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| 1 | 口服西地那非疗法治疗严重肺动脉高压的效果研究显示文摘 | Singh TP Rohit M Grover A 菅鑫妍 | 2006 | 中国处方药2006，，8： | 49 |
| 2 | Lubiprostone vs Senna in postoperative orthopedic surgery patients with opioid-induced constipation:A double-blind,active-comparator trial显示文摘AIM:To investigate the efficacy of lubiprostone compared to Senna on bowel symptoms and constipation in post-operative orthopedic patients treated with opioids.METHODS:In this double blind,randomized,active comparator trial,adults who required opioids for analgesia following orthopedic procedures and who were admitted in inpatient rehabilitation were randomized following baseline assessments to lubiprostone(Amitza),orally twice aday or Senna(generic)two capsules administered daily for six days.Subjects were assessed using the patient assessment of constipation(PAC)-symptoms(PAC-SYM)and the PAC-quality of life(PAC-QOL)scales measured at baseline and Day 7;Subjects were assessed daily for secondary measures included the Bristol stool scale bowel consistency,specific bowel symptom score(Nausea,cramping,straining,completeness,abdominal pain,time per lavatory attempt,assistance needed),adverse events and rescue medications required.Function was measured using the functional independence measure(FIM)at admission and discharge;length of stay(LOS)and missed treatments due to gastrointestinal symptoms were also assessed.RESULTS:64 adults were enrolled;56 participants(28 in each group)had baseline and follow up measures and were included in the intention to treat(ITT)analyses.43 participants completed the study,21 in the active lubiprostone and 22 in the active Senna group.The mean age of the participants was 71.5years(SD=11.4 years,range:28-96 years).In the ITT analyses,participants showed significant improvement in bowel symptoms as measured by the PACSYM(mean±SD,-0.28±0.60,range:-1-2.33)and PAC-QOL(mean±SD,0.33±0.81,range:-1.5-2.0)over time,but there were no significant differences between the lubiprostone and Senna groups in mean change in the PAC-SYM(-0.20±0.60 vs-0.36±0.61,P=0.61 respectively)or the PAC-QOL(0.29±0.76 vs0.37±0.87,P=0.61 respectively).The mean change in each bowel symptom also did not significantly differ between treatment groups on ITT analyses,except for completeness of bowel movement,with the Senna group showing greater negative mean change in bowel movement completeness(-0.56±1.01 vs-2.00±1.41,P=0.03)and for reduction of abdominal pain,favoring Senna(-0.14±0.73 vs-0.73±1.08,P=0.04).Fifteen(75%)participants in the lubiprostone and in the Senna group requested rescue treatments.Participants made significant functional improvement from admission to discharge over a median LOS of 12 d,with a mean FIM change of 29.13±13.58 and no significant between group differences(27.0±9.2 vs 31.5±16.6,P=0.27).CONCLUSION:Both lubiprostone and Senna improved constipation-related symptoms and QOL in opioid-induced constipation,with no significant between-group differences. | Christina M Marciniak Santiago Toledo Jungwhalia Lee Michael Jesselson Jillian Bateman Benjamin Grover Joy Tierny | 2014 | World Journal of Gastroenterology2014，20，43： | 7 |
| 3 | Simulation in endoscopy:Practical educational strategies to improve learning显示文摘In gastrointestinal endoscopy, simulation-based training can help endoscopists acquire new skills and accelerate the learning curve. Simulation creates an ideal environment for trainees, where they can practice specific skills, perform cases at their own pace, and make mistakes with no risk to patients. Educators also benefit from the use of simulators, as they can structure training according to learner needs and focus solely on the trainee. Not all simulation-based training,however, is effective. To maximize benefits from this instructional modality,educators must be conscious of learners' needs, the