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| 1 | Clinical significance of granuloma in Crohn's disease显示文摘AIM: Granuloma is considered the hallmark of microscopic diagnosis in Crohn's disease (CD), but granulomas can be detected in only 21-60% of CD patients. The aim of this studywas to evaluate the frequency of granulomas by multiple endoscopic biopsies in patients with CD and to examine whether group of patients with or without granuloma exhibit a different clinical course.METHODS: Fifty-six patients with newly diagnosed Cdwere included in the study. Jejunoscopy, enteroclysis and ileo-colonoscopy were performed in all patients. At least two biopsy specimens from each examined gastrointestinal segment were examined microscopically searching granuloma. The clinical course was followed in all patients, and extraintestinal manifestations as well as details of any immunosuppressive therapy and surgical intervention were noted.RESULTS: Granuloma was found in 44.6% of the cases (25 patients). Patients with granuloma had higher activity parameters at the time of the biopsies. Extraintestinal manifestations were observed and surgical interventions were performed more often in the granuloma group. The need of immunosuppressive therapy was significantly more frequent in the patients with granuloma. Granuloma formation is more often seen in younger patients, and mainly in the severe, active penetrating disease. CONCLUSION: The significantly higher frequency of surgical interventions and immunosuppressive therapy suggests that granuloma formation is associated with a more severe disease course during the first years of CD. | Tamás Molnár László Tiszlavicz Csaba Gyulai Ferenc Nagy János Lonovics | 2005 | World Journal of Gastroenterology2005，11，20： | 5 |
| 2 | Callus initiation and plant regeneration from inflorescence primordia of the intergeneric hybrid Agropyron repens (L.) Beauv.xBromus inermis Leyss. cv. nanus on a modified nutritive medium显示文摘 | G. Gyulai J. Janovszky E. Kiss L. Lelik A. Csillag L. E. Heszky | 1992 | Plant Cell Reports (-)1992，，5： | 1 |
| 3 | Milkrun Vehicle Routing Approach for Shopfloor Logistics显示文摘 | Gyulai D Pfeiffer A Sobottka T | 2013 | Procedia CIRP2013，1，7： | 1 |
| 4 | Exhaled biomarkers in lung cancer显示文摘 | Horveth I Lezatr Z Gyulai N | 2009 | Eur Respir J2009，34，1： | 1 |
| 5 | Dysfunctional blood and target tissue CD4^+ CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation显示文摘 | Sugiyama H Gyulai R Toichi E | 2005 | J Immunol2005，174，1： | 1 |
| 6 | Dysfunctional blood and tar- get tissue CD4 + CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation 显示文摘 | Sugiyama H Gyulai R Toiehi E | 2005 | J Immuno12005，174，1： | 1 |
| 7 | Cytotoxic T lymphocyte (CTL) responses to human cytomegalovirus pp65,IE1-exon4, gB, pp150, and pp28 in healthy individuals :revaluation of prevalence of IE1-specific CTLs显示文摘 | Gyulai Z Endresz V Burian K | 2000 | J Infect Dis2000，181，5： | 1 |
| 8 | Maintenance treatment outcomes in older patients with bipolar I disorder显示文摘 | SAJATOVIC M GYULAI L CALABRESE JR | 2005 | Am J Geriatr Psychiatry2005，13，4： | 1 |
| 9 | A novel method for rapid micropropagation of pineapple显示文摘 | KISS E KISS J GYULAI G | 1995 | HortScienee1995，30，： | 1 |
| 10 | A comparison of clinical assessment and home oximetry in the diagnosis of obstructive sleep apnea显示文摘 | Gyulay S Olson LG Hensley MJ | 1993 | Am Rev Respir Dis1993，147，1： | 1 |
| 11 | Dysfunctional blood and target tissue CD4^+CD25^high regulatory T cells in psoriasis:mechanism underlying unrestrained pathogenic effector T cell proliferation显示文摘 | Sugiyama H Gyulai R Toichi E | 2005 | J Immunol2005，174，1： | 1 |
| 12 | Dysfunctional blood and target tissue CD4+CD25 regulatory T cells in psoriasis:mechanism underlying unrestrained pathogenic effector T cell proliferation显示文摘 | Suigiyama H Gyulai R Toichi E | 2005 | J Immunol2005，174，1： | 1 |
| 13 | Geoelectric determination of quality changes and tectonic disturbances in coal deposits显示文摘 | CAOKAS J DOBROKA M GYULAI A | 1986 | Geophysical Prospecting1986，34，7： | 1 |
| 14 | The changing epitomeof species identification - DNA barcoding 显示文摘 | Ajmal Ali M Gyulai G Hidvegi N | 2014 | Saudi J Biol Sci2014，21，3： | 1 |
| 15 | The current understanding of lamotrigine as a mood stabilizer显示文摘 | Hahn CG Gyulai L Baldassano CF | 2004 | J Clin Psychiatry2004，65，6： | 1 |
| 16 | Cytotoxic T lymphocyte (CTL) responses to human cytomegalovirus pp65, IE1Exon 4, gB, ppl50, and pp28 in healthy individuals: reevalu-ation of prevalence of IEl-specific CTLs显示文摘 | Gyulai Z Endresz V Burian K | 2000 | J Infect Dis2000，181，5： | 1 |
| 17 | A canarypox vector-expressing cytomegalovirus ( VMV ) phosphoprotein 65 induces long lasting cytotoxic T cell responses in human CMV-seronegative subjects显示文摘 | Berencsi K Gyulai Z Gonczol E | 2001 | J Infect Dis2001，183，8： | 1 |
| 18 | Effects of the neuropeptides substance P,ealcitonin gene-related peptide and α-melanocyte-stimulating hormone on the IL-8/IL-8 receptor system in a caltured human keratinocyte cell line and dermal fibroblasts显示文摘 | Kiss M Kemeny L Gyulai R | 1995 | Inflammation1995，23，： | 1 |
| 19 | Dysfunctional blood and target tissue CD4^+ CD25^high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation 显示文摘 | Suigiyama H Gyulai R Toichi E | 2005 | Immunol2005，174，1： | 1 |
| 20 | Effect of whole body vibration applied on upper extremity muscles显示文摘 | Gyulai G Rhcz L Di Giminiani R | 2013 | Acta Physiologica Hungarica2013，100，1： | 1 |
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