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| 1 | Effects of folic acid on in vitro astrocytic differentiation of neural stem cells from neonatal rats显示文摘BACKGROUND:Folic acid is essential for normal functioning of the nervous system.Previous studies have focused on the effects of folic acid on astrocyte proliferation. OBJECTIVE:To explore the effects of folic acid on astrocyte differentiation of neural stem cells (NSCs) and the related mechanisms in vitro. DESIGN,TIME AND SETTING:A randomized,controlled,grouping experiment was performed in Tianjin Medical University between August 2007 and October 2008. MATERIALS:Folic acid and 5-bromo-2-deoxyuridine(BrdU) were obtained from Sigma,MO,USA. Primary antibodies[rabbit anti-rat nestin,β-tubulin-Ⅲ,glial fibrillary acidic protein,and neurogenin1 (Ngn1);mouse anti-rat BrdU andβ-actin monoclonal antibodies]were purchased from Santa Cruz Biotechnology,USA. METHODS:At 6 days of NSC proliferation from 24-hour-old neonatal rats,BrdU incorporation assay was performed.Seven days after primary culture,NSCs were induced to differentiate with medium containing 5%fetal bovine serum.Cultured NSCs were assigned to three groups:control,low-dose (liquid media with 8 mg/L folic acid),and high-dose folic acid(liquid media with 44 mg/L folic acid). MAIN OUTCOME MEASURES:At day 7 after primary culture,the cells were identified as NSCs by immunocytochemical methods.Double-label immunofluorescence technique for glial fibrillary acidic protein/BrdU detected differentiated cells 7 days after induction.Western blot was used to analyze expression of Ngn1 protein in NSCs. RESULTS:In serum-free suspension medium,neurospheres comprised a large number of Nestin-, glial fibrillary acidic protein-,β-tubulin-Ⅲ-,and BrdU-positive cells.Compared with the control group, high-dose folic acid supplementation led to an marked increase in the percentage of glial fibrillary acidic protein/BrdU-positive cells(P<0.05),and significantly decreased Ngn1 protein expression (P<0.05). CONCLUSION:Folic acid promotes astrocytic differentiation of NSCs,which might be related to downregulation of Ngn1 protein expression. | Xumei Zhang Guowei Huang Zhihong Tian Guanglei Wang Dalin Ren | 2009 | Neural Regeneration Research2009，4，8： | 4 |
| 2 | Efficient microwave absorption achieved through in situ construction of core-shell Co Fe_(2)O_(4)@mesoporous carbon hollow spheres显示文摘Cobalt ferrite(CoFe_(2)O_(4)),with good chemical stability and magnetic loss,can be used to prepare composites with a unique structure and high absorption.In this study,CoFe_(2)O_(4)@mesoporous carbon hollow spheres(MCHS)with a core-shell structure were prepared by introducing CoFe_(2)O_(4)magnetic particles into hollow mesoporous carbon through a simple in situ method.Then,the microwave absorption performance of the CoFe_(2)O_(4)@MCHS composites was investigated.Magnetic and dielectric losses can be effectively coordinated by constructing the porous structure and adjusting the ratio of MCHS and CoFe_(2)O_(4).Results show that the impedance matching and absorption properties of the Co Fe_(2)O_(4)@MCHS composites can be altered by tweaking the mass ratio of MCHS and CoFe_(2)O_(4).The minimum reflection loss of the Co Fe_(2)O_(4)@MCHS composites reaches-29.7 dB at 5.8 GHz.In addition,the effective absorption bandwidth is 3.7 GHz,with the thickness being 2.5 mm.The boosted microwave absorption can be ascribed to the porous core-shell structure and introduction of magnetic particles.The coordination between the microporous morphology and the core-shell structure is conducive to improving the attenuation coefficient and achieving good impedance matching.The porous core-shell structure provides large solid-void and CoFe_(2)O_(4)-C interfaces to induce interfacial polarization and extend the electromagnetic waves’multiple scattering and reflection.Furthermore,natural resonance,exchange resonance,and eddy current loss work together for the magnetic loss.This method provides a practical solution to prepare core-shell structure microwave absorbents. | Lianggui Ren Yiqun Wang Xin Zhang Qinchuan He Guanglei Wu | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，3： | 2 |
| 3 | Electrospun poly( vinyl alcohol)/glucose oxidase biocomposite membranes for biosensor applications 显示文摘 | Ren Guanglei Xu Xinhua Liu Qiang | 2006 | Reactive and Functional Polymers2006，66，12： | 1 |
| 4 | Electro- spun poly(vinyl alcohol)/glucose oxidase biocomposite mem- branes for biosensor applications显示文摘 | REN GUANGLEI XU XINHUA LIU QIANG | 2006 | Reactive and Functiolral Polymers2006，66，12： | 1 |