potential benefits of training,and associated costs. Simulation should be integrated into training in a manner that is grounded in educational theory and empirical data. In this review, we focus on four best practices in simulation-based education: deliberate practice with mastery learning, feedback and debriefing, contextual learning, and innovative educational strategies. For each topic, we provide definitions,supporting evidence, and practical tips for implementation. | Rishad Khan Michael A Scaffidi Samir C Grover Nikko Gimpaya Catharine M Walsh | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，3： | 3 |
| 4 | Accumulation of an- tibacterial sesquiterpenoids in bacterially inoculated Gossypi- um leaves and cotyledons 显示文摘 | Essenberg M Grover P B Cover E C | 1990 | Phytochemistry1990，29，： | 1 |
| 5 | Small intestinal bacterial overgrowth in irritable bowel syndrome:association with colon motility,bowel symptoms,and psychological distress显示文摘 | Grover M Kanazawa M Palsson O S | 2008 | Neumgastroenterol Motil2008，20，9： | 1 |
| 6 | Proven technologies manage olefin plant's spent caustic显示文摘 | Grover R Gomaa H M | 1993 | Hydrocarbon Processing1993，72，9： | 1 |
| 7 | The effects of negative affectivity, hier- archical status, and self- determination on workplace victimization显示文摘 | Aquino K Grover S L Bradfield M and Allen D G | 1999 | Academy of Man agement Journal1999，，： | 1 |
| 8 | Structure of Very High Thermal Conductance显示文摘 | Grover G M Cotter T P Erikson G F | | 0，，06： | 1 |
| 9 | Computer playfulness and anxiety: positive and negative mediators of the system experience effect on perceived ease of use 显示文摘 | Hackbarth C Grover V Yi M Y | 2003 | Information & Management2003，40，3： | 1 |
| 10 | The prevention of haematoma following rhytidectomy: a review of 1078 consecutive faeelifts显示文摘 | GROVER R JONES B M WATERHOUSE N | 2001 | Br J Plast Surg2001，54，6： | 1 |
| 11 | Theoretical perspectives on the outsourcing of information systems显示文摘 | CHEON M GROVER V TENG J | 1995 | Journal of Information Technology1995，10，20： | 1 |
| 12 | Ultrastruc- tural differences between diabetic and idiopathic gastroparesis显示文摘 | Faussone-Pellegrini MS Grover M Pasricha PJ | 2012 | J Cell Mol Med2012，16，7： | 1 |
| 13 | Evaluating the incremental benefits of raising high-density lipoprotein cholesterol levels during lipid therapy after adjustment for the reductions in other blood lipid levels显示文摘 | Grover SA Kaouache M Joseph L | 2009 | Arch Intern Med2009，169，19： | 1 |
| 14 | Silent myocardial ischaemia and haemoglobin concentration:a randomized controlled trial of transfusion strategy in lower limb arthroplasty显示文摘 | Grover M Talwalkar MS Casbard A | 2006 | Vox Sanguinis2006，90，2： | 1 |
| 15 | The Effect of Service Quality and Partnership on the Outsoureing of Information Systems Functions 显示文摘 | Grover V Cheon M J Teng J T C | 1996 | Journal of Management Information Systems1996，12，4： | 1 |
| 16 | Monolithic membrane valves and diaphragm pumps for practical large- scale integration into glass microfluidic devices 显示文摘 | GROVER W SKELLEY A M LIU C N | 2003 | Sens Actuators: B2003，89，3： | 1 |
| 17 | Refractory clostridium difficile-associated diarrhea 显示文摘 | Grover S Hamilton M J Carr-locke DL | 2007 | Med Gen Med2007，9，2： | 1 |
| 18 | Reducing complications in eervicofaeial rhytideetomy by tumeseent infiltration: a comparative trial evaluating 678 eonsecutive face lifts 显示文摘 | JONES B M GROVER R | 2004 | Plast Reeonstr Surg2004，113，1： | 1 |
| 19 | REM sleep deprivation inhibits LTP in vivo in area CA1 of rat hippocampus 显示文摘 | Eun Young Kim Ghada S Mahmoud Lawrence M Grover | 2005 | Neurosci Lett2005，388，3： | 1 |
| 20 | Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction 显示文摘 | BURG J L GROVER C M POULETTY P | 1989 | Journal of Clinical Microbiology1989，27，8： | 1 |
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