赞成了导致的、纹理粗糙的热影响了的焊接的谷物精炼地区(CGHAZ ) 与在杀死 Ti 的钢提高了影响坚韧,它基于试验性的观察和热力学的计算被检验。它显示包括的化学成分逐渐地从 Ti-O 氧化物变化了到 Ti-O+Zr-O 复合氧化物和 ZrO2 氧化物的一个单个阶段,作为内容从零增加了到 0.0100% 的 Zr。 Zr 的踪迹(0.0030%0.0080%,在液体钢取决于氧内容)因为 ZrO2 氧化物的更大的特定的密度,为 Ti 氧化物提供了大量起核心作用的核心,并且生产了有利的包括的小尺寸分布因为有在 CGHAZ 的高成核率的针状的铁酸盐转变,和针状的铁酸盐的大量的部分在 CGHAZ 被获得,与提高的影响坚韧。否则, Zr (0.0100%) 的一个高内容生产了单个阶段 ZrO2,它是无力的起核心作用由铁酸盐方面板组成的针状的铁酸盐和谷物边界铁酸盐在 CGHAZ 发展了。试验性的结果被热力学的计算证实。 | F. Chai C.F. Yang H. Su Y.Q. Zhang Z. Xu Y.H. Yang | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，3： | 18 |
| 6 | 抑郁症:应用MR动脉自旋标记法检测局部脑灌注变化显示文摘目的应用动脉自旋标记法(ASL)检测难治性抑郁症(RDD)、非难治性抑郁症(NDD)的局部脑灌注变化,并与健康对照组比较。方法本研究得到了当地伦理委员会批准,所有参加本研究的病人及志愿者均签署知情同意书。24例RDD、37例NDD以及42例健康对照者参加了本研究。从2006年2月-2007年7月.所有参与者均应用3TMR成像系统进行检查。对ASL和回波平面成像进行减影和平均以获得灌注加权像。采用基于体素的方法进行分析。感兴趣区放置在双侧海马、丘脑及豆状核。 | S. Lui L.M. Parkes X. Huang K. Zou R.C. Chore H. Yang 夏爽(译) 祁吉(校) | 2009 | 国际医学放射学杂志2009，32，4： | 18 |
| 7 | Computational Research on Modular Undulating Fin for Biorobotic Underwater Propulsor显示文摘Biomimetic design employs the principles of nature to solve engineering problems. Such designs which are hoped to be quick,efficient,robust,and versatile,have taken advantage of optimization via natural selection. In the present research,an environment-friendly propulsion system mimicking undulating fins of stingray was built. A non-conventional method was considered to model the flexibility of the fins of stingray. A two-degree-of-freedom mechanism comprised of several linkages was designed and constructed to mimic the actual flexible fin. The driving linkages were used to form a mechanical fin con-sisting of several fin segments,which are able to produce undulations,similar to those produced by the actual fins. Owing to the modularity of the design of the mechanical fin,various undulating patterns can be realized. Some qualitative observations,obtained by experiments,predicted that the thrusts produced by the mechanical fin are different among various undulating patterns. To fully understand this experimental phenomenon is very important for better performance and energy saving for our biorobotic underwater propulsion system. Here,four basic undulating patterns of the mechanical fin were performed using two-dimensional unsteady computational fluid dynamics (CFD) method. An unstructured,grid-based,unsteady Navier-Stokes solver with automatic adaptive re-meshing was used to compute the unsteady flow around the fin through twenty complete cycles. The pressure distribution on fin surface was computed and integrated to provide fin forces which were decomposed into lift and thrust. The pressure force and friction force were also computed throughout the swimming cycle. Finally,vortex contour maps of these four basic fin undulating patterns were displayed and compared. | Yong-hua Zhang Lai-bing Jia Shi-wu Zhang Jie Yang K. H. Low | 2007 | Journal of Bionic Engineering2007，4，1： | 17 |
| 8 | Soil Phosphorus Distribution as Affected by Irrigation Methods in Plastic Film House显示文摘Water-saving irrigation methods have been increasingly used for vegetable cultivation in greenhouse or plastic film house.However,there is limited information concerning the effect of water-saving irrigation methods on soil phosphorus (P)behavior.In this experiment,drip and subsurface irrigation methods were applied,with furrow irrigation method as control,in Mollic Gleysols.Soil P distribution throughout the depth was significantly affected by irrigation methods.Total, Olsen,organic and inorganic P contents were greater in the topsoil(0–10 and 10–20 cm)than in the subsoil(20–30,30–40, 40–50 and 50–60 cm).The Olsen P content throughout 0–60 cm layer under drip and subsurface irrigation treatments was lower than that under the furrow irrigation treatment.However,the total,organic and inorganic P contents from 20 to 60 cm under drip irrigation treatment