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| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | Gastric cancer: Epidemiology, risk factors and prevention strategies显示文摘Gastric cancer(GC) is a global health problem, with more than 1 million people newly diagnosed with GC worldwide each year. GC is more prevalent in less developed countries than in more developed countries. About half of all GC cases worldwide occur in East Asia, notably China. Globally, overall incidence rates of GC are declining, which is potentially attributed to a decrease in Helicobacter pylori(H. pylori) infection and the use of refrigeration to preserve foods rather than salt. GC is a multifactorial disease, and its occurrence and development were impacted by environmental and genetic factors. H. pylori infection is the primary risk factor for GC, especially for non-cardia. The prognosis of GC is poor due to stages at the first diagnosis. The 5-year survival rate is less than 10% when patients are diagnosed at an advanced stage, but the rate is as high as 85% if patients are detected at an earlier stage. Endoscopic screening can potentially prevent GC by early diagnosis and early treatment and has been widely adopted in screening programs in East Asian countries, such as Japan and Korea. This review summarizes updated epidemiological aspects, risk factors, and prevention strategies of GC in recent years to help researchers determine the most effective intervention strategies for reducing risk of GC. | Lei Yang Xiangji Ying Shuo Liu Guoqing Lyu Zekuan Xu Xi Zhang Huichao Li Qingyu Li Ning Wang Jiafu Ji | 2020 | Chinese Journal of Cancer Research2020，32，6： | 52 |
| 3 | Lakes' state and abundance across the Tibetan Plateau显示文摘Understanding the changes in number and areal extent of lakes,as well as their abundance and size distribution is important for assessments of regional and global water resources,biogeochemical cycles,and changes in climate.In this study,changes in lake area greater than 1 km2are mapped using Landsat datasets,spanning the 1970s,1990,2000,and 2010.In addition,high-resolution images(GeoCover Landsat mosaic 2000,with a pixel size of 14.25 m)are used for the first time to map lakes as small as 0.001 km2across the entire Tibetan Plateau(TP).Results show that the numbers and areal extent of individual lakes[1 km2in size show a slight decrease between the 1970s and 1990,followed by a clear increase from 1990 to 2010.Ninety-nine new lakes are identified between the 1970s and 2010,71 of which are found between 1990 and 2010.This indicates the accelerated glacier melt and/or increased difference of precipitation minus evaporation since the 1990s.More than 80%of the lakes show an increase in their area between the 1970s and2010.The lake census,using 2000 imagery,shows that there are 32,843 lakes with a total area of 43,151.08±411.49 km2,which makes up 1.4%of the total area of the TP.Around 96%of all lakes are small,with an area\1 km2,while the 1,204 large lakes([1 km2)account for96%of the total lake area.The TP is subdivided into 12greater drainage basins,and of these the inner TP dominates in terms of the number of lakes(55.03%),the total area of lakes(66%),and lake density(0.026/km2compared to the mean,0.011/km2).A plot of lake abundance against size shows that the size distribution of lakes departs from a typical power-law distribution,but displays such a distribution at the mean elevation(4,715 m),with an r2value of 0.97 and a slope of-0.66.The slopes of the abundance-size equations from each of the 12 greater basins,and from all basins together,are larger than-1,supporting the inference that larger lakes,rather than the small lakes,contribute more to the total lake surface area across the TP.The lake inventory provided in this study,along with the assessment of lake size distribution,have important implications for estimates of water balance,for water resource management,and for lake area estimations in the TP. | Guoqing Zhang Tong Yao Hongjie Xie Kexiang Zhang Fujing Zhu | 2014 | Chinese Science Bulletin2014，59，24： | 33 |