| 5 | Rational manipulation of composition and construction toward Zn/Co bimetal hybrids for electromagnetic wave absorption显示文摘Rational manipulation of multi-metal hybrids with controllable compositions and constructions is evolv-ing as an efficacious strategy for tunable electromagnetic(EM)characteristics and EM wave(EMW)ab-sorption.Herein,a novel bi-orientation etching approach is proposed to regulate the chemical composi-tions and hybridization construction of Zn/Co hybrids,thence meeting the synergistic interaction among diverse compositions for ultra-high EMW absorption.Attributing to the stepwise heterometallic modi-fication by Zn in Co-ZIFs(Zn@Co-ZIF)and Co in Zn-ZIFs(Co@Zn-ZIF),corresponding pyrolysis products with variable Zn/Co atomic concentration and hybridization states(Zn@Co-C,Co@Zn-C)can be obtained.The Co species was confirmed to have a positive impact on both the dielectric and magnetic response,while an appropriate amount of Zn hybridization in Co substance further enhanced the synergistic ef-fect between multiple loss mechanisms,promoting the minimum reflection loss and effective absorption bandwidth of Zn@Co-C reached-34.99 dB and 5.52 GHz(2.00 mm),respectively.Finally,this work re-veals the composition and construction dependency of bimetal hybrids on EMW absorption,which can be a strong reference for developing EMAs with diverse hybridization structures. | Xiuyun Ren Yihe Song Zhenguo Gao Yalan Wu Zirui Jia Guanglei Wu | 2023 | Journal of Materials Science & Technology2023，，3： | 1 |
| 6 | Electrospun poly(vinyl alcohol) / glucose oxidase biocomposite membranes for biosensor applications显示文摘 | Ren Guanglei Xu Xinhua Liu Qiang | 2006 | Reactive & Functional Polymers2006，66，： | 1 |
| 7 | Advanced Organic Materials for Nonmetallic Charge Carrier-Based Batteries显示文摘Organic electrode materials(OEMs),withmerits of structural diversity,molecular-level controllability,resource abundance,and environmental friendliness,have become a promising electrode candidate for low-carbon renewable batteries.Safer,environmentally benign,and sustainable aqueous rechargeable batteries are particularly appealing for large-scale energy storage applications.This review aims to provide an insightful discussion of OEMs in nonmetallic charge carrier-based batteries,especially for the application in aqueous rechargeable systems.The emerging application of OEMs in versatile aqueous batteries will be analyzed emphatically,including aqueous proton batteries,aqueous ammonium-ion batteries,and air self-charging batteries.We expect that this review can serve as a guide for the future development of OEMs in nonmetallic charge carrier-based batteries and provide inspiration for unmet challenges. | Tao Sun Guanglei Ren Qi Jie Wu Mao song Liu Qian Yang Xingwen Cheng Yuqiao Zhang Long Zhang Shun Li Weidong Shi Jianming Zhang | 2023 | Renewables2023，1，5： | 0 |
| 8 | Three-dimensional macroscopic absorbents: From synergistic effects to advanced multifunctionalities显示文摘The accelerated arriving of 5G era has brought a new round of intelligent transformation which will completely emancipate smart terminal devices.While the subsequent deleterious effect of electromagnetic wave on electronic devices is increasingly serious,driving the growth of next-generation electromagnetic wave absorbents.As a tactful combination of components and structures,three-dimensional(3D)macroscopic absorbents with fascinating synergy afford exceptional electromagnetic wave absorption,and tremendous efforts have been devoted to this investigation.However,in terms of macroscopic absorbents and their synergistic effect,few reviews are proposed to comb the latest achievements and detailed synergy.This review article focuses on the synergistic effect of macro-architectured absorbents mainly including structure-induced synergy,structure-components synergy,and multiple-components induced synergy.And then the potential construction principles and strategies of macroscopic absorbents are combed.Significantly,the key information for structures and components manipulation including nano-micro design and components regulation is further dissected by critically selected cutting-edge 3D macroscopic absorbents.Moreover,a brief summary of multifunctional electromagnetic wave absorbents(EWAs)-based macroscopic structures is presented.Finally,the development prospects and challenges of these materials are discussed. | Shijie Zhang Di Lan Xingliang Chen Yueyuan Gu Junwen Ren Suxuan Du Shichang Cai Xiaomiao Zhao Zhiwei Zhao Guanglei Wu | 2024 | Nano Research2024，17，3： | 0 |
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