were higher than or close to those under furrow irrigation treatment,but were lower under subsurface irrigation treatment than under furrow irrigation treatment.Under subsurface irrigation treatment,the contents of total,organic and inorganic P at the 0–10 cm layer were 78.0%,1.3% and 3.7% greater than those at the 10–20 cm layer,respectively.But Olsen P content at the 10–20 cm layer was 5.7% larger than that at the 0–10 cm layer.These suggested that soil P behavior could be manipulated by soil water management to some extent. | YANG Li-Juan ZHANG Yu-Long LI Fu-Sheng J. H. LEMCOFF | 2011 | Pedosphere2011，21，6： | 14 |
| 9 | Electromagnetoelastic behaviors of functionally graded piezoelectric solid cylinder and sphere显示文摘电镀物品上的分析研究磁电的行为为稳固的柱体和范围在一个一致磁场放了并且使遭到了到外部压力并且电的装载的机能上地分级的压电的材料(FGPM ) 被介绍。什么时候机械,电并且材料的磁性在 FGPM 稳固的柱体在磁场向量的光线的方向,准确排水量,压力,电的潜力和不安遵守一条相同幂定律,范围被使用 electromagnetoelasticity 的无穷小的理论获得。数字例子也显示出材料不同类的重要影响。注意选择不同类参数 β
的特定的值能优化电镀物品有趣磁电的回答,它将具有在现代工程图案的特别重要性。 | H. L. Dai Y.M. Fu J.H. Yang | 2007 | Acta Mechanica Sinica2007，23，1： | 10 |
| 10 | Late Cretaceous biota and the Cretaceous-Paleogene(K--Pg)Boundary in Jiayin of Heilongjiang,China显示文摘An international cooperative study of the Late Cretaceous biota and non-marine strata including the Cretaceous-Paleogene(K--Pg) boundary in Jiayin near the Heilongjiang River,China during 2002-2010,is summarized in this paper. The strata includes the Upper Cretaceous Yong'ancun-,Taipinglinchang-,Yuliang-zi-,and Furao formations,and the Paleocence Wuyun Formation consisting of Baoshantou Member and a Coalbearing Member. Seven palynological assemblages from Santonian to Paleocene are recognized,which is used for definition of the K--Pg boundary. Through the palynological analysis of three drilled boreholes (XHY-2005,2006,2008) in Xiaoheyan of western Jiayin,the K--Pg boundary is defined within 20. 00-20. 05 m in the borehole XHY-2006 (as a standard boundary) which is just between the top of Furao Formation (late Maasterichtian) and the base of Baishantou Member (early Danian) . These new research results are supported by paleo- magnetic,geochemical and other analyses,also. On the other hand,the presence of eight taxa of Maasterichtian dinosaurs (mostly hadrosaurids) have been recognized by the authors; and two mega-plant assemblages from the Yong'ancun Fm (Santonian) to Taipinglinchang Fm (Campanian) are confirmed. These research a-chievements indicate that the Upper Cretaceous-Paleocene in Jiayin can be well correlated to the strata in the neighboring Zeya-Bureja basin,Russia. The K--Pg boundary definited in Jiayin is the first well documented non-marine K--Pg boundary in China. Also the related paleoclimate,paleoenvironment and the mass extinctions in this area during the Cretaceous-Paleocene transition are also discussed. | Sun G. Akhmetiev M. Markevich V. Ashraf A. R. Bugdaeva E. Godefroit P. Bolotsky Yu. Dong Z. M. Golovneva L. Yang H. X. Sun C. L. Sun Y. W. Quan C. Kodrul T. Kezina T. Johnson K. Nishida H Dilcher D. L. Harding I. Chen Y. J. | 2011 | Global Geology2011，14，3： | 9 |
| 11 | Gly(82)Ser polymorphism of the receptor for advanced glycation end products is associated with an increased risk of gastric cancer in a Chinese population显示文摘 | Gu, H.J. Yang, L. Sun, Q. M. Zhou, B. Tang, N. P. Cong, R. H. Zeng, Y. Wang, B. | 2008 | 南京医科大学学报(自然科学版)2008，28，9： | 9 |