| 4 | Friction stir welding of high-strength aerospace aluminum alloy and application in rocket tank manufacturing显示文摘Friction stir welding(FSW) has been widely adopted in aerospace industry for fabricating high-strength aluminum alloy structures, such as large volume fuel tanks, due to its exceptional advantages including low distortion, less defects and high mechanical properties of the joint. This article systematically reviews the key technical issues in producing large capacity aluminum alloy fuel tanks by using FSW,including tool design, FSW process optimization, nondestructive testing(NDT) techniques and defect repairing techniques, etc. To fulfill the requirements of Chinese aerospace industry, constant-force FSW,retractable tool FSW, lock joint FSW, on-line NDT and solid-state equal-strength FSW techniques, as well as a complete set of aerospace aluminum FSW equipment, have been successfully developed. All these techniques have been engineered and validated in rocket tanks, which enormously improved the fabrication ability of Chinese aerospace industry. | Guoqing Wang Yanhua Zhao Yunfei Hao | 2018 | Journal of Materials Science & Technology2018，34，1： | 33 |
| 5 | A robust but variable lake expansion on the Tibetan Plateau显示文摘Lakes on the Tibetan Plateau(TP)are an indicator and sentinel of climatic changes[1].We extended lake area changes on the TP from 2010[2]to 2018,and provided a long and dense lake observations between the 1970s and 2018.We found that the number of lakes,with area larger than 1 km2,has in creased to?1,400 in 2018 from?1,000 in the 1970s.The total area of these lakes decreased between the 1970s and?1995,and then showed a robust increase,with the exception of a slight decrease in 2015.This expansion of the lakes on the highest plateau in rhe world is a response to a hydrological cycle intensified by recent climate changes[3]. | Guoqing Zhang Wei Luo Wenfeng Chen Guoxiong Zheng | 2019 | Science Bulletin2019，64，18： | 30 |
| 6 | Zircon SHRIMP U-Pb geochronology of the Neoproterozoic Chengjiang Formation in central Yunnan Province(SW China) and its geological significance显示文摘The Chengjiang Formation is the earliest continental clastic deposit after the Jinning Orogeny in central Yunnan Province,and therefore its accurate depositional age is significant for understanding the formation and evolution of the Neoproterozoic rift basins in southern China.However,hampered by accuracy of the dating technique,the existing age data for the Chengjiang Formation are not very reliable.A large number of magmatic zircons were obtained from the tuff interbed in the lower part of the Chengjiang Formation in Jinyang area and the bottom part of the Chengjiang Formation in Dongchuan area,central Yunnan Province,and high-precision SHRIMP U-Pb dating was carried out on these zircons.The results show that the weighted mean 206 Pb/238 U ages are 797.8±8.2 and 803.1±8.7 Ma respectively.In combination with related geological evidence,it has been demonstrated that the bottom boundary age of the Chengjiang Formation should be 800±5 Ma,whereas the top boundary age could be ca 725 Ma.By synthetically analyzing the latest age data for the relevant strata,it has been confirmed that the Chengjiang Formation should be correlated with the Suxiong Formation and the Kaijianqiao Formation in western Sichuan Province,the Liantuo Formation in the middle and lower Yangtze,the Hongchicun Formation and the Shangshu Formation in northern Zhejiang Province,the Puling Formation in southern Anhui Province,the Luokedong Formation and the Majianqiao Formation in northwestern Jiangxi Province,the Wuqiangxi Formation in northwestern Hunan Province,the Fanzhao Formation and the Qingshuijiang Formation in southeastern Guizhou Province,and the Sanmenjie Formation and the Gongdong Formation in northern Guangxi Province.Sedimentary cycle analysis shows that the sedimentary filling sequence of the Neoproterozoic rift basins in southern China can be divided into four cycles.Among them,Cycle II began at ca.800 Ma,accompanied by intensive tectonic-thermal events.The zircon U-Pb ages from the bottom of the Chengjiang Formation reported in this paper indicate that the Neoproterozoic Kangdian rift subbasin probably started to develop at ca.800 Ma and therefore missed Cycle I of the Neoproterozoic sedimentary filling sequence in southern China. | JIANG XinSheng WANG Jian CUI XiaoZhuang ZHUO JieWen XIONG GuoQing LU JunZe LIU JianHui | 2012 | Science China Earth Sciences2012，55，11： | 25 |
