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324篇 您的检索式：作者名="Guzman C"

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	题名	作者	年代	出处	被引量
1	Stem cell treatment and cerebral palsy: Systemic review and meta-analysis显示文摘BACKGROUND Perinatal complications may result in life-long morbidities,among which cerebral palsy(CP)is the most severe motor disability.Once developed,CP is a nonprogressive disease with a prevalence of 1-2 per 1000 live births in developed countries.It demands an extensive and multidisciplinary care.Therefore,it is a challenge for our health system and a burden for patients and their families.Recently,stem cell therapy emerged as a promising treatment option and raised hope in patients and their families.AIM The aim is to evaluate the efficacy and safety of stem cell treatment in children with CP using a systematic review and meta-analysis METHODS We performed a systematic literature search on PubMed and EMBASE to find randomized controlled clinical trials(RCT)investigating the effect of stem cell transplantation in children with CP.After the review,we performed a randomeffects meta-analysis focusing on the change in gross motor function,which was quantified using the gross motor function measure.We calculated the pooled standardized mean differences of the 6-and/or 12-mo-outcome by the method of Cohen.We quantified the heterogeneity using the I-squared measure.RESULTS We identified a total of 8 RCT for a qualitative review.From the initially selected trials,5 met the criteria and were included in the meta-analysis.Patients’population ranged from 0.5 up to 35 years(n=282).We detected a significant improvement in the gross motor function with a pooled standard mean difference of 0.95(95%confidence interval:0.13-1.76)favoring the stem cell group and a high heterogeneity(I2=90.1%).Serious adverse events were rare and equally distributed among both intervention and control groups.CONCLUSION Stem cell therapy for CP compared with symptomatic standard care only,shows a significant positive effect on the gross motor function,although the magnitude of the improvement is limited.Short-term safety is present and further highquality RCTs are needed.	Simone Eggenberger Céline Boucard Andreina Schoeberlein Raphael Guzman Andreas Limacher Daniel Surbek Martin Mueller	2019	World Journal of Stem Cells2019，11，10：	8
2	Noggin显示文摘	Krause C Guzman A Knaus P	2011	Int J Biochem Cell Biol2011，43，4：	1
3	Preferential induction of apoptosis for primary human leukemic stem cells显示文摘	GUZMAN M L SWIDERSKI C F HOWARD D S	2002	Proc Natl Acad Sci USA2002，99，16：	1
4	Malignant hypertension and hypertensive emergencies显示文摘	KITIYAKARA C GUZMAN N J	1998	J Am Soc Nephrol1998，9，1：	1
5	Antimicrobial peptides : promising compounds against pathogenic microorganisms显示文摘	Cruz J Ortiz C Guzman F	2014	Current Medici- nal Chemistry2014，21，20：	1
6	Treatment of dis- placed calcaneusfractures using a minimally invasive sinus tarsi approach 显示文摘	HOSPODAR P GUZMAN C JOHNSON P	2008	Orthopedics2008，31，11：	1
7	Optimal feedforward compensators for systems with right-half plane zeros显示文摘	RODRIGUEZ C GUZMAN J L BERENGUEL M HAGGLUND T	2014	)ournal of Process Control2014，24，4：	1
8	Protein kinase C regulates rod photoreceptor differentiation through modulation of stat3 signaling显示文摘	Pinzon - Guzman C Shaomin Zhang S Barnstable CJ	2010	Adv ExP Med Biol2010，664，：	1
9	Supercritical Extraction of Volatile Organic Components from Polyethylene Pellets显示文摘	CRISTANCHO D E GUZMAN J D TAYLOR C	2012	J of Supercritical Fluids2012，69，2012：	1
10	Gas particle flows about a cobra probe with purging显示文摘	Guzman M M Fletcher C A J Behnia M	1995	Computers & Fluids1995，24，1：	1
11	Clear cell sarco-ma: an institutional review显示文摘	Jacobs I A Chang C K Guzman G Salti G I	2004	Am Surg2004，70，：	1
12	Prognostic value of cytosolic P53 protein in breast cancer显示文摘	Montero S Guzman C Vargas C	2001	Tumour Biol2001，22，5：	1
13	Spinal neurenteric cyst presenting in infancy with chronic fever and acute myelopathy显示文摘	Kadhim H Guzman Proano P Saint Martin C	2000	Neurology2000，54，：	1
14	Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data显示文摘	HASSANE D C GUZMAN M L CORBETT C	2008	Blood2008，111，12：	1
15	Prognostic value of cytosolic P53 protein in breast cancer显示文摘	Montero S Guzman C Vargas C	2001	Tumor Biol2001，22，5：	1
16	Cancer stem cells显示文摘	Jordan C T Guzman M L Noble M	2006	N Engl J Med2006，355，12：	1
17	Contamination of coral reefs by heavy metals along the Caribbean coast of Central America(Costa Rica and Panama) 显示文摘	Guzman H Jimenez C	1992	Marine Pollution Bulletin1992，24，：	1
18	Prognostic value of cytosolic p53 protein in breast cancer显示文摘	Montero S Guzman C Vargas C		0，，05：	1
19	Eye Lens Structure of the Octopus Enteroctopus megalocyathus:Evidence of Growth显示文摘	CáRDENAS E R B CORREA S M GUZMAN R C	2011	Journal of Shellfish Research2011，30，2：	1
20	Prognostic value of cytosolic P53 protein in breast cancer显示文摘	Montero S Guzman C Vargas C	2001	rumor Biol2001，22，5：	1

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