| 12 | Numerical and Experimental Research on Modular Oscillating Fin显示文摘Fishes are famous for their ability to position themselves accurately even in turbulent flows. This ability is the result of the coordinated movement of fins which extend from the body. We have embarked on a research program designed to develop an agile and high efficient biologically inspired robotic fish based on the performance of hybrid mechanical fins. To accomplish this goal, a mechanical ray-like fin actuated by Shape Memory Alloy (SMA) is developed, which can realize both oscillatory locomotion and undulatory locomotion. We first give a brief introduction on the mechanical structure of our fin and then carry out theoretic analysis on force generation. Detailed information of these theoretical results is later revealed by Computational Fluid Dynamic (CFD), and is final validated by experiments. This robotic fin has potential application as a propulsor for future underwater vehicles in addition to being a valuable scientific instrument. | Yong-hua Zhang Yan Song Jie Yang K. H. Low | 2008 | Journal of Bionic Engineering2008，5，1： | 8 |
| 13 | Mouse models of colorectal cancer显示文摘Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models. However, none recapitulates all of the characteristics of human colorectal cancer. It is critical to use a specific mouse model to address a particular research question. Here, we review commonly used mouse models for human colorectal cancer. | Yunguang Tong Wancai Yang H. Phillip Koeffler | 2011 | Chinese Journal of Cancer2011，30，7： | 7 |
| 14 | 行人膝关节韧带的建模及验证研究显示文摘基于人体模型THUMS中的膝韧带模型,改进了材料参数和单元属性。采用近年较新的生物力学实验数据,逐个验证韧带模型在不同应变率下的生物逼真度。结果表明,膝韧带ACL、PCL、MCL和LCL在不同应变率下的拉力与位移关系曲线与试验结果吻合较好,说明模型具有较好的生物逼真度,能较准确地模拟韧带的损伤和拉伸响应。 | 张冠军 曹立波 官凤娇 张勇 Yang King H. | 2012 | 汽车工程2012，34，1： | 7 |
| 15 | MHD and kinetic analysis of flow bursts in the Earth's plasma sheet显示文摘In an attempt to study the flow bursts in the Earth’s plasma sheet we select an event that took place on August 7,2004 in the expansion phase of a substorm,using data from the geomagnetic index,solar wind data,plasma and magnetic field observations from C1 Cluster satellite(the Cluster mission has 4 satellites)and from Double Star TC-1 satellite.In MHD approach,TC-1 firstly observed the tailward flow,then the earthward,and finally the flow alternated in two directions.C1 firstly observed the earthward plasma flow,and then the tailward plasma flow.Before flow bursts are observed by TC-1 and C1,there are disturbances in local entropy with their tailward local entropy larger than those of the earthward.The kinetic features of the plasma flow observed by C1 are similar to those in MHD.However,kinetic characteristics of the plasma flow observed by TC-1 are far more than the description in MHD.The inadequacy mainly exists in two cases:(i)the firstly enhanced tailward flows given in MHD are found without significant increase of the energetic tailward flux;(ii)the almost stagnant flow in MHD is composed of the enhanced energetic ion flux in both earthward and tailward directions.The earthward flow burst observed by TC-1 might be multiple overshoots and rebounds.The earthward flow burst observed by C1 might be simply rebounded in the near-Earth.The pulsation observed by C1 is earlier than that observed by TC-1 with the former intensity less than that of the latter.After the energetic ion flux in the tailward direction is significantly enhanced,the power spectrum intensity of the ULF wave commences to increase obviously,which may suggest that the stream instability is closely correlated with ULF pulsations. | MA YuDuan CAO JinBin FU HuiShan REME H. DANDOURAS I. YANG JunYing WANG ZhiQiang TAO Dan YANG Jian | 2014 | Science China(Technological Sciences)2014，57，1： | 7 |
