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24篇 您的检索式：作者名="Gutierrez JS"

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	题名	作者	年代	出处	被引量
1	Intratumoral dendritic cell vaccin ation elicits potent tumoricidal im munity against malignant glioma in rats显示文摘Dendritic cells(DC)are attractive candidates for innovative cancer immunotherapy by virtu e of their ability to function as powe rful antigen presenting cells and elicit potent antitumor cytotoxic immune r esponses.With the aim of generating antitumor immunity,the authors sought to enhance in vivo tum or antigen presentation by using an i ntratumoral DC vaccination strateg y in the setting of partially irradiated intracranial brain tumo rs.Fisher rats,implanted with 9L gliomas in the right corpus striatum,w ere treated with freshly cultured,unpulsed syngeneic DC inoculated directly into the tumor bed.Intracranially inoculated DCs were found to drain to ipsilateral deep cervical lymph nodes.This was a ssociated with increased local and s ystemic antitumor cytoxicity,as evidenced by robust infiltration of treated tumors with CD4and CD8T ce lls as well as by increased IFN-gamma protein and message levels in in vitr o restimulated splenic lymphocytes.DC therapy resulted in prolonged survival and immunity to s ubsequent intracranial tumor re-ch allenge.These results demonstrate the viability of intratumoral DC vaccination as an effectiv e therapeutic strategy for intracra nial glioma.	Ehtesham M Kabos P Gutierrez MA Samoto K Black KL Yu JS	2003	癌症2003，22，7：	8
2	HES1 cooperates with pRb to activate RUNX2-dependent transcription 显示文摘	Lee JS Thomas DM Gutierrez G	2006	J Bone Miner Res2006，21，6：	1
3	Development and validationof a prognostic nomogram for recurrence - free survival after com-plete surgical resection of localised primary gastroinestinal stromaltumour:a retrospective analysis显示文摘	Gold JS Gonen M Gutierrez A	2009	Lancet Oncol2009，10，11：	1
4	Disruption of IRS -2 causes type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H	1998	Nature1998，391，6670：	1
5	Quantification of major lipid classes in human triacylglycerot rich lipoproteins by high - performance liquid chromatography with evaporative light scattering detection显示文摘	Perona JS Ruiz - Gutierrez V	2004	J Sep Sci2004，27，9：	1
6	Disruption of IRS-2 causes type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H	1998	Nature1998，391，：	1
7	Disrupition of IRS2 causes type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H		0，，：	1
8	HES1 coop- erates with pRb to activate RUNX2 - dependent transcription显示文摘	Lee JS Thomas DM Gutierrez G	2006	J Bone Miner Res2006，21，6：	1
9	Disruption of IRS -2 causes type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H Burks DJ	1998	Nature1998，，391：	1
10	Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour:a retrospective analysis显示文摘	Gold JS Gonen M Gutierrez A	2009	Lancet Oncol2009，10，：	1
11	Comparative effects of L-tryptophan and 1-methyl-tryptophan on immunoregulation induced by sperm, human pre-implantation embryo and trophoblast supematants显示文摘	Gutierrez G Fitzgerald JS Pohlmann T	2003	Am J Repred Immunol2003，50，4：	1
12	Disruption of IRS-2 cause type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H	1998	Nature1998，391，：	1
13	Reconstitution of Runx2/ Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation显示文摘	Bae JS Gutierrez S Narla R		0，，：	1
14	Development and validation of a prognostic nomogram for recurrence--free survival after complete surgical resection of Iocalised primary gastrointestinal stromal tumour:a retrospective analysis显示文摘	Gold JS Gonen M Gutierrez A	2009	Lancet Oncol2009，10，11：	1
15	Disruption of IRS-2 causes type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H	1998	Nature1998，391，6670：	1
16	Disruption of IRS-2 causes type 2 diabetes in mice显示文摘	Withers DJ Gutierrez JS Towery H	1998	Nature1998，391，6670：	1
17	Reconstitution of Runx 2/Cbf- al-null cells identifies a requirement for BMP-2 signaling thro- ugh a Runx 2 functional domain during osteoblast different- iation显示文摘	Bae JS Gutierrez S Narla R et ol	2007	J Cell Biochem2007，100，2：	1
18	Reconstitution of Runx2/ Cbfal- null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation显示文摘	Bae JS Gutierrez S Nada R	2007	J Cell Biochem2007，100，2：	1
19	Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation显示文摘	Bae JS Gutierrez S Narla R	2007	J Cell Biochem2007，100，2：	1
20	Disruption of IRS-2 eanses type 2 diabetes in mieem 显示文摘	Withers DJ Gutierrez JS Towery H	1998	Nature1998，391，6670：	1

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