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| 1 | Detection of tris-(2, 3-dibromopropyl) isocyanurate as a neuronal toxicant in environmental samples using neuronal toxicity-directed analysis显示文摘Neuronal toxic pollutants in environment possess hazards to human health. It is essential to determine the causative neuronal toxicants in environmental samples. In the present study, viability of primary cultured cerebellar granule neurons (CGNs), combined with sample extraction, chemical fractionation and identification, was applied for screening acid-resistant neuronal toxic substances in environmental samples. River sediments and agricultural soils along the river near a brominated flame retardant (BFR) manufacturing plant in South China were collected to screen the key neuronal toxicants. The results indicated that the manufacturing plant was a source of neuronal toxicity risks. In the sediment and soil near the plant, one of the causative toxicants was identified as tris-(2,3-dibromopropyl) isocyanurate (TBC) using HPLC-MS/MS. In addition, an unknown chemical possibly causing significant neuronal toxicity was isolated from all the soil samples in the region. | QU GuangBo SHI JianBo LI ZhuoNa RUAN Ting FU JianJie WANG Pu WANG Thanh JIANG GuiBin | 2011 | Science China Chemistry2011，54，10： | 3 |
| 2 | Polymorphisms of nucleotide-excision repair genes may contribute to sperm DNA fragmentation and male infertility显示文摘 | Aihua Gu Guixiang Ji Yong Zhou Yan Long Xiangguo Shi Guangbo Fu Shoulin Wang Ling Song Xinru Wang | 2010 | Reproductive BioMedicine Online2010，，5： | 1 |
| 3 | P53 codon 72 polymorphism and ovarian cancer risk:a meta-analysis显示文摘客观 p53 是肿瘤 suppressor 基因并且涉及卵巢的癌症的病原学。调查在 72 多型性和卵巢的癌症风险显示出冲突结果的 p53 codon 之间的协会的研究。我们从合格研究执行了这元分析评估这种声称的关系。这元分析从 9 盒子控制研究被执行的方法,包括 825 个卵巢的案例和 1073 控制。他修理了的 T 和随机的效果模型被用来为这多型性的各种各样的对比估计机会比率(ORs ) 。结果联合结果基于所有研究证明显著地减少的风险与变体职业人员 / 职业人员遗传型被联系,与 Arg/Pro+Arg/Arg 遗传型相比(或, 0.70;95%CI, 0.510.95 ) 。当成层时由种族的研究,我们发现有变体遗传型职业人员 / 职业人员的个人与 Arg/Arg 遗传型相比有卵巢的癌症的显著地减少的风险(或, 0.43;95%CI, 0.200.89 ) 并且 Arg/Pro+Arg/Arg 遗传型(或, 0.61;95%CI, 0.370.99 ) 在非洲人之中。结论这元分析建议 72 多型性可以贡献的 p53 codon 基因危险性到卵巢的癌症。更多的研究应该基于更大的样品尺寸被执行证实调查结果。 | Zhizhong Zhang Guangbo Fu Meilin Wang Na Tong Shizhi Wang Zhengdong Zhang | 2008 | Journal of Nanjing Medical University2008，22，5： | 1 |
| 4 | Ecological Characteristics of Soil Grown with Tricholoma Matsutake显示文摘A 5-year study on the soil ecological environment of matsutake (Trihcholoma Matsutake) growing areas near Changbai Mountains showed that several factors, such as climate, parent material, organism and landform, which form the soil ecosystem provided suitable ecological environment for the formation and growth of matsutake. How to improve the construction and function of the soil ecosystem in order to utilize the natural resource continuously was also studied. | XU GUANGBO FU WEIJIE WEI TIEZHENG LI GUIHUA LIANG YUNJIANG QUAN MINGDAO and YANG SHURONG(Yianbian Agricultural College, Longjing, Jinn 133400 (China)) | 1997 | Pedosphere1997，7，4： | 1 |
| 5 | 本校近期发表IF≥4.0的SCI论文摘要(英文)——Relation between Urinary Metabolites of Polycyclic Aromatic Hydrocarbons and Human Semen Quality显示文摘 | Xia Yankai Zhu Pengfei Wang Shoulin Gu Aihua Wang Li Lu Chuncheng Song Ling Wang Xinru Han Yan Fu Guangbo | 2009 | 南京医科大学学报(自然科学版)2009，29，9： | 1 |
| 6 | Research Progress on Artificial Cultivation of Trhicoloma Matsutake and Theory of the Shiro in Changbai Mountains显示文摘Study on artificial cultivation of Tricholoma matsutake carried through by the present research group in Changbai Mountains in recent years was briefly reviewed in the paper, and then, the signify-cance of cultivation, mechanism of formation, hiberar-chy, growth cycle and suitable living environment, were summarized. | Guangbo Xu Tiezheng Wei Weijie Fu Minjie Fu Yunjiang Liang | 2006 | Science Foundation in China2006，14，2： | 0 |
| 7 | 本校近期发表IF≥4.0的SCI论文摘要(英文)——Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population显示文摘 | Wang Meilin Wang Miaomiao Yuan Lin Zhang Zheng dong Zhang Wei Fu Guangbo Wei Qingyi | 2009 | 南京医科大学学报(自然科学版)2009，29，9： | 0 |
| 8 | CASP8 promoter polymorphism,mRNA expression and risk of prostate cancer among Chinese men显示文摘Caspase-8 (CASP8) plays a key role in apoptosis.We examined by genotyping whether the-652 six-nucleotide insertion-deletion (6N ins/del) polymorphism in the CASP8 promoter region was associated with prostate cancer risk in a hospital-based case-control study of 406 Chinese prostate cancer patients and 408 age-matched cancerfree controls.Additionally,23 prostate cancer tissues were analyzed for CASP8 mRNA expression.We found a significantly decreased prostate cancer risk for the 6N ins/del genotype [adjusted odds ratio (OR)=0.68;95% confidence interval (CI)=0.51-0.92] and del/del genotype (OR=0.34;95% CI=0.19-0.63) compared with the ins/ins genotype.The 6N del allele was associated dose-dependently with decreased prostate cancer risk (P trend=0.001).RT-PCR showed that individuals with the 6N del allele had lower CASP8 mRNA levels than those with the ins/ins genotype (P=0.024).These findings suggested that the CASP8-652 6N ins/del polymorphism may affect the susceptibility to prostate cancer and reduce prostate cancer risk among Chinese men. | Guangbo Fu Jialin Tang Meilin Wang Chao Qin Fu Yan Qi Ding Changjun Yn Xinru Wang Zhengdong Zhang | 2011 | The Journal of Biomedical Research2011，25，2： | 0 |
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