| 7 | Water balance estimates of ten greatest lakes in China using ICESat and Landsat data显示文摘湖水平和区域变化对地区性的气候变化敏感并且能被用来间接地估计湖的水平衡。在这研究,在中国的 10 个最大的湖, 1000 km2 或更大,被检验在从在 2003 和 2009 之间记录的 ICESat 和 Landsat 数据分别地导出的湖水平和区域决定变化。湖水平和在西藏的高原( TP )和在东北中国的克辛凯·莱克的 Selin 公司, Nam 公司,和金海·莱克的区域的时间系列展出一个增加的趋势与在湖水平( 0.69 m/a )显示出最快的上升的 Selin 公司,区域( 32.59 km2/a ),和在 10 之中的体积( 1.25 km3/a )检验了湖。在北中国的干旱、半干旱的区域的 Bosten 和 Hulun 湖在湖水平和区域显示出衰落,与显示出在湖水平(0.43 m/a ) 和显示出最大的区域收缩(35.56 km2/a ) 的胡伦·莱克的最大的减少的博斯顿·莱克一起。然而,没有任何明显的趋势,在长江盆的中间降低活动范围的 Dongting, Poyang, Taihu,和 Hongze 湖介绍季节的可变性。湖水平和区域为 Selin 公司, Nam 公司, Qinghai, Poyang, Hulun,和 Bosten 湖显示出强壮的关联(R 2 > 0.80 ) 并且为 Taihu, Hongze,和 Xingkai 湖和为东方东廷·莱克(0.37 ) 的弱关联(0.70 ) 。湖水平变化和水体积变化在为所有湖的很好的同意(R 2 > 0.98 ) 。10 个湖的水平衡根据湖水平和区域变化被导出,与分别地显示出 9.08, 4.07, 2.88,和 1.09 km3 的积极的水预算的 Selin 公司, Nam 公司, Qinghai,和 Xingkai 湖。分别地, Bosten 和 Hulun 湖显示出 3.01 和 4.73 km3 的否定预算,沿着长江的四个湖不显示出明显的变化。对在这四个湖的湖水平和区域变化的可能的解释也被讨论。这研究建议遥感能为估计湖水平衡作为一个快、有效的工具服务的那颗卫星。 | ZHANG GuoQing XIE HongJie YAO TanDong KANG ShiChang | 2013 | Chinese Science Bulletin2013，58，31： | 25 |
| 8 | The effects of land consolidation on the ecological connectivity based on ecosystem service value: A case study of Da'an land consolidation project in Jilin province显示文摘Land consolidation has a profound impact on landscape patterns and ecological functions at various scales through engineering and biological measures. In recent years, China invests more than 100 billion RMB yuan on land consolidation each year. To understand how land consolidation affects landscape patterns and ecosystems, we investigated the ecosystem service value and the ecological connectivity in a consolidated area of Da'an city from 2008 to 2014 using a revised ecological connectivity index. The results indicated that land consolidation has certain negative influences on the ecosystem services in this area. The total ecosystem service value will decrease by nearly 30% in the late stage of consolidation. This decrease is caused by the loss of ecosystem service of the wetland and grassland, despite a sensible increase of cultivated land. In addition, land consolidation could change the ecological connectivity as well as the land use structure. Up to 85% of the entire area will be in low connectivity in the late stage of consolidation, representing a 6.23% increase in the total coverage compared to pre-consolidation. Finally, the different connectivity landscape and their key areas can be identified by the revised ecological connectivity index effectively. This study is helpful to trace out the relationships between landscape pattern and ecological process, and provides insights for ecological planning and designing of land consolidation in this area. We suggest that more attentions should be paid to improve the quality and ecosystem service value per unit area of the landscape, to establish ecological compensation mechanism of wetland losses, and to create the ecological corridors along the least accumulated impendence surface in the key areas during land consolidation. | WANG Jun YAN Shenchun GUO Yiqiang LI Junran SUN Guoqing | 2015 | Journal of Geographical Sciences2015，25，5： | 26 |
| 9 | Mapping of a new gene for brown planthopper resistance in cultivated rice introgressed from Oryza eichingeri显示文摘Wild rice species is an important source of useful genes for cultivated rice improvement Some accessions of Oryza eichingeri (In = 24, CC) from Africa confer strong resistance to brown planthopper (BPH), whitebacked planthopper (WBPH) and bacterial blight (KB). In the present study, restriction fragments length polymorphism (RFLP) and simple sequence repeats (SSR) analysis were performed on disomic backcross plants between Oryza saliva (2n =24, AA) and O. eichingeri in order to identify the presence of O, eichingeri segments and further to localize BPH-resistant gene. In the introgression lines, 1-6 O. eichingeri segments were detected on rice chromosomes 1, 2, 6, or/and 10. The dominant BPH resistant gene, tentatively named Bphl3(t), was mapped to chromosome 2, being 6.1 and 5.5 cM away from two microsatellite markers RM240 and RM250, respectively. The transfer and localization of this gene from O. eichingeri will contribute to the improvement of BPH resistance in cultivated rice. | LIU Guoqing YAN Huihuang FU Qiang QIAN Qian ZHANG Zhitao ZHAI Wenxue ZHU Lihuang | 2001 | Chinese Science Bulletin2001，46，17： | 24 |