| 16 | Microstructure and mechanical properties of AZ61 Mg alloy prepared by multi directional forging显示文摘AZ61Mg alloy was multi directionally forged(MDFed) during decreasing temperature condition from 643 K to 483 K at a true strain rate of 3×10-3 s-1 up to cumulative strain of∑△ε=4.0 at maximum.A pass strain of△ε=0.8 was employed.While average grain size decreased gradually with increasing cumulative strain,the evolution of fine-grained structure strongly depended on the MDF temperature.Under the condition where the temperature was higher than the most adequate one,grain coarsening partially took place during MDF.In contrast,at lower temperature,inhomogeneous microstructure composed of the initial coarse and newly appeared fine grains was evolved.After straining over∑△ε=3.2(i.e.,over 4 passes of MDF) ,equiaxed ultrafine grains(UFGs) having average size of about and lower than 1μm were uniformly evolved.While the MDFed alloy to∑△ε=4.0 possessed relatively high hardness of HV 99,and it accepted further about 20%cold rolling almost without cracking.Because of the superior formability of the UFGed AZ61Mg alloy,the hardness was further easily raised to HV 120 by following cold rolling. | H. MIURA G. YU X. YANG T. SAKAI | 2010 | Transactions of Nonferrous Metals Society of China2010，20，7： | 7 |
| 17 | INTERNAL OXIDATION KINETICS &DIFFUSION MECHANISM OF OXYGEN IN Cu-Al SINTERED ALLOY显示文摘INTERNALOXIDATIONKINETICS&DIFFUSIONMECHANISMOFOXYGENINCu-AlSINTEREDALLOY￥S.G.Tian;L.T.Zhang;H.M.Shao;L.J.Zou;T.F.Li;andH.C.Ya... | S.G. Tian L.T. Zhang H. M. Shao L.J. Zou T.F. Li and H. C. Yang (Department of Materials Science, Shenyang Polytechnic University, Shenyang 110023, China) (Corrosion Science Laboratory, Institute of Corrosion and Protection of Metals, Chinese Academy | 1996 | Acta Metallurgica Sinica(English Letters)1996，9，5： | 6 |
| 18 | Refining constitutive relation by integration of finite element simulations and Gleeble experiments显示文摘Thermo-mechanical coupled finite element calculations were carried out to simulate the Gleeble compression of the samples of a titanium alloy(Ti60), and the results are analyzed and compared with the actual compression tests conducted on a Gleeble 3800 thermo-mechanical simulator. The changes in temperature, stress and strain distribution in the samples and the source of error on the constitutive relations from Gleeble hot compression test were analyzed in detail. Both simulations and experiments showed that the temperature distribution in the specimen is not uniform during hot compression, resulting in significant deformation inhomogeneity and non-ignorable error in the flow stress strain relation,invalidating the uniform strain assumption commonly assumed when extracting the constitutive relation from Gleeble tests. Based on the finite element simulations with iterative corrections, we propose a scheme to refine the constitutive relations from Gleeble tests. | D.J. Yu D.S. Xu H. W ang Z.B. Zhao G.Z. Wei R. Yang | 2019 | Journal of Materials Science & Technology2019，35，6： | 6 |
| 19 | Inactivation of infectious bursal disease virus by binary ethylenimine and formalin显示文摘In this experiment conducted to study the inactivation dynamics of infectious bursal disease virus (IBDV) by binary ethylenimine (BEI) in comparison with formalin, IBDV was isolated from the bursa of infected chickens and its confirmation was done by agar gel precipitation test. Viral suspensions were subjected to inactivation with BEI and formalin for pre-set time in-tervals. BEI was employed at concentrations of 0.001 and 0.002 mol/L while formalin was used at 0.1% and 0.2%. Sampling was done at 6, 12, 24, 36 and 48 h of incubation and samples were tested for their inactivation status in 9-day-old embryonated eggs and 3-week-old broiler chickens. IBDV was completely inactivated by 0.001 and 0.002 mol/L BEI after 36 h of incubation at 37 °C, whereas formalin at 0.1% and 0.2% concentrations inactivated IBDV in 24 h. | HABIB M. HUSSAIN I. FANG W.H. RAJPUT Z.I. YANG Z.Z. IRSHAD H. | 2006 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2006，7，4： | 6 |
| 20 | 行人膝关节有限元模型的建立与验证显示文摘在前期研究中对下肢长骨和膝关节主要韧带的模型进行了全面验证的基础上,建立了具有详细解剖学结构的行人膝关节有限元模型,并定义了各组织间的接触。依据更符合实际行人事故中膝关节载荷特点的生物力学实验,对膝关节有限元模型进行了动态四点弯曲和动态三点弯剪仿真验证。结果显示膝关节模型的生物力学响应与实验结果吻合,能较好地反映膝关节的损伤和动力学响应,具有较好的生物逼真度。 | 张冠军 魏嵬 曹立波 王俊霞 Yang King H. | 2014 | 汽车工程2014，36，9： | 5 |
您所在的机构暂未开通此部分的功能，请联系管理员