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| 1 | Discovery of ~4.0 Ga detrital zircons in the Changdu Block,North Qiangtang,Tibetan Plateau显示文摘在 situ 锆石由 LA-ICP-MS 和 MC-ICP-MS 标明日期使用, 3981 的由岩屑形成的锆石 ??? 鮼铧?? ? 裦蒚铩 ????? 偃 ?? 鮼 ?? 郥趽 ????腘 吗?? | ShiPing He RongShe Li Chao Wang HongFei Zhang WenHua Ji PuSheng Yu PingYang Gu Chao Shi | 2011 | Chinese Science Bulletin2011，56，7： | 9 |
| 2 | Subduction channel fluid-rock interaction:Indications from rutile-quartz veins within eclogite from the Yuka terrane,North Qaidam orogen显示文摘High-pressure(HP)or ultrahigh-pressure(UHP)rutile-quartz veins that form at mantle depths due to fluid-rock interaction can be used to trace the properties and behavior of natural fluids in subduction zones.To explore the fluid flow and the associated element mobility during deep subduction and exhumation of the continental crust,we investigated the major and trace elements of Ti-rich minerals.Additionally,U–Pb dating,trace element contents,and Lu–Hf isotopic composition of zircon grains in the UHP eclogite and associated rutile-quartz veins were examined in the North Qaidam UHP metamorphic belt,Yuka terrane.The zircon grains in the rutile-quartz veins have unzoned or weak oscillatory zonings,and show low Th/U ratios,steep chondrite-normalized patterns of heavy rare earth elements(HREEs),and insignificant negative Eu anomalies,indicating their growth in metamorphic fluids.These zircon grains formed in 4313 Ma,which is consistent with the 4322 Ma age of the host eclogite.As for the zircons in the rutile-quartz veins,they showed steep HREE patterns on one hand,and were different from the zircons present in the host eclogite on the other.This demonstrates that their formation might have been related to the breakdown of the early stage of garnet,which corresponds to the abundance of fluids during the early exhumation stage.The core-rim profile analyses of rutile recorded a two-stage rutile growth across a large rutile grain;the rutile core has higher Nb,Ta,W,and Zr contents and lower Nb/Ta ratios than the rim,indicating that the rutile domains grew in different metamorphic fluids from the core towards the rim.The significant enrichment of high field strength elements(HFSEs)in the rutile core suggests that the peak fluids have high solubility and transportation capacity of these HFSEs.Furthermore,variations in the Nb vs.Cr trends in rutile indicate a connection of rutile to mafic protolith.The zircon grains from both the rutile-quartz veins and the host eclogite have similar Hf isotopic compositions,indicating that the vein-forming fluids are internally derived from the host eclogite.These fluids accumulated in the subduction channel and were triggered by local dehydration of the deeply subducted eclogite during the early exhumation conditions. | Xin Chen Youye Zheng Rongke Xu Pingyang Gu Jiyuan Yu Jie Bai Pengjie Cai Xiaojia Jiang | 2020 | Geoscience Frontiers2020，11，2： | 3 |
| 3 | Geochronological and geo-chemical study of the Darbut Ophiolitic Complex in theWest Junggar (NW China) : Implications for petrogenesisand tectonic evolution 显示文摘 | Yang Gaoxue Li Yongjun Gu Pingyang Yang Baokai Tong Lili Zhang Hongwei | 2012 | Gondwana Research2012，21，4： | 1 |
| 4 | KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B显示文摘Epilepsy is a common and severe brain disease affecting>65 million people worldwide.Recent studies have shown that kinesin superfamily motor protein 17(KIF17)is expressed in neurons and is involved in regulating the dendrite-targeted transport of N-methyl-D-aspartate receptor subtype 2B(NR2B).However,the effect of KIF17 on epileptic seizures remains to be explored.We found that KIF17 was mainly expressed in neurons and that its expression was increased in epileptic brain tissue.In the kainic acid(KA)-induced epilepsy mouse model,KIF17 overexpression increased the severity of epileptic activity,whereas KIF17 knockdown had the opposite effect.In electrophysiological tests,KIF17 regulated excitatory synaptic transmission,potentially due to KIF17-mediated NR2B membrane expression.In addition,this report provides the first demonstration that KIF17 is modified by SUMOylation(SUMO,small ubiquitin-like modifier),which plays a vital role in the stabilization and maintenance of KIF17 in epilepsy. | Yan Liu Xin Tian Pingyang Ke Juan Gu Yuanlin Ma Yi Guo Xin Xu Yuanyuan Chen Min Yang Xuefeng Wang Fei Xiao | 2022 | Neuroscience Bulletin2022，38，8： | 0 |
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