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| 1 | Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca^(2+) signaling pathway显示文摘Mobilization of intracellular Ca2+ stores is involved inmany diverse cell functions, including: cell proliferation;differentiation; fertilization; muscle contraction; secre-tion of neurotransmitters, hormones and enzymes;and lymphocyte activation and proliferation. Cyclic ad-enosine diphosphate ribose(cADPR) is an endogenousCa2+ mobilizing nucleotide present in many cell typesand species, from plants to animals. cADPR is formedby ADP-ribosyl cyclases from nicotinamide adenine di-nucleotide. The main ADP-ribosyl cyclase in mammalsis CD38, a multi-functional enzyme and a type Ⅱ mem-brane protein. It has been shown that many extracel-lular stimuli can induce cADPR production that leadsto calcium release or influx, establishing cADPR as asecond messenger. cADPR has been linked to a widevariety of cellular processes, but the molecular mecha-nisms regarding cADPR signaling remain elusive. Theaim of this review is to summarize the CD38/cADPR/Ca2+ signaling pathway, focusing on the recent advanc-es involving the mechanism and physiological functionsof cADPR-mediated Ca2+ mobilization. | Wenjie Wei Richard Graeff Jianbo Yue | 2014 | World Journal of Biological Chemistry2014，5，1： | 4 |
| 2 | Reciprocal space mapping of implanted AⅢBⅤ sem-iconductor compounds显示文摘 | WIETESKA K WIERZCHOWSKI W GRAEFF W | 2004 | Journal of Alloys and Compounds2004，362，： | 1 |
| 3 | ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP显示文摘 | Aarhus R Graeff R M Dickey D M | 1995 | J Biol Chem1995，270，30： | 1 |
| 4 | Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine NAADP synthesis and hydrolysis activities 显示文摘 | Graeff R Liu Q Kriksunov I A | 2006 | J Biol Chem2006，281，28： | 1 |
| 5 | Racl in human breast cancer: Ovcrexpression, mutation analysis, and characterization of a new isoform, Racl b 显示文摘 | Sehnelzer A Prechtel D Knaus U Dehne K Gerhard M Graeff H | 2000 | Oncogene2000，19，26： | 1 |
| 6 | The impact of economic freedom on corruption:different patterns for rich and poor countries显示文摘 | Graeff P Mehlkop G | | 0，，03： | 1 |
| 7 | High resolution quantitative computed tomography-based as- sessment of trabecular microstructure and strength estimates by finite-el- ement analysis of the spine,but not DXA, reflects vertebral fracture sta- tus in men with glucocorticoid-induced osteoporosis 显示文摘 | Graeff C | 2013 | Bone2013，52，2： | 1 |
| 8 | Prognostic signifi- cance of symptoms of hospitalized advanced cancer patients 显示文摘 | Teunissen SC de Graeff A Haes HC | 2006 | Eur J Cancer2006，42，15： | 1 |
| 9 | Dual role of 5-HT in defense and anxiety显示文摘 | Graeff FG Viana MB Mora PO | 1997 | Neurosci Biobehav Rev1997，21，： | 1 |
| 10 | Solid state nitric oxide sensor using a latex rubber matrix显示文摘 | HERCULANO R D BRUNELLO C A GRAEFF C F O | 2006 | Macromolecular Symposia2006，，1： | 1 |
| 11 | Evolution of situational leadership theory: A critical review 显示文摘 | Graeff C L | 1997 | Leadership Quarterly1997，8，2： | 1 |
| 12 | Oral administration of cyclosporin does not prevent expansion of antigen-specific, gut-associated, and spleen lymphocyte populations duringChlamydia trachomatis proctitis in nonhuman primates显示文摘 | Dr. Martin Zeitz Thomas C. Quinn Alan S. Graeff Roland Schwarting Stephen P. James | 1989 | Digestive Diseases and Sciences1989，，4： | 1 |
| 13 | Pretreatment fac- tors predicting quality of life after treatment for head and neck cancer显示文摘 | de Graeff A de Leeuw JR Ros WJ | 2000 | Head Neck2000，22，4： | 1 |
| 14 | Analysis of some organochlorine pesticides in an urban atmosphere (Strasbourg, east of France)显示文摘 | Scheyer A Graeff C Morville S el al | 2005 | Chemosphere2005，58，11： | 1 |
| 15 | Optimization of a novel nitric oxide sensor using a latex rubber matrix显示文摘 | HERCULANO R D BRUNELLO C A GRAEFF C F O | 2007 | Journal of Applied Sciences2007，7，23： | 1 |
| 16 | Effects of angiotensin Ⅱ and captopril on inducible sustained ventricular tachycardia two weeks after myocardial infarction in the pig显示文摘 | de Langen CD de Graeff PA van Gilst WH | 1989 | J Cardiovasc Pharmacol1989，13，2： | 1 |
| 17 | Oral filament proteins and their reg ulation in Tetrahymena pyriformis显示文摘 | Williams N E Honts JE Graeff RW | 1986 | Exp Cell Res1986，164，： | 1 |
| 18 | Administration of romosozumab improves vertebral trabecular and cortical bone as assessed with quantitative computed tomography and finite element analysis显示文摘 | GRAEFF C CAMPBELL G M PENA J | 2015 | Bone2015，81，： | 1 |
| 19 | Abscisic acid signaling through cyclic ADP-ribose in plants 显示文摘 | Wu Y Kuzma J Marechal E Graeff R Lee H C | 1997 | Science1997，278，： | 1 |
| 20 | Effects of angiotensin ii and captopril on inducible sustained ventricular tachycardia two weeks after myocardial infarction in the pig 显示文摘 | de Langen C D de Graeff P A van Gilst W H | 1989 | J Cardiovasc Pharmacol1989，13，2： | 1 |
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