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| 1 | Neurocognitive Graphs of First-Episode Schizophrenia and Major Depression Based on Cognitive Features显示文摘Neurocognitive deficits are frequently observed in patients with schizophrenia and major depressive disorder(MDD). The relations between cognitive features may be represented by neurocognitive graphs based on cognitive features, modeled as Gaussian Markov random fields. However, it is unclear whether it is possible to differentiate between phenotypic patterns associated with the differential diagnosis of schizophrenia and depression using this neurocognitive graph approach. In this study, we enrolled 215 first-episode patients with schizophrenia(FES), 125 with MDD, and 237 demographically-matched healthy controls(HCs). The cognitive performance of all participants was evaluated using a battery of neurocognitive tests. The graphical LASSO model was trained with aone-vs-one scenario to learn the conditional independent structure of neurocognitive features of each group. Participants in the holdout dataset were classified into different groups with the highest likelihood. A partial correlation matrix was transformed from the graphical model to further explore the neurocognitive graph for each group. The classification approach identified the diagnostic class for individuals with an average accuracy of 73.41% for FES vs HC, 67.07% for MDD vs HC, and 59.48% for FES vs MDD. Both of the neurocognitive graphs for FES and MDD had more connections and higher node centrality than those for HC. The neurocognitive graph for FES was less sparse and had more connections than that for MDD.Thus, neurocognitive graphs based on cognitive features are promising for describing endophenotypes that may discriminate schizophrenia from depression. | Sugai Liang Roberto Vega Xiangzhen Kong Wei Deng Qiang Wang Xiaohong Ma Mingli Li Xun Hu Andrew J.Greenshaw Russell Greiner Tao Li | 2018 | Neuroscience Bulletin2018，34，2： | 6 |
| 2 | Correlation of lipid layer thickness measurements with fluorescein tear film break-up time and Schirmer's test显示文摘 | Isreb MA Greiner JV Korb DR | 2003 | Eye2003，17，1： | 1 |
| 3 | B-type natriuretic peptide level and postdischarge thrombotic events in older patients hospitalized with heart failure: insights from the Acute Decompensated Heart Failure National Registry显示文摘 | Kociol RD Greiner MA Hammill BG | 2012 | Am Heart J2012，163，6： | 1 |
| 4 | Relationship between early physician follow - up and 30 - day readmission among Medicare beneficiaries hospitalized for heart failure显示文摘 | Hernandez AF Greiner MA Fonarow GC | 2010 | JAMA2010，303，17： | 1 |
| 5 | Humanized mice for the study of type 1 and type 2 diabetes显示文摘 | Greiner DL Brehm MA Hosur V | 2011 | N Engl J Med2011，1245，： | 1 |
| 6 | B-type na- triuretic peptide level and postdischarge thrombotic events in older patients hospitalized with heart failure: Insights from the Acute Decompensated Heart Failure National Registry 显示文摘 | KOCIOL RD GREINER MA HAMMILL BG | 2012 | Am Heart J2012，163，6： | 1 |
| 7 | Relationship between early physician follow-up and 30-dayreadmission among medicare beneficiaries hospitalized forheart failure显示文摘 | Hernandez AF Greiner MA Fonarow GC | 2010 | JAMA2010，303，17： | 1 |
| 8 | Associations be- tween wors-ening renal function and 30-day outcomes among Medicarebeneficiaries hospitalized with heart failure 显示文摘 | Patel UD Greiner MA Fonarow GC | 2010 | A- merican Heart Journal2010，160，1： | 1 |
| 9 | Prevalence and site specificity of Sarcocystis greineri sarcosysts in Virginia opossum(Didelphis virginiana) in florida 显示文摘 | Baird KL Cheadle MA Greiner EC | 2002 | J Parasitol2002，88，3： | 1 |
| 10 | Epidermiology of Anthraeycline Cardiotoxicity in Children and Adults显示文摘 | Greiner MA Lipshultz SE | 1998 | Semin Oncol1998，25，： | 1 |
| 11 | Humanized mice for the study of type 1 and type 2 diabetes 显示文摘 | Greiner DL Brehm MA Hosur V | 2011 | N Engl J Med2011，，： | 1 |
| 12 | Early and long-term outcomes of heart failure in elderly persons, 2001 - 2005 显示文摘 | Curtis LH Greiner MA Hammill BG | 2008 | Arch Intern Med2008，168，22： | 1 |
| 13 | Long-term complications associated with glaucoma drainage devices and Boston keratoprosthesis显示文摘 | Li JY Greiner MA Brandt JD | 2011 | Am J Ophthalmol2011，152，2： | 1 |
| 14 | T-cell activation and transplantation tolerance显示文摘 | Priyadharshini B Greiner DL Brehm MA | | 0，，： | 1 |
| 15 | QRS duration,bundle-branch block morphology, and outcomes among older patientswith heart failure receiving cardiac resynchronization therapy显示文摘 | Peterson PN Greiner MA Qualls LG | 2013 | JAMA2013，310，6： | 1 |
| 16 | 查看详情显示文摘 | J Simon W S Bakr R Ma M E Tai P M Preiss and M Greiner | | 0，，7343： | 1 |
| 17 | B-type natri- uretic peptide level and postdischarge thrombotic events in ol der patients hospitalized with heart failure: insights from the Acute Decompensated Heart Failure National Registry显示文摘 | Kociol RD Greiner MA Hammill BG | 2012 | Am Heart J2012，163，6： | 1 |
| 18 | Cryoembeding and sectioning of cochleas for immunocytochemistry and in situ hybridization 显示文摘 | Whitlon DS Szakaly R Greiner MA | 2001 | Brain Research Protocols2001，6，： | 1 |
| 19 | Relationship between early physician follow-up and 30-day redmission among Medicare beneficiaries hospitalized for heart failure显示文摘 | Hernandez AF Greiner MA Fonarow GC | | Journal of the American Medical Association0，，： | 1 |
| 20 | Atrial fibrillation among Medicare beneficiaries hospitalized with sepsis: incidence and risk factors显示文摘 | Walkey AJ Greiner MA Heckbert SR | 2013 | Am Heart J2013，65，6： | 1 |
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