| 10 | Potentially dangerous glacial lakes across the Tibetan Plateau revealed using a large-scale automated assessment approach显示文摘Glacial lake outburst floods(GLOFs) are a major concern in the Himalaya and on the Tibetan Plateau(TP),where several disasters occurring over the past century have caused significant loss of life and damage to infrastructure. This study responds directly to the needs of local authorities to provide guidance on the most dangerous glacial lakes across TP where local monitoring and other risk reduction strategies can subsequently be targeted. Specifically, the study aims to establish a first comprehensive prioritisation ranking of lake danger for TP, considering both the likelihood and possible magnitude of any outburst event(hazard), and the exposure of downstream communities. A composite inventory of 1,291 glacial lakes(>0.1 km^2) was derived from recent remote sensing studies, and a fully automated and object assessment scheme was implemented using customised GIS tools. Based on four core determinates of GLOF hazard(lake size, watershed area, topographic potential for ice/rock avalanching, and dam steepness), the scheme accurately distinguishes the high to very high hazard level of 19 out of 20 lakes that have previously generated GLOFs. Notably, 16% of all glacial lakes threaten human settlements, with a hotspot of GLOF danger identified in the central Himalayan counties of Jilong, Nyalam, and Dingri, where the potential trans-boundary threat to communities located downstream in Nepal is also recognised. The results provide an important and object scientific basis for decision-making, and the methodological approach is ideally suited for replication across other mountainous regions where such first-order studies are lacking. | Simon Keith Allen Guoqing Zhang Weicai Wang TANDong Yao Tobias Bolch | 2019 | Science Bulletin2019，64，7： | 20 |
| 11 | 地形对大光斑激光雷达森林回波影响研究显示文摘利用三维激光雷达森林回波波形模型模拟了地形对波形的影响,并用ICEsat GLAS的数据对模拟结果进行了验证。结果表明坡度对大光斑激光雷达波形影响较大,随着坡度的增大,地面回波和树冠回波都展宽,波形长度也随之增加,同时地面的波峰和植被的波峰值都降低,来自地面的回波明显减少,并逐渐与靠近地面的回波发生信息混叠。鉴于二者的关系呈近似线性正相关,在实际的森林参数反演中可望通过减去一个含有坡度或地形起伏度的因子进行地形效应纠正。 | 庞勇 李增元 Sun Guoqing Michael Lefsky 车学俭 陈尔学 | 2007 | 林业科学研究2007，20，4： | 19 |
| 12 | Three-dimensional Finite Element Analysis of the Mechanical Properties of Helical Thread Connection显示文摘Conventional analytical and numerical methods for the mechanical properties of helical threads are relied on many assumptions and approximations and thus hardly yield satisfied results. A parameterized 3D finite element model of bolted joints with real helical thread geometry is established and meshed with refined hexahedral elements. The Von Mises plasticity criterion, kinematic hardening rule of materials and interfacial contacts are employed to make it possible for the suggested model be able to approach real assembly conditions. Then, the mechanical properties of bolted joints with different thread pitches, thread numbers and modular ratios are investigated, including the contact pressure distribution at joint interfaces, the axial load distribution and stress concentration in screw threads during the loading and unloading process. Simulation results indicate that the load distribution in screw threads produced by the suggested model agrees well the results from CHEN's photoelastic tests. In addition, an interesting phenomenon is found that tightening the bolt with a large preload first and then adjusting the clamping force by unloading can make the load distribution more uniform and reduce the maximum residual equivalent stress in thread roots by up to 40%. This research provides a simple and practical approach to constructing the 3D finite element model and predicting the mechanical properties of helical thread connection. | YANG Guoqing HONG Jun ZHU Linbo LI Baotong XIONG Meihua WANG Fei | 2013 | Chinese Journal of Mechanical Engineering2013，26，3： | 19 |
| 13 | Celastrus orbiculatus extract induces mitochondrial-mediated apoptosis in human hepatocellular carcinoma cells显示文摘OBJECTIVE:To investigate the apoptotic effects and underlying molecular mechanisms of Celastrus orbiculatus(C.orbiculatus) extract in human hepatocellular carcinoma cells.METHODS:Human hepatocellular carcinoma cells(HCCLM6) were treated with C.orbiculatus extract(COE) at different nontoxic concentrations(10,20,40,80,and 160 μg/mL).The effect of COE on HC-CLM6 viability was examined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assays.Cellular apoptosis following COE treatment was assessed by flow cytometry and western blot analysis.RESULTS:COE significantly inhibited cell viability and induced apoptosis of HCCLM6 cells in a dose-dependent manner.Apoptosis was accompanied by increased Bax expression and decreased Bcl-2 expression.In addition,COE treatment led to the release of cytochrome c,activation of caspase-3,and cleavage of poly(ADP-ribose) polymerase(PARP).Furthermore,activation of extracellular signal-regulated kinase(ERK),p38 kinase,and c-Jun N-terminal kinase(JNK) phosphorylation,and down-regulation of Akt phosphorylation was observed.CONCLUSION:COE induces mitochondrial-mediated,caspase-dependent apoptosis in HCCLM6 cells,which might be attributed to the activation of mitogen-activated protein kinase(MAPK) and inhibition of Akt signaling pathways.These data suggest that COE may be a potential treatment for human hepatocellular carcinoma. | Hua Zhang Yayun Qian Yanqing Liu Guoqing Li Pingfang Cui Yaodong Zhu Hui Ma Xue Ji Shiyu Guo Hisamits Tadashi | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 18 |
