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| 1 | Proximal gastric response to small intestinal nutrients is abnormal in mechanically ventilated critically ill patients显示文摘瞄准:在非常有病的病人决定近似的胃的反应到小肠的营养素。方法:近似胃的活动性在 13 个非常有病的病人被测量(49.3 +/- 4.7 年) 并且 12 个健康志愿者(27.7 +/- 2.9 年) 用一种 barostat 技术。记录在基线被执行,在 60-min 期间 intra 十二指肠的注入保证(2 kcal/min ) ,并且为跟随注入的 2 h。最小的扩张压力(MDP ) , intra 袋子体积和底的波浪活动是坚定的。结果:MDP 在病人是更高的(11.7 +/- 1.1 对 7.8 +/- 0.7 毫米汞柱;P <
0.01 ) 。基线 intra 袋子体积在 2 个组是类似的。在健康题目,一“双性人形式”近似胃的体积反应被观察。在病人,近似胃的体积的起始的增加小、推迟,但是最后到达了类似于健康题目的最大的体积。在健康题目,近似胃的体积很快在滋养的注入以后回到了基线水平(中部 18 min ) 。相反,到基线的体积的恢复在非常有病的病人被推迟(中部 106 min ) 。在 6 个病人,体积没在滋养的注入以后回到基线水平 2 小时。在病人,底的体积波浪是不太经常的(P <
0.05 ) 并且有的更低的振幅(P <
0.001 ) ,与健康题目相比。结论:在重病,对小肠的滋养的刺激的近似胃的马达回答是反常的。 | Nam Q Nguyen Robert J Fraser Marianne Chapman Laura K Bryant Richard H Holloway Rosalie Vozzo Christine Feinle-Bisset | 2006 | World Journal of Gastroenterology2006,12,27: | 3 |
| 2 | Proximal gastric motility in critically ill patients with type 2 diabetes mellitus显示文摘AIM: To investigate the proximal gastric motor response to duodenal nutrients in critically ill patients with long- standing type 2 diabetes mellitus. METHODS: Proximal gastric motility was assessed (using a barostat) in 10 critically ill patients with type 2 diabetes mellitus (59 ± 3 years) during two 60-min duodenal infusions of Ensure? (1 and 2 kcal/min), in random order, separated by 2 h fasting. Data were compared with 15 non-diabetic critically ill patients (48 ± 5 years) and 10 healthy volunteers (28 ± 3 years). RESULTS: Baseline proximal gastric volumes were similar between the three groups. In diabetic patients, proximal gastric relaxation during 1 kcal/min nutrient infusion was similar to non-diabetic patients and healthy controls. In contrast, relaxation during 2 kcal/ min infusion was initially reduced in diabetic patients (P < 0.05) but increased to a level similar to healthy humans, unlike non-diabetic patients where relaxation was impaired throughout the infusion. Duodenal nutrient stimulation reduced the fundic wave frequency in a dose-dependent fashion in both the critically ill diabetic patients and healthy subjects, but not in critically ill patients without diabetes. Fundic wave frequency in diabetic patients and healthy subjects was greater than in non-diabetic patients. CONCLUSION: In patients with diabetes mellitus, proximal gastric motility is less disturbed than non- diabetic patients during critical illness, suggesting that these patients may not be at greater risk of delayed gastric emptying. | Nam Q Nguyen Robert J Fraser Laura K Bryant Marianne Chapman Richard H Holloway | 2007 | World Journal of Gastroenterology2007,13,2: | 3 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017,25,5: | 2 |
| 4 | Endocrine regulation of menstruation 显示文摘 | Jabbour H N Kelly R W Fraser H M | 2006 | Endocr Rew2006,27,1: | 1 |
| 5 | Alternative splicing of the human luteal LH receptor during luteolys- is and maternal recognition of pregnancy 显示文摘 | Madhra M Gay E Fraser H M | 2004 | Mol Hum Reprod2004,10,: | 1 |
| 6 | A comparison between ranolazine and CVT-d325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion 显示文摘 | Wang P Fraser H Lloyd SG | 2007 | J Pharmacol Exp Ther2007,321,1: | 1 |
| 7 | Observational study of maternal anthropometry and fetal insulin显示文摘 | Soltani-K H Bruce C Fraser RB | 1999 | Arch Dis Child fetal Neonatal ED1999,81,2: | 1 |
| 8 | A test of four plant species to reduce total nitrogen and total phosphorus from soil leachate in subsurface wetland microcosms显示文摘 | Lauchlan H Fraser Spring M Carty David Steer | 2004 | Bioresour Technol2004,94,: | 1 |
| 9 | Independent coordinates for strange attractors from mutual information显示文摘 | Fraser A M Swinney H L | 1986 | Phy Rev A1986,,33: | 1 |
| 10 | Single injections of vascular endothelial growth factor trap block ovulation in the macaque and produce a prolonged,dose-related suppression of ovarian function显示文摘 | Fraser HM Wilson H Rudge JS | 2005 | Journal of Clinical Endocrinology & Metabolism2005,90,2: | 1 |
| 11 | Independent coordinates for strange attractors from mutual information 显示文摘 | Fraser A M Swinney H L | 1986 | Phys Rev A1986,33,: | 1 |
| 12 | Localization of mrna for vascular endothelial growth factor (Vegf), angio- poietins and their receptors during the peri-implanta- tion period and early pregnancy in marmosets (Cal- lithrix Jacchus) 显示文摘 | Rowe A J Wulff C Fraser H M | 2003 | Reproduction2003,126,2: | 1 |
| 13 | Minimal access versus open transforaminal lumbar interbody fusion: meta-analysis of fusion rates 显示文摘 | Wu R H Fraser J F Hrtl R | 2010 | Spine2010,35,26: | 1 |
| 14 | EST-derived microsatellites from A ctinidia species and their potential for mapping显示文摘 | FRASER L G HARVEY C F CROWHURST R N DE SILVA H N | 2004 | Theor Appl Genet2004,108,: | 1 |
| 15 | Detection of Echinococcus granulosus coproantigens in Australian canidswith natural or experimental infection显示文摘 | Jenkins DJ Fraser A Bradshaw H | 2000 | J Parasitol2000,86,1: | 1 |
| 16 | A method for detecting large-scale forest cover change using coarse spatial resolution imagery显示文摘 | Fraser R H Abuelgasim A Latifovic R | 2005 | Remote Sensing of Environment2005,95,4: | 1 |
| 17 | Functionalised β-diketonate polynuclear lanthanoid hydroxo clusters:Synthesis,characterization,and magnetic properties显示文摘 | Andews P C Beck T Fraser B H | 2009 | Polyhedron2009,28,: | 1 |
| 18 | Suppression of luteal angiogenesis in the primate after neutralization of vascular endo- thelial growth factor 显示文摘 | Fraser H M Dickson S E Lunn S F | 2000 | Endocrinology2000,141,3: | 1 |
| 19 | The interacting effects of temperature and plant community type on nutrient removal in wetland microcosms显示文摘 | PICARD C R FRASER L H SIEER D | 2005 | Bioresource Technology2005,96,9: | 1 |
| 20 | Independent coordinates for strange attractors from mutual information显示文摘 | Fraser A M Swinney H L | 1986 | Physical Review A1986,33,2: | 1 |