| 14 | High-density circulating fluidized bed gasifier for advanced IGCC/IGFC-Advantages and challenges显示文摘Coal-fired Integrated Gasification Combined Cycle(IGCC)and Integrated coal Gasification Fuel-cell Combined cycle(IGFC)are being developed as high-efficiency electric power generation technology.However,the highest theoretical gross thermal efficiency of the conventional IGCC/IGFC is still below 52%.In order to obtain higher power generation efficiency,an advanced IGCC(A-IGCC)or advanced IGFC(A-IGFC)system making use of the exergy recuperation concept by recycling waste heat from gas turbine or fuel cells for steam gasification of coal and biomass was proposed in our laboratory.Corresponding to this system,a novel high-density triple-bed combined circulating fluidized bed(TBCFB)gasifier,composed of a downer pyrolyzer,a bubbling fluidized bed char gasifier,and a riser combustor,was proposed to replace traditional gasifiers such as the entrained flow bed gasifier.The new system is expected to more effectively utilize the waste heat from gas turbines or fuel cells and the heat produced by the combustion of the unreacted char in the riser combustor for pyrolysis and gasification of coal and biomass.In this short review,the advantages and future challenges in the development of high-density TBCFB gasifier are presented and discussed. | Guoqing Guan Chihiro Fushimi Atsushi Tsutsumi Masanori Ishizuka Satoru Matsuda Hiroyuki Hatano Yoshizo Suzuki | 2010 | Particuology2010，8，6： | 17 |
| 15 | Nanocellulose:Extraction and application显示文摘Recently,nanocellulose and its applications gain high attraction in both research and industrial areas due to its attractive properties such as excellent mechanical properties,high surface area,rich hydroxyl groups for modification,and natural properties with 100%environmental friendliness.In this review,the background of nanocellulose originated from lignocellulosic biomass and the typical extraction methods and general applications are summarized,in which the nanocellulose extraction methods related to ball milling are mainly introduced.Also,an outlook on its future is given.It is expected to provide guidance on the effective extraction of nanocellulose from biomass and its most possible applications in the future. | Patchiya Phanthong Prasert Reubroycharoen Xiaogang Hao Guangwen Xu Abuliti Abudula Guoqing Guan | 2018 | Carbon Resources Conversion2018，1，1： | 17 |
| 16 | Volume change behavior of unsaturated soils under non-isothermal conditions显示文摘With the development of modern geotechnical engineering practices such as the construction of high level radioactive waste repositories, exploitation and utilization of geothermal resources, energy-saving buildings and underground storage of CO 2 , research into the influence of temperature on the basic mechanical properties of unsaturated soils has become an important issue internationally. By using the work expression and considering the influence of temperature on the basic properties of unsaturated soils, the average soil skeleton stress, modified suction and temperature were selected as state variables of generalized forces in thermodynamics and the soil skeleton strain, saturation and entropy were chosen as state variables of generalized flows conjugate to the variables of generalized forces. Based on the nonlinear multi-field coupled model and by using existing experimental results, an elastic-plastic constitutive model of unsaturated soils under non-isothermal conditions was developed to analyze the influence of temperature on the deformation properties of unsaturated soils. The model was used to predict and analyze the influence of suction and temperature on the deformation properties of unsaturated soils under isotropic conditions, and was successfully verified using experimental results. | CAI GuoQing ZHAO ChengGang LIU Yan LI Jian | 2011 | Chinese Science Bulletin2011，56，23： | 16 |
| 17 | Intelligent control of mode-locked femtosecond pulses by time-stretch-assisted real-time spectral analysis显示文摘Mode-locked fiber lasers based on nonlinear polarization evolution can generate femtosecond pulses with different pulse widths and rich spectral distributions for versatile applications through polarization tuning.However,a precise and repeatable location of a specific pulsation regime is extremely challenging.Here,by using fast spectral analysis based on a time-stretched dispersion Fourier transform as the spectral discrimination criterion,along with an intelligent polarization search algorithm,for the first time,we achieved real-time control of the spectral width and shape of mode-locked femtosecond pulses;the spectral width can be tuned from 10 to 40 nm with a resolution of ~1.47 nm,and the spectral shape can be programmed to be hyperbolic secant or triangular.Furthermore,we reveal the complex,repeatable transition dynamics of the spectrum broadening of femtosecond pulses,including five middle phases,which provides deep insight into ultrashort pulse formation that cannot be observed with traditional mode-locked lasers. | Guoqing Pu Lilin Yi Li Zhang Chao Luo Zhaohui Li Weisheng Hu | 2020 | Light(Science & Applications)2020，9，1： | 16 |
| 18 | A nonlinear multi-field coupled model for soils显示文摘A nonlinear multi-field coupled model for multi-constituent three-phase soils is derived by using the hybrid mixture theory. The balance equations with three levels (constituents, phases and the whole mixture soil) are set up under the assumption that soil is composed of multi-constituent elastic-plastic solid skeleton (which is different from the linearization method) and viscous liquid and ideal gas. With reasonable constitutive assumptions in such restrictive conditions as the principles of determinism, equipresence, material frame-indifference and the compatible principle in continuum mechanics, a theoretical framework of constitutive relations modeling three-phase soil in both non-equilibrium and equilibrium states is established, thus the closed field equations are formed. In the theoretical framework, the concept of effective generalized thermodynamic forces is introduced, and the nonlinear coupling constitutive relations between generalized dissipation forces and generalized flows within the system at nonequilibrium state are also presented. On such a basis, four special coupling relations, i.e., solid thermal elastic-plastic constitutive relation, liquid visco-elastic-plastic constitutive relation, the generalized Fourier’s law, and the generalized Darcy’s law are put forward. The generalized or nonlinear results mentioned above can degenerate into the linear coupling results given by Bennethum and Singh. Based on a specific dissipation function, the concrete form of generalized Darcy’s law is deduced, which may degenerate into the traditional form of Darcy’s law by neglecting the influence of skeleton deformation and temperature. Without considering temperature and other coupling effects, the nonlinear coupled model in this paper can degenerate into a soil elastic-plastic constitutive model. | CAI GuoQing ZHAO ChengGang LIU Yan LI Jian | 2011 | Science China(Technological Sciences)2011，54，5： | 15 |
| 19 | A finite element modeling of posterior atlantoaxial fixation and biomechanical analysis of C2 intralaminar screw fixation显示文摘 | Ma Xuexiao Peng Xianbo Xiang Hongfei Zhang Yan Zhang Guoqing Chen Bohua | 2014 | Chinese Medical Journal2014，，7： | 15 |
| 20 | Epidemic Update and Risk Assessment of 2019 Novel Coronavirus--China, January 28, 2020显示文摘On December 29,2019,the health authorities in Hubei Province and Wuhan City received a report of a cluster of pneumonia cases of unknown etiology from a local hospital,and all four patients were employees of the Wuhan Huanan Seafood Wholesale Market(HN market for short)(1).By January 8,2020,Chinese authorities had identified a new virus 2019 novel coronavirus(2019-nCoV)linked with the outbreak of disease,which has been named novel coronavirusinfected pneumonia(NCIP)(2).On 15 January,the National Health Commission(NHC)issued guidelines for the diagnosis,treatment,prevention,and control of NCIP.These guidelines directed case monitoring,reporting,diagnosis,treatment,management,close contact management,and laboratory testing. | Wenxiao Tu Houlin Tang Fangfang Chen Yinong Wei Tingling Xu Kaiju Liao Nijian Xiang Guoqing Shi Qun Li Zijian Feng | 2020 | China CDC weekly2020，2，6： | 